Vmn2r59 (vomeronasal 2, receptor 59) - Rat Genome Database

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Gene: Vmn2r59 (vomeronasal 2, receptor 59) Mus musculus
Analyze
No known orthologs.
Symbol: Vmn2r59
Name: vomeronasal 2, receptor 59
RGD ID: 1619513
MGI Page MGI
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: EG628444; vomeronasal receptor Vmn2r59
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39741,661,216 - 41,708,405 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl741,660,708 - 41,708,447 (-)EnsemblGRCm39 Ensembl
GRCm38742,011,792 - 42,058,981 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl742,011,284 - 42,059,023 (-)EnsemblGRCm38mm10GRCm38
MGSCv37749,267,162 - 49,314,351 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36741,784,945 - 41,820,633 (-)NCBIMGSCv36mm8
Celera737,588,182 - 37,636,487 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:17382427   PMID:21873635  


Genomics

Variants

.
Variants in Vmn2r59
1640 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:37
Interacting mature miRNAs:37
Transcripts:ENSMUST00000168489
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse

Markers in Region
Gprc2a-rs1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7B3UniSTS
Cytogenetic Map7B4UniSTS
cM Map7 UniSTS
cM Map720.0UniSTS
cM Map4 UniSTS
Gprc2a-rs4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A3.2UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map7B3UniSTS
cM Map720.0UniSTS
cM MapUN UniSTS
cM Map7 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001105056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000168489   ⟹   ENSMUSP00000131856
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl741,660,708 - 41,708,447 (-)Ensembl
GRCm38.p6 Ensembl742,011,284 - 42,059,023 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233327   ⟹   ENSMUSP00000156474
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl741,660,708 - 41,708,447 (-)Ensembl
GRCm38.p6 Ensembl742,011,284 - 42,059,023 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233351
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl741,678,481 - 41,708,447 (-)Ensembl
GRCm38.p6 Ensembl742,029,057 - 42,059,023 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233456   ⟹   ENSMUSP00000156689
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl741,678,481 - 41,708,447 (-)Ensembl
GRCm38.p6 Ensembl742,029,057 - 42,059,023 (-)Ensembl
RefSeq Acc Id: NM_001105056   ⟹   NP_001098526
RefSeq Status: INFERRED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39741,661,216 - 41,708,405 (-)NCBI
GRCm38742,011,792 - 42,058,981 (-)ENTREZGENE
MGSCv37749,267,162 - 49,314,351 (-)RGD
Celera737,588,182 - 37,636,487 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001098526 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000131856
  ENSMUSP00000131856.2
  ENSMUSP00000156474.2
  ENSMUSP00000156689.2
Reference Protein Sequences
RefSeq Acc Id: NP_001098526   ⟸   NM_001105056
- Peptide Label: precursor
- UniProtKB: E9PUT5 (UniProtKB/TrEMBL),   E9Q5Z2 (UniProtKB/TrEMBL),   E9PVG6 (UniProtKB/TrEMBL),   E9Q4U2 (UniProtKB/TrEMBL),   E9Q5S1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000156689   ⟸   ENSMUST00000233456
RefSeq Acc Id: ENSMUSP00000156474   ⟸   ENSMUST00000233327
RefSeq Acc Id: ENSMUSP00000131856   ⟸   ENSMUST00000168489
Protein Domains
G-protein coupled receptors family 3 profile   GPCR family 3 nine cysteines   Receptor ligand binding region

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PUT5-F1-model_v2 AlphaFold E9PUT5 1-865 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3643747 AgrOrtholog
Ensembl Genes ENSMUSG00000092032 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000168489 ENTREZGENE
  ENSMUST00000168489.3 UniProtKB/TrEMBL
  ENSMUST00000233327.2 UniProtKB/TrEMBL
  ENSMUST00000233456.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report mmu:628444 UniProtKB/TrEMBL
MGD MGI:3643747 ENTREZGENE
NCBI Gene 628444 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 57-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vmn2r59 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A3B2WCE4_MOUSE UniProtKB/TrEMBL
  A0A3B2WCU2_MOUSE UniProtKB/TrEMBL
  E9PUT5 ENTREZGENE, UniProtKB/TrEMBL
  E9PVG6 ENTREZGENE
  E9Q4U2 ENTREZGENE
  E9Q5S1 ENTREZGENE
  E9Q5Z2 ENTREZGENE
UniProt Secondary E9PVG6 UniProtKB/TrEMBL
  E9Q4U2 UniProtKB/TrEMBL
  E9Q5S1 UniProtKB/TrEMBL
  E9Q5Z2 UniProtKB/TrEMBL