Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of D16ERTD472E mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of D16ERTD472E mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of C21ORF91 mRNA | CTD | PMID:30165855 | 17beta-estradiol | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Estradiol results in increased expression of C21ORF91 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:27291303 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of C11H21ORF91 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of C11H21ORF91 mRNA | CTD | PMID:32109520 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of D16ERTD472E mRNA | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | decreases expression | EXP | | 6480464 | bisphenol S results in decreased expression of D16ERTD472E mRNA | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of D16ERTD472E gene | CTD | PMID:31683443 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of C21ORF91 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of C11H21ORF91 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of C11H21ORF91 mRNA | CTD | PMID:28959563 | aflatoxin B1 | affects expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of C21ORF91 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of C21ORF91 mRNA | CTD | PMID:22100608 | aflatoxin M1 | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of C21ORF91 mRNA | CTD | PMID:30928695 | amiodarone | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of C21ORF91 mRNA | CTD | PMID:19774075 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of D16ERTD472E mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of C21ORF91 mRNA | CTD | PMID:20064835 more ... | benzo[a]pyrene diol epoxide I | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of D16ERTD472E mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of C11H21ORF91 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of D16ERTD472E mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of C11H21ORF91 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | affects expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of C21ORF91 mRNA | CTD | PMID:25181051 | cadmium dichloride | decreases methylation | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of C11H21ORF91 promoter | CTD | PMID:22457795 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of D16ERTD472E mRNA | CTD | PMID:25554681 | cisplatin | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of C21ORF91 mRNA | CTD | PMID:19561079 | cisplatin | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of C21ORF91 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of C11H21ORF91 mRNA | CTD | PMID:24386269 | copper atom | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of C21ORF91 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of C21ORF91 mRNA | CTD | PMID:20971185 | Cuprizon | decreases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of C11H21ORF91 mRNA | CTD | PMID:27523638 | cyclosporin A | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of C21ORF91 mRNA | CTD | PMID:20106945 | dicrotophos | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of C21ORF91 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of C11H21ORF91 mRNA | CTD | PMID:33729688 | doxorubicin | affects expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of C21ORF91 mRNA | CTD | PMID:25529476 | doxorubicin | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of C21ORF91 mRNA | CTD | PMID:29803840 | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of D16ERTD472E mRNA | CTD | PMID:28329830 | formaldehyde | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of C21ORF91 mRNA | CTD | PMID:20655997 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of D16ERTD472E mRNA | CTD | PMID:25270620 | methyl methanesulfonate | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of C21ORF91 mRNA | CTD | PMID:23649840 | N,N-diethyl-m-toluamide | multiple interactions | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of C11H21ORF91 gene | CTD | PMID:33148267 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of D16ERTD472E mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of C11H21ORF91 mRNA | CTD | PMID:33387578 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of D16ERTD472E mRNA | CTD | PMID:23892564 | permethrin | multiple interactions | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of C11H21ORF91 gene | CTD | PMID:33148267 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of D16ERTD472E mRNA | CTD | PMID:23091169 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of D16ERTD472E mRNA | CTD | PMID:18301758 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of D16ERTD472E mRNA | CTD | PMID:23811191 | potassium chromate | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of C21ORF91 mRNA | CTD | PMID:22714537 | resveratrol | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of C21ORF91 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of C11H21ORF91 mRNA | CTD | PMID:28374803 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of D16ERTD472E mRNA | CTD | PMID:19073995 | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of D16ERTD472E mRNA | CTD | PMID:21795629 | thioacetamide | increases expression | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of C11H21ORF91 mRNA | CTD | PMID:34492290 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of D16ERTD472E mRNA | CTD | PMID:32835833 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of D16ERTD472E mRNA | CTD | PMID:35537566 | urethane | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Urethane results in increased expression of C21ORF91 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of C21ORF91 mRNA | CTD | PMID:23179753 | valproic acid | increases expression | ISO | C21orf91 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of C21ORF91 mRNA | CTD | PMID:29154799 | vinclozolin | increases methylation | ISO | C11h21orf91 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of C11H21ORF91 promoter | CTD | PMID:22570695 | zinc atom | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of C21ORF91 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | C21orf91 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of C21ORF91 mRNA | CTD | PMID:18593933 | |