Or5ae2 (olfactory receptor family 5 subfamily AE member 2) - Rat Genome Database

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Gene: Or5ae2 (olfactory receptor family 5 subfamily AE member 2) Mus musculus
Analyze
Symbol: Or5ae2
Name: olfactory receptor family 5 subfamily AE member 2
RGD ID: 1615616
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2NHDJ-11231385-11230438; MOR254; MOR254-2; olfactory receptor 291; olfactory receptor MOR254-2; Olfr291
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39784,502,779 - 84,506,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl784,502,761 - 84,508,820 (+)EnsemblGRCm39 Ensembl
GRCm38784,853,571 - 84,857,318 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl784,853,553 - 84,859,612 (+)EnsemblGRCm38mm10GRCm38
MGSCv37792,002,081 - 92,005,828 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36784,732,550 - 84,733,503 (+)NCBIMGSCv36mm8
Celera782,256,691 - 82,260,439 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (ISA)

Molecular Function

References
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or5ae2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39784,502,779 - 84,506,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl784,502,761 - 84,508,820 (+)EnsemblGRCm39 Ensembl
GRCm38784,853,571 - 84,857,318 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl784,853,553 - 84,859,612 (+)EnsemblGRCm38mm10GRCm38
MGSCv37792,002,081 - 92,005,828 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36784,732,550 - 84,733,503 (+)NCBIMGSCv36mm8
Celera782,256,691 - 82,260,439 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.38NCBI
Or5ae2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,213,872 - 148,214,819 (+)NCBIGRCr8
mRatBN7.21138,804,766 - 138,805,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1138,801,953 - 138,807,998 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01512,219,307 - 12,220,261 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Cytogenetic Map1q31NCBI

Variants

.
Variants in Or5ae2
150 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSMUST00000078172
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse

Markers in Region
UniSTS:485090  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38784,856,365 - 84,857,318UniSTSGRCm38
MGSCv37792,004,875 - 92,005,828UniSTSGRCm37
Celera782,259,486 - 82,260,439UniSTS
Cytogenetic Map7E1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000211582   ⟹   ENSMUSP00000148266
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl784,502,779 - 84,506,526 (+)Ensembl
GRCm38.p6 Ensembl784,853,571 - 84,857,318 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217039   ⟹   ENSMUSP00000150934
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl784,502,761 - 84,508,820 (+)Ensembl
GRCm38.p6 Ensembl784,853,553 - 84,859,612 (+)Ensembl
RefSeq Acc Id: NM_146415   ⟹   NP_666527
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39784,502,779 - 84,506,526 (+)NCBI
GRCm38784,853,571 - 84,857,318 (+)ENTREZGENE
MGSCv37792,002,081 - 92,005,828 (+)RGD
Celera782,256,691 - 82,260,439 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_666527   ⟸   NM_146415
- UniProtKB: Q8VF60 (UniProtKB/TrEMBL),   Q496V7 (UniProtKB/TrEMBL),   Q7TS12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000150934   ⟸   ENSMUST00000217039
RefSeq Acc Id: ENSMUSP00000148266   ⟸   ENSMUST00000211582
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000070460 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000211582 ENTREZGENE
  ENSMUST00000211582.2 UniProtKB/TrEMBL
  ENSMUST00000217039.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258410 UniProtKB/TrEMBL
MGD MGI:3030125 ENTREZGENE
NCBI Gene 258410 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5ae2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A4FUJ0_MOUSE UniProtKB/TrEMBL
  Q496V7 ENTREZGENE, UniProtKB/TrEMBL
  Q7TS12 ENTREZGENE, UniProtKB/TrEMBL
  Q8VF60 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5ae2  olfactory receptor family 5 subfamily AE member 2  Olfr291  olfactory receptor 291  Symbol and/or name change 5135510 APPROVED