Rundc3b (RUN domain containing 3B) - Rat Genome Database

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Gene: Rundc3b (RUN domain containing 3B) Mus musculus
Analyze
Symbol: Rundc3b
Name: RUN domain containing 3B
RGD ID: 1615644
MGI Page MGI
Description: Orthologous to human RUNDC3B (RUN domain containing 3B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm440; MGC68340; RUN domain-containing protein 3B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3958,540,336 - 8,673,079 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl58,540,334 - 8,672,952 (-)EnsemblGRCm39 Ensembl
GRCm3858,490,336 - 8,623,084 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,490,334 - 8,622,952 (-)EnsemblGRCm38mm10GRCm38
MGSCv3758,490,336 - 8,622,952 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3658,496,342 - 8,628,958 (-)NCBIMGSCv36mm8
Celera58,410,690 - 8,543,386 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21677750   PMID:32560809  


Genomics

Comparative Map Data
Rundc3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3958,540,336 - 8,673,079 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl58,540,334 - 8,672,952 (-)EnsemblGRCm39 Ensembl
GRCm3858,490,336 - 8,623,084 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,490,334 - 8,622,952 (-)EnsemblGRCm38mm10GRCm38
MGSCv3758,490,336 - 8,622,952 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3658,496,342 - 8,628,958 (-)NCBIMGSCv36mm8
Celera58,410,690 - 8,543,386 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.43NCBI
RUNDC3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38787,628,398 - 87,832,296 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl787,627,548 - 87,832,296 (+)EnsemblGRCh38hg38GRCh38
GRCh37787,257,714 - 87,461,611 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36787,095,665 - 87,297,691 (+)NCBINCBI36Build 36hg18NCBI36
Celera781,962,343 - 82,166,173 (+)NCBICelera
Cytogenetic Map7q21.12NCBI
HuRef781,867,579 - 82,071,542 (+)NCBIHuRef
CHM1_1787,187,835 - 87,391,791 (+)NCBICHM1_1
T2T-CHM13v2.0788,878,278 - 89,082,221 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2786,589,043 - 86,792,931 (+)NCBI
Rundc3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8426,417,501 - 26,554,404 (+)NCBIGRCr8
mRatBN7.2425,462,543 - 25,599,477 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl425,462,752 - 25,599,471 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx430,458,137 - 30,587,351 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0426,384,375 - 26,513,583 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0424,758,304 - 24,887,472 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0422,443,727 - 22,589,526 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,445,414 - 22,586,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,380,390 - 22,518,353 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4421,546,162 - 21,689,813 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera420,954,615 - 21,085,289 (+)NCBICelera
Cytogenetic Map4q12NCBI
Rundc3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554325,032,468 - 5,186,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554325,032,468 - 5,186,402 (+)NCBIChiLan1.0ChiLan1.0
RUNDC3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26105,505,965 - 105,713,961 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17153,770,603 - 153,978,599 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0779,621,222 - 79,829,021 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1793,270,709 - 93,477,463 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl793,270,747 - 93,477,463 (+)Ensemblpanpan1.1panPan2
RUNDC3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11413,764,583 - 13,932,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1413,803,576 - 14,019,704 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1413,356,985 - 13,504,772 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01413,549,867 - 13,697,960 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1413,549,867 - 13,697,578 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11413,733,175 - 13,901,620 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01413,458,776 - 13,627,233 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01413,742,371 - 13,911,298 (+)NCBIUU_Cfam_GSD_1.0
Rundc3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511826,887,399 - 26,939,764 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367631,052,778 - 1,193,629 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367631,052,229 - 1,193,908 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUNDC3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl992,528,662 - 92,823,561 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1992,525,589 - 92,823,574 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29101,967,854 - 102,119,244 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RUNDC3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12161,119,131 - 61,296,687 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2161,121,388 - 61,296,800 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604242,773,392 - 42,956,392 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rundc3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248095,560,661 - 5,741,546 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248095,565,197 - 5,741,425 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rundc3b
3298 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:589
Count of miRNA genes:412
Interacting mature miRNAs:463
Transcripts:ENSMUST00000047485, ENSMUST00000115378
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141234Pbwg14_mpostnatal body weight growth 14 (mouse)Not determined5121273552Mouse
1301468Eye1_meye weight 1 (mouse)Not determined5121929650Mouse
10412081Bwq13_mbody weight QTL 13 (mouse)Not determined5123606323Mouse
12904958Gmmq8_mgastrocnemius muscle mass QTL 8 (mouse)5129421124Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
12738412Lfibq4_mliver fibrosis QTL 4 (mouse)5315000020799180Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
13442491Mecth1_mmechanosensation threshold 1 (mouse)5451800019834998Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000047485   ⟹   ENSMUSP00000040108
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl58,540,334 - 8,672,952 (-)Ensembl
GRCm38.p6 Ensembl58,490,334 - 8,622,952 (-)Ensembl
RefSeq Acc Id: ENSMUST00000115378   ⟹   ENSMUSP00000111036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl58,542,267 - 8,672,952 (-)Ensembl
GRCm38.p6 Ensembl58,492,267 - 8,622,952 (-)Ensembl
RefSeq Acc Id: NM_001347311   ⟹   NP_001334240
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3958,540,336 - 8,672,952 (-)NCBI
GRCm3858,490,336 - 8,622,952 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359961   ⟹   NP_001346890
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3958,540,336 - 8,672,952 (-)NCBI
GRCm3858,490,336 - 8,622,952 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198620   ⟹   NP_941022
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3958,540,336 - 8,672,952 (-)NCBI
GRCm3858,490,336 - 8,622,952 (-)NCBI
MGSCv3758,490,336 - 8,622,952 (-)RGD
Celera58,410,690 - 8,543,386 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006503578   ⟹   XP_006503641
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3958,540,336 - 8,673,079 (-)NCBI
GRCm3858,490,336 - 8,623,084 (-)NCBI
Sequence:
RefSeq Acc Id: NP_941022   ⟸   NM_198620
- Peptide Label: isoform 2
- UniProtKB: Q6PFX5 (UniProtKB/Swiss-Prot),   Q6PDC0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006503641   ⟸   XM_006503578
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001346890   ⟸   NM_001359961
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001334240   ⟸   NM_001347311
- Peptide Label: isoform 1
- UniProtKB: D3YUQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000040108   ⟸   ENSMUST00000047485
RefSeq Acc Id: ENSMUSP00000111036   ⟸   ENSMUST00000115378
Protein Domains
RUN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6PDC0-F1-model_v2 AlphaFold Q6PDC0 1-408 view protein structure

Promoters
RGD ID:6838276
Promoter ID:MM_KWN:41333
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000115378,   OTTMUST00000055842
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3658,622,361 - 8,622,861 (-)MPROMDB
RGD ID:6885960
Promoter ID:EPDNEW_M6431
Type:initiation region
Name:Rundc3b_1
Description:Mus musculus RUN domain containing 3B , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3858,623,017 - 8,623,077EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685286 AgrOrtholog
Ensembl Genes ENSMUSG00000040570 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047485 ENTREZGENE
  ENSMUST00000047485.15 UniProtKB/Swiss-Prot
  ENSMUST00000115378 ENTREZGENE
  ENSMUST00000115378.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.900 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Run_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUN_RUNDC3B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUNDC3A_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:242819 UniProtKB/Swiss-Prot
MGD MGI:2685286 ENTREZGENE
NCBI Gene 242819 ENTREZGENE
PANTHER RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RUN DOMAIN-CONTAINING PROTEIN 3B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rundc3b PhenoGen
PROSITE RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3YUQ5 ENTREZGENE, UniProtKB/TrEMBL
  Q6PDC0 ENTREZGENE
  Q6PFX5 ENTREZGENE
  RUN3B_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6PFX5 UniProtKB/Swiss-Prot