Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | ACER3 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | PMID:28492532 | intellectual disability | | ISO | ACER3 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Intellectual disability | ClinVar | | Progressive Leukodystrophy, Early Childhood-Onset | | ISO | ACER3 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: LEUKODYSTROPHY more ... | ClinVar | PMID:25741868 more ... | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Analyze GeneStrainQTL List |
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Imported Disease Annotations - CTD
Imported Disease Annotations - OMIM
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
Cellular Component
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Molecular Function
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Molecular Pathway Annotations
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 4. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | SMPDB Annotation Import Pipeline | Pipeline to import SMPDB annotations from SMPDB into RGD |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 7. | Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system. | Wang K, etal., Cell Death Dis. 2016 Mar 3;7:e2124. doi: 10.1038/cddis.2016.36. |
| 8. | Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress. | Wang K, etal., Cell Death Dis. 2020 Jan 16;11(1):28. doi: 10.1038/s41419-019-2214-9. |
| 9. | Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling. | Yin Y, etal., Pathol Res Pract. 2018 Sep;214(9):1381-1387. doi: 10.1016/j.prp.2018.07.029. Epub 2018 Jul 27. |
Additional References at PubMed
| PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:12477932 | PMID:14610273 | PMID:14681479 | PMID:16141072 | PMID:16141073 | PMID:19706712 | PMID:21267068 | PMID:21873635 | PMID:23096701 |
| PMID:26474409 | PMID:29401619 | PMID:32959379 |
Genomics
Comparative Map Data
| Acer3 (Mus musculus - house mouse) |
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| ACER3 (Homo sapiens - human) |
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| Acer3 (Rattus norvegicus - Norway rat) |
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| Acer3 (Chinchilla lanigera - long-tailed chinchilla) |
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| ACER3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ACER3 (Canis lupus familiaris - dog) |
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| Acer3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ACER3 (Sus scrofa - pig) |
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| ACER3 (Chlorocebus sabaeus - green monkey) |
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| Acer3 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Acer3
3589 total Variants 
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