Fam131c (family with sequence similarity 131, member C) - Rat Genome Database

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Gene: Fam131c (family with sequence similarity 131, member C) Mus musculus
Analyze
Symbol: Fam131c
Name: family with sequence similarity 131, member C
RGD ID: 1617243
MGI Page MGI
Description: Orthologous to human FAM131C (family with sequence similarity 131 member C).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm693; hypothetical protein LOC277743; uncharacterized protein LOC277743
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,095,503 - 141,111,485 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,095,531 - 141,111,486 (+)EnsemblGRCm39 Ensembl
GRCm384141,368,192 - 141,384,174 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,368,220 - 141,384,175 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,924,135 - 140,940,090 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,640,329 - 140,656,250 (+)NCBIMGSCv36mm8
Celera4143,185,056 - 143,201,002 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:21677750  


Genomics

Comparative Map Data
Fam131c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,095,503 - 141,111,485 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,095,531 - 141,111,486 (+)EnsemblGRCm39 Ensembl
GRCm384141,368,192 - 141,384,174 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,368,220 - 141,384,175 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,924,135 - 140,940,090 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,640,329 - 140,656,250 (+)NCBIMGSCv36mm8
Celera4143,185,056 - 143,201,002 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.88NCBI
FAM131C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,057,769 - 16,073,651 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,057,769 - 16,073,651 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,384,264 - 16,400,146 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,256,851 - 16,272,714 (-)NCBINCBI36Build 36hg18NCBI36
Celera114,864,163 - 14,877,593 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef114,902,743 - 14,918,526 (-)NCBIHuRef
CHM1_1116,182,877 - 16,198,717 (-)NCBICHM1_1
T2T-CHM13v2.0115,499,150 - 15,515,031 (-)NCBIT2T-CHM13v2.0
Fam131c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,957,444 - 158,973,773 (+)NCBIGRCr8
mRatBN7.25153,674,459 - 153,690,791 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,671,772 - 153,690,800 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05159,914,931 - 159,931,089 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,914,931 - 159,931,090 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,642,663 - 163,647,669 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,268,665 - 160,273,424 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5152,046,363 - 152,054,951 (+)NCBICelera
Cytogenetic Map5q36NCBI
Fam131c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,182,570 - 2,207,068 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555272,182,624 - 2,203,063 (+)NCBIChiLan1.0ChiLan1.0
FAM131C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,847,450 - 210,863,352 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,096,061 - 210,111,951 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,195,111 - 15,211,000 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,188,630 - 16,199,722 (-)NCBIpanpan1.1PanPan1.1panPan2
FAM131C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,595,383 - 81,611,739 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,595,276 - 81,611,112 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,114,619 - 78,147,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0282,224,690 - 82,257,357 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,240,352 - 82,257,578 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,977,767 - 79,010,545 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,994,895 - 80,027,712 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,062,856 - 81,095,406 (+)NCBIUU_Cfam_GSD_1.0
Fam131c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,777,546 - 37,782,672 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,602,881 - 3,607,452 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,602,330 - 3,607,462 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM131C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,193,399 - 75,212,154 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,193,397 - 75,213,081 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,529,608 - 69,545,541 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225533
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,223,237 - 116,241,144 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20116,235,177 - 116,241,379 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605419,719,909 - 19,767,949 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam131c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,212,404 - 2,233,574 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,212,511 - 2,234,012 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fam131c
609 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:302
Count of miRNA genes:240
Interacting mature miRNAs:265
Transcripts:ENSMUST00000006380
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1357534Cinda3_mcytokine induced activation 3 (mouse)Not determined4137617848142289472Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000006380   ⟹   ENSMUSP00000006380
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4141,095,531 - 141,111,486 (+)Ensembl
GRCm38.p6 Ensembl4141,368,220 - 141,384,175 (+)Ensembl
RefSeq Acc Id: NM_001085513   ⟹   NP_001078982
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394141,095,503 - 141,111,485 (+)NCBI
GRCm384141,368,192 - 141,384,174 (+)NCBI
MGSCv374140,924,135 - 140,940,090 (+)RGD
Celera4143,185,028 - 143,201,001 (+)NCBI
cM Map4 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001078982 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI47049 (Get FASTA)   NCBI Sequence Viewer  
  AAI47050 (Get FASTA)   NCBI Sequence Viewer  
  EDL13363 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000006380
  ENSMUSP00000006380.5
RefSeq Acc Id: NP_001078982   ⟸   NM_001085513
- UniProtKB: A2ADB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000006380   ⟸   ENSMUST00000006380

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2ADB2-F1-model_v2 AlphaFold A2ADB2 1-273 view protein structure

Promoters
RGD ID:6835293
Promoter ID:MM_KWN:40476
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:NM_001085513
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,923,726 - 140,924,226 (+)MPROMDB
RGD ID:6885302
Promoter ID:EPDNEW_M6102
Type:multiple initiation site
Name:Fam131c_1
Description:Mus musculus family with sequence similarity 131, member C ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384141,368,153 - 141,368,213EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685539 AgrOrtholog
Ensembl Genes ENSMUSG00000006218 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000006380 ENTREZGENE
  ENSMUST00000006380.5 UniProtKB/TrEMBL
InterPro FAM131 UniProtKB/TrEMBL
KEGG Report mmu:277743 UniProtKB/TrEMBL
MGD MGI:2685539 ENTREZGENE
NCBI Gene 277743 ENTREZGENE
PANTHER PROTEIN FAM131C UniProtKB/TrEMBL
  PTHR15736 UniProtKB/TrEMBL
Pfam FAM131 UniProtKB/TrEMBL
PhenoGen Fam131c PhenoGen
UniProt A2ADB2 ENTREZGENE, UniProtKB/TrEMBL