Or2a57 (olfactory receptor family 2 subfamily A member 57) - Rat Genome Database

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Gene: Or2a57 (olfactory receptor family 2 subfamily A member 57) Mus musculus
Analyze
No known orthologs.
Symbol: Or2a57
Name: olfactory receptor family 2 subfamily A member 57
RGD ID: 1553349
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR2A1 (olfactory receptor family 2 subfamily A member 1) and OR2A42 (olfactory receptor family 2 subfamily A member 42).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2P3E9-4322325-4321360; IB1; IB12; MOR261; MOR261-9; olfactory receptor 47; olfactory receptor MOR261-9; Olfr13; Olfr47
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39643,212,544 - 43,213,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl643,208,463 - 43,213,893 (+)EnsemblGRCm39 Ensembl
GRCm38643,235,610 - 43,236,575 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl643,231,529 - 43,236,959 (+)EnsemblGRCm38mm10GRCm38
MGSCv37643,185,609 - 43,186,574 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36643,165,217 - 43,166,182 (+)NCBIMGSCv36mm8
Celera643,183,523 - 43,184,488 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map621.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9875846   PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:16805845   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or2a57
31 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:56
Interacting mature miRNAs:56
Transcripts:ENSMUST00000078057
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse

Markers in Region
UniSTS:495340  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38643,235,578 - 43,236,636UniSTSGRCm38
MGSCv37643,185,577 - 43,186,635UniSTSGRCm37
Celera643,183,491 - 43,184,549UniSTS
Cytogenetic Map6B2.1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000078057   ⟹   ENSMUSP00000077204
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl643,212,512 - 43,213,570 (+)Ensembl
GRCm38.p6 Ensembl643,235,578 - 43,236,636 (+)Ensembl
RefSeq Acc Id: ENSMUST00000215569   ⟹   ENSMUSP00000151056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl643,208,463 - 43,213,893 (+)Ensembl
GRCm38.p6 Ensembl643,231,529 - 43,236,959 (+)Ensembl
RefSeq Acc Id: NM_146370   ⟹   NP_666482
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39643,212,544 - 43,213,509 (+)NCBI
GRCm38643,235,610 - 43,236,575 (+)ENTREZGENE
MGSCv37643,185,609 - 43,186,574 (+)RGD
Celera643,183,523 - 43,184,488 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_666482   ⟸   NM_146370
- UniProtKB: Q8VF18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000151056   ⟸   ENSMUST00000215569
RefSeq Acc Id: ENSMUSP00000077204   ⟸   ENSMUST00000078057
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VF18-F1-model_v2 AlphaFold Q8VF18 1-321 view protein structure

Promoters
RGD ID:6889548
Promoter ID:EPDNEW_M8225
Type:multiple initiation site
Name:Olfr47_1
Description:Mus musculus olfactory receptor 47 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38643,235,692 - 43,235,752EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1333821 AgrOrtholog
Ensembl Genes ENSMUSG00000061210 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078057 ENTREZGENE
  ENSMUST00000078057.4 UniProtKB/TrEMBL
  ENSMUST00000215569.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:18346 UniProtKB/TrEMBL
MGD MGI:1333821 ENTREZGENE
NCBI Gene 18346 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2a57 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VF18 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z1V2_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or2a57  olfactory receptor family 2 subfamily A member 57  Olfr47  olfactory receptor 47  Symbol and/or name change 5135510 APPROVED