Or8k28 (olfactory receptor family 8 subfamily K member 28) - Rat Genome Database

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Gene: Or8k28 (olfactory receptor family 8 subfamily K member 28) Mus musculus
Analyze
No known orthologs.
Symbol: Or8k28
Name: olfactory receptor family 8 subfamily K member 28
RGD ID: 1551414
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to act upstream of or within detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR8K3 (olfactory receptor family 8 subfamily K member 3 (gene/pseudogene)).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2Q125-47925557-47924616; MOR188; MOR188-8; MOR256-; MOR256-52P; olfactory receptor 1066; olfactory receptor MOR256-52P; Olfr1066
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Pseudogenes: Or8y1-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39286,285,672 - 86,286,613 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl286,285,672 - 86,286,613 (-)EnsemblGRCm39 Ensembl
GRCm38286,455,328 - 86,456,269 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl286,455,328 - 86,456,269 (-)EnsemblGRCm38mm10GRCm38
MGSCv37286,295,485 - 86,296,426 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36286,256,167 - 86,257,108 (-)NCBIMGSCv36mm8
Celera288,029,322 - 88,030,263 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:15081110   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or8k28
22 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:17
Count of miRNA genes:17
Interacting mature miRNAs:17
Transcripts:ENSMUST00000099885
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1301897Scc2_mcolon tumor susceptibility 2 (mouse)Not determined28572426990410991Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000099885   ⟹   ENSMUSP00000097470
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl286,285,672 - 86,286,613 (-)Ensembl
GRCm38.p6 Ensembl286,455,328 - 86,456,269 (-)Ensembl
RefSeq Acc Id: NM_001011735   ⟹   NP_001011735
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39286,285,672 - 86,286,613 (-)NCBI
GRCm38286,455,328 - 86,456,269 (-)ENTREZGENE
MGSCv37286,295,485 - 86,296,426 (-)RGD
Celera288,029,322 - 88,030,263 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001011735 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP71507 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000097470
  ENSMUSP00000097470.2
Reference Protein Sequences
RefSeq Acc Id: NP_001011735   ⟸   NM_001011735
- UniProtKB: A2AK62 (UniProtKB/TrEMBL),   Q7TR69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000097470   ⟸   ENSMUST00000099885
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AK62-F1-model_v2 AlphaFold A2AK62 1-313 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030900 AgrOrtholog
Ensembl Genes ENSMUSG00000075181 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099885 ENTREZGENE
  ENSMUST00000099885.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:257880 UniProtKB/TrEMBL
MGD MGI:3030900 ENTREZGENE
NCBI Gene 257880 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or8k28 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A2AK62 ENTREZGENE, UniProtKB/TrEMBL
  Q7TR69 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or8k28  olfactory receptor family 8 subfamily K member 28  Olfr1066  olfactory receptor 1066  Symbol and/or name change 5135510 APPROVED