Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of WDR47 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of WDR47 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of WDR47 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of WDR47 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of WDR47 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to WDR47 promoter] | CTD | PMID:17942748 and PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of WDR47 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of WDR47 mRNA | CTD | PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of WDR47 mRNA | CTD | PMID:21570461 | 5-azacytidine | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Azacitidine results in decreased expression of WDR47 mRNA | CTD | PMID:19194470 | acrolein | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of WDR47 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of WDR47 mRNA | CTD | PMID:32699268 | acrylamide | increases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of WDR47 mRNA | CTD | PMID:28959563 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of WDR47 mRNA | CTD | PMID:30807115 | aflatoxin B1 | affects expression | ISO | WDR47 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of WDR47 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases methylation | ISO | WDR47 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of WDR47 intron | CTD | PMID:30157460 | aflatoxin B1 | increases methylation | ISO | WDR47 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of WDR47 gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of WDR47 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of WDR47 mRNA | CTD | PMID:32699268 | antirheumatic drug | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of WDR47 mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | WDR47 (Homo sapiens) | 6480464 | Arsenic affects the methylation of WDR47 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | WDR47 (Homo sapiens) | 6480464 | Arsenic affects the methylation of WDR47 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of WDR47 mRNA | CTD | PMID:22316170 | benzo[a]pyrene | affects methylation | ISO | WDR47 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of WDR47 intron and Benzo(a)pyrene affects the methylation of WDR47 promoter | CTD | PMID:27901495 and PMID:30157460 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of WDR47 protein | CTD | PMID:31163220 | bisphenol A | decreases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of WDR47 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of WDR47 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of WDR47 mRNA | CTD | PMID:29275510 | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of WDR47 promoter | CTD | PMID:27312807 | bisphenol A | increases methylation | ISO | Wdr47 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of WDR47 gene | CTD | PMID:28505145 | cadmium dichloride | increases methylation | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased methylation of WDR47 promoter | CTD | PMID:22457795 | cobalt dichloride | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of WDR47 mRNA | CTD | PMID:19376846 | copper(II) sulfate | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of WDR47 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of WDR47 mRNA | CTD | PMID:20106945 and PMID:25562108 | cyclosporin A | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of WDR47 mRNA | CTD | PMID:27989131 | dorsomorphin | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WDR47 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of WDR47 mRNA | CTD | PMID:29803840 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of WDR47 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of WDR47 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of WDR47 mRNA] | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of WDR47 mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | WDR47 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of WDR47 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of WDR47 gene | CTD | PMID:31601247 | furan | increases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | furan results in increased expression of WDR47 mRNA | CTD | PMID:27387713 | ketamine | decreases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of WDR47 mRNA | CTD | PMID:20080153 | Licochalcone B | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of WDR47 mRNA | CTD | PMID:33647349 | methyl methanesulfonate | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of WDR47 mRNA | CTD | PMID:23649840 | methylisothiazolinone | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of WDR47 mRNA | CTD | PMID:31629900 | ozone | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of WDR47 mRNA more ... | CTD | PMID:32699268 | paracetamol | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of WDR47 mRNA | CTD | PMID:21420995 more ... | paracetamol | increases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of WDR47 mRNA | CTD | PMID:33387578 | pirinixic acid | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of WDR47 mRNA | CTD | PMID:19710929 | poly(I:C) | multiple interactions | ISO | Wdr47 (Rattus norvegicus) | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of WDR47 mRNA | CTD | PMID:26923065 | quercetin | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Quercetin results in increased expression of WDR47 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of WDR47 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WDR47 mRNA | CTD | PMID:27188386 | sevoflurane | decreases expression | EXP | | 6480464 | Sevoflurane results in decreased expression of WDR47 protein | CTD | PMID:35249202 | Soman | decreases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of WDR47 mRNA | CTD | PMID:19281266 | thioacetamide | increases expression | ISO | Wdr47 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of WDR47 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichostatin A | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of WDR47 mRNA | CTD | PMID:24935251 | trichostatin A | affects expression | ISO | WDR47 (Homo sapiens) | 6480464 | trichostatin A affects the expression of WDR47 mRNA | CTD | PMID:28542535 | urethane | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Urethane results in increased expression of WDR47 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | WDR47 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of WDR47 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | WDR47 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WDR47 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of WDR47 mRNA | CTD | PMID:23179753 more ... | vorinostat | increases expression | ISO | WDR47 (Homo sapiens) | 6480464 | vorinostat results in increased expression of WDR47 mRNA | CTD | PMID:22083351 | WIN 55212-2 | decreases expression | EXP | | 6480464 | (3R)-((2 more ... | CTD | PMID:12237329 | zebularine | decreases expression | ISO | WDR47 (Homo sapiens) | 6480464 | pyrimidin-2-one beta-ribofuranoside results in decreased expression of WDR47 mRNA | CTD | PMID:19194470 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
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Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
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Biological Process
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48. |
| 2. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:12477932 | PMID:14610273 | PMID:15489334 | PMID:16141072 | PMID:16141073 | PMID:18799693 |
| PMID:21267068 | PMID:21677750 | PMID:22523538 | PMID:28671696 | PMID:29078390 | PMID:30973865 | PMID:32320668 | PMID:32581705 | PMID:34321999 | PMID:34608154 | PMID:36417873 | PMID:38355793 |
Genomics
Comparative Map Data
| Wdr47 (Mus musculus - house mouse) |
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| WDR47 (Homo sapiens - human) |
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| Wdr47 (Rattus norvegicus - Norway rat) |
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| Wdr47 (Chinchilla lanigera - long-tailed chinchilla) |
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| WDR47 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| WDR47 (Canis lupus familiaris - dog) |
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| Wdr47 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| WDR47 (Sus scrofa - pig) |
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| WDR47 (Chlorocebus sabaeus - green monkey) |
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| Wdr47 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Wdr47
1900 total Variants 
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