ECRG4 (ECRG4 augurin precursor) - Rat Genome Database

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Gene: ECRG4 (ECRG4 augurin precursor) Homo sapiens
Analyze
Symbol: ECRG4
Name: ECRG4 augurin precursor
RGD ID: 1603606
HGNC Page HGNC:24642
Description: Enables neuropeptide hormone activity. Involved in neuropeptide signaling pathway; positive regulation of hormone secretion; and vasopressin secretion. Located in apical plasma membrane; dense core granule; and extracellular space.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: augurin; C2orf40; chromosome 2 open reading frame 40; esophageal cancer related gene 4 protein; esophageal cancer-related gene 4 protein
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382106,063,241 - 106,078,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2106,063,246 - 106,078,155 (+)EnsemblGRCh38hg38GRCh38
GRCh372106,682,144 - 106,694,611 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362106,048,545 - 106,061,040 (+)NCBINCBI36Build 36hg18NCBI36
Celera2100,882,549 - 100,895,038 (+)NCBICelera
Cytogenetic Map2q12.2NCBI
HuRef2100,451,504 - 100,464,588 (+)NCBIHuRef
CHM1_12106,687,184 - 106,699,693 (+)NCBICHM1_1
T2T-CHM13v2.02106,524,934 - 106,539,858 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12800218   PMID:12975309   PMID:15489334   PMID:15815621   PMID:17284679   PMID:17786363   PMID:18029348   PMID:19521989   PMID:20017917   PMID:20598162   PMID:21288367  
PMID:21436262   PMID:21873635   PMID:21935431   PMID:22110708   PMID:22325214   PMID:22411956   PMID:22526622   PMID:22626786   PMID:22901147   PMID:23553029   PMID:23770814   PMID:23957914  
PMID:24058526   PMID:25326809   PMID:25378632   PMID:25511108   PMID:25707757   PMID:26165988   PMID:26276361   PMID:26631111   PMID:26762416   PMID:26823803   PMID:27119734   PMID:27175789  
PMID:28578429   PMID:28856538   PMID:28870864   PMID:29126922   PMID:29268240   PMID:29511297   PMID:29886034   PMID:30003403   PMID:30918105   PMID:31152845   PMID:31190084   PMID:31468282  
PMID:32195341   PMID:32296183   PMID:32513696   PMID:32814053   PMID:33417325   PMID:34551201   PMID:35676661  


Genomics

Comparative Map Data
ECRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382106,063,241 - 106,078,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2106,063,246 - 106,078,155 (+)EnsemblGRCh38hg38GRCh38
GRCh372106,682,144 - 106,694,611 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362106,048,545 - 106,061,040 (+)NCBINCBI36Build 36hg18NCBI36
Celera2100,882,549 - 100,895,038 (+)NCBICelera
Cytogenetic Map2q12.2NCBI
HuRef2100,451,504 - 100,464,588 (+)NCBIHuRef
CHM1_12106,687,184 - 106,699,693 (+)NCBICHM1_1
T2T-CHM13v2.02106,524,934 - 106,539,858 (+)NCBIT2T-CHM13v2.0
Ecrg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,769,762 - 43,781,724 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,769,762 - 43,781,738 (+)EnsemblGRCm39 Ensembl
GRCm38143,730,602 - 43,742,564 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl143,730,602 - 43,742,578 (+)EnsemblGRCm38mm10GRCm38
MGSCv37143,787,447 - 43,799,409 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36143,675,217 - 43,687,093 (+)NCBIMGSCv36mm8
Celera144,080,967 - 44,092,916 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map123.44NCBI
Ecrg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8953,485,040 - 53,504,691 (+)NCBIGRCr8
mRatBN7.2945,992,954 - 46,012,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl945,992,954 - 46,012,595 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx954,505,053 - 54,524,710 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0959,627,854 - 59,647,511 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0957,908,081 - 57,927,739 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0950,526,811 - 50,548,056 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl950,526,811 - 50,548,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0950,191,450 - 50,212,695 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4942,931,051 - 42,950,605 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1942,932,613 - 42,952,019 (+)NCBI
Celera943,707,081 - 43,725,077 (+)NCBICelera
Cytogenetic Map9q22NCBI
Ecrg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547010,645,750 - 10,659,388 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547010,646,585 - 10,655,311 (+)NCBIChiLan1.0ChiLan1.0
ECRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,649,852 - 21,664,951 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A21,652,519 - 21,667,716 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A95,762,149 - 95,774,834 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A107,141,822 - 107,152,977 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A107,140,895 - 107,152,967 (+)Ensemblpanpan1.1panPan2
ECRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11037,423,183 - 37,432,961 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1037,423,183 - 37,433,322 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1037,347,657 - 37,357,428 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01038,272,970 - 38,282,714 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1038,272,977 - 38,282,878 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11038,005,101 - 38,014,873 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01038,281,847 - 38,291,645 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01038,476,371 - 38,486,148 (-)NCBIUU_Cfam_GSD_1.0
ECRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl348,960,429 - 48,971,511 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1348,960,413 - 48,971,878 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2351,051,816 - 51,062,808 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ECRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1149,686,930 - 9,698,708 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl149,687,043 - 9,699,049 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041177,409,300 - 177,421,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ecrg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247499,947,188 - 9,956,983 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247499,947,366 - 9,956,876 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ECRG4
5 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q11.2-12.3(chr2:100378510-108472871)x3 copy number gain See cases [RCV000050836] Chr2:100378510..108472871 [GRCh38]
Chr2:100994972..109089327 [GRCh37]
Chr2:100361404..108455759 [NCBI36]
Chr2:2q11.2-12.3		 pathogenic
GRCh38/hg38 2q12.2-12.3(chr2:105828398-108080417)x3 copy number gain See cases [RCV000052691] Chr2:105828398..108080417 [GRCh38]
Chr2:106444854..108696873 [GRCh37]
Chr2:105811286..108063305 [NCBI36]
Chr2:2q12.2-12.3		 uncertain significance
GRCh38/hg38 2q11.2-13(chr2:97672522-110211318)x3 copy number gain See cases [RCV000052947] Chr2:97672522..110211318 [GRCh38]
Chr2:98288985..110968895 [GRCh37]
Chr2:97655417..110326184 [NCBI36]
Chr2:2q11.2-13		 pathogenic
GRCh38/hg38 2q11.2-12.2(chr2:102084275-106085903)x1 copy number loss See cases [RCV000134974] Chr2:102084275..106085903 [GRCh38]
Chr2:102700735..106702359 [GRCh37]
Chr2:102067167..106068791 [NCBI36]
Chr2:2q11.2-12.2		 likely pathogenic
GRCh38/hg38 2q12.1-12.3(chr2:104381722-107312459)x1 copy number loss See cases [RCV000135282] Chr2:104381722..107312459 [GRCh38]
Chr2:104998180..107928915 [GRCh37]
Chr2:104364612..107295347 [NCBI36]
Chr2:2q12.1-12.3		 likely pathogenic
GRCh38/hg38 2q12.1-12.2(chr2:105239034-106152100)x3 copy number gain See cases [RCV000135475] Chr2:105239034..106152100 [GRCh38]
Chr2:105855491..106768556 [GRCh37]
Chr2:105221923..106134988 [NCBI36]
Chr2:2q12.1-12.2		 benign
GRCh38/hg38 2q11.2-13(chr2:101710825-110791418)x3 copy number gain See cases [RCV000138645] Chr2:101710825..110791418 [GRCh38]
Chr2:102327287..111548995 [GRCh37]
Chr2:101693719..111265466 [NCBI36]
Chr2:2q11.2-13		 pathogenic
GRCh38/hg38 2q11.1-13(chr2:94678532-110602409)x3 copy number gain See cases [RCV000141075] Chr2:94678532..110602409 [GRCh38]
Chr2:95344257..111359986 [GRCh37]
Chr2:94707984..111076455 [NCBI36]
Chr2:2q11.1-13		 pathogenic
GRCh38/hg38 2q11.2-12.2(chr2:100478285-106498909)x3 copy number gain See cases [RCV000141445] Chr2:100478285..106498909 [GRCh38]
Chr2:101094747..107115365 [GRCh37]
Chr2:100461179..106481797 [NCBI36]
Chr2:2q11.2-12.2		 uncertain significance
GRCh37/hg19 2q12.2-14.1(chr2:106423310-115054828)x1 copy number loss See cases [RCV000240053] Chr2:106423310..115054828 [GRCh37]
Chr2:2q12.2-14.1		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q11.1-12.3(chr2:95529039-108518266) copy number gain See cases [RCV000449270] Chr2:95529039..108518266 [GRCh37]
Chr2:2q11.1-12.3		 pathogenic
GRCh37/hg19 2q11.1-13(chr2:95327499-111370025)x4 copy number gain See cases [RCV000446842] Chr2:95327499..111370025 [GRCh37]
Chr2:2q11.1-13		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q11.1-12.2(chr2:95518497-107186127) copy number gain See cases [RCV000511158] Chr2:95518497..107186127 [GRCh37]
Chr2:2q11.1-12.2		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q12.1-24.3(chr2:104172062-168223828)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626436] Chr2:104172062..168223828 [GRCh37]
Chr2:2q12.1-24.3		 drug response
GRCh37/hg19 2q11.1-13(chr2:96353030-114045463)x3 copy number gain not provided [RCV000682168] Chr2:96353030..114045463 [GRCh37]
Chr2:2q11.1-13		 pathogenic
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
GRCh37/hg19 2q12.2(chr2:106690493-106700313)x3 copy number gain not provided [RCV000753075] Chr2:106690493..106700313 [GRCh37]
Chr2:2q12.2		 benign
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q12.2(chr2:106691039-106705747)x3 copy number gain not provided [RCV000740544] Chr2:106691039..106705747 [GRCh37]
Chr2:2q12.2		 benign
GRCh37/hg19 2q12.2(chr2:106692818-106700313)x3 copy number gain not provided [RCV000740545] Chr2:106692818..106700313 [GRCh37]
Chr2:2q12.2		 benign
GRCh37/hg19 2q12.2(chr2:106547252-106992981)x3 copy number gain not provided [RCV001005301] Chr2:106547252..106992981 [GRCh37]
Chr2:2q12.2		 uncertain significance
GRCh37/hg19 2q12.2-12.3(chr2:106596090-107516533)x3 copy number gain not provided [RCV000848935] Chr2:106596090..107516533 [GRCh37]
Chr2:2q12.2-12.3		 uncertain significance
GRCh37/hg19 2q12.1-12.2(chr2:102917327-106755564)x1 copy number loss not provided [RCV000848959] Chr2:102917327..106755564 [GRCh37]
Chr2:2q12.1-12.2		 uncertain significance
NM_032411.3(ECRG4):c.154G>A (p.Ala52Thr) single nucleotide variant not provided [RCV000946626] Chr2:106073912 [GRCh38]
Chr2:106690368 [GRCh37]
Chr2:2q12.2		 benign
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13		 pathogenic
GRCh37/hg19 2q12.1-12.2(chr2:105674582-106762678)x1 copy number loss not specified [RCV003986360] Chr2:105674582..106762678 [GRCh37]
Chr2:2q12.1-12.2		 uncertain significance
NM_032411.3(ECRG4):c.140C>G (p.Thr47Ser) single nucleotide variant not specified [RCV004384447] Chr2:106073898 [GRCh38]
Chr2:106690354 [GRCh37]
Chr2:2q12.2		 uncertain significance
NM_032411.3(ECRG4):c.371A>T (p.Asp124Val) single nucleotide variant not specified [RCV004384448] Chr2:106077850 [GRCh38]
Chr2:106694306 [GRCh37]
Chr2:2q12.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:694
Count of miRNA genes:451
Interacting mature miRNAs:487
Transcripts:ENST00000238044, ENST00000409944, ENST00000437659, ENST00000479337, ENST00000489174, ENST00000493478
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH69278  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372106,694,370 - 106,694,578UniSTSGRCh37
Build 362106,060,802 - 106,061,010RGDNCBI36
Celera2100,894,797 - 100,895,005RGD
Cytogenetic Map2q12.2UniSTS
HuRef2100,464,347 - 100,464,555UniSTS
GeneMap99-GB4 RH Map2366.65UniSTS
NCBI RH Map2785.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1 1
Medium 1772 1463 1010 84 204 1 2222 907 1219 133 974 1097 83 1047 1517
Low 497 830 463 306 420 227 1999 1170 2420 188 355 272 82 1 157 1247 4 2
Below cutoff 57 648 207 196 809 195 65 74 42 47 43 73 3 24

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_032411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006712799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011511993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017005106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047446022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047446023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC018878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF325503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS072958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB740500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF584267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000238044   ⟹   ENSP00000238044
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2106,065,688 - 106,078,155 (+)Ensembl
RefSeq Acc Id: ENST00000409944   ⟹   ENSP00000386421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2106,063,294 - 106,078,155 (+)Ensembl
RefSeq Acc Id: ENST00000437659   ⟹   ENSP00000388664
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2106,065,800 - 106,077,900 (+)Ensembl
RefSeq Acc Id: ENST00000479337
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2106,073,818 - 106,078,155 (+)Ensembl
RefSeq Acc Id: ENST00000489174
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2106,063,257 - 106,074,239 (+)Ensembl
RefSeq Acc Id: ENST00000493478
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2106,063,246 - 106,072,401 (+)Ensembl
RefSeq Acc Id: NM_032411   ⟹   NP_115787
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,065,688 - 106,078,155 (+)NCBI
GRCh372106,682,113 - 106,694,611 (+)ENTREZGENE
Build 362106,048,545 - 106,061,040 (+)NCBI Archive
HuRef2100,451,504 - 100,464,588 (+)ENTREZGENE
CHM1_12106,687,184 - 106,699,693 (+)NCBI
T2T-CHM13v2.02106,527,368 - 106,539,858 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006712799   ⟹   XP_006712862
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,063,241 - 106,078,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011511993   ⟹   XP_011510295
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,063,241 - 106,078,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047446022   ⟹   XP_047301978
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,063,241 - 106,078,155 (+)NCBI
RefSeq Acc Id: XM_047446023   ⟹   XP_047301979
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,063,241 - 106,078,155 (+)NCBI
RefSeq Acc Id: XM_054344197   ⟹   XP_054200172
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02106,524,934 - 106,539,858 (+)NCBI
RefSeq Acc Id: XM_054344198   ⟹   XP_054200173
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02106,524,970 - 106,539,858 (+)NCBI
RefSeq Acc Id: XM_054344199   ⟹   XP_054200174
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02106,524,970 - 106,539,858 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_115787   ⟸   NM_032411
- Peptide Label: precursor
- UniProtKB: D3DVK2 (UniProtKB/Swiss-Prot),   Q9H1Z8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006712862   ⟸   XM_006712799
- Peptide Label: isoform X2
- UniProtKB: B8ZZE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011510295   ⟸   XM_011511993
- Peptide Label: isoform X2
- UniProtKB: B8ZZE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000388664   ⟸   ENST00000437659
RefSeq Acc Id: ENSP00000386421   ⟸   ENST00000409944
RefSeq Acc Id: ENSP00000238044   ⟸   ENST00000238044
RefSeq Acc Id: XP_047301978   ⟸   XM_047446022
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047301979   ⟸   XM_047446023
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054200172   ⟸   XM_054344197
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054200173   ⟸   XM_054344198
- Peptide Label: isoform X2
- UniProtKB: B8ZZE5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054200174   ⟸   XM_054344199
- Peptide Label: isoform X2
- UniProtKB: B8ZZE5 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9H1Z8-F1-model_v2 AlphaFold Q9H1Z8 1-148 view protein structure

Promoters
RGD ID:6861248
Promoter ID:EPDNEW_H3789
Type:multiple initiation site
Name:C2orf40_2
Description:chromosome 2 open reading frame 40
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3790  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,063,241 - 106,063,301EPDNEW
RGD ID:6861250
Promoter ID:EPDNEW_H3790
Type:initiation region
Name:C2orf40_1
Description:chromosome 2 open reading frame 40
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3789  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382106,065,688 - 106,065,748EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:24642 AgrOrtholog
COSMIC ECRG4 COSMIC
Ensembl Genes ENSG00000119147 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000238044 ENTREZGENE
  ENST00000238044.8 UniProtKB/Swiss-Prot
  ENST00000409944 ENTREZGENE
  ENST00000409944.5 UniProtKB/TrEMBL
  ENST00000437659 ENTREZGENE
  ENST00000437659.1 UniProtKB/TrEMBL
GTEx ENSG00000119147 GTEx
HGNC ID HGNC:24642 ENTREZGENE
Human Proteome Map ECRG4 Human Proteome Map
InterPro Augurin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:84417 UniProtKB/Swiss-Prot
NCBI Gene 84417 ENTREZGENE
OMIM 611752 OMIM
PANTHER AUGURIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR31613 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Augurin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA147358728 PharmGKB
UniProt AUGN_HUMAN UniProtKB/Swiss-Prot
  B8ZZE5 ENTREZGENE, UniProtKB/TrEMBL
  C9JRR0_HUMAN UniProtKB/TrEMBL
  D3DVK2 ENTREZGENE
  Q9H1Z8 ENTREZGENE
UniProt Secondary D3DVK2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-23 ECRG4  ECRG4 augurin precursor  C2orf40  chromosome 2 open reading frame 40  Symbol and/or name change 5135510 APPROVED