E2f6 (E2F transcription factor 6) - Rat Genome Database

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Gene: E2f6 (E2F transcription factor 6) Mus musculus
Analyze
Symbol: E2f6
Name: E2F transcription factor 6
RGD ID: 1552292
MGI Page MGI
Description: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of MLL1 complex and RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human E2F6 (E2F transcription factor 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI462434; E2F-6; E2F-binding site-modulating activity protein; E2F6a; E2F6b; EM; EMA; transcription factor E2F6; transcriptional repressor E2F6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391216,860,932 - 16,876,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1216,860,964 - 16,889,743 (+)EnsemblGRCm39 Ensembl
GRCm381216,810,909 - 16,826,752 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1216,810,963 - 16,839,742 (+)EnsemblGRCm38mm10GRCm38
MGSCv371216,817,771 - 16,833,558 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361216,836,508 - 16,852,232 (+)NCBIMGSCv36mm8
Celera1217,134,343 - 17,150,005 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Giangrande PH, etal., Genes Dev 2004 Dec 1;18(23):2941-51.
2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9403682   PMID:9426200   PMID:9501179   PMID:10349636   PMID:10644441   PMID:10853823   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11171983   PMID:11217851  
PMID:11594747   PMID:12101104   PMID:12383262   PMID:12477932   PMID:14614146   PMID:14681479   PMID:15782199   PMID:15936277   PMID:16141072   PMID:16141073   PMID:16236716   PMID:17001316  
PMID:17210791   PMID:17296600   PMID:18287559   PMID:18366140   PMID:18667754   PMID:19457859   PMID:19741146   PMID:20059953   PMID:20412781   PMID:20439742   PMID:21194568   PMID:21873635  
PMID:22403008   PMID:22770845   PMID:22988430   PMID:23880518   PMID:24952961   PMID:25944088   PMID:26586428   PMID:28925402   PMID:28964969   PMID:29795351   PMID:30981507   PMID:34117224  
PMID:34246625   PMID:34746147   PMID:34857746   PMID:36577384   PMID:37178508  


Genomics

Comparative Map Data
E2f6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391216,860,932 - 16,876,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1216,860,964 - 16,889,743 (+)EnsemblGRCm39 Ensembl
GRCm381216,810,909 - 16,826,752 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1216,810,963 - 16,839,742 (+)EnsemblGRCm38mm10GRCm38
MGSCv371216,817,771 - 16,833,558 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361216,836,508 - 16,852,232 (+)NCBIMGSCv36mm8
Celera1217,134,343 - 17,150,005 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.04NCBI
E2F6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38211,444,375 - 11,466,161 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl211,444,375 - 11,466,177 (-)EnsemblGRCh38hg38GRCh38
GRCh37211,584,501 - 11,606,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36211,501,952 - 11,523,748 (-)NCBINCBI36Build 36hg18NCBI36
Celera211,501,299 - 11,523,094 (-)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef211,434,688 - 11,456,488 (-)NCBIHuRef
CHM1_1211,514,147 - 11,535,955 (-)NCBICHM1_1
T2T-CHM13v2.0211,477,385 - 11,499,173 (-)NCBIT2T-CHM13v2.0
E2f6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,320,993 - 45,337,437 (+)NCBIGRCr8
mRatBN7.2639,592,224 - 39,608,685 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl639,592,228 - 39,608,683 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx639,925,167 - 39,941,452 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0640,239,874 - 40,256,158 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0639,673,145 - 39,689,432 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0642,092,513 - 42,108,692 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl642,092,467 - 42,108,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0651,811,952 - 51,828,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4640,494,286 - 40,534,152 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1640,497,319 - 40,506,745 (+)NCBI
Celera638,900,917 - 38,917,081 (+)NCBICelera
Cytogenetic Map6q16NCBI
E2f6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554876,011,798 - 6,029,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554876,014,476 - 6,029,090 (-)NCBIChiLan1.0ChiLan1.0
E2F6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212115,060,801 - 115,085,200 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A115,066,683 - 115,089,189 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A11,429,887 - 11,452,080 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A11,577,950 - 11,599,732 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A11,577,950 - 11,599,732 (-)Ensemblpanpan1.1panPan2
E2F6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1178,156,535 - 8,178,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl178,157,723 - 8,170,941 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha178,087,626 - 8,109,839 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0178,259,457 - 8,281,868 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl178,260,522 - 8,281,856 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1178,144,343 - 8,166,581 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0178,148,116 - 8,170,364 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0178,167,391 - 8,189,717 (-)NCBIUU_Cfam_GSD_1.0
E2f6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629252,601,479 - 52,619,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365327,356,510 - 7,375,536 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365327,356,525 - 7,375,173 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
E2F6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3125,249,269 - 125,271,037 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13125,248,232 - 125,271,039 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23134,011,073 - 134,023,696 (+)NCBISscrofa10.2Sscrofa10.2susScr3
E2F6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11496,152,374 - 96,172,783 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1496,152,649 - 96,173,708 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604516,080,626 - 16,118,693 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
E2f6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248654,399,077 - 4,412,422 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248654,399,056 - 4,412,131 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in E2f6
510 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:396
Count of miRNA genes:328
Interacting mature miRNAs:354
Transcripts:ENSMUST00000020908
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122418579Mouse
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122418579Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122418579Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122418579Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124662697Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124662697Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127920733Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127920733Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130433078Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132758756Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133430339Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12365000029749999Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
12792982Fbmd4_mfemoral bone mineral density 4, females only (mouse)121004319424365136Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121514733149147331Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121615000147746783Mouse

Markers in Region
AI462434  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,821,314 - 16,821,583UniSTSGRCm38
MGSCv371216,828,120 - 16,828,389UniSTSGRCm37
Celera1217,144,681 - 17,144,958UniSTS
Cytogenetic Map12A1.1UniSTS
Whitehead/MRC_RH12181.31UniSTS
E2f6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A1.1UniSTS
cM Map126.0UniSTS
E2f6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12A1.1UniSTS
cM Map126.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_033270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_027677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB221552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC157352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF032131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF487711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI851823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY739130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ075693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000020908   ⟹   ENSMUSP00000020908
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,860,978 - 16,876,753 (+)Ensembl
GRCm38.p6 Ensembl1216,810,977 - 16,826,752 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220707
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,860,970 - 16,872,628 (+)Ensembl
GRCm38.p6 Ensembl1216,810,969 - 16,822,627 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220794   ⟹   ENSMUSP00000152576
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,860,964 - 16,889,743 (+)Ensembl
GRCm38.p6 Ensembl1216,810,963 - 16,839,742 (+)Ensembl
RefSeq Acc Id: ENSMUST00000221541   ⟹   ENSMUSP00000152314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,861,100 - 16,876,753 (+)Ensembl
GRCm38.p6 Ensembl1216,811,099 - 16,826,752 (+)Ensembl
RefSeq Acc Id: ENSMUST00000221600
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,874,152 - 16,875,510 (+)Ensembl
GRCm38.p6 Ensembl1216,824,151 - 16,825,509 (+)Ensembl
RefSeq Acc Id: ENSMUST00000221934   ⟹   ENSMUSP00000152882
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,861,165 - 16,872,154 (+)Ensembl
GRCm38.p6 Ensembl1216,811,164 - 16,822,153 (+)Ensembl
RefSeq Acc Id: ENSMUST00000222582
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,870,262 - 16,872,687 (+)Ensembl
GRCm38.p6 Ensembl1216,820,261 - 16,822,686 (+)Ensembl
RefSeq Acc Id: NM_033270   ⟹   NP_150373
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,860,966 - 16,876,753 (+)NCBI
GRCm381216,810,965 - 16,826,752 (+)NCBI
MGSCv371216,817,771 - 16,833,558 (+)RGD
Celera1217,134,343 - 17,150,005 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_027677
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,860,966 - 16,876,753 (+)NCBI
GRCm381216,810,965 - 16,826,752 (+)NCBI
MGSCv371216,817,771 - 16,833,558 (+)RGD
Celera1217,134,343 - 17,150,005 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006515147   ⟹   XP_006515210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,860,932 - 16,876,753 (+)NCBI
GRCm381216,810,930 - 16,826,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515148   ⟹   XP_006515211
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,861,227 - 16,876,753 (+)NCBI
GRCm381216,810,930 - 16,826,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515149   ⟹   XP_006515212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,863,939 - 16,876,753 (+)NCBI
GRCm381216,813,932 - 16,826,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157521   ⟹   XP_036013414
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,860,932 - 16,876,753 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_150373   ⟸   NM_033270
- UniProtKB: Q8K456 (UniProtKB/Swiss-Prot),   O54917 (UniProtKB/Swiss-Prot),   Q8VHT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515210   ⟸   XM_006515147
- Peptide Label: isoform X1
- UniProtKB: Q8VHT4 (UniProtKB/TrEMBL),   Q8VHT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515211   ⟸   XM_006515148
- Peptide Label: isoform X1
- UniProtKB: Q8VHT4 (UniProtKB/TrEMBL),   Q8VHT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515212   ⟸   XM_006515149
- Peptide Label: isoform X2
- UniProtKB: Q8VHT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020908   ⟸   ENSMUST00000020908
RefSeq Acc Id: ENSMUSP00000152314   ⟸   ENSMUST00000221541
RefSeq Acc Id: ENSMUSP00000152882   ⟸   ENSMUST00000221934
RefSeq Acc Id: ENSMUSP00000152576   ⟸   ENSMUST00000220794
RefSeq Acc Id: XP_036013414   ⟸   XM_036157521
- Peptide Label: isoform X2
- UniProtKB: Q8VHT5 (UniProtKB/TrEMBL)
Protein Domains
E2F/DP family winged-helix DNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54917-F1-model_v2 AlphaFold O54917 1-272 view protein structure

Promoters
RGD ID:8677952
Promoter ID:EPDNEW_M17007
Type:multiple initiation site
Name:E2f6_1
Description:Mus musculus E2F transcription factor 6 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381216,810,965 - 16,811,025EPDNEW
RGD ID:6822864
Promoter ID:MM_KWN:11216
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000101592,   NM_033270,   NR_027677_E2F6,   UC007NCC.1,   UC007NCD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361216,817,619 - 16,818,119 (+)MPROMDB
RGD ID:6822866
Promoter ID:MM_KWN:11217
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:UC007NCF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361216,828,716 - 16,829,216 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354159 AgrOrtholog
Ensembl Genes ENSMUSG00000057469 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020908 ENTREZGENE
  ENSMUST00000020908.9 UniProtKB/Swiss-Prot
  ENSMUST00000220794.2 UniProtKB/TrEMBL
  ENSMUST00000221541 ENTREZGENE
  ENSMUST00000221541.2 UniProtKB/TrEMBL
  ENSMUST00000221934.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro E2F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E2F-DP_heterodim UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E2F_CC-MB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E2F_WHTH_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50496 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1354159 ENTREZGENE
NCBI Gene 50496 ENTREZGENE
PANTHER PTHR12081 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12081:SF19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam E2F_CC-MB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E2F_TDP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen E2f6 PhenoGen
SMART E2F_TDP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF144074 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1Y7VJU3_MOUSE UniProtKB/TrEMBL
  A0A1Y7VP85_MOUSE UniProtKB/TrEMBL
  E2F6_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8BS58_MOUSE UniProtKB/TrEMBL
  Q8K455_MOUSE UniProtKB/TrEMBL
  Q8K456 ENTREZGENE
  Q8VHT4 ENTREZGENE, UniProtKB/TrEMBL
  Q8VHT5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q8K456 UniProtKB/Swiss-Prot