Mirlet7g (microRNA let7g) - Rat Genome Database

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Gene: Mirlet7g (microRNA let7g) Mus musculus
Analyze
Symbol: Mirlet7g
Name: microRNA let7g
RGD ID: 1607639
MGI Page MGI
Description: Enables mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Acts upstream of or within several processes, including cellular response to lipid; cellular senescence; and miRNA-mediated gene silencing by inhibition of translation. Part of RISC complex. Is expressed in cerebellum and telencephalon. Orthologous to human MIRLET7G (microRNA let-7g).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: let-7g; Mirnl; Mirnlet7g; mmu-let-7; mmu-let-7g
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,056,039 - 106,056,126 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,056,039 - 106,056,126 (+)EnsemblGRCm39 Ensembl
GRCm389106,178,840 - 106,178,927 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,178,840 - 106,178,927 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,081,171 - 106,081,258 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera9105,803,963 - 105,804,050 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12007417   PMID:15538371   PMID:16381832   PMID:16766679   PMID:16882971   PMID:17369397   PMID:17604727   PMID:18452032   PMID:18723672   PMID:18762567   PMID:19153603   PMID:19949436  
PMID:20215419   PMID:20413612   PMID:21037258   PMID:21267068   PMID:21718763   PMID:21993888   PMID:22013165   PMID:22078496   PMID:22910415   PMID:23185045   PMID:23200853   PMID:23630078  
PMID:23646144   PMID:24613920   PMID:25751060   PMID:26139524   PMID:27417237   PMID:28049690   PMID:28535009   PMID:28820723   PMID:30042178   PMID:30422318   PMID:30635573   PMID:31373834  
PMID:32109384   PMID:34289374   PMID:36121415   PMID:36136742   PMID:37868985  


Genomics

Comparative Map Data
Mirlet7g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,056,039 - 106,056,126 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,056,039 - 106,056,126 (+)EnsemblGRCm39 Ensembl
GRCm389106,178,840 - 106,178,927 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,178,840 - 106,178,927 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,081,171 - 106,081,258 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera9105,803,963 - 105,804,050 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.46NCBI
MIRLET7G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,268,278 - 52,268,361 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,268,278 - 52,268,361 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,302,294 - 52,302,377 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,277,333 - 52,277,416 (-)NCBINCBI36Build 36hg18NCBI36
Celera352,281,606 - 52,281,689 (-)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef352,364,465 - 52,364,548 (-)NCBIHuRef
CHM1_1352,254,824 - 52,254,907 (-)NCBICHM1_1
T2T-CHM13v2.0352,301,168 - 52,301,251 (-)NCBIT2T-CHM13v2.0
Mirlet7g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,701,020 - 115,701,107 (+)NCBIGRCr8
mRatBN7.28106,822,293 - 106,822,380 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,822,280 - 106,822,388 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,446,859 - 112,446,946 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,646,020 - 110,646,107 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,488,826 - 108,488,913 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08114,874,457 - 114,874,544 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8114,874,454 - 114,874,550 (+)EnsemblRnor6.0rn6Rnor6.0
Celera8106,144,521 - 106,144,608 (+)NCBICelera
Cytogenetic Map8q32NCBI
MIRLET7G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,501,074 - 37,501,152 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,501,054 - 37,501,160 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,482,632 - 37,482,710 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,851,450 - 37,851,528 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,851,430 - 37,851,536 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,215,139 - 37,215,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,623,891 - 37,623,969 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,908,500 - 37,908,578 (+)NCBIUU_Cfam_GSD_1.0
MIRLET7G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,406,130 - 34,406,225 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,406,140 - 34,406,219 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,599,004 - 37,599,083 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mirlet7g
2 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:26499
Count of gene targets:10147
Count of transcripts:17214
Interacting mature miRNAs:mmu-let-7g-3p, mmu-let-7g-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083506
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9106,056,039 - 106,056,126 (+)Ensembl
GRCm38.p6 Ensembl9106,178,840 - 106,178,927 (+)Ensembl
RefSeq Acc Id: NR_029526
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399106,056,039 - 106,056,126 (+)NCBI
GRCm389106,178,840 - 106,178,927 (+)ENTREZGENE
MGSCv379106,081,171 - 106,081,258 (+)RGD
Celera9105,803,963 - 105,804,050 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Promoters
RGD ID:8670706
Promoter ID:EPDNEW_M13383
Type:single initiation site
Name:Mirlet7g_1
Description:Mus musculus microRNA let7g , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389106,178,925 - 106,178,985EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676800 AgrOrtholog
Ensembl Genes ENSMUSG00000065440 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083506 ENTREZGENE
MGD MGI:2676800 ENTREZGENE
miRBase MI0000137 ENTREZGENE
NCBI Gene 387249 ENTREZGENE
PhenoGen Mirlet7g PhenoGen
RNAcentral URS00000B0351 RNACentral
  URS00004AFF8D RNACentral
  URS0000595A16 RNACentral