Pax5 (paired box 5) - Rat Genome Database

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Gene: Pax5 (paired box 5) Mus musculus
Analyze
Symbol: Pax5
Name: paired box 5
RGD ID: 1621602
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryonic cranial skeleton morphogenesis; skeletal muscle cell differentiation; and telencephalon development. Located in nucleus. Is expressed in several structures, including central nervous system; future brain; immune system; liver; and urinary system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human PAX5 (paired box 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B-cell-specific transcription factor; BSAP; EBB-1; KLP; paired box gene 5; paired box protein Pax-5; Pax; Pax-5; Pax5 variant 1; Pax5 variant 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39444,524,748 - 44,710,694 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl444,524,757 - 44,710,487 (-)EnsemblGRCm39 Ensembl
GRCm38444,524,748 - 44,710,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl444,524,757 - 44,710,487 (-)EnsemblGRCm38mm10GRCm38
MGSCv37444,544,378 - 44,723,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36444,552,606 - 44,731,540 (-)NCBIMGSCv36mm8
Celera444,550,836 - 44,729,998 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map423.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal auditory brainstem response  (IEA)
abnormal B cell differentiation  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal cell adhesion  (IAGP)
abnormal cell migration  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellar lobule formation  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebellum vermis morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal hindbrain development  (IAGP)
abnormal humoral immune response  (IEA)
abnormal immunoglobulin heavy chain V(D)J recombination  (IAGP)
abnormal late pro-B cell  (IAGP)
abnormal lymphopoiesis  (IAGP)
abnormal pro-B cell morphology  (IAGP)
absent B-2 B cells  (IAGP)
absent late pro-B cells  (IAGP)
absent mature B cells  (IAGP)
arrested B cell differentiation  (IAGP)
decreased B cell number  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased B-1b cell number  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased IgA level  (IEA)
decreased IgD level  (IEA)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG2a level  (IEA)
decreased IgG2b level  (IEA)
decreased IgG3 level  (IAGP)
decreased IgM level  (IEA)
decreased immature B cell number  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased inferior colliculus size  (IAGP)
decreased leukocyte cell number  (IEA)
decreased mature B cell number  (IAGP)
decreased pre-B cell number  (IAGP)
dilated lateral ventricle  (IAGP)
domed cranium  (IAGP)
hydrocephaly  (IAGP)
hyperactivity  (IEA)
immune system phenotype  (IEA)
impaired glucose tolerance  (IEA)
impaired humoral immune response  (IEA)
increased anxiety-related response  (IAGP)
increased B cell acute lymphoblastic leukemia incidence  (IAGP)
increased B-1 B cell number  (IEA)
increased CD4-positive NK T cell number  (IEA)
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
increased CD8-positive, alpha-beta memory T cell number  (IEA)
increased circulating amylase level  (IEA)
increased circulating lipase level  (IEA)
increased circulating triglyceride level  (IEA)
increased locomotor activity  (IAGP)
increased macrophage cell number  (IEA)
increased memory-marker CD4-positive NK T cell number  (IEA)
increased monocyte cell number  (IEA)
increased single-positive T cell number  (IEA)
increased T cell number  (IAGP)
lethality at weaning, complete penetrance  (IAGP)
limb grasping  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1283313   PMID:1375324   PMID:1516825   PMID:1685142   PMID:1730258   PMID:2116362   PMID:7508415   PMID:7542362   PMID:7577673   PMID:7630627   PMID:7774911   PMID:7777508  
PMID:7883790   PMID:7981748   PMID:8001125   PMID:8001127   PMID:8126546   PMID:8406007   PMID:8431641   PMID:8521821   PMID:8575294   PMID:8625814   PMID:8650231   PMID:8756299  
PMID:8790871   PMID:8835542   PMID:8848044   PMID:8951055   PMID:9042861   PMID:9092562   PMID:9133423   PMID:9159136   PMID:9405645   PMID:9409663   PMID:9442394   PMID:9545244  
PMID:9705955   PMID:10022910   PMID:10192389   PMID:10197584   PMID:10328847   PMID:10349636   PMID:10354469   PMID:10518499   PMID:10524622   PMID:10662641   PMID:10748034   PMID:10751172  
PMID:10934015   PMID:10940892   PMID:11042159   PMID:11076861   PMID:11124114   PMID:11160324   PMID:11217851   PMID:11241288   PMID:11242053   PMID:11420047   PMID:11477548   PMID:11493561  
PMID:11500373   PMID:11704761   PMID:11799127   PMID:11869689   PMID:12008032   PMID:12044782   PMID:12052884   PMID:12098702   PMID:12244173   PMID:12384151   PMID:12387741   PMID:12406913  
PMID:12466851   PMID:12479824   PMID:12514097   PMID:12560221   PMID:12874218   PMID:12881423   PMID:14512296   PMID:14581609   PMID:14594818   PMID:14610273   PMID:14647274   PMID:14965345  
PMID:15004008   PMID:15007090   PMID:15067064   PMID:15094381   PMID:15258579   PMID:15356142   PMID:15361869   PMID:15514019   PMID:15557148   PMID:15580273   PMID:15618518   PMID:15719364  
PMID:15872002   PMID:15872005   PMID:15967678   PMID:16025120   PMID:16141072   PMID:16141073   PMID:16243425   PMID:16292344   PMID:16407117   PMID:16482219   PMID:16530751   PMID:16546096  
PMID:16618805   PMID:16680144   PMID:16709844   PMID:16782087   PMID:16930724   PMID:16968900   PMID:17098231   PMID:17101802   PMID:17111353   PMID:17166926   PMID:17312149   PMID:17513763  
PMID:17658281   PMID:17671180   PMID:17717600   PMID:17851532   PMID:18172866   PMID:18209069   PMID:18287559   PMID:18522499   PMID:18552207   PMID:18562282   PMID:18644860   PMID:18676810  
PMID:18812467   PMID:18991270   PMID:19340306   PMID:19345119   PMID:19549820   PMID:19703295   PMID:20059953   PMID:20498068   PMID:20826759   PMID:20932939   PMID:21267068   PMID:21303848  
PMID:21349430   PMID:21357426   PMID:21549805   PMID:21552207   PMID:21606506   PMID:21677750   PMID:21731673   PMID:21858141   PMID:21873635   PMID:22147266   PMID:22308434   PMID:22473956  
PMID:22474389   PMID:22593617   PMID:22669466   PMID:22724066   PMID:22807088   PMID:22807655   PMID:22927250   PMID:22956488   PMID:22988430   PMID:23019372   PMID:23349049   PMID:23375831  
PMID:23449333   PMID:23684985   PMID:23973221   PMID:24078629   PMID:24747640   PMID:24939936   PMID:24952961   PMID:25288398   PMID:25288399   PMID:25573326   PMID:25838350   PMID:25855603  
PMID:26056231   PMID:26073757   PMID:26269126   PMID:26301816   PMID:26408659   PMID:26456157   PMID:26843424   PMID:26988119   PMID:27107743   PMID:27913602   PMID:27913604   PMID:28009285  
PMID:28219927   PMID:28533268   PMID:29134420   PMID:29490943   PMID:29880490   PMID:30089192   PMID:30323344   PMID:30498131   PMID:30643249   PMID:31381561   PMID:31729420   PMID:31804490  
PMID:32553121   PMID:32612238   PMID:32703236   PMID:33053343   PMID:33154497   PMID:33469032   PMID:33619557   PMID:33672551   PMID:34021049   PMID:34301800   PMID:34321664   PMID:34824296  
PMID:34906895   PMID:35131871   PMID:35156727   PMID:35645295   PMID:35700056   PMID:36064939   PMID:36656641   PMID:36730754   PMID:36745673   PMID:37298722   PMID:37337907   PMID:37620322  
PMID:37725138   PMID:38355793  


Genomics

Comparative Map Data
Pax5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39444,524,748 - 44,710,694 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl444,524,757 - 44,710,487 (-)EnsemblGRCm39 Ensembl
GRCm38444,524,748 - 44,710,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl444,524,757 - 44,710,487 (-)EnsemblGRCm38mm10GRCm38
MGSCv37444,544,378 - 44,723,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36444,552,606 - 44,731,540 (-)NCBIMGSCv36mm8
Celera444,550,836 - 44,729,998 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map423.55NCBI
PAX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38936,833,269 - 37,034,268 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl936,833,269 - 37,034,268 (-)EnsemblGRCh38hg38GRCh38
GRCh37936,833,266 - 37,034,265 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36936,828,531 - 37,024,476 (-)NCBINCBI36Build 36hg18NCBI36
Build 34936,828,530 - 37,024,476NCBI
Celera936,771,847 - 36,967,843 (-)NCBICelera
Cytogenetic Map9p13.2NCBI
HuRef936,784,641 - 36,985,496 (-)NCBIHuRef
CHM1_1936,834,374 - 37,035,683 (-)NCBICHM1_1
T2T-CHM13v2.0936,856,835 - 37,057,984 (-)NCBIT2T-CHM13v2.0
Pax5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8563,554,784 - 63,741,380 (-)NCBIGRCr8
mRatBN7.2558,763,334 - 58,945,719 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl558,765,036 - 58,944,326 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx560,744,271 - 60,923,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0562,563,059 - 62,742,070 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0562,532,699 - 62,711,294 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0560,007,587 - 60,191,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl560,007,587 - 60,191,941 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0564,530,218 - 64,707,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4561,016,708 - 61,131,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera557,341,131 - 57,518,116 (-)NCBICelera
Cytogenetic Map5q22NCBI
Pax5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541929,395,389 - 29,570,952 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541929,395,631 - 29,577,272 (+)NCBIChiLan1.0ChiLan1.0
PAX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,558,133 - 87,631,819 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1987,573,981 - 87,637,726 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0936,677,369 - 36,876,678 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1937,474,267 - 37,673,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl937,474,267 - 37,673,684 (-)Ensemblpanpan1.1panPan2
PAX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11153,194,905 - 53,390,204 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1153,201,344 - 53,390,974 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1151,785,891 - 51,981,004 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01154,304,295 - 54,499,334 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1154,303,708 - 54,499,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11152,803,918 - 52,998,984 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01152,832,452 - 53,027,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01153,528,788 - 53,723,946 (-)NCBIUU_Cfam_GSD_1.0
Pax5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947168,146,873 - 168,333,200 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365244,700,841 - 4,887,106 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365244,700,815 - 4,887,035 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1237,575,061 - 237,785,413 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11237,574,938 - 237,785,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21265,431,252 - 265,635,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PAX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11243,547,399 - 43,748,202 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1243,548,914 - 43,740,962 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603840,624,837 - 40,822,776 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pax5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624930491,892 - 667,530 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624930491,220 - 660,476 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pax5
6049 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4439
Count of miRNA genes:717
Interacting mature miRNAs:890
Transcripts:ENSMUST00000014174, ENSMUST00000102932, ENSMUST00000107825, ENSMUST00000107826, ENSMUST00000107827, ENSMUST00000134968, ENSMUST00000143235, ENSMUST00000146335, ENSMUST00000165417, ENSMUST00000172866, ENSMUST00000172949, ENSMUST00000173733, ENSMUST00000173821, ENSMUST00000174242, ENSMUST00000174319, ENSMUST00000174761
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse

Markers in Region
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
cM Map420.7UniSTS
cM Map420.7UniSTS
D4Mit257  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38444,709,353 - 44,709,486UniSTSGRCm38
MGSCv37444,722,225 - 44,722,358UniSTSGRCm37
Celera444,728,911 - 44,729,044UniSTS
Cytogenetic Map4B1UniSTS
cM Map414.5UniSTS
Whitehead Genetic418.6UniSTS
Whitehead/MRC_RH4690.55UniSTS
Whitehead_YAC4 UniSTS
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
cM Map420.7UniSTS
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
Pax5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000014174   ⟹   ENSMUSP00000014174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,524,757 - 44,710,487 (-)Ensembl
GRCm38.p6 Ensembl444,524,757 - 44,710,487 (-)Ensembl
RefSeq Acc Id: ENSMUST00000102932   ⟹   ENSMUSP00000099996
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,145 - 44,710,418 (-)Ensembl
GRCm38.p6 Ensembl444,531,145 - 44,710,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107825   ⟹   ENSMUSP00000103455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,145 - 44,710,418 (-)Ensembl
GRCm38.p6 Ensembl444,531,145 - 44,710,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107826   ⟹   ENSMUSP00000103457
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,145 - 44,710,418 (-)Ensembl
GRCm38.p6 Ensembl444,531,145 - 44,710,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107827   ⟹   ENSMUSP00000103458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,145 - 44,710,418 (-)Ensembl
GRCm38.p6 Ensembl444,531,145 - 44,710,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134968   ⟹   ENSMUSP00000133540
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000143235   ⟹   ENSMUSP00000134370
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,145 - 44,710,418 (-)Ensembl
GRCm38.p6 Ensembl444,531,145 - 44,710,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146335   ⟹   ENSMUSP00000139296
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,679,440 - 44,704,006 (-)Ensembl
GRCm38.p6 Ensembl444,679,440 - 44,704,006 (-)Ensembl
RefSeq Acc Id: ENSMUST00000165417   ⟹   ENSMUSP00000128880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172866   ⟹   ENSMUSP00000134119
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172949
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,569,971 - 44,683,815 (-)Ensembl
GRCm38.p6 Ensembl444,569,971 - 44,683,815 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173733   ⟹   ENSMUSP00000133671
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173821   ⟹   ENSMUSP00000134712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174242   ⟹   ENSMUSP00000134391
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174319   ⟹   ENSMUSP00000133978
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,497 - 44,710,408 (-)Ensembl
GRCm38.p6 Ensembl444,531,497 - 44,710,408 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,679,454 - 44,703,413 (-)Ensembl
GRCm38.p6 Ensembl444,679,454 - 44,703,413 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186542   ⟹   ENSMUSP00000141186
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,679,454 - 44,703,413 (-)Ensembl
GRCm38.p6 Ensembl444,679,454 - 44,703,413 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187197
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,679,454 - 44,703,413 (-)Ensembl
GRCm38.p6 Ensembl444,679,454 - 44,703,413 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,679,454 - 44,703,413 (-)Ensembl
GRCm38.p6 Ensembl444,679,454 - 44,703,413 (-)Ensembl
RefSeq Acc Id: ENSMUST00000194075   ⟹   ENSMUSP00000141303
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl444,531,504 - 44,645,723 (-)Ensembl
GRCm38.p6 Ensembl444,531,504 - 44,645,723 (-)Ensembl
RefSeq Acc Id: NM_008782   ⟹   NP_032808
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39444,524,748 - 44,710,694 (-)NCBI
GRCm38444,524,748 - 44,710,694 (-)NCBI
MGSCv37444,544,378 - 44,723,312 (-)RGD
Celera444,550,836 - 44,729,998 (-)RGD
cM Map4 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_032808   ⟸   NM_008782
- UniProtKB: Q02650 (UniProtKB/Swiss-Prot),   A2AKM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000134370   ⟸   ENSMUST00000143235
RefSeq Acc Id: ENSMUSP00000141186   ⟸   ENSMUST00000186542
RefSeq Acc Id: ENSMUSP00000134119   ⟸   ENSMUST00000172866
RefSeq Acc Id: ENSMUSP00000103457   ⟸   ENSMUST00000107826
RefSeq Acc Id: ENSMUSP00000103455   ⟸   ENSMUST00000107825
RefSeq Acc Id: ENSMUSP00000103458   ⟸   ENSMUST00000107827
RefSeq Acc Id: ENSMUSP00000014174   ⟸   ENSMUST00000014174
RefSeq Acc Id: ENSMUSP00000139296   ⟸   ENSMUST00000146335
RefSeq Acc Id: ENSMUSP00000128880   ⟸   ENSMUST00000165417
RefSeq Acc Id: ENSMUSP00000134391   ⟸   ENSMUST00000174242
RefSeq Acc Id: ENSMUSP00000133978   ⟸   ENSMUST00000174319
RefSeq Acc Id: ENSMUSP00000141303   ⟸   ENSMUST00000194075
RefSeq Acc Id: ENSMUSP00000133540   ⟸   ENSMUST00000134968
RefSeq Acc Id: ENSMUSP00000133671   ⟸   ENSMUST00000173733
RefSeq Acc Id: ENSMUSP00000134712   ⟸   ENSMUST00000173821
RefSeq Acc Id: ENSMUSP00000099996   ⟸   ENSMUST00000102932
Protein Domains
Paired   Paired-box protein 2 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q02650-F1-model_v2 AlphaFold Q02650 1-391 view protein structure

Promoters
RGD ID:6835821
Promoter ID:MM_KWN:37431
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:OTTMUST00000015402,   OTTMUST00000015403,   OTTMUST00000015561,   OTTMUST00000015562,   OTTMUST00000015563,   OTTMUST00000015564
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36444,723,421 - 44,723,921 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97489 AgrOrtholog
Ensembl Genes ENSMUSG00000014030 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000014174 ENTREZGENE
  ENSMUST00000014174.14 UniProtKB/Swiss-Prot
  ENSMUST00000102932.10 UniProtKB/TrEMBL
  ENSMUST00000107825.9 UniProtKB/TrEMBL
  ENSMUST00000107826.9 UniProtKB/TrEMBL
  ENSMUST00000107827.9 UniProtKB/TrEMBL
  ENSMUST00000134968.9 UniProtKB/TrEMBL
  ENSMUST00000143235.8 UniProtKB/TrEMBL
  ENSMUST00000146335.8 UniProtKB/TrEMBL
  ENSMUST00000165417.9 UniProtKB/TrEMBL
  ENSMUST00000172866.8 UniProtKB/TrEMBL
  ENSMUST00000173733.8 UniProtKB/TrEMBL
  ENSMUST00000173821.8 UniProtKB/TrEMBL
  ENSMUST00000174242.8 UniProtKB/TrEMBL
  ENSMUST00000174319.8 UniProtKB/TrEMBL
  ENSMUST00000186542.2 UniProtKB/TrEMBL
  ENSMUST00000194075.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAIRED_DNA_bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Paired_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pax2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAX_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18507 UniProtKB/Swiss-Prot
MGD MGI:97489 ENTREZGENE
NCBI Gene 18507 ENTREZGENE
PANTHER PAIRED BOX PROTEIN PAX-5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45636 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pax2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pax5 PhenoGen
PRINTS PAIREDBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PAIRED_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAIRED_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PAX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WST9_MOUSE UniProtKB/TrEMBL
  A0A0A6YVX2_MOUSE UniProtKB/TrEMBL
  A2AKM5_MOUSE UniProtKB/TrEMBL
  A2AKM6 ENTREZGENE, UniProtKB/TrEMBL
  A2AKM7_MOUSE UniProtKB/TrEMBL
  A2AKM8_MOUSE UniProtKB/TrEMBL
  G3UW65_MOUSE UniProtKB/TrEMBL
  G3UX39_MOUSE UniProtKB/TrEMBL
  G3UXF6_MOUSE UniProtKB/TrEMBL
  G3UY80_MOUSE UniProtKB/TrEMBL
  G3UYK4_MOUSE UniProtKB/TrEMBL
  G3UZ71_MOUSE UniProtKB/TrEMBL
  G3UZ86_MOUSE UniProtKB/TrEMBL
  G3V008_MOUSE UniProtKB/TrEMBL
  I6XNZ1_MOUSE UniProtKB/TrEMBL
  I6YXB9_MOUSE UniProtKB/TrEMBL
  PAX5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  V9GXS5_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-26 Pax5  paired box 5    paired box gene 5  Symbol and/or name change 5135510 APPROVED