Txlnb (taxilin beta) - Rat Genome Database

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Gene: Txlnb (taxilin beta) Mus musculus
Analyze
Symbol: Txlnb
Name: taxilin beta
RGD ID: 1553268
MGI Page MGI
Description: Predicted to enable syntaxin binding activity. Predicted to be located in cytoplasm. Is expressed in dorsal root ganglion; glossopharyngeal ganglion; medulla oblongata basal plate mantle layer; trigeminal ganglion; and ventral grey horn. Orthologous to human TXLNB (taxilin beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2310001N14Rik; beta-taxilin; Mdp7; Mdp77; muscle specific protein; muscle-derived protein 77
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391017,671,967 - 17,721,411 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1017,671,974 - 17,721,413 (+)EnsemblGRCm39 Ensembl
GRCm381017,796,219 - 17,845,663 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1017,796,226 - 17,845,665 (+)EnsemblGRCm38mm10GRCm38
MGSCv371017,516,025 - 17,565,469 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361017,485,696 - 17,535,079 (+)NCBIMGSCv36mm8
Celera1017,679,390 - 17,728,131 (+)NCBICelera
Cytogenetic Map10A2NCBI
cM Map107.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11805063   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:27231216   PMID:32325033  


Genomics

Comparative Map Data
Txlnb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391017,671,967 - 17,721,411 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1017,671,974 - 17,721,413 (+)EnsemblGRCm39 Ensembl
GRCm381017,796,219 - 17,845,663 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1017,796,226 - 17,845,665 (+)EnsemblGRCm38mm10GRCm38
MGSCv371017,516,025 - 17,565,469 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361017,485,696 - 17,535,079 (+)NCBIMGSCv36mm8
Celera1017,679,390 - 17,728,131 (+)NCBICelera
Cytogenetic Map10A2NCBI
cM Map107.24NCBI
TXLNB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386139,159,162 - 139,323,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6139,240,061 - 139,291,998 (-)EnsemblGRCh38hg38GRCh38
GRCh376139,561,198 - 139,613,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366139,602,891 - 139,654,849 (-)NCBINCBI36Build 36hg18NCBI36
Build 346139,602,893 - 139,654,849NCBI
Celera6140,301,267 - 140,353,271 (-)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6137,122,735 - 137,174,737 (-)NCBIHuRef
CHM1_16139,824,342 - 139,876,297 (-)NCBICHM1_1
T2T-CHM13v2.06140,347,705 - 140,507,844 (-)NCBIT2T-CHM13v2.0
Txlnb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8114,224,647 - 14,269,837 (+)NCBIGRCr8
mRatBN7.2112,404,845 - 12,449,977 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl112,404,859 - 12,449,975 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx112,167,527 - 12,213,188 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0118,169,452 - 18,215,113 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0112,385,196 - 12,430,312 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0112,915,781 - 12,961,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl112,915,734 - 12,961,670 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0114,609,469 - 14,655,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4112,814,809 - 12,857,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1112,753,057 - 12,856,515 (+)NCBI
Celera110,862,671 - 10,907,830 (+)NCBICelera
Cytogenetic Map1p12NCBI
Txlnb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543620,445,205 - 20,482,523 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543620,442,605 - 20,481,758 (+)NCBIChiLan1.0ChiLan1.0
TXLNB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25159,208,553 - 159,293,118 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16157,102,881 - 157,186,505 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06137,002,343 - 137,086,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16141,083,798 - 141,133,794 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6141,084,075 - 141,130,691 (-)Ensemblpanpan1.1panPan2
TXLNB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1131,417,182 - 31,464,674 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl131,417,538 - 31,464,624 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,288,265 - 32,338,086 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0131,575,856 - 31,625,741 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl131,575,904 - 31,625,667 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1131,451,654 - 31,501,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0131,334,143 - 31,384,048 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0131,645,609 - 31,695,514 (-)NCBIUU_Cfam_GSD_1.0
Txlnb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946126,472,022 - 126,513,407 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365606,251,213 - 6,292,598 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365606,253,195 - 6,292,556 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TXLNB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,228,615 - 25,285,301 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,228,602 - 25,285,303 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,367,688 - 28,425,410 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TXLNB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11334,099,200 - 34,151,823 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1334,099,435 - 34,151,823 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660406,241,641 - 6,291,264 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Txlnb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475314,712,569 - 14,761,243 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475314,712,618 - 14,759,830 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Txlnb
1562 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:748
Count of miRNA genes:499
Interacting mature miRNAs:566
Transcripts:ENSMUST00000037964, ENSMUST00000175676
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532725Sluc44b_msusceptibility to lung cancer 44b (mouse)10126289265Mouse
11532724Sluc44c_msusceptibility to lung cancer 44c (mouse)10126289265Mouse
11532723Sluc44d_msusceptibility to lung cancer 44d (mouse)10126289265Mouse
11532722Sluc44e_msusceptibility to lung cancer 44e (mouse)10126289265Mouse
11532721Sluc44_msusceptibility to lung cancer 44 (mouse)10126289265Mouse
11532720Sluc44a_msusceptibility to lung cancer 44a (mouse)10126289265Mouse
11532718Sluc44f_msusceptibility to lung cancer 44f (mouse)10126289265Mouse
11532717Sluc44g_msusceptibility to lung cancer 44g (mouse)10126289265Mouse
11533917Mts2_mmammary tumor susceptibility 2 (mouse)10126289265Mouse
1300759Geot_mgeotaxia (mouse)Not determined10126289265Mouse
1300881Sluc29_msusceptibility to lung cancer 29 (mouse)Not determined10126289265Mouse
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10440815438408276Mouse
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
1301796Mop2_mmorphine preference 2 (mouse)Not determined10928911929028424Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
13208570Bmiq9_mbody mass index QTL 9 (mouse)101287574424875898Mouse
1558857Igan1_mIgA nephropathy 1 (mouse)Not determined101771831329704155Mouse

Markers in Region
D10Mit50  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381017,842,565 - 17,842,708UniSTSGRCm38
MGSCv371017,562,371 - 17,562,514UniSTSGRCm37
Celera1017,725,031 - 17,725,176UniSTS
Cytogenetic Map10A2UniSTS
cM Map107.0UniSTS
Whitehead Genetic104.4UniSTS
Whitehead_YAC10 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000037964   ⟹   ENSMUSP00000044936
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1017,672,004 - 17,721,413 (+)Ensembl
GRCm38.p6 Ensembl1017,796,256 - 17,845,665 (+)Ensembl
RefSeq Acc Id: ENSMUST00000175676
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1017,671,974 - 17,683,656 (+)Ensembl
GRCm38.p6 Ensembl1017,796,226 - 17,807,908 (+)Ensembl
RefSeq Acc Id: NM_138628   ⟹   NP_619534
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391017,671,967 - 17,721,411 (+)NCBI
GRCm381017,796,219 - 17,845,663 (+)NCBI
MGSCv371017,516,025 - 17,565,469 (+)RGD
Celera1017,679,390 - 17,728,131 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_619534   ⟸   NM_138628
- UniProtKB: Q3UVB8 (UniProtKB/Swiss-Prot),   B2RU93 (UniProtKB/Swiss-Prot),   Q8BUK2 (UniProtKB/Swiss-Prot),   Q8VBT1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000044936   ⟸   ENSMUST00000037964

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VBT1-F1-model_v2 AlphaFold Q8VBT1 1-685 view protein structure

Promoters
RGD ID:6820064
Promoter ID:MM_KWN:3601
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:NM_138628
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361017,515,954 - 17,516,454 (+)MPROMDB
RGD ID:8671538
Promoter ID:EPDNEW_M13800
Type:initiation region
Name:Txlnb_1
Description:Mus musculus taxilin beta , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381017,796,326 - 17,796,386EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2671945 AgrOrtholog
Ensembl Genes ENSMUSG00000039891 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000037964 ENTREZGENE
  ENSMUST00000037964.7 UniProtKB/Swiss-Prot
InterPro Taxilin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:378431 UniProtKB/Swiss-Prot
MGD MGI:2671945 ENTREZGENE
NCBI Gene 378431 ENTREZGENE
PANTHER BETA-TAXILIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16127 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Taxilin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Txlnb PhenoGen
UniProt B2RU93 ENTREZGENE
  Q3UVB8 ENTREZGENE
  Q8BUK2 ENTREZGENE
  Q8BWJ7_MOUSE UniProtKB/TrEMBL
  Q8VBT1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RU93 UniProtKB/Swiss-Prot
  Q3UVB8 UniProtKB/Swiss-Prot
  Q8BUK2 UniProtKB/Swiss-Prot