Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of ATG16L2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ATG16L2 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of ATG16L2 mRNA | CTD | PMID:30723492 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATG16L2 mRNA | CTD | PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATG16L2 mRNA | CTD | PMID:33387578 | 6-propyl-2-thiouracil | decreases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ATG16L2 mRNA | CTD | PMID:30047161 | acetamide | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of ATG16L2 mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | ATG16L2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATG16L2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATG16L2 mRNA | CTD | PMID:32699268 | acrylamide | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ATG16L2 mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ATG16L2 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ATG16L2 mRNA | CTD | PMID:21632981 and PMID:21641981 | all-trans-retinoic acid | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ATG16L2 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | ATG16L2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATG16L2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATG16L2 mRNA | CTD | PMID:32699268 | amitrole | decreases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of ATG16L2 mRNA | CTD | PMID:30047161 | amosite asbestos | increases methylation | ISO | ATG16L2 (Homo sapiens) | 6480464 | Asbestos and Amosite results in increased methylation of ATG16L2 promoter | CTD | PMID:29626692 | aristolochic acid A | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ATG16L2 mRNA | CTD | PMID:33212167 | atrazine | multiple interactions | EXP | | 6480464 | Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] | CTD | PMID:30360616 | atrazine | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Atrazine results in increased expression of ATG16L2 mRNA | CTD | PMID:36841081 | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of ATG16L2 mRNA | CTD | PMID:30360616 | benzo[a]pyrene | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ATG16L2 mRNA | CTD | PMID:21632981 and PMID:22316170 | benzo[a]pyrene | increases methylation | ISO | ATG16L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ATG16L2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ATG16L2 mRNA | CTD | PMID:19770486 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ATG16L2 mRNA | CTD | PMID:31163220 | bisphenol A | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ATG16L2 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ATG16L2 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ATG16L2 mRNA | CTD | PMID:30816183 and PMID:32528016 | butanal | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ATG16L2 mRNA | CTD | PMID:26079696 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of ATG16L2 mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | cisplatin | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ATG16L2 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | ATG16L2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ATG16L2 mRNA | CTD | PMID:27392435 | copper(II) sulfate | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ATG16L2 mRNA | CTD | PMID:19549813 | cyproconazole | increases expression | EXP | | 6480464 | cyproconazole results in increased expression of ATG16L2 mRNA | CTD | PMID:22334560 | dibutyl phthalate | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of ATG16L2 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of ATG16L2 mRNA | CTD | PMID:28302478 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of ATG16L2 mRNA | CTD | PMID:22334560 and PMID:35436446 | ethyl methanesulfonate | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of ATG16L2 mRNA | CTD | PMID:23649840 | gentamycin | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of ATG16L2 mRNA | CTD | PMID:33387578 | glafenine | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of ATG16L2 mRNA | CTD | PMID:24136188 | leflunomide | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | leflunomide results in increased expression of ATG16L2 mRNA | CTD | PMID:24136188 | leflunomide | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of ATG16L2 mRNA | CTD | PMID:28988120 | lycopene | multiple interactions | EXP | | 6480464 | Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] | CTD | PMID:30360616 | maneb | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ATG16L2 mRNA | CTD | PMID:36117858 | methimazole | decreases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of ATG16L2 mRNA | CTD | PMID:30047161 | methotrexate | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of ATG16L2 mRNA | CTD | PMID:21678067 | N-acetyl-L-cysteine | multiple interactions | ISO | ATG16L2 (Homo sapiens) | 6480464 | Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG16L2 mRNA] | CTD | PMID:33146789 | nitrofen | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | nitrofen results in increased expression of ATG16L2 mRNA | CTD | PMID:26720608 | ozone | multiple interactions | ISO | ATG16L2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATG16L2 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ATG16L2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ATG16L2 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ATG16L2 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of ATG16L2 mRNA | CTD | PMID:33387578 | paraquat | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ATG16L2 mRNA | CTD | PMID:36117858 | pentanal | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | pentanal results in decreased expression of ATG16L2 mRNA | CTD | PMID:26079696 | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of ATG16L2 mRNA | CTD | PMID:37995155 | phenobarbital | multiple interactions | EXP | | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ATG16L2 mRNA] | CTD | PMID:19482888 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of ATG16L2 mRNA | CTD | PMID:19482888 | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of ATG16L2 mRNA | CTD | PMID:22334560 and PMID:23970803 | quercetin | increases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ATG16L2 mRNA | CTD | PMID:21632981 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of ATG16L2 mRNA | CTD | PMID:23221170 | sulfadimethoxine | decreases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of ATG16L2 mRNA | CTD | PMID:30047161 | testosterone | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of ATG16L2 mRNA | CTD | PMID:33359661 | tetrachloromethane | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of ATG16L2 mRNA | CTD | PMID:31150632 | tetraphene | affects expression | EXP | | 6480464 | benz(a)anthracene affects the expression of ATG16L2 mRNA | CTD | PMID:26377693 | thioacetamide | decreases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ATG16L2 mRNA | CTD | PMID:34492290 | triadimefon | increases expression | EXP | | 6480464 | triadimefon results in increased expression of ATG16L2 mRNA | CTD | PMID:23970803 | trichloroethene | increases expression | ISO | Atg16l2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of ATG16L2 mRNA | CTD | PMID:33387578 | trovafloxacin | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | trovafloxacin results in decreased expression of ATG16L2 mRNA | CTD | PMID:33609687 | urethane | decreases expression | ISO | ATG16L2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of ATG16L2 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ATG16L2 mRNA | CTD | PMID:17963808 | |