CCDC106 (coiled-coil domain containing 106) - Rat Genome Database

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Gene: CCDC106 (coiled-coil domain containing 106) Homo sapiens
Analyze
Symbol: CCDC106
Name: coiled-coil domain containing 106
RGD ID: 1607037
HGNC Page HGNC:30181
Description: Located in cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: coiled-coil domain-containing protein 106; HSU79303; protein predicted by clone 23882; ZNF581
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,647,400 - 55,653,161 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,641,062 - 55,653,161 (+)EnsemblGRCh38hg38GRCh38
GRCh371956,158,766 - 56,164,527 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,850,766 - 60,856,339 (+)NCBINCBI36Build 36hg18NCBI36
Celera1953,201,244 - 53,206,819 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,469,438 - 52,475,013 (+)NCBIHuRef
CHM1_11956,152,612 - 56,158,187 (+)NCBICHM1_1
T2T-CHM13v2.01958,743,329 - 58,749,089 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IDA)
nucleoplasm  (IBA,IDA)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8619474   PMID:9110174   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15790807   PMID:16169070   PMID:16344560   PMID:20159018   PMID:21832049   PMID:21873635   PMID:25416956  
PMID:26186194   PMID:27107014   PMID:28460455   PMID:28514442   PMID:29892012   PMID:30885251   PMID:31515488   PMID:32296183   PMID:32707033   PMID:33023834   PMID:33961781   PMID:34921745  
PMID:35484984   PMID:35854676   PMID:36244648   PMID:36736316  


Genomics

Comparative Map Data
CCDC106
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,647,400 - 55,653,161 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,641,062 - 55,653,161 (+)EnsemblGRCh38hg38GRCh38
GRCh371956,158,766 - 56,164,527 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,850,766 - 60,856,339 (+)NCBINCBI36Build 36hg18NCBI36
Celera1953,201,244 - 53,206,819 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,469,438 - 52,475,013 (+)NCBIHuRef
CHM1_11956,152,612 - 56,158,187 (+)NCBICHM1_1
T2T-CHM13v2.01958,743,329 - 58,749,089 (+)NCBIT2T-CHM13v2.0
Ccdc106
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3975,056,870 - 5,063,784 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl75,023,552 - 5,063,784 (+)EnsemblGRCm39 Ensembl
GRCm3875,053,842 - 5,060,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl75,020,553 - 5,060,785 (+)EnsemblGRCm38mm10GRCm38
MGSCv3775,008,328 - 5,012,387 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,660,284 - 4,663,872 (+)NCBIMGSCv36mm8
Celera74,798,816 - 4,802,876 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.92NCBI
Ccdc106
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8177,808,723 - 77,812,816 (-)NCBIGRCr8
mRatBN7.2168,779,882 - 68,783,975 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,779,882 - 68,786,846 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,124,963 - 74,129,056 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,689,268 - 82,693,361 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0175,837,942 - 75,842,035 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,331,232 - 72,338,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,331,491 - 72,335,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0176,197,686 - 76,204,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,518,530 - 67,521,713 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera168,332,195 - 68,340,446 (+)NCBICelera
Cytogenetic Map1q12NCBI
Ccdc106
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567699,742 - 703,745 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955567699,551 - 703,745 (-)NCBIChiLan1.0ChiLan1.0
CCDC106
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,789,139 - 61,794,912 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,518,980 - 63,524,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,694,599 - 52,700,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,380,616 - 61,385,175 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,379,490 - 61,385,169 (+)Ensemblpanpan1.1panPan2
CCDC106
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,092,927 - 102,097,644 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,091,834 - 102,095,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,150,013 - 102,154,194 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01102,746,424 - 102,750,605 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,745,318 - 102,749,837 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,383,989 - 102,388,170 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,095,840 - 102,100,021 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01102,858,944 - 102,863,125 (-)NCBIUU_Cfam_GSD_1.0
Ccdc106
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,722,572 - 1,726,583 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936981171,119 - 176,393 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936981171,054 - 175,120 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC106
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,767,390 - 59,772,588 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,767,390 - 59,772,594 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CCDC106
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1648,238,043 - 48,243,379 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl648,239,453 - 48,242,940 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045894,613 - 900,579 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc106
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,762,837 - 1,766,438 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,762,639 - 1,766,773 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCDC106
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52612432-58581203)x3 copy number gain See cases [RCV000134174] Chr19:52612432..58581203 [GRCh38]
Chr19:53115685..59092570 [GRCh37]
Chr19:57807497..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52955056-58581203)x3 copy number gain See cases [RCV000134139] Chr19:52955056..58581203 [GRCh38]
Chr19:53458309..59092570 [GRCh37]
Chr19:58150121..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.42-13.43(chr19:55550939-57031576)x1 copy number loss See cases [RCV000135287] Chr19:55550939..57031576 [GRCh38]
Chr19:56062305..57542944 [GRCh37]
Chr19:60754117..62234756 [NCBI36]
Chr19:19q13.42-13.43		 likely pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.42-13.43(chr19:55048514-56972458)x3 copy number gain See cases [RCV000138139] Chr19:55048514..56972458 [GRCh38]
Chr19:55595687..57483826 [GRCh37]
Chr19:60251694..62175638 [NCBI36]
Chr19:19q13.42-13.43		 likely pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3 copy number gain See cases [RCV000142008] Chr19:52143873..58445521 [GRCh38]
Chr19:52647126..58956888 [GRCh37]
Chr19:57338938..63648700 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.42-13.43(chr19:55037146-56982033)x3 copy number gain See cases [RCV000142245] Chr19:55037146..56982033 [GRCh38]
Chr19:55548514..57493401 [GRCh37]
Chr19:60240326..62185213 [NCBI36]
Chr19:19q13.42-13.43		 uncertain significance
GRCh38/hg38 19q13.42(chr19:55066790-55789870)x3 copy number gain See cases [RCV000142067] Chr19:55066790..55789870 [GRCh38]
Chr19:55578158..56301236 [GRCh37]
Chr19:60269970..60993048 [NCBI36]
Chr19:19q13.42		 uncertain significance
chr19:56133299..57648277 complex variant complex Breast ductal adenocarcinoma [RCV000207023] Chr19:56133299..57648277 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:54344821-58956888)x3 copy number gain See cases [RCV000448186] Chr19:54344821..58956888 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
NM_001370470.1(CCDC106):c.164T>C (p.Leu55Pro) single nucleotide variant not specified [RCV004286744] Chr19:55649435 [GRCh38]
Chr19:56160801 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:55549385-57489784)x3 copy number gain See cases [RCV000510290] Chr19:55549385..57489784 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:55844155-57408007)x3 copy number gain See cases [RCV000511123] Chr19:55844155..57408007 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
Single allele deletion not provided [RCV000678017] Chr19:55583239..55929986 [GRCh38]
Chr19:56094605..56441352 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:55779884-56896574)x1 copy number loss not provided [RCV000684089] Chr19:55779884..56896574 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:54196216-58759679)x3 copy number gain not provided [RCV000684095] Chr19:54196216..58759679 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:54334195-56434037)x3 copy number gain not provided [RCV001259948] Chr19:54334195..56434037 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:55247893-56503347)x1 copy number loss not provided [RCV001834407] Chr19:55247893..56503347 [GRCh37]
Chr19:19q13.42-13.43		 likely pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:55434660-56463734)x1 copy number loss not provided [RCV002279751] Chr19:55434660..56463734 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
NM_001370470.1(CCDC106):c.212G>A (p.Arg71Lys) single nucleotide variant not specified [RCV004102456] Chr19:55649483 [GRCh38]
Chr19:56160849 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.89A>C (p.Asp30Ala) single nucleotide variant not specified [RCV004098498] Chr19:55649262 [GRCh38]
Chr19:56160628 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.122G>A (p.Arg41Gln) single nucleotide variant not specified [RCV004222969] Chr19:55649295 [GRCh38]
Chr19:56160661 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.40G>A (p.Asp14Asn) single nucleotide variant not specified [RCV004234257] Chr19:55649213 [GRCh38]
Chr19:56160579 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.10C>T (p.Arg4Trp) single nucleotide variant not specified [RCV004201203] Chr19:55649056 [GRCh38]
Chr19:56160422 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.167C>T (p.Ala56Val) single nucleotide variant not specified [RCV004111443] Chr19:55649438 [GRCh38]
Chr19:56160804 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.665T>C (p.Leu222Pro) single nucleotide variant not specified [RCV004138582] Chr19:55652568 [GRCh38]
Chr19:56163934 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.116C>A (p.Pro39His) single nucleotide variant not specified [RCV004112281] Chr19:55649289 [GRCh38]
Chr19:56160655 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.365G>A (p.Arg122His) single nucleotide variant not specified [RCV004215104] Chr19:55651334 [GRCh38]
Chr19:56162700 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.126A>T (p.Arg42Ser) single nucleotide variant not specified [RCV004271248] Chr19:55649299 [GRCh38]
Chr19:56160665 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.571G>C (p.Gly191Arg) single nucleotide variant not specified [RCV004279954] Chr19:55652474 [GRCh38]
Chr19:56163840 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:56080158-57672397)x1 copy number loss not specified [RCV003986104] Chr19:56080158..57672397 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
NM_001370470.1(CCDC106):c.731T>G (p.Leu244Arg) single nucleotide variant not specified [RCV004432613] Chr19:55652634 [GRCh38]
Chr19:56164000 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.37G>A (p.Asp13Asn) single nucleotide variant not specified [RCV004432610] Chr19:55649210 [GRCh38]
Chr19:56160576 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.325C>T (p.Arg109Trp) single nucleotide variant not specified [RCV004432609] Chr19:55651294 [GRCh38]
Chr19:56162660 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.409T>G (p.Ser137Ala) single nucleotide variant not specified [RCV004432611] Chr19:55651378 [GRCh38]
Chr19:56162744 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.511C>T (p.Arg171Trp) single nucleotide variant not specified [RCV004432612] Chr19:55651480 [GRCh38]
Chr19:56162846 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001370470.1(CCDC106):c.787C>G (p.Gln263Glu) single nucleotide variant not specified [RCV004432614] Chr19:55652690 [GRCh38]
Chr19:56164056 [GRCh37]
Chr19:19q13.42		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3434
Count of miRNA genes:731
Interacting mature miRNAs:846
Transcripts:ENST00000308964, ENST00000586790, ENST00000586864, ENST00000587213, ENST00000588740, ENST00000591241, ENST00000591578, ENST00000592996, ENST00000593069
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1839 1301 1455 289 1045 204 2542 1328 3627 359 1317 1348 92 962 1447 1
Low 588 1653 271 335 861 261 1815 866 106 60 140 264 83 1 242 1341 4 2
Below cutoff 12 36 40 2 1 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001370467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC008735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF054984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY927563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY927628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI755544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI907663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR450308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA360854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU354321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU354322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU354323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U79303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000308964   ⟹   ENSP00000309681
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,035 - 55,653,161 (+)Ensembl
RefSeq Acc Id: ENST00000586790   ⟹   ENSP00000465757
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,212 - 55,653,161 (+)Ensembl
RefSeq Acc Id: ENST00000586864
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,905 - 55,649,655 (+)Ensembl
RefSeq Acc Id: ENST00000587213   ⟹   ENSP00000468077
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,058 - 55,649,290 (+)Ensembl
RefSeq Acc Id: ENST00000588740   ⟹   ENSP00000468539
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,233 - 55,653,161 (+)Ensembl
RefSeq Acc Id: ENST00000591241   ⟹   ENSP00000466521
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,919 - 55,653,033 (+)Ensembl
RefSeq Acc Id: ENST00000591578   ⟹   ENSP00000466870
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,233 - 55,653,161 (+)Ensembl
RefSeq Acc Id: ENST00000592996   ⟹   ENSP00000466597
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,641,062 - 55,651,487 (+)Ensembl
RefSeq Acc Id: ENST00000593069   ⟹   ENSP00000468521
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,648,014 - 55,649,309 (+)Ensembl
RefSeq Acc Id: NM_001370467   ⟹   NP_001357396
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,647,400 - 55,653,161 (+)NCBI
T2T-CHM13v2.01958,743,329 - 58,749,089 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001370468   ⟹   NP_001357397
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,648,019 - 55,653,161 (+)NCBI
T2T-CHM13v2.01958,743,948 - 58,749,089 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001370469   ⟹   NP_001357398
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,648,019 - 55,653,161 (+)NCBI
T2T-CHM13v2.01958,743,948 - 58,749,089 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001370470   ⟹   NP_001357399
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,648,212 - 55,653,161 (+)NCBI
T2T-CHM13v2.01958,744,141 - 58,749,089 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001370471   ⟹   NP_001357400
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,648,212 - 55,653,161 (+)NCBI
T2T-CHM13v2.01958,744,141 - 58,749,089 (+)NCBI
Sequence:
RefSeq Acc Id: NM_013301   ⟹   NP_037433
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,647,588 - 55,653,161 (+)NCBI
GRCh371956,158,934 - 56,164,527 (+)NCBI
Build 361960,850,766 - 60,856,339 (+)NCBI Archive
Celera1953,201,244 - 53,206,819 (+)RGD
HuRef1952,469,438 - 52,475,013 (+)ENTREZGENE
CHM1_11956,152,612 - 56,158,187 (+)NCBI
T2T-CHM13v2.01958,743,517 - 58,749,089 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_037433   ⟸   NM_013301
- Peptide Label: isoform 1
- UniProtKB: D3K183 (UniProtKB/Swiss-Prot),   B3KUF9 (UniProtKB/Swiss-Prot),   Q99786 (UniProtKB/Swiss-Prot),   Q9BWC9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001357396   ⟸   NM_001370467
- Peptide Label: isoform 1
- UniProtKB: Q9BWC9 (UniProtKB/Swiss-Prot),   D3K183 (UniProtKB/Swiss-Prot),   B3KUF9 (UniProtKB/Swiss-Prot),   Q99786 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001357398   ⟸   NM_001370469
- Peptide Label: isoform 1
- UniProtKB: Q9BWC9 (UniProtKB/Swiss-Prot),   D3K183 (UniProtKB/Swiss-Prot),   B3KUF9 (UniProtKB/Swiss-Prot),   Q99786 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001357397   ⟸   NM_001370468
- Peptide Label: isoform 1
- UniProtKB: Q9BWC9 (UniProtKB/Swiss-Prot),   D3K183 (UniProtKB/Swiss-Prot),   B3KUF9 (UniProtKB/Swiss-Prot),   Q99786 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001357399   ⟸   NM_001370470
- Peptide Label: isoform 1
- UniProtKB: Q9BWC9 (UniProtKB/Swiss-Prot),   D3K183 (UniProtKB/Swiss-Prot),   B3KUF9 (UniProtKB/Swiss-Prot),   Q99786 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001357400   ⟸   NM_001370471
- Peptide Label: isoform 2
- UniProtKB: K7EMI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSP00000309681   ⟸   ENST00000308964
RefSeq Acc Id: ENSP00000465757   ⟸   ENST00000586790
RefSeq Acc Id: ENSP00000468077   ⟸   ENST00000587213
RefSeq Acc Id: ENSP00000468539   ⟸   ENST00000588740
RefSeq Acc Id: ENSP00000466870   ⟸   ENST00000591578
RefSeq Acc Id: ENSP00000466521   ⟸   ENST00000591241
RefSeq Acc Id: ENSP00000466597   ⟸   ENST00000592996
RefSeq Acc Id: ENSP00000468521   ⟸   ENST00000593069

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BWC9-F1-model_v2 AlphaFold Q9BWC9 1-280 view protein structure

Promoters
RGD ID:13205789
Promoter ID:EPDNEW_H26475
Type:initiation region
Name:CCDC106_2
Description:coiled-coil domain containing 106
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26467  EPDNEW_H26476  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,648,019 - 55,648,079EPDNEW
RGD ID:13205791
Promoter ID:EPDNEW_H26476
Type:initiation region
Name:CCDC106_1
Description:coiled-coil domain containing 106
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26467  EPDNEW_H26475  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,648,233 - 55,648,293EPDNEW
RGD ID:6795247
Promoter ID:HG_KWN:31080
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000308964,   UC002QLS.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361960,850,711 - 60,851,757 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30181 AgrOrtholog
COSMIC CCDC106 COSMIC
Ensembl Genes ENSG00000173581 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000308964 ENTREZGENE
  ENST00000308964.7 UniProtKB/Swiss-Prot
  ENST00000586790 ENTREZGENE
  ENST00000586790.6 UniProtKB/Swiss-Prot
  ENST00000587213.5 UniProtKB/TrEMBL
  ENST00000588740 ENTREZGENE
  ENST00000588740.5 UniProtKB/Swiss-Prot
  ENST00000591241 ENTREZGENE
  ENST00000591241.1 UniProtKB/TrEMBL
  ENST00000591578 ENTREZGENE
  ENST00000591578.5 UniProtKB/Swiss-Prot
  ENST00000592996.5 UniProtKB/TrEMBL
  ENST00000593069.1 UniProtKB/TrEMBL
GTEx ENSG00000173581 GTEx
HGNC ID HGNC:30181 ENTREZGENE
Human Proteome Map CCDC106 Human Proteome Map
InterPro CCDC106 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:29903 UniProtKB/Swiss-Prot
NCBI Gene 29903 ENTREZGENE
OMIM 613478 OMIM
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 106 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16477 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CCDC106 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA145008652 PharmGKB
UniProt B3KUF9 ENTREZGENE
  CC106_HUMAN UniProtKB/Swiss-Prot
  D3K183 ENTREZGENE
  K7EMI9 ENTREZGENE, UniProtKB/TrEMBL
  K7EMP7_HUMAN UniProtKB/TrEMBL
  K7ER22_HUMAN UniProtKB/TrEMBL
  K7ES29_HUMAN UniProtKB/TrEMBL
  Q99786 ENTREZGENE
  Q9BWC9 ENTREZGENE
UniProt Secondary B3KUF9 UniProtKB/Swiss-Prot
  D3K183 UniProtKB/Swiss-Prot
  Q99786 UniProtKB/Swiss-Prot