Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HDAC10 mRNA | CTD | PMID:20702594 and PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of HDAC10 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of HDAC10 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:20702594 | 2,4-dinitrotoluene | affects expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of HDAC10 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of HDAC10 mRNA | CTD | PMID:21346803 | 3,3'-diindolylmethane | multiple interactions | EXP | | 6480464 | 3 more ... | CTD | PMID:24200994 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HDAC10 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HDAC10 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of HDAC10 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HDAC10 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of HDAC10 gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | HDAC10 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of HDAC10 gene | CTD | PMID:31601247 | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of HDAC10 mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | increases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of HDAC10 mRNA | CTD | PMID:22504374 and PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of HDAC10 mRNA | CTD | PMID:30047161 | allethrin | multiple interactions | ISO | Hdac10 (Rattus norvegicus) | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC10 mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HDAC10 mRNA | CTD | PMID:33051911 more ... | amitrole | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of HDAC10 mRNA | CTD | PMID:30047161 | amphetamine | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of HDAC10 mRNA | CTD | PMID:30779732 | arsenous acid | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of HDAC10 mRNA | CTD | PMID:35676786 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of HDAC10 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | HDAC10 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HDAC10 promoter | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of HDAC10 mRNA | CTD | PMID:25181051 more ... | bisphenol A | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HDAC10 mRNA | CTD | PMID:28628672 | bisphenol A | increases methylation | ISO | Hdac10 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of HDAC10 gene | CTD | PMID:28505145 | bisphenol F | decreases expression | EXP | | 6480464 | bisphenol F results in decreased expression of HDAC10 mRNA | CTD | PMID:30951980 | bortezomib | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of HDAC10 mRNA | CTD | PMID:20977926 | butanal | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of HDAC10 mRNA | CTD | PMID:26079696 | CGP 52608 | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to HDAC10 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of HDAC10 mRNA | CTD | PMID:37019170 | clofibric acid | multiple interactions | ISO | Hdac10 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HDAC10 mRNA | CTD | PMID:17602206 | cobalt dichloride | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of HDAC10 mRNA | CTD | PMID:24386269 | cocaine | affects expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Cocaine affects the expression of HDAC10 mRNA | CTD | PMID:20187946 | cyhalothrin | multiple interactions | ISO | Hdac10 (Rattus norvegicus) | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC10 mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HDAC10 mRNA | CTD | PMID:33051911 more ... | cypermethrin | multiple interactions | ISO | Hdac10 (Rattus norvegicus) | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC10 mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HDAC10 mRNA | CTD | PMID:33051911 more ... | decabromodiphenyl ether | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in decreased expression of HDAC10 mRNA | CTD | PMID:23914054 | dexamethasone | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HDAC10 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HDAC10 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of HDAC10 mRNA | CTD | PMID:35676786 | diethylstilbestrol | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of HDAC10 mRNA | CTD | PMID:32088792 | fenvalerate | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | fenvalerate results in decreased expression of HDAC10 mRNA | CTD | PMID:30307764 | fenvalerate | multiple interactions | ISO | Hdac10 (Rattus norvegicus) | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC10 mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HDAC10 mRNA | CTD | PMID:33051911 more ... | hydrazine | decreases expression | EXP | | 6480464 | hydrazine results in decreased expression of HDAC10 mRNA | CTD | PMID:15282401 | hypochlorous acid | decreases expression | EXP | | 6480464 | Hypochlorous Acid results in decreased expression of HDAC10 mRNA | CTD | PMID:19376150 | indometacin | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HDAC10 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of HDAC10 mRNA | CTD | PMID:28628672 | lead(0) | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Lead results in decreased expression of HDAC10 mRNA | CTD | PMID:19921347 | levetiracetam | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Levetiracetam results in decreased expression of HDAC10 mRNA | CTD | PMID:20345932 | methamphetamine | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Methamphetamine results in decreased expression of HDAC10 mRNA | CTD | PMID:25452209 | methimazole | increases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of HDAC10 mRNA | CTD | PMID:22504374 | methimazole | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of HDAC10 mRNA | CTD | PMID:30047161 | methotrexate | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of HDAC10 mRNA | CTD | PMID:24449571 | N-nitrosodiethylamine | multiple interactions | ISO | Hdac10 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HDAC10 mRNA | CTD | PMID:17602206 | ozone | multiple interactions | ISO | HDAC10 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of HDAC10 mRNA | CTD | PMID:35430440 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of HDAC10 mRNA | CTD | PMID:17562736 | pentane-2,3-dione | increases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | 2 and 3-pentanedione results in increased expression of HDAC10 mRNA | CTD | PMID:25710175 | phenobarbital | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Phenobarbital results in decreased expression of HDAC10 mRNA | CTD | PMID:30047161 | pyrethrins | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Pyrethrins results in decreased expression of HDAC10 mRNA | CTD | PMID:34896426 | rotenone | increases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Rotenone results in increased expression of HDAC10 mRNA | CTD | PMID:29955902 | sodium arsenite | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of HDAC10 mRNA | CTD | PMID:32844245 | sulfadimethoxine | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of HDAC10 mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of HDAC10 mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of HDAC10 mRNA | CTD | PMID:27396813 | tetraphene | increases expression | EXP | | 6480464 | benz(a)anthracene results in increased expression of HDAC10 mRNA | CTD | PMID:26377693 | thioacetamide | decreases expression | ISO | Hdac10 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of HDAC10 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | titanium dioxide results in increased expression of HDAC10 mRNA | CTD | PMID:33064449 | triclosan | increases expression | ISO | HDAC10 (Homo sapiens) | 6480464 | Triclosan results in increased expression of HDAC10 mRNA | CTD | PMID:30510588 | |