Or5bw2 (olfactory receptor family 5 subfamily BW member 2) - Rat Genome Database

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Gene: Or5bw2 (olfactory receptor family 5 subfamily BW member 2) Mus musculus
Analyze
No known orthologs.
Symbol: Or5bw2
Name: olfactory receptor family 5 subfamily BW member 2
RGD ID: 1616482
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Is expressed in olfactory epithelium.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2QGBW-3300391-3301317; MGC123533; MOR222; MOR222-3; olfactory receptor 1350; olfactory receptor MOR222-3; Olfr1350
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3976,572,992 - 6,573,918 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl76,567,840 - 6,574,400 (+)EnsemblGRCm39 Ensembl
GRCm3876,569,993 - 6,570,919 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl76,564,841 - 6,571,401 (+)EnsemblGRCm38mm10GRCm38
MGSCv3776,522,704 - 6,523,630 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3676,174,079 - 6,175,005 (+)NCBIMGSCv36mm8
Celera76,300,391 - 6,301,317 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map73.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21267068   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or5bw2
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:72
Interacting mature miRNAs:74
Transcripts:ENSMUST00000070985
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1302115Abhr3_mallergen-induced bronchial hyperresponsiveness 3 (mouse)Not determined7331599616637423Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25394569Skmw57_mskeletal muscle weight 57, gastroc (mouse)7458046916687861Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse

Markers in Region
UniSTS:485085  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3876,569,993 - 6,570,919UniSTSGRCm38
MGSCv3776,522,704 - 6,523,630UniSTSGRCm37
Celera76,300,391 - 6,301,317UniSTS
Cytogenetic Map7A1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000070985   ⟹   ENSMUSP00000069927
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl76,572,992 - 6,573,918 (+)Ensembl
GRCm38.p6 Ensembl76,569,993 - 6,570,919 (+)Ensembl
RefSeq Acc Id: ENSMUST00000207221   ⟹   ENSMUSP00000146486
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl76,567,840 - 6,574,400 (+)Ensembl
GRCm38.p6 Ensembl76,564,841 - 6,571,401 (+)Ensembl
RefSeq Acc Id: ENSMUST00000219278   ⟹   ENSMUSP00000151318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl76,567,840 - 6,574,400 (+)Ensembl
GRCm38.p6 Ensembl76,564,841 - 6,571,401 (+)Ensembl
RefSeq Acc Id: NM_146389   ⟹   NP_666501
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3976,572,992 - 6,573,918 (+)NCBI
GRCm3876,569,993 - 6,570,919 (+)ENTREZGENE
MGSCv3776,522,704 - 6,523,630 (+)RGD
Celera76,300,391 - 6,301,317 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_666501 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI04064 (Get FASTA)   NCBI Sequence Viewer  
  AAL61369 (Get FASTA)   NCBI Sequence Viewer  
  AAP71733 (Get FASTA)   NCBI Sequence Viewer  
  EDL31323 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000069927
  ENSMUSP00000069927.4
  ENSMUSP00000146486.2
  ENSMUSP00000151318.2
Reference Protein Sequences
RefSeq Acc Id: NP_666501   ⟸   NM_146389
- UniProtKB: Q8VF34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000069927   ⟸   ENSMUST00000070985
RefSeq Acc Id: ENSMUSP00000151318   ⟸   ENSMUST00000219278
RefSeq Acc Id: ENSMUSP00000146486   ⟸   ENSMUST00000207221
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VF34-F1-model_v2 AlphaFold Q8VF34 1-308 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3031184 AgrOrtholog
Ensembl Genes ENSMUSG00000056696 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070985 ENTREZGENE
  ENSMUST00000070985.4 UniProtKB/TrEMBL
  ENSMUST00000207221.3 UniProtKB/TrEMBL
  ENSMUST00000219278.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258384 UniProtKB/TrEMBL
MGD MGI:3031184 ENTREZGENE
NCBI Gene 258384 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5bw2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VF34 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5bw2  olfactory receptor family 5 subfamily BW member 2  Olfr1350  olfactory receptor 1350  Symbol and/or name change 5135510 APPROVED