CTU1 (cytosolic thiouridylase subunit 1) - Rat Genome Database

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Gene: CTU1 (cytosolic thiouridylase subunit 1) Homo sapiens
Analyze
Symbol: CTU1
Name: cytosolic thiouridylase subunit 1
RGD ID: 1602450
HGNC Page HGNC:29590
Description: Predicted to enable tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Predicted to be part of cytosolic tRNA wobble base thiouridylase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP binding domain 3; ATP-binding domain-containing protein 3; ATPBD3; cancer-associated gene protein; cancer-associated protein; cytoplasmic tRNA 2-thiolation protein 1; cytoplasmic tRNA adenylyltransferase 1; cytosolic thiouridylase subunit 1 homolog; MGC17332; NCS6
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC339352  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,097,606 - 51,108,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,097,606 - 51,108,409 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,600,863 - 51,611,666 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,293,587 - 56,299,659 (-)NCBINCBI36Build 36hg18NCBI36
Celera1948,652,948 - 48,663,731 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1947,934,059 - 47,944,843 (-)NCBIHuRef
CHM1_11951,602,851 - 51,613,631 (-)NCBICHM1_1
T2T-CHM13v2.01954,186,212 - 54,197,016 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:16964243   PMID:19017811   PMID:20877624   PMID:21209336   PMID:21873635   PMID:22678362   PMID:23891004   PMID:26186194   PMID:28514442   PMID:28561026  
PMID:31091453   PMID:33961781   PMID:34373451   PMID:35256949   PMID:35563538   PMID:37689310  


Genomics

Comparative Map Data
CTU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,097,606 - 51,108,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,097,606 - 51,108,409 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,600,863 - 51,611,666 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,293,587 - 56,299,659 (-)NCBINCBI36Build 36hg18NCBI36
Celera1948,652,948 - 48,663,731 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1947,934,059 - 47,944,843 (-)NCBIHuRef
CHM1_11951,602,851 - 51,613,631 (-)NCBICHM1_1
T2T-CHM13v2.01954,186,212 - 54,197,016 (-)NCBIT2T-CHM13v2.0
Ctu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,321,400 - 43,327,724 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,321,440 - 43,327,722 (+)EnsemblGRCm39 Ensembl
GRCm38743,671,971 - 43,678,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,672,016 - 43,678,298 (+)EnsemblGRCm38mm10GRCm38
MGSCv37750,927,401 - 50,933,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,540,073 - 43,546,340 (+)NCBIMGSCv36mm8
Celera739,136,142 - 39,142,406 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.26NCBI
Ctu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81103,251,983 - 103,257,778 (+)NCBIGRCr8
mRatBN7.2194,115,431 - 94,121,224 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl194,115,420 - 94,121,221 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,500,862 - 99,506,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01107,973,522 - 107,979,314 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01101,256,902 - 101,262,693 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,599,608 - 99,605,412 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,599,620 - 99,605,412 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01100,668,356 - 100,674,148 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,083,641 - 94,089,433 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1194,163,849 - 94,166,542 (+)NCBI
Celera188,384,549 - 88,390,341 (+)NCBICelera
Cytogenetic Map1q22NCBI
Ctu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955558959,819 - 960,369 (-)NCBIChiLan1.0ChiLan1.0
CTU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,167,965 - 57,177,933 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,089,406 - 59,099,402 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,065,741 - 48,075,758 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,953,113 - 56,963,262 (-)NCBIpanpan1.1PanPan1.1panPan2
CTU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,795,273 - 105,800,722 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,367,922 - 105,373,684 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,304,349 - 106,310,133 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,304,316 - 106,310,133 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,976,104 - 105,981,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,617,196 - 105,623,369 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,412,402 - 106,418,193 (+)NCBIUU_Cfam_GSD_1.0
Ctu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,852,966 - 22,859,793 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936889728,362 - 733,141 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936889728,956 - 735,692 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100516084
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1658,388,646 - 58,396,509 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,793,971 - 51,799,336 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CTU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1644,117,233 - 44,132,657 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl644,117,331 - 44,124,145 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607324,163,516 - 24,174,918 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248323,433,809 - 3,438,847 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CTU1
18 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_145232.4(CTU1):c.845C>G (p.Pro282Arg) single nucleotide variant not specified [RCV004316868] Chr19:51098803 [GRCh38]
Chr19:51602060 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_145232.4(CTU1):c.907G>T (p.Ala303Ser) single nucleotide variant not specified [RCV004319240] Chr19:51098741 [GRCh38]
Chr19:51601998 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.41(chr19:50469730-51916485)x3 copy number gain not provided [RCV001007055] Chr19:50469730..51916485 [GRCh37]
Chr19:19q13.33-13.41		 uncertain significance
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42		 not provided
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438) copy number gain not specified [RCV002052689] Chr19:49911081..53127438 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
NM_145232.4(CTU1):c.208G>A (p.Val70Met) single nucleotide variant not specified [RCV004217800] Chr19:51104362 [GRCh38]
Chr19:51607619 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.461C>G (p.Ala154Gly) single nucleotide variant not specified [RCV004202010] Chr19:51104109 [GRCh38]
Chr19:51607366 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.56C>T (p.Pro19Leu) single nucleotide variant not specified [RCV004095249] Chr19:51104514 [GRCh38]
Chr19:51607771 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.964C>G (p.Arg322Gly) single nucleotide variant not specified [RCV004182124] Chr19:51098684 [GRCh38]
Chr19:51601941 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.887G>A (p.Arg296His) single nucleotide variant not specified [RCV004076018] Chr19:51098761 [GRCh38]
Chr19:51602018 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.836C>A (p.Ala279Glu) single nucleotide variant not specified [RCV004239997] Chr19:51098812 [GRCh38]
Chr19:51602069 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.460G>C (p.Ala154Pro) single nucleotide variant not specified [RCV004165037] Chr19:51104110 [GRCh38]
Chr19:51607367 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.146C>T (p.Pro49Leu) single nucleotide variant not specified [RCV004264203] Chr19:51104424 [GRCh38]
Chr19:51607681 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.604G>A (p.Gly202Ser) single nucleotide variant not specified [RCV004331693] Chr19:51099044 [GRCh38]
Chr19:51602301 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.718G>A (p.Ala240Thr) single nucleotide variant not specified [RCV004273810] Chr19:51098930 [GRCh38]
Chr19:51602187 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.1015C>T (p.Pro339Ser) single nucleotide variant not specified [RCV004290659] Chr19:51098633 [GRCh38]
Chr19:51601890 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.886C>A (p.Arg296Ser) single nucleotide variant not specified [RCV004302060] Chr19:51098762 [GRCh38]
Chr19:51602019 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.941G>A (p.Arg314His) single nucleotide variant not specified [RCV004365894] Chr19:51098707 [GRCh38]
Chr19:51601964 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
NM_145232.4(CTU1):c.51C>A (p.Arg17=) single nucleotide variant not provided [RCV003415395] Chr19:51104519 [GRCh38]
Chr19:51607776 [GRCh37]
Chr19:19q13.41		 likely benign
GRCh37/hg19 19q13.33-13.41(chr19:48905537-51614930)x3 copy number gain not specified [RCV003986127] Chr19:48905537..51614930 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
NM_145232.4(CTU1):c.1036C>T (p.Pro346Ser) single nucleotide variant not specified [RCV004375155] Chr19:51098612 [GRCh38]
Chr19:51601869 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.392C>T (p.Ala131Val) single nucleotide variant not specified [RCV004375157] Chr19:51104178 [GRCh38]
Chr19:51607435 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.509G>A (p.Gly170Asp) single nucleotide variant not specified [RCV004375158] Chr19:51099139 [GRCh38]
Chr19:51602396 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.556C>T (p.Arg186Trp) single nucleotide variant not specified [RCV004375159] Chr19:51099092 [GRCh38]
Chr19:51602349 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.590G>A (p.Gly197Asp) single nucleotide variant not specified [RCV004375160] Chr19:51099058 [GRCh38]
Chr19:51602315 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.610G>T (p.Gly204Trp) single nucleotide variant not specified [RCV004375162] Chr19:51099038 [GRCh38]
Chr19:51602295 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.907G>A (p.Ala303Thr) single nucleotide variant not specified [RCV004375168] Chr19:51098741 [GRCh38]
Chr19:51601998 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.848G>C (p.Arg283Pro) single nucleotide variant not specified [RCV004375166] Chr19:51098800 [GRCh38]
Chr19:51602057 [GRCh37]
Chr19:19q13.41		 likely benign
NM_145232.4(CTU1):c.172G>A (p.Ala58Thr) single nucleotide variant not specified [RCV004375156] Chr19:51104398 [GRCh38]
Chr19:51607655 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.832G>A (p.Ala278Thr) single nucleotide variant not specified [RCV004375165] Chr19:51098816 [GRCh38]
Chr19:51602073 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.614G>A (p.Gly205Asp) single nucleotide variant not specified [RCV004375163] Chr19:51099034 [GRCh38]
Chr19:51602291 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_145232.4(CTU1):c.631C>G (p.Arg211Gly) single nucleotide variant not specified [RCV004375164] Chr19:51099017 [GRCh38]
Chr19:51602274 [GRCh37]
Chr19:19q13.41		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:505
Count of miRNA genes:379
Interacting mature miRNAs:412
Transcripts:ENST00000421832
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 194 40 174 22 300 25 178 81 199 39 435 303 9 28 57 1
Low 2245 2917 1552 602 1617 440 4153 2076 3524 380 1025 1310 166 1 1176 2705 5 2
Below cutoff 34 26 26 38 11 26

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000421832   ⟹   ENSP00000390011
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1951,097,606 - 51,108,409 (-)Ensembl
RefSeq Acc Id: NM_145232   ⟹   NP_660275
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381951,097,606 - 51,108,409 (-)NCBI
GRCh371951,600,863 - 51,611,647 (-)RGD
Build 361956,293,587 - 56,299,659 (-)NCBI Archive
Celera1948,652,948 - 48,663,731 (-)RGD
HuRef1947,934,059 - 47,944,843 (-)ENTREZGENE
CHM1_11951,602,851 - 51,613,631 (-)NCBI
T2T-CHM13v2.01954,186,212 - 54,197,016 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_660275 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH09037 (Get FASTA)   NCBI Sequence Viewer  
  AAP42277 (Get FASTA)   NCBI Sequence Viewer  
  BAF83862 (Get FASTA)   NCBI Sequence Viewer  
  EAW71984 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000390011
  ENSP00000390011.1
GenBank Protein Q7Z7A3 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_660275   ⟸   NM_145232
- UniProtKB: A8K558 (UniProtKB/Swiss-Prot),   Q96GZ7 (UniProtKB/Swiss-Prot),   Q7Z7A3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000390011   ⟸   ENST00000421832

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7Z7A3-F1-model_v2 AlphaFold Q7Z7A3 1-348 view protein structure

Promoters
RGD ID:6795302
Promoter ID:HG_KWN:30675
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_145232
Position:
Human AssemblyChrPosition (strand)Source
Build 361956,303,194 - 56,303,694 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29590 AgrOrtholog
COSMIC CTU1 COSMIC
Ensembl Genes ENSG00000142544 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000421832 ENTREZGENE
  ENST00000421832.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.620 UniProtKB/Swiss-Prot
GTEx ENSG00000142544 GTEx
HGNC ID HGNC:29590 ENTREZGENE
Human Proteome Map CTU1 Human Proteome Map
InterPro CTU1_C UniProtKB/Swiss-Prot
  Ncs6/Tuc1/Ctu1 UniProtKB/Swiss-Prot
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot
  TilS/TtcA_N UniProtKB/Swiss-Prot
  tRNA_thiolation_TtcA_Ctu1 UniProtKB/Swiss-Prot
KEGG Report hsa:90353 UniProtKB/Swiss-Prot
NCBI Gene 90353 ENTREZGENE
OMIM 612694 OMIM
PANTHER ATPASES OF THE PP SUPERFAMILY-RELATED UniProtKB/Swiss-Prot
  PTHR11807:SF12 UniProtKB/Swiss-Prot
Pfam ATP_bind_3 UniProtKB/Swiss-Prot
  zn-ribbon_14 UniProtKB/Swiss-Prot
PharmGKB PA165393368 PharmGKB
PIRSF ATPase_YdaO UniProtKB/Swiss-Prot
Superfamily-SCOP Adenine nucleotide alpha hydrolases-like UniProtKB/Swiss-Prot
UniProt A8K558 ENTREZGENE
  CTU1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q96GZ7 ENTREZGENE
UniProt Secondary A8K558 UniProtKB/Swiss-Prot
  Q96GZ7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-04 CTU1  cytosolic thiouridylase subunit 1    cytosolic thiouridylase subunit 1 homolog (S. pombe)  Symbol and/or name change 5135510 APPROVED