Fhip2b (FHF complex subunit HOOK interacting protein 2B) - Rat Genome Database

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Gene: Fhip2b (FHF complex subunit HOOK interacting protein 2B) Mus musculus
Analyze
Symbol: Fhip2b
Name: FHF complex subunit HOOK interacting protein 2B
RGD ID: 1614142
MGI Page MGI
Description: Orthologous to human FHIP2B (FHF complex subunit HOOK interacting protein 2B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam160b2; family with sequence similarity 160, member B2; FHF complex subunit HOOK-interacting protein 2B; G430067P06Rik; Ra; Rai16; retinoic acid induced 16; retinoic acid-induced protein 16
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,820,733 - 70,837,309 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,820,736 - 70,837,275 (-)EnsemblGRCm39 Ensembl
GRCm381470,583,295 - 70,599,835 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,583,296 - 70,599,835 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,983,102 - 70,999,642 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,318,374 - 69,337,634 (-)NCBIMGSCv36mm8
Celera1468,124,822 - 68,141,336 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21267068   PMID:21677750   PMID:28378742   PMID:31862898   PMID:32212159   PMID:32289885   PMID:38355793  


Genomics

Comparative Map Data
Fhip2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,820,733 - 70,837,309 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,820,736 - 70,837,275 (-)EnsemblGRCm39 Ensembl
GRCm381470,583,295 - 70,599,835 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,583,296 - 70,599,835 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,983,102 - 70,999,642 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,318,374 - 69,337,634 (-)NCBIMGSCv36mm8
Celera1468,124,822 - 68,141,336 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
FHIP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,089,150 - 22,104,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,089,150 - 22,104,911 (+)EnsemblGRCh38hg38GRCh38
GRCh37821,946,661 - 21,962,422 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,002,660 - 22,017,836 (+)NCBINCBI36Build 36hg18NCBI36
Build 34822,002,659 - 22,017,835NCBI
Celera820,908,996 - 20,924,174 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,466,340 - 20,504,422 (+)NCBIHuRef
CHM1_1822,148,371 - 22,163,536 (+)NCBICHM1_1
T2T-CHM13v2.0822,363,108 - 22,378,867 (+)NCBIT2T-CHM13v2.0
Fhip2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81552,066,341 - 52,084,296 (-)NCBIGRCr8
mRatBN7.21545,656,641 - 45,674,603 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,656,647 - 45,674,105 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,774,496 - 49,791,959 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,886,003 - 50,903,468 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,745,315 - 47,762,779 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,271,495 - 52,288,938 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,271,496 - 52,288,893 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,995,012 - 56,012,410 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,983,167 - 51,000,626 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11551,001,939 - 51,018,655 (-)NCBI
Celera1545,334,681 - 45,352,170 (-)NCBICelera
Cytogenetic Map15p11NCBI
Fhip2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,587,970 - 45,597,700 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,587,970 - 45,597,700 (+)NCBIChiLan1.0ChiLan1.0
FHIP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,591,098 - 40,606,212 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,314,664 - 16,331,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,333,581 - 21,349,344 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,274,581 - 18,289,332 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,279,023 - 18,287,880 (+)Ensemblpanpan1.1panPan2
FHIP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,144,949 - 35,157,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,146,390 - 35,162,394 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,734,526 - 35,750,536 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,356,487 - 35,372,501 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,356,495 - 35,372,480 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,301,734 - 35,317,737 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,156,265 - 35,172,265 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,311,757 - 35,327,760 (-)NCBIUU_Cfam_GSD_1.0
Fhip2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,642,474 - 12,654,923 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,918,339 - 5,928,539 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,918,354 - 5,928,036 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FHIP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,360,412 - 6,376,922 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,360,333 - 6,376,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,795,952 - 6,812,571 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FHIP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,159,036 - 20,173,973 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,167,153 - 20,172,511 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605222,062,840 - 22,077,782 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fhip2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,677,843 - 17,689,446 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,677,862 - 17,690,799 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fhip2b
631 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:909
Count of miRNA genes:444
Interacting mature miRNAs:548
Transcripts:ENSMUST00000022690
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1470071977104071977Mouse

Markers in Region
RH129121  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381470,603,673 - 70,603,846UniSTSGRCm38
MGSCv371471,003,480 - 71,003,653UniSTSGRCm37
Celera1468,145,201 - 68,145,374UniSTS
Cytogenetic Map14D2UniSTS
cM Map1438.0UniSTS
AI325486  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381470,603,724 - 70,603,942UniSTSGRCm38
MGSCv371471,003,531 - 71,003,749UniSTSGRCm37
Celera1468,145,252 - 68,145,470UniSTS
Cytogenetic Map14D2UniSTS
cM Map1438.0UniSTS
Whitehead/MRC_RH14796.07UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022690   ⟹   ENSMUSP00000022690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1470,820,736 - 70,837,275 (-)Ensembl
GRCm38.p6 Ensembl1470,583,296 - 70,599,835 (-)Ensembl
RefSeq Acc Id: NM_194345   ⟹   NP_919326
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,820,735 - 70,837,275 (-)NCBI
GRCm381470,583,295 - 70,599,835 (-)NCBI
MGSCv371470,983,102 - 70,999,642 (-)RGD
Celera1468,124,822 - 68,141,336 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518998   ⟹   XP_006519061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,820,733 - 70,837,261 (-)NCBI
GRCm381470,583,295 - 70,599,823 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017316016   ⟹   XP_017171505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,820,733 - 70,827,884 (-)NCBI
GRCm381470,583,295 - 70,590,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036158590   ⟹   XP_036014483
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,820,733 - 70,837,309 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036158591   ⟹   XP_036014484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391470,820,733 - 70,827,880 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_919326   ⟸   NM_194345
- UniProtKB: Q6PED9 (UniProtKB/Swiss-Prot),   Q8C1Y2 (UniProtKB/Swiss-Prot),   Q80YR2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006519061   ⟸   XM_006518998
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017171505   ⟸   XM_017316016
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSMUSP00000022690   ⟸   ENSMUST00000022690
RefSeq Acc Id: XP_036014483   ⟸   XM_036158590
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036014484   ⟸   XM_036158591
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80YR2-F1-model_v2 AlphaFold Q80YR2 1-744 view protein structure

Promoters
RGD ID:8682932
Promoter ID:EPDNEW_M19497
Type:initiation region
Name:Fam160b2_1
Description:Mus musculus family with sequence similarity 160, member B2 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381470,599,845 - 70,599,905EPDNEW
RGD ID:6824933
Promoter ID:MM_KWN:17391
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   Brain,   Spleen
Transcripts:AK090035_FAM160B2,   UC007UOL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361470,988,441 - 70,989,612 (-)MPROMDB
RGD ID:6824915
Promoter ID:MM_KWN:17393
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6
Transcripts:ENSMUST00000022690,   ENSMUST00000116455
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361470,999,366 - 70,999,866 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3036290 AgrOrtholog
Ensembl Genes ENSMUSG00000022095 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022690 ENTREZGENE
  ENSMUST00000022690.10 UniProtKB/Swiss-Prot
InterPro FHIP_C UniProtKB/Swiss-Prot
  FHIP_KELAA_motif UniProtKB/Swiss-Prot
  RetinoicA-induced_16-like UniProtKB/Swiss-Prot
KEGG Report mmu:239170 UniProtKB/Swiss-Prot
MGD MGI:3036290 ENTREZGENE
NCBI Gene 239170 ENTREZGENE
PANTHER FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2B UniProtKB/Swiss-Prot
  PTHR21705 UniProtKB/Swiss-Prot
Pfam DUF5917 UniProtKB/Swiss-Prot
  KELAA UniProtKB/Swiss-Prot
  RAI16-like UniProtKB/Swiss-Prot
PhenoGen Fhip2b PhenoGen
UniProt F16B2_MOUSE UniProtKB/Swiss-Prot
  Q6PED9 ENTREZGENE
  Q80YR2 ENTREZGENE
  Q8C1Y2 ENTREZGENE
UniProt Secondary Q6PED9 UniProtKB/Swiss-Prot
  Q8C1Y2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-06-28 Fhip2b  FHF complex subunit HOOK interacting protein 2B  Fam160b2  family with sequence similarity 160, member B2  Symbol and/or name updated 27372883 PROVISIONAL