Or5ae1 (olfactory receptor family 5 subfamily AE member 1) - Rat Genome Database

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Gene: Or5ae1 (olfactory receptor family 5 subfamily AE member 1) Mus musculus
Analyze
Symbol: Or5ae1
Name: olfactory receptor family 5 subfamily AE member 1
RGD ID: 1615615
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2NHDJ-11170115-11169168; MGC157560; MOR254; MOR254-1; olfactory receptor 290; olfactory receptor MOR254-1; Olfr290
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39784,564,989 - 84,565,936 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl784,564,989 - 84,565,936 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl784,562,283 - 84,570,069 (+)EnsemblGRCm39 Ensembl
GRCm38784,915,781 - 84,916,728 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl784,913,075 - 84,920,861 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl784,915,781 - 84,916,728 (+)EnsemblGRCm38mm10GRCm38
MGSCv37792,064,291 - 92,065,238 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36784,791,966 - 84,792,913 (+)NCBIMGSCv36mm8
Celera782,320,762 - 82,321,709 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or5ae1
33 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:47
Interacting mature miRNAs:47
Transcripts:ENSMUST00000073468
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse

Markers in Region
UniSTS:491631  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38784,915,689 - 84,916,793UniSTSGRCm38
MGSCv37792,064,199 - 92,065,303UniSTSGRCm37
Celera782,320,670 - 82,321,774UniSTS
Cytogenetic Map7E1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000073468   ⟹   ENSMUSP00000073172
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl784,564,989 - 84,565,936 (+)Ensembl
GRCm38.p6 Ensembl784,915,781 - 84,916,728 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214501   ⟹   ENSMUSP00000149411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl784,562,297 - 84,570,069 (+)Ensembl
GRCm38.p6 Ensembl784,913,089 - 84,920,861 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216184   ⟹   ENSMUSP00000149113
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl784,562,283 - 84,570,069 (+)Ensembl
GRCm38.p6 Ensembl784,913,075 - 84,920,861 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216367   ⟹   ENSMUSP00000149523
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl784,562,283 - 84,570,069 (+)Ensembl
GRCm38.p6 Ensembl784,913,075 - 84,920,861 (+)Ensembl
RefSeq Acc Id: NM_146416   ⟹   NP_666528
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39784,564,989 - 84,565,936 (+)NCBI
GRCm38784,915,781 - 84,916,728 (+)ENTREZGENE
MGSCv37792,064,291 - 92,065,238 (+)RGD
Celera782,320,762 - 82,321,709 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_666528   ⟸   NM_146416
- UniProtKB: Q7TS13 (UniProtKB/TrEMBL),   Q8VF61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000073172   ⟸   ENSMUST00000073468
RefSeq Acc Id: ENSMUSP00000149113   ⟸   ENSMUST00000216184
RefSeq Acc Id: ENSMUSP00000149523   ⟸   ENSMUST00000216367
RefSeq Acc Id: ENSMUSP00000149411   ⟸   ENSMUST00000214501
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000070459 Ensembl, UniProtKB/TrEMBL
  ENSMUSG00000116179 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000073468 ENTREZGENE
  ENSMUST00000073468.5 UniProtKB/TrEMBL
  ENSMUST00000214501.3 UniProtKB/TrEMBL
  ENSMUST00000216184.2 UniProtKB/TrEMBL
  ENSMUST00000216367.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258411 UniProtKB/TrEMBL
MGD MGI:3030124 ENTREZGENE
NCBI Gene 258411 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5ae1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TS13 ENTREZGENE, UniProtKB/TrEMBL
  Q8VF61 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5ae1  olfactory receptor family 5 subfamily AE member 1  Olfr290  olfactory receptor 290  Symbol and/or name change 5135510 APPROVED