Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LMAN2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LMAN2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of LMAN2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LMAN2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LMAN2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LMAN2 mRNA | CTD | PMID:17942748 | 2-hydroxypropanoic acid | decreases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LMAN2 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] affects the expression of LMAN2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LMAN2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | LMAN2 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of LMAN2 gene | CTD | PMID:31601247 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of LMAN2 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of LMAN2 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | LMAN2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of LMAN2 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of LMAN2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of LMAN2 mRNA | CTD | PMID:34947998 | bisphenol A | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of LMAN2 protein | CTD | PMID:37567409 | bisphenol A | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] affects the expression of LMAN2 mRNA | CTD | PMID:28628672 | Bisphenol B | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of LMAN2 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LMAN2 mRNA | CTD | PMID:28628672 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of LMAN2 mRNA | CTD | PMID:27462272 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of LMAN2 mRNA | CTD | PMID:17585979 | copper(II) sulfate | decreases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of LMAN2 mRNA | CTD | PMID:19549813 | dexamethasone | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] affects the expression of LMAN2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LMAN2 mRNA | CTD | PMID:28628672 | elemental selenium | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of LMAN2 mRNA | CTD | PMID:19244175 | elemental selenium | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Selenium results in increased expression of LMAN2 mRNA | CTD | PMID:19244175 | endosulfan | increases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of LMAN2 mRNA | CTD | PMID:29391264 and PMID:31464424 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of LMAN2 mRNA | CTD | PMID:35436446 | fipronil | increases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of LMAN2 mRNA | CTD | PMID:34044035 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LMAN2 mRNA | CTD | PMID:22206623 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of LMAN2 mRNA | CTD | PMID:25629700 | gentamycin | increases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of LMAN2 mRNA | CTD | PMID:22061828 and PMID:33387578 | indometacin | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] affects the expression of LMAN2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LMAN2 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LMAN2 protein | CTD | PMID:32959892 | manganese atom | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Manganese results in increased expression of LMAN2 mRNA | CTD | PMID:17175027 | manganese(0) | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Manganese results in increased expression of LMAN2 mRNA | CTD | PMID:17175027 | manganese(II) chloride | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | manganese chloride results in increased expression of LMAN2 mRNA | CTD | PMID:17175027 | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of LMAN2 protein | CTD | PMID:26558463 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of LMAN2 mRNA | CTD | PMID:17562736 | rac-lactic acid | decreases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LMAN2 mRNA | CTD | PMID:30851411 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of LMAN2 protein | CTD | PMID:25505154 | resveratrol | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of LMAN2 mRNA | CTD | PMID:23557933 | selenium atom | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of LMAN2 mRNA | CTD | PMID:19244175 | selenium atom | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Selenium results in increased expression of LMAN2 mRNA | CTD | PMID:19244175 | sodium arsenite | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [LMAN2 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of LMAN2 protein | CTD | PMID:27548804 and PMID:28918527 | Soman | increases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | Soman results in increased expression of LMAN2 mRNA | CTD | PMID:19281266 | thioacetamide | decreases expression | ISO | Lman2 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of LMAN2 mRNA | CTD | PMID:34492290 | tunicamycin | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of LMAN2 mRNA | CTD | PMID:22378314 | valproic acid | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LMAN2 mRNA | CTD | PMID:23179753 | valproic acid | increases methylation | ISO | LMAN2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of LMAN2 gene | CTD | PMID:29154799 | vitamin E | multiple interactions | ISO | LMAN2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of LMAN2 mRNA | CTD | PMID:19244175 | vitamin E | increases expression | ISO | LMAN2 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of LMAN2 mRNA | CTD | PMID:19244175 | | 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