Or1e21 (olfactory receptor family 1 subfamily E member 21) - Rat Genome Database

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Gene: Or1e21 (olfactory receptor family 1 subfamily E member 21) Mus musculus
Analyze
No known orthologs.
Symbol: Or1e21
Name: olfactory receptor family 1 subfamily E member 21
RGD ID: 1621264
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in central nervous system and retina. Orthologous to human OR1E1 (olfactory receptor family 1 subfamily E member 1); OR1E2 (olfactory receptor family 1 subfamily E member 2); and OR1E3 (olfactory receptor family 1 subfamily E member 3 (gene/pseudogene)).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2P1NL-3613021-3612086; MOR135; MOR135-1; olfactory receptor 380; olfactory receptor MOR135-1; Olfr380
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,344,101 - 73,345,036 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,343,712 - 73,348,334 (-)EnsemblGRCm39 Ensembl
GRCm381173,453,275 - 73,454,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,452,886 - 73,457,508 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,266,777 - 73,267,712 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,269,470 - 73,270,405 (-)NCBIMGSCv36mm8
Celera1180,988,715 - 80,989,650 (-)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:16602821   PMID:16805845   PMID:21873635   PMID:32295537   PMID:38355793  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:58
Interacting mature miRNAs:60
Transcripts:ENSMUST00000075532, ENSMUST00000121209
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse

Markers in Region
UniSTS:489497  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,453,275 - 73,454,210UniSTSGRCm38
GRCm381173,405,442 - 73,406,379UniSTSGRCm38
MGSCv371173,266,777 - 73,267,712UniSTSGRCm37
MGSCv371173,218,944 - 73,219,881UniSTSGRCm37
Celera1180,942,381 - 80,943,318UniSTS
Celera1180,988,715 - 80,989,650UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:494376  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,453,188 - 73,454,241UniSTSGRCm38
GRCm381173,405,355 - 73,406,410UniSTSGRCm38
MGSCv371173,266,690 - 73,267,743UniSTSGRCm37
MGSCv371173,218,857 - 73,219,912UniSTSGRCm37
Celera1180,942,294 - 80,943,349UniSTS
Celera1180,988,628 - 80,989,681UniSTS
Cytogenetic Map11B4UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000075532   ⟹   ENSMUSP00000074971
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,344,101 - 73,345,036 (-)Ensembl
GRCm38.p6 Ensembl1173,453,275 - 73,454,210 (-)Ensembl
RefSeq Acc Id: ENSMUST00000121209   ⟹   ENSMUSP00000112462
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,343,712 - 73,348,284 (-)Ensembl
GRCm38.p6 Ensembl1173,452,886 - 73,457,458 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127789   ⟹   ENSMUSP00000116228
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,343,712 - 73,348,334 (-)Ensembl
GRCm38.p6 Ensembl1173,452,886 - 73,457,508 (-)Ensembl
RefSeq Acc Id: NM_147025   ⟹   NP_667236
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391173,344,101 - 73,345,036 (-)NCBI
GRCm381173,453,275 - 73,454,210 (-)ENTREZGENE
MGSCv371173,266,777 - 73,267,712 (-)RGD
Celera1180,988,715 - 80,989,650 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_667236 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL60726 (Get FASTA)   NCBI Sequence Viewer  
  AAP70910 (Get FASTA)   NCBI Sequence Viewer  
  EDL12729 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000074971
  ENSMUSP00000074971.2
  ENSMUSP00000112462.2
  ENSMUSP00000116228.3
Reference Protein Sequences
RefSeq Acc Id: NP_667236   ⟸   NM_147025
- UniProtKB: Q8VGT3 (UniProtKB/TrEMBL),   B0QZP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000116228   ⟸   ENSMUST00000127789
RefSeq Acc Id: ENSMUSP00000112462   ⟸   ENSMUST00000121209
RefSeq Acc Id: ENSMUSP00000074971   ⟸   ENSMUST00000075532
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VGT3-F1-model_v2 AlphaFold Q8VGT3 1-311 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030214 AgrOrtholog
Ensembl Genes ENSMUSG00000072709 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075532 ENTREZGENE
  ENSMUST00000075532.2 UniProtKB/TrEMBL
  ENSMUST00000121209.3 UniProtKB/TrEMBL
  ENSMUST00000127789.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:259027 UniProtKB/TrEMBL
MGD MGI:3030214 ENTREZGENE
NCBI Gene 259027 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1e21 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt B0QZP1 ENTREZGENE
  Q8VGT3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B0QZP1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or1e21  olfactory receptor family 1 subfamily E member 21  Olfr380  olfactory receptor 380  Symbol and/or name change 5135510 APPROVED