Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | ISO | Nxpe3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of NXPE3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in increased expression of NXPE3 mRNA | CTD | PMID:27840820 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Estradiol] results in increased expression of NXPE3 mRNA | CTD | PMID:32741896 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of NXPE3 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NXPE3 mRNA | CTD | PMID:33387578 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Nxpe3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of NXPE3 gene | CTD | PMID:31683443 | acrolein | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NXPE3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NXPE3 mRNA | CTD | PMID:32699268 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of NXPE3 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | NXPE3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of NXPE3 gene | CTD | PMID:27153756 | aldehydo-D-glucose | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NXPE3 mRNA | CTD | PMID:37567420 | all-trans-retinoic acid | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of NXPE3 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NXPE3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NXPE3 mRNA | CTD | PMID:32699268 | benzo[a]pyrene | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NXPE3 mRNA | CTD | PMID:20106945 more ... | benzo[a]pyrene | decreases methylation | ISO | Nxpe3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of NXPE3 exon and Benzo(a)pyrene results in decreased methylation of NXPE3 intron | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of NXPE3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | NXPE3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of NXPE3 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NXPE3 mRNA | CTD | PMID:30816183 and PMID:32528016 | bortezomib | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of NXPE3 mRNA | CTD | PMID:20977926 | cadmium atom | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NXPE3 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NXPE3 mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | ISO | Nxpe3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NXPE3 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NXPE3 mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of NXPE3 mRNA | CTD | PMID:19320972 | copper(II) sulfate | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of NXPE3 mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of NXPE3 mRNA | CTD | PMID:19167446 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of NXPE3 mRNA | CTD | PMID:26577399 | D-glucose | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NXPE3 mRNA | CTD | PMID:37567420 | dichloroacetic acid | increases expression | ISO | Nxpe3 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of NXPE3 mRNA | CTD | PMID:28962523 | dimethylarsinic acid | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of NXPE3 mRNA | CTD | PMID:34876320 | dioxygen | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of NXPE3 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NXPE3 mRNA | CTD | PMID:29803840 | entinostat | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | entinostat results in increased expression of NXPE3 mRNA | CTD | PMID:27188386 | fructose | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NXPE3 mRNA | CTD | PMID:37567420 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of NXPE3 mRNA | CTD | PMID:27387713 | gadodiamide hydrate | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | gadodiamide results in increased expression of NXPE3 mRNA | CTD | PMID:20959327 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of NXPE3 mRNA | CTD | PMID:33387578 | glucose | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NXPE3 mRNA | CTD | PMID:37567420 | lead(0) | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Lead results in increased expression of NXPE3 mRNA | CTD | PMID:37386098 | mercury dibromide | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of NXPE3 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NXPE3 mRNA | CTD | PMID:27188386 | methylarsonic acid | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of NXPE3 mRNA | CTD | PMID:34876320 | methylmercury chloride | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of NXPE3 mRNA | CTD | PMID:23179753 and PMID:26272509 | methylmercury chloride | decreases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NXPE3 mRNA | CTD | PMID:28001369 | methylmercury chloride | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NXPE3 mRNA | CTD | PMID:27188386 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NXPE3 mRNA | CTD | PMID:25729387 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of NXPE3 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NXPE3 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NXPE3 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of NXPE3 mRNA | CTD | PMID:34911549 | p-chloromercuribenzoic acid | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of NXPE3 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NXPE3 mRNA | CTD | PMID:27188386 | PCB138 | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | phenylmercury acetate | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of NXPE3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NXPE3 mRNA | CTD | PMID:27188386 | SB 431542 | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenate | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of NXPE3 mRNA | CTD | PMID:34876320 | sodium arsenite | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of NXPE3 mRNA | CTD | PMID:25879800 | sodium arsenite | decreases expression | ISO | Nxpe3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NXPE3 mRNA | CTD | PMID:37682722 | sodium arsenite | multiple interactions | ISO | Nxpe3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of NXPE3 mRNA | CTD | PMID:34876320 | temozolomide | decreases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of NXPE3 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Estradiol] results in increased expression of NXPE3 mRNA | CTD | PMID:32741896 | tetrachloroethene | decreases expression | ISO | Nxpe3 (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of NXPE3 mRNA | CTD | PMID:28973375 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of NXPE3 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NXPE3 mRNA | CTD | PMID:25729387 | trichostatin A | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of NXPE3 mRNA | CTD | PMID:24935251 | trichostatin A | multiple interactions | ISO | NXPE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NXPE3 mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of NXPE3 mRNA | CTD | PMID:24935251 and PMID:26272509 | valproic acid | decreases methylation | ISO | NXPE3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NXPE3 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NXPE3 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | NXPE3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NXPE3 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of NXPE3 mRNA | CTD | PMID:23034163 | vorinostat | increases expression | ISO | NXPE3 (Homo sapiens) | 6480464 | vorinostat results in increased expression of NXPE3 mRNA | CTD | PMID:27188386 | |