Slco1a7 (solute carrier organic anion transporter family, member 1a7) - Rat Genome Database

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Gene: Slco1a7 (solute carrier organic anion transporter family, member 1a7) Mus musculus
Analyze
No known orthologs.
Symbol: Slco1a7 (Ensembl: Gm5724)
Name: solute carrier organic anion transporter family, member 1a7 (Ensembl:predicted gene 5724)
RGD ID: 1620379
MGI Page MGI
Description: Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in bile acid and bile salt transport and sodium-independent organic anion transport. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG435927; Gm5724; Solute carrier organic anion transporter family member 1A4; solute carrier organic anion transporter family member 1A4-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396141,653,422 - 141,723,845 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6141,653,844 - 141,719,536 (-)EnsemblGRCm39 Ensembl
GRCm386141,707,696 - 141,778,119 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6141,708,118 - 141,773,810 (-)EnsemblGRCm38mm10GRCm38
MGSCv376141,657,043 - 141,722,299 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366141,670,928 - 141,731,484 (-)NCBIMGSCv36mm8
Celera6144,770,729 - 144,834,453 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map672.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12904583   PMID:14579113   PMID:21873635   PMID:27449599  


Genomics

Variants

.
Variants in Slco1a7
2613 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:105
Interacting mature miRNAs:106
Transcripts:ENSMUST00000148411
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
1301084Bpq5_mblood pressure QTL 5 (mouse)Not determined6129330484149588044Mouse
4141974Skmw14_mskeletal muscle weight 14 (mouse)Not determined6129330484149588044Mouse
1301686Trmq1_mT cell ratio modifier QTL 1 (mouse)Not determined6129330484149588044Mouse
1301620Insq8_minsulin QTL 8 (mouse)Not determined6129534979149588044Mouse
1558959Eamcd2_mexperimental autoimmune myocarditis 2 (mouse)Not determined6129953954149588044Mouse
14746990Manh61_mmandible shape 61 (mouse)6130156355149588044Mouse
14746999Mancz6_mmandible centroid size 6 (mouse)6130156355149588044Mouse
12879916Shm5_msperm head morphology 5 (mouse)6132266532145601739Mouse
1301820Mop1_mmorphine preference 1 (mouse)Not determined6132578005146330736Mouse
15092053Wegrme2_mweek eight growth rate, maternal effect 2 (mouse)6140445726147201498Mouse
15092061Wfigrme1_mweek five growth rate, maternal effect 1 (mouse)6140445726147201498Mouse
15092045Wngrme2_mweek nine growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092047Wsigrme2_mweek six growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092052Wsegrme2_mweek seven growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092056Mgrme1_mmid growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
15092058Lgrme2_mlate growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092060Wfogrme1_mweek four growth rate, maternal effect 1 (mouse)6140497205147252976Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000148411   ⟹   ENSMUSP00000117177
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6141,653,844 - 141,719,536 (-)Ensembl
GRCm38.p6 Ensembl6141,708,118 - 141,773,810 (-)Ensembl
RefSeq Acc Id: NM_001378682   ⟹   NP_001365611
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396141,653,422 - 141,723,845 (-)NCBI
GRCm386141,707,696 - 141,778,119 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001365611 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000117177
  ENSMUSP00000117177.2
Reference Protein Sequences
RefSeq Acc Id: NP_001365611   ⟸   NM_001378682
- UniProtKB: L7N264 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000117177   ⟸   ENSMUST00000148411
Protein Domains
Kazal-like   Major facilitator superfamily (MFS) profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-L7N264-F1-model_v2 AlphaFold L7N264 1-670 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3643685 AgrOrtholog
Ensembl Genes ENSMUSG00000084927 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000148411 ENTREZGENE
  ENSMUST00000148411.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  OA_transporter UniProtKB/TrEMBL
MGD MGI:3643685 ENTREZGENE
NCBI Gene 435927 ENTREZGENE
PANTHER PTHR11388 UniProtKB/TrEMBL
  SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2 UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/TrEMBL
  OATP UniProtKB/TrEMBL
PhenoGen Slco1a7 PhenoGen
PROSITE KAZAL_2 UniProtKB/TrEMBL
  MFS UniProtKB/TrEMBL
Superfamily-SCOP MFS_gen_substrate_transporter UniProtKB/TrEMBL
  SSF100895 UniProtKB/TrEMBL
UniProt L7N264 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-21 Slco1a7  solute carrier organic anion transporter family, member 1a7  Gm5724  predicted gene 5724  Symbol and/or name updated 27372883 PROVISIONAL