Spopfm3 (speckle-type BTB/POZ protein family member 3) - Rat Genome Database

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Gene: Spopfm3 (speckle-type BTB/POZ protein family member 3) Mus musculus
Analyze
No known orthologs.
Symbol: Spopfm3
Name: speckle-type BTB/POZ protein family member 3
RGD ID: 1620415
MGI Page MGI
Description: Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be active in cytoplasm and nucleus.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: EG383977; Gm5286; predicted gene 5286
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Slmap  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,104,021 - 94,107,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,104,021 - 94,107,109 (+)EnsemblGRCm39 Ensembl
GRCm38394,196,714 - 94,199,827 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,196,714 - 94,199,802 (+)EnsemblGRCm38mm10GRCm38
MGSCv37394,000,636 - 94,003,749 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36394,283,769 - 94,284,854 (+)NCBIMGSCv36mm8
Celera395,616,128 - 95,632,122 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
triptonide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635  


Genomics

Variants

.
Variants in Spopfm3
107 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:90
Interacting mature miRNAs:92
Transcripts:ENSMUST00000159524
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1301398Rapop3_mradiation-induced apoptosis 3 (mouse)Not determined390511217100464137Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000159524   ⟹   ENSMUSP00000125267
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,104,021 - 94,107,109 (+)Ensembl
GRCm38.p6 Ensembl394,196,714 - 94,199,802 (+)Ensembl
Protein Sequences
Ensembl Protein ENSMUSP00000125267.2
Reference Protein Sequences
RefSeq Acc Id: ENSMUSP00000125267   ⟸   ENSMUST00000159524
Protein Domains
BTB   MATH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E0CXI6-F1-model_v2 AlphaFold E0CXI6 1-357 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3644284 AgrOrtholog
Ensembl Genes ENSMUSG00000090268 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000159524.2 UniProtKB/TrEMBL
Gene3D-CATH 6.20.250.50 UniProtKB/TrEMBL
InterPro BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  MATH UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
MGD MGI:3644284 ENTREZGENE
NCBI Gene 383977 ENTREZGENE
PANTHER SPECKLE-TYPE BTB/POZ PROTEIN FAMILY MEMBER 1-RELATED UniProtKB/TrEMBL
  SPECKLE-TYPE POZ PROTEIN UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
PhenoGen Spopfm3 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
  MATH UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
  MATH UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
UniProt E0CXI6_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-20 Spopfm3  speckle-type BTB/POZ protein family member 3  Gm5286  predicted gene 5286  Symbol and/or name change 5135510 APPROVED