1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of PCSK6 mRNA CTD PMID:22206623 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of PCSK6 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of PCSK6 mRNA CTD PMID:12655037 and PMID:17557909 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PCSK6 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PCSK6 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of PCSK6 mRNA and [Progesterone co-treated with Estradiol] results in increased expression of PCSK6 mRNA CTD PMID:17404688 and PMID:20660070 17beta-estradiol increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Estradiol results in increased expression of PCSK6 mRNA CTD PMID:32145629 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO PCSK6 (Homo sapiens) 6480464 2 more ... CTD PMID:23146750 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PCSK6 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PCSK6 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PCSK6 mRNA CTD PMID:32553695 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PCSK6 mRNA CTD PMID:24680724 and PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PCSK6 mRNA CTD PMID:17035482 2,4-dinitrotoluene affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of PCSK6 mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression ISO PCSK6 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of PCSK6 mRNA CTD PMID:30851411 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO PCSK6 (Homo sapiens) 6480464 3 more ... CTD PMID:23146750 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PCSK6 mRNA CTD PMID:20188158 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of PCSK6 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine multiple interactions ISO PCSK6 (Homo sapiens) 6480464 Decitabine inhibits the reaction [Smoke results in decreased expression of PCSK6 mRNA] CTD PMID:21095227 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Omeprazole affects the expression of PCSK6 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Propylthiouracil affects the expression of PCSK6 mRNA CTD PMID:19483382 6-propyl-2-thiouracil decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of PCSK6 mRNA CTD PMID:24780913 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:32553695 acetamide decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 acetamide results in decreased expression of PCSK6 mRNA CTD PMID:31881176 acrylamide decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of PCSK6 mRNA CTD PMID:28959563 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of PCSK6 mRNA CTD PMID:19770486 aflatoxin B1 affects expression ISO PCSK6 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of PCSK6 protein CTD PMID:20106945 alachlor increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 alachlor results in increased expression of PCSK6 mRNA CTD PMID:12419858 amiodarone affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Amiodarone affects the expression of PCSK6 mRNA CTD PMID:19483382 ammonium chloride affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of PCSK6 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO PCSK6 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of PCSK6 mRNA CTD PMID:24449571 arsane affects methylation ISO PCSK6 (Homo sapiens) 6480464 Arsenic affects the methylation of PCSK6 gene CTD PMID:25304211 arsane multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of PCSK6 mRNA CTD PMID:32525701 arsenic atom affects methylation ISO PCSK6 (Homo sapiens) 6480464 Arsenic affects the methylation of PCSK6 gene CTD PMID:25304211 arsenic atom multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of PCSK6 mRNA CTD PMID:32525701 atrazine affects methylation ISO Pcsk6 (Rattus norvegicus) 6480464 Atrazine affects the methylation of PCSK6 gene CTD PMID:35440735 benzbromarone affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Benzbromarone affects the expression of PCSK6 mRNA CTD PMID:19483382 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene metabolite results in decreased expression of PCSK6 mRNA and Benzo(a)pyrene results in decreased expression of PCSK6 mRNA CTD PMID:21715664 and PMID:32553695 benzo[a]pyrene affects methylation ISO PCSK6 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PCSK6 intron CTD PMID:30157460 benzo[a]pyrene decreases methylation ISO PCSK6 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of PCSK6 promoter CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PCSK6 mRNA CTD PMID:25908611 benzo[a]pyrene decreases expression ISO PCSK6 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PCSK6 mRNA CTD PMID:20064835 more ... benzo[e]pyrene increases methylation ISO PCSK6 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of PCSK6 intron CTD PMID:30157460 bisphenol A affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 bisphenol A affects the expression of PCSK6 mRNA CTD PMID:25181051 bisphenol A increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of PCSK6 mRNA CTD PMID:32145629 bisphenol A decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of PCSK6 mRNA CTD PMID:30816183 butanal decreases expression ISO PCSK6 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of PCSK6 mRNA CTD PMID:26079696 calcitriol multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of PCSK6 mRNA CTD PMID:21592394 calcitriol decreases expression ISO PCSK6 (Homo sapiens) 6480464 Calcitriol results in decreased expression of PCSK6 mRNA CTD PMID:21592394 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PCSK6 mRNA CTD PMID:20938992 chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of PCSK6 mRNA CTD PMID:28472532 cisplatin multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of PCSK6 mRNA CTD PMID:27392435 cisplatin decreases expression ISO PCSK6 (Homo sapiens) 6480464 Cisplatin results in decreased expression of PCSK6 mRNA CTD PMID:27392435 clofibrate affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Clofibrate affects the expression of PCSK6 mRNA CTD PMID:19483382 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of PCSK6 mRNA CTD PMID:17585979 copper(II) sulfate decreases expression ISO PCSK6 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of PCSK6 mRNA CTD PMID:19549813 coumestrol multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 coumestrol decreases expression ISO PCSK6 (Homo sapiens) 6480464 Coumestrol results in decreased expression of PCSK6 mRNA CTD PMID:19167446 cyclosporin A decreases expression ISO PCSK6 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PCSK6 mRNA CTD PMID:20106945 DDT increases methylation ISO Pcsk6 (Rattus norvegicus) 6480464 DDT results in increased methylation of PCSK6 gene CTD PMID:31682807 diethylstilbestrol increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of PCSK6 mRNA CTD PMID:17005392 diuron decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Diuron results in decreased expression of PCSK6 mRNA CTD PMID:25152437 dorsomorphin multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCSK6 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO PCSK6 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PCSK6 mRNA CTD PMID:29803840 endosulfan increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of PCSK6 mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PCSK6 mRNA CTD PMID:19167446 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PCSK6 mRNA CTD PMID:30319688 flutamide increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Flutamide results in increased expression of PCSK6 mRNA CTD PMID:24136188 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PCSK6 mRNA CTD PMID:20938992 inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PCSK6 mRNA CTD PMID:36331819 L-ethionine affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Ethionine affects the expression of PCSK6 mRNA CTD PMID:19483382 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PCSK6 mRNA CTD PMID:20938992 leflunomide increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 leflunomide results in increased expression of PCSK6 mRNA CTD PMID:24136188 mercury dichloride increases expression ISO PCSK6 (Homo sapiens) 6480464 Mercuric Chloride results in increased expression of PCSK6 mRNA CTD PMID:27188386 methapyrilene increases methylation ISO PCSK6 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of PCSK6 intron CTD PMID:30157460 methoxychlor affects methylation ISO Pcsk6 (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of PCSK6 gene CTD PMID:35440735 N-nitrosodiethylamine multiple interactions ISO Pcsk6 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PCSK6 mRNA CTD PMID:20360939 nefazodone increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 nefazodone results in increased expression of PCSK6 mRNA CTD PMID:24136188 omeprazole affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Omeprazole affects the expression of PCSK6 mRNA CTD PMID:19483382 p-toluidine increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 4-toluidine results in increased expression of PCSK6 mRNA CTD PMID:27638505 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of PCSK6 mRNA CTD PMID:17562736 paracetamol decreases expression ISO PCSK6 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PCSK6 mRNA CTD PMID:29067470 perfluorohexanesulfonic acid decreases expression EXP 6480464 perfluorohexanesulfonic acid results in decreased expression of PCSK6 mRNA CTD PMID:37995155 perfluorononanoic acid decreases expression ISO PCSK6 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of PCSK6 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of PCSK6 mRNA CTD PMID:18692542 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PCSK6 mRNA CTD PMID:36331819 phenethyl caffeate multiple interactions ISO Pcsk6 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PCSK6 mRNA CTD PMID:20360939 phenobarbital affects expression ISO PCSK6 (Homo sapiens) 6480464 Phenobarbital affects the expression of PCSK6 mRNA CTD PMID:19159669 phenylephrine increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Phenylephrine results in increased expression of PCSK6 mRNA CTD PMID:18158353 pirinixic acid affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 pirinixic acid affects the expression of PCSK6 mRNA CTD PMID:19483382 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PCSK6 mRNA CTD PMID:23811191 pirinixic acid decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 pirinixic acid results in decreased expression of PCSK6 mRNA CTD PMID:19162173 progesterone multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of PCSK6 mRNA and [Progesterone co-treated with Estradiol] results in increased expression of PCSK6 mRNA CTD PMID:17404688 and PMID:20660070 progesterone increases expression ISO PCSK6 (Homo sapiens) 6480464 Progesterone results in increased expression of PCSK6 mRNA CTD PMID:17404688 and PMID:18070364 propanal decreases expression ISO PCSK6 (Homo sapiens) 6480464 propionaldehyde results in decreased expression of PCSK6 mRNA CTD PMID:26079696 rac-lactic acid decreases expression ISO PCSK6 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of PCSK6 mRNA CTD PMID:30851411 resveratrol multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of PCSK6 mRNA CTD PMID:19167446 rotenone decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of PCSK6 mRNA CTD PMID:28374803 SB 431542 multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCSK6 mRNA CTD PMID:27188386 silicon dioxide decreases expression ISO PCSK6 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PCSK6 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO PCSK6 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of PCSK6 mRNA CTD PMID:23806026 sodium arsenate multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of PCSK6 mRNA CTD PMID:32525701 sodium arsenite increases expression ISO PCSK6 (Homo sapiens) 6480464 sodium arsenite results in increased expression of PCSK6 mRNA CTD PMID:34032870 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PCSK6 mRNA CTD PMID:37682722 sodium dodecyl sulfate increases expression ISO PCSK6 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of PCSK6 mRNA CTD PMID:31734321 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of PCSK6 mRNA CTD PMID:27862939 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of PCSK6 mRNA CTD PMID:25123088 testosterone multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of PCSK6 mRNA CTD PMID:21592394 testosterone decreases expression ISO PCSK6 (Homo sapiens) 6480464 Testosterone results in decreased expression of PCSK6 mRNA CTD PMID:21592394 thioacetamide affects expression ISO Pcsk6 (Rattus norvegicus) 6480464 Thioacetamide affects the expression of PCSK6 mRNA CTD PMID:19483382 thioacetamide decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of PCSK6 mRNA CTD PMID:34492290 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of PCSK6 mRNA CTD PMID:23557971 triclosan increases expression ISO PCSK6 (Homo sapiens) 6480464 Triclosan results in increased expression of PCSK6 mRNA CTD PMID:30510588 triphenyl phosphate increases expression ISO Pcsk6 (Rattus norvegicus) 6480464 triphenyl phosphate results in increased expression of PCSK6 mRNA CTD PMID:30589522 troglitazone decreases expression ISO PCSK6 (Homo sapiens) 6480464 troglitazone results in decreased expression of PCSK6 mRNA CTD PMID:25572481 trovafloxacin decreases expression ISO Pcsk6 (Rattus norvegicus) 6480464 trovafloxacin results in decreased expression of PCSK6 mRNA CTD PMID:24136188 valproic acid increases methylation ISO PCSK6 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of PCSK6 gene CTD PMID:29154799 valproic acid multiple interactions ISO PCSK6 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCSK6 mRNA CTD PMID:27188386 valproic acid increases expression ISO PCSK6 (Homo sapiens) 6480464 Valproic Acid results in increased expression of PCSK6 mRNA CTD PMID:24383497 and PMID:26272509 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of PCSK6 mRNA CTD PMID:18930951 
