Pik3r4 (phosphoinositide-3-kinase regulatory subunit 4) - Rat Genome Database

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Gene: Pik3r4 (phosphoinositide-3-kinase regulatory subunit 4) Mus musculus
Analyze
Symbol: Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
RGD ID: 1557573
MGI Page MGI
Description: Predicted to enable protein serine/threonine kinase activity. Involved in cellular response to glucose starvation. Located in axoneme. Part of phosphatidylinositol 3-kinase complex, class III. Is expressed in central nervous system; embryo; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Orthologous to human PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2210010O15Rik; C730038E05Rik; C85833; D9Ertd418e; p15; p150; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150; phosphoinositide 3-kinase regulatory subunit 4; PI3-kinase regulatory subunit 4; Vp; Vps15
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,520,156 - 105,564,854 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9105,520,177 - 105,564,856 (+)EnsemblGRCm39 Ensembl
GRCm389105,642,995 - 105,687,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,642,978 - 105,687,657 (+)EnsemblGRCm38mm10GRCm38
MGSCv379105,545,325 - 105,589,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369105,501,078 - 105,545,755 (+)NCBIMGSCv36mm8
Celera9105,236,861 - 105,284,774 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15226823   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16467569  
PMID:18799693   PMID:20114047   PMID:21267068   PMID:21873635   PMID:23332761   PMID:23630012   PMID:24089209   PMID:24705551   PMID:26387534   PMID:28378742   PMID:29311744   PMID:30952952  
PMID:32093570   PMID:32325033   PMID:34428398   PMID:37414850  


Genomics

Comparative Map Data
Pik3r4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,520,156 - 105,564,854 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9105,520,177 - 105,564,856 (+)EnsemblGRCm39 Ensembl
GRCm389105,642,995 - 105,687,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,642,978 - 105,687,657 (+)EnsemblGRCm38mm10GRCm38
MGSCv379105,545,325 - 105,589,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369105,501,078 - 105,545,755 (+)NCBIMGSCv36mm8
Celera9105,236,861 - 105,284,774 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.79NCBI
PIK3R4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383130,678,934 - 130,746,829 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3130,678,934 - 130,746,829 (-)EnsemblGRCh38hg38GRCh38
GRCh373130,397,778 - 130,465,673 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363131,880,468 - 131,948,386 (-)NCBINCBI36Build 36hg18NCBI36
Build 343131,880,475 - 131,948,348NCBI
Celera3128,823,051 - 128,890,972 (-)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3127,782,400 - 127,850,320 (-)NCBIHuRef
CHM1_13130,360,774 - 130,428,689 (-)NCBICHM1_1
T2T-CHM13v2.03133,422,776 - 133,490,673 (-)NCBIT2T-CHM13v2.0
Pik3r4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,146,660 - 115,195,326 (+)NCBIGRCr8
mRatBN7.28106,267,908 - 106,316,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,267,954 - 106,316,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8111,890,314 - 111,939,993 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,089,590 - 110,139,269 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08107,932,278 - 107,981,958 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08114,300,248 - 114,350,686 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8114,300,257 - 114,350,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08113,675,758 - 113,725,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48110,741,833 - 110,790,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18110,762,479 - 110,809,819 (+)NCBI
Celera8105,594,747 - 105,643,191 (+)NCBICelera
Cytogenetic Map8q32NCBI
Pik3r4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555017,604,501 - 7,681,947 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555017,604,934 - 7,681,947 (+)NCBIChiLan1.0ChiLan1.0
PIK3R4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22128,607,846 - 128,710,837 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13128,621,885 - 128,714,033 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03127,743,873 - 127,834,512 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13135,089,584 - 135,157,193 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3135,089,584 - 135,157,193 (-)Ensemblpanpan1.1panPan2
PIK3R4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12327,902,500 - 27,973,609 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2327,902,840 - 27,971,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2327,876,020 - 27,947,053 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02328,409,021 - 28,480,487 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2328,409,029 - 28,480,489 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12328,103,972 - 28,175,361 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02328,158,914 - 28,236,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02328,414,452 - 28,485,590 (-)NCBIUU_Cfam_GSD_1.0
Pik3r4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560267,401,776 - 67,472,004 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365294,162,112 - 4,232,510 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365294,162,276 - 4,232,471 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3R4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,731,023 - 1,815,556 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,730,988 - 1,815,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2131,388,518 - 1,533,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3R4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11559,444,570 - 59,515,619 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1559,444,616 - 59,515,240 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604132,468,967 - 32,542,919 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3r4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247306,642,190 - 6,744,470 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247306,642,195 - 6,744,480 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pik3r4
1678 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:111
Interacting mature miRNAs:120
Transcripts:ENSMUST00000065778
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse

Markers in Region
C85833  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389105,687,259 - 105,687,550UniSTSGRCm38
MGSCv379105,589,589 - 105,589,880UniSTSGRCm37
Celera9105,284,380 - 105,284,671UniSTS
Cytogenetic Map9F1UniSTS
cM Map956.0UniSTS
Whitehead/MRC_RH91097.91UniSTS
D9Dcr82  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389105,645,533 - 105,645,642UniSTSGRCm38
MGSCv379105,547,863 - 105,547,972UniSTSGRCm37
Cytogenetic Map9F1UniSTS
cM Map9 UniSTS
RH126920  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389105,687,370 - 105,687,618UniSTSGRCm38
MGSCv379105,589,700 - 105,589,948UniSTSGRCm37
Celera9105,284,491 - 105,284,738UniSTS
Cytogenetic Map9F1UniSTS
cM Map956.0UniSTS
Whitehead/MRC_RH91097.06UniSTS
UniSTS:224392  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389105,675,011 - 105,675,178UniSTSGRCm38
MGSCv379105,577,341 - 105,577,508UniSTSGRCm37
Celera9105,255,335 - 105,255,506UniSTS
Celera9105,269,834 - 105,270,005UniSTS
Cytogenetic Map9F1UniSTS
cM Map956.0UniSTS
MARC_17559-17560:1030455059:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389105,669,026 - 105,669,833UniSTSGRCm38
MGSCv379105,571,356 - 105,572,163UniSTSGRCm37
Celera9105,263,852 - 105,264,659UniSTS
Cytogenetic Map9F1UniSTS
cM Map956.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC157947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC158047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000065778   ⟹   ENSMUSP00000067400
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,369 - 105,564,856 (+)Ensembl
GRCm38.p6 Ensembl9105,643,170 - 105,687,657 (+)Ensembl
RefSeq Acc Id: ENSMUST00000186943   ⟹   ENSMUSP00000140311
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,535,588 - 105,546,198 (+)Ensembl
GRCm38.p6 Ensembl9105,658,389 - 105,668,999 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187446
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,214 - 105,541,015 (+)Ensembl
GRCm38.p6 Ensembl9105,643,015 - 105,663,816 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,177 - 105,556,519 (+)Ensembl
GRCm38.p6 Ensembl9105,642,978 - 105,679,320 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188385
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,538,362 - 105,540,554 (+)Ensembl
GRCm38.p6 Ensembl9105,661,163 - 105,663,355 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188784   ⟹   ENSMUSP00000140988
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,400 - 105,526,195 (+)Ensembl
GRCm38.p6 Ensembl9105,643,201 - 105,648,996 (+)Ensembl
RefSeq Acc Id: ENSMUST00000189691
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,558,909 - 105,563,593 (+)Ensembl
GRCm38.p6 Ensembl9105,681,710 - 105,686,394 (+)Ensembl
RefSeq Acc Id: ENSMUST00000190358   ⟹   ENSMUSP00000139643
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,180 - 105,521,958 (+)Ensembl
GRCm38.p6 Ensembl9105,642,981 - 105,644,759 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,207 - 105,532,889 (+)Ensembl
GRCm38.p6 Ensembl9105,643,008 - 105,655,690 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191268   ⟹   ENSMUSP00000139427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,520,229 - 105,564,730 (+)Ensembl
GRCm38.p6 Ensembl9105,643,030 - 105,687,531 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214254
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9105,558,992 - 105,564,848 (+)Ensembl
GRCm38.p6 Ensembl9105,681,793 - 105,687,649 (+)Ensembl
RefSeq Acc Id: NM_001081309   ⟹   NP_001074778
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399105,520,194 - 105,564,854 (+)NCBI
GRCm389105,642,995 - 105,687,655 (+)ENTREZGENE
MGSCv379105,545,325 - 105,589,985 (+)RGD
Celera9105,236,861 - 105,284,774 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036155370   ⟹   XP_036011263
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399105,520,156 - 105,564,849 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001074778   ⟸   NM_001081309
- UniProtKB: Q8C9D7 (UniProtKB/Swiss-Prot),   Q8C948 (UniProtKB/Swiss-Prot),   Q56A65 (UniProtKB/Swiss-Prot),   Q9CVC5 (UniProtKB/Swiss-Prot),   Q8VD65 (UniProtKB/Swiss-Prot),   B2RXR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000067400   ⟸   ENSMUST00000065778
RefSeq Acc Id: ENSMUSP00000140311   ⟸   ENSMUST00000186943
RefSeq Acc Id: ENSMUSP00000139427   ⟸   ENSMUST00000191268
RefSeq Acc Id: ENSMUSP00000139643   ⟸   ENSMUST00000190358
RefSeq Acc Id: ENSMUSP00000140988   ⟸   ENSMUST00000188784
RefSeq Acc Id: XP_036011263   ⟸   XM_036155370
- Peptide Label: isoform X1
- UniProtKB: B2RXR2 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VD65-F1-model_v2 AlphaFold Q8VD65 1-1358 view protein structure

Promoters
RGD ID:6844951
Promoter ID:MM_KWN:58630
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001081309,   UC009RIM.1,   UC009RIN.1,   UC009RIO.1,   UC009RIQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369105,545,109 - 105,545,609 (+)MPROMDB
RGD ID:8670692
Promoter ID:EPDNEW_M13375
Type:initiation region
Name:Pik3r4_1
Description:Mus musculus phosphoinositide-3-kinase regulatory subunit 4 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389105,643,008 - 105,643,068EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922919 AgrOrtholog
Ensembl Genes ENSMUSG00000032571 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000065778 ENTREZGENE
  ENSMUST00000065778.13 UniProtKB/Swiss-Prot
  ENSMUST00000186943.2 UniProtKB/TrEMBL
  ENSMUST00000188784.2 UniProtKB/TrEMBL
  ENSMUST00000190358.2 UniProtKB/TrEMBL
  ENSMUST00000191268.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEAT_type_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vps15-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75669 UniProtKB/Swiss-Prot
MGD MGI:1922919 ENTREZGENE
NCBI Gene 75669 ENTREZGENE
PANTHER PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR17583 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pik3r4 PhenoGen
PROSITE HEAT_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WP62_MOUSE UniProtKB/TrEMBL
  A0A087WQR4_MOUSE UniProtKB/TrEMBL
  A0A0R4J2C7_MOUSE UniProtKB/TrEMBL
  B2RXR2 ENTREZGENE, UniProtKB/TrEMBL
  B2RY05_MOUSE UniProtKB/TrEMBL
  PI3R4_MOUSE UniProtKB/Swiss-Prot
  Q56A65 ENTREZGENE
  Q8C948 ENTREZGENE
  Q8C9D7 ENTREZGENE
  Q8VD65 ENTREZGENE
  Q9CVC5 ENTREZGENE
UniProt Secondary Q56A65 UniProtKB/Swiss-Prot
  Q8C948 UniProtKB/Swiss-Prot
  Q8C9D7 UniProtKB/Swiss-Prot
  Q9CVC5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-09 Pik3r4  phosphoinositide-3-kinase regulatory subunit 4    phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150  Symbol and/or name change 5135510 APPROVED