Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | affects expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ZFTRAF1 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFTRAF1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:21215274 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ZFTRAF1 mRNA | CTD | PMID:20188158 | 3-chloropropane-1,2-diol | increases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of ZFTRAF1 protein | CTD | PMID:34915118 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZFTRAF1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:36041667 | acetamide | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ZFTRAF1 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ZFTRAF1 mRNA | CTD | PMID:23724009 | aristolochic acid A | increases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ZFTRAF1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZFTRAF1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZFTRAF1 gene | CTD | PMID:25304211 | benzo[a]pyrene | increases methylation | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZFTRAF1 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:22228805 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ZFTRAF1 protein | CTD | PMID:31163220 | bisphenol A | multiple interactions | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZFTRAF1 mRNA | CTD | PMID:28628672 | bisphenol A | multiple interactions | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ZFTRAF1 protein | CTD | PMID:33376534 | bisphenol A | increases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ZFTRAF1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:32528016 | bisphenol A | affects expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ZFTRAF1 mRNA | CTD | PMID:30816183 and PMID:34947998 | bisphenol F | multiple interactions | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:36041667 | cadmium atom | increases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Cadmium results in increased expression of ZFTRAF1 mRNA | CTD | PMID:24376830 | carbon nanotube | affects expression | EXP | | 6480464 | Nanotubes and Carbon affects the expression of ZFTRAF1 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of ZFTRAF1 mRNA | CTD | PMID:25620056 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:17585979 and PMID:23811191 | clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ZFTRAF1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ZFTRAF1 mRNA] | CTD | PMID:17585979 | copper(II) sulfate | decreases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:19549813 | dexamethasone | multiple interactions | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZFTRAF1 mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:21266533 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of ZFTRAF1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of ZFTRAF1 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:22206623 | fulvestrant | increases methylation | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of ZFTRAF1 gene | CTD | PMID:31601247 | hydrogen cyanide | decreases expression | EXP | | 6480464 | Hydrogen Cyanide results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:33914522 | indole-3-methanol | affects expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of ZFTRAF1 mRNA | CTD | PMID:21396975 | indometacin | multiple interactions | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZFTRAF1 mRNA | CTD | PMID:28628672 | menadione | affects expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ZFTRAF1 mRNA | CTD | PMID:20044591 | methyl methanesulfonate | increases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ZFTRAF1 mRNA | CTD | PMID:23649840 | nickel atom | decreases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:23195993 and PMID:25583101 | ozone | multiple interactions | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of CYHR1 mRNA | CTD | PMID:35430440 | paracetamol | increases expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ZFTRAF1 mRNA | CTD | PMID:22230336 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ZFTRAF1 mRNA | CTD | PMID:17562736 | paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ZFTRAF1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ZFTRAF1 mRNA] | CTD | PMID:17585979 | paraquat | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:32680482 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ZFTRAF1 mRNA | CTD | PMID:17426115 | potassium cyanide | increases expression | EXP | | 6480464 | Potassium Cyanide results in increased expression of ZFTRAF1 mRNA | CTD | PMID:33914522 | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of ZFTRAF1 mRNA | CTD | PMID:23557933 | selenomethionine | affects expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Selenomethionine affects the expression of ZFTRAF1 mRNA | CTD | PMID:17222674 | Soman | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:19281266 | testosterone enanthate | affects expression | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of ZFTRAF1 mRNA | CTD | PMID:17440010 | thioacetamide | decreases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ZFTRAF1 mRNA | CTD | PMID:34492290 | triphenyl phosphate | increases expression | ISO | Zftraf1 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of ZFTRAF1 mRNA | CTD | PMID:30589522 | valproic acid | increases methylation | ISO | ZFTRAF1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ZFTRAF1 gene | CTD | PMID:29154799 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ZFTRAF1 mRNA | CTD | PMID:17963808 | |