Sgsm2 (small G protein signaling modulator 2) - Rat Genome Database

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Gene: Sgsm2 (small G protein signaling modulator 2) Mus musculus
Analyze
Symbol: Sgsm2
Name: small G protein signaling modulator 2
RGD ID: 1550615
MGI Page MGI
Description: Enables GTPase activator activity. Predicted to be involved in late endosome to Golgi transport. Located in melanosome. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SGSM2 (small G protein signaling modulator 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D630003G22Rik; mKIAA0397; R74628; RP23-174M12.3; RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; Rutbc; Rutbc1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,740,088 - 74,787,929 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,740,087 - 74,787,886 (-)EnsemblGRCm39 Ensembl
GRCm381174,849,262 - 74,897,211 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,849,261 - 74,897,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv371174,662,766 - 74,710,582 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,665,459 - 74,713,266 (-)NCBIMGSCv36mm8
Celera1182,362,302 - 82,403,240 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
melanosome  (IDA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17509819   PMID:21267068   PMID:21873635   PMID:26620560  
PMID:29459677  


Genomics

Comparative Map Data
Sgsm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,740,088 - 74,787,929 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,740,087 - 74,787,886 (-)EnsemblGRCm39 Ensembl
GRCm381174,849,262 - 74,897,211 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,849,261 - 74,897,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv371174,662,766 - 74,710,582 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,665,459 - 74,713,266 (-)NCBIMGSCv36mm8
Celera1182,362,302 - 82,403,240 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
SGSM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38172,337,501 - 2,381,054 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl172,337,498 - 2,381,058 (+)EnsemblGRCh38hg38GRCh38
GRCh37172,240,795 - 2,284,348 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36172,187,556 - 2,231,098 (+)NCBINCBI36Build 36hg18NCBI36
Celera172,256,908 - 2,300,461 (+)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef172,135,506 - 2,177,896 (+)NCBIHuRef
CHM1_1172,249,759 - 2,291,729 (+)NCBICHM1_1
T2T-CHM13v2.0172,224,838 - 2,269,747 (+)NCBIT2T-CHM13v2.0
Sgsm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,216,556 - 60,258,199 (-)NCBIGRCr8
mRatBN7.21059,718,180 - 59,759,822 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1059,718,183 - 59,759,447 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,364,602 - 64,405,954 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01063,870,189 - 63,911,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,332,564 - 59,373,926 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01061,703,837 - 61,745,110 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,703,839 - 61,745,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,425,573 - 61,467,056 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,165,180 - 62,206,440 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11062,180,270 - 62,220,052 (-)NCBI
Celera1058,748,712 - 58,790,016 (-)NCBICelera
Cytogenetic Map10q24NCBI
Sgsm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955481871,654 - 907,326 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955481871,719 - 907,326 (-)NCBIChiLan1.0ChiLan1.0
SGSM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,918,056 - 9,961,833 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,885,374 - 11,929,243 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0172,328,517 - 2,372,408 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1172,213,183 - 2,256,638 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,213,192 - 2,256,638 (+)Ensemblpanpan1.1panPan2
SGSM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1946,405,890 - 46,464,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl946,415,801 - 46,477,524 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,581,063 - 45,616,639 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0947,262,291 - 47,297,874 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl947,237,076 - 47,297,874 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1946,029,217 - 46,064,789 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,323,745 - 46,359,284 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0946,379,012 - 46,414,591 (+)NCBIUU_Cfam_GSD_1.0
Sgsm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560245,517,957 - 45,558,671 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365388,395,915 - 8,436,655 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365388,395,902 - 8,436,616 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGSM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,416,790 - 48,462,846 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11248,416,774 - 48,462,851 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SGSM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,970,412 - 2,012,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,970,456 - 2,014,384 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605919,949,600 - 19,992,896 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgsm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,999,951 - 5,036,771 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,999,883 - 5,045,208 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sgsm2
1544 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2012
Count of miRNA genes:575
Interacting mature miRNAs:710
Transcripts:ENSMUST00000057631, ENSMUST00000081799, ENSMUST00000123573, ENSMUST00000148421, ENSMUST00000156287
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse

Markers in Region
R74628  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,849,396 - 74,849,546UniSTSGRCm38
MGSCv371174,662,898 - 74,663,048UniSTSGRCm37
Celera1182,362,434 - 82,362,584UniSTS
Cytogenetic Map11B5UniSTS
Whitehead_YAC11 UniSTS
RH125082  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,849,383 - 74,849,546UniSTSGRCm38
MGSCv371174,662,885 - 74,663,048UniSTSGRCm37
Celera1182,362,421 - 82,362,584UniSTS
Cytogenetic Map11B5UniSTS
Sgsm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371174,667,379 - 74,667,966UniSTSGRCm37
Celera1182,366,915 - 82,367,501UniSTS
cM Map11 UniSTS
MARC_16336-16337:1017683698:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,857,619 - 74,858,147UniSTSGRCm38
MGSCv371174,671,121 - 74,671,649UniSTSGRCm37
Celera1182,370,654 - 82,371,182UniSTS
Cytogenetic Map11B5UniSTS
D11Bhm10  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,881,599 - 74,881,740UniSTSGRCm38
MGSCv371174,695,101 - 74,695,242UniSTSGRCm37
Celera1182,394,857 - 82,394,998UniSTS
Cytogenetic Map11B5UniSTS
cM Map1143.85UniSTS
D11Bhm6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,875,766 - 74,875,871UniSTSGRCm38
MGSCv371174,689,268 - 74,689,373UniSTSGRCm37
Celera1182,389,035 - 82,389,140UniSTS
Cytogenetic Map11B5UniSTS
cM Map1143.73UniSTS
D11Bhm8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,851,030 - 74,851,103UniSTSGRCm38
MGSCv371174,664,532 - 74,664,605UniSTSGRCm37
Celera1182,364,068 - 82,364,141UniSTS
Cytogenetic Map11B5UniSTS
cM Map1143.79UniSTS
D11Nds1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,863,834 - 74,863,932UniSTSGRCm38
MGSCv371174,677,336 - 74,677,434UniSTSGRCm37
Celera1182,376,869 - 82,376,967UniSTS
Cytogenetic Map11B5UniSTS
cM Map1143.8UniSTS
Sgsm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,853,877 - 74,854,464UniSTSGRCm38
MGSCv371174,667,379 - 74,667,966UniSTSGRCm37
Celera1182,366,915 - 82,367,501UniSTS
Cytogenetic Map11B5UniSTS
cM Map11 UniSTS
Sgsm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001374688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_197943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_166445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_388560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK078057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL604066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB056852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ062829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000057631   ⟹   ENSMUSP00000050496
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,740,087 - 74,787,886 (-)Ensembl
GRCm38.p6 Ensembl1174,849,261 - 74,897,060 (-)Ensembl
RefSeq Acc Id: ENSMUST00000081799   ⟹   ENSMUSP00000080489
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,740,092 - 74,787,886 (-)Ensembl
GRCm38.p6 Ensembl1174,849,266 - 74,897,060 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,747,393 - 74,751,401 (-)Ensembl
GRCm38.p6 Ensembl1174,856,567 - 74,860,575 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,758,265 - 74,759,214 (-)Ensembl
GRCm38.p6 Ensembl1174,867,439 - 74,868,388 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156287
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,758,255 - 74,759,918 (-)Ensembl
GRCm38.p6 Ensembl1174,867,429 - 74,869,092 (-)Ensembl
RefSeq Acc Id: NM_001374688   ⟹   NP_001361617
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,090 - 74,787,895 (-)NCBI
GRCm381174,849,264 - 74,897,069 (-)NCBI
Sequence:
RefSeq Acc Id: NM_197943   ⟹   NP_922934
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,090 - 74,787,895 (-)NCBI
GRCm381174,849,264 - 74,897,069 (-)NCBI
MGSCv371174,662,766 - 74,710,582 (-)RGD
Celera1182,362,302 - 82,403,240 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_166445
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,090 - 74,787,895 (-)NCBI
GRCm381174,849,264 - 74,897,069 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534583   ⟹   XP_006534646
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,862 (-)NCBI
GRCm381174,849,603 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534584   ⟹   XP_006534647
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,862 (-)NCBI
GRCm381174,849,603 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534585   ⟹   XP_006534648
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,910 (-)NCBI
GRCm381174,849,603 - 74,897,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534587   ⟹   XP_006534650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,759,918 (-)NCBI
GRCm381174,849,603 - 74,869,092 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534589   ⟹   XP_006534652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,758,525 (-)NCBI
GRCm381174,849,603 - 74,867,699 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246447   ⟹   XP_030102307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,909 (-)NCBI
GRCm381174,849,603 - 74,897,083 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246449   ⟹   XP_030102309
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,910 (-)NCBI
GRCm381174,849,603 - 74,897,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246450   ⟹   XP_030102310
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,760,003 (-)NCBI
GRCm381174,849,603 - 74,869,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246451   ⟹   XP_030102311
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,907 (-)NCBI
GRCm381174,849,603 - 74,897,082 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246452   ⟹   XP_030102312
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,787,896 (-)NCBI
GRCm381174,849,603 - 74,897,081 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246454   ⟹   XP_030102314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,759,564 (-)NCBI
GRCm381174,849,603 - 74,868,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157112   ⟹   XP_036013005
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,782,897 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157113   ⟹   XP_036013006
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,429 - 74,759,445 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780082
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,088 - 74,787,929 (-)NCBI
GRCm381174,849,262 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780083
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,088 - 74,787,929 (-)NCBI
GRCm381174,849,262 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780084
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,088 - 74,787,929 (-)NCBI
GRCm381174,849,262 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780085
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,088 - 74,787,929 (-)NCBI
GRCm381174,849,262 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: XR_388560
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,740,088 - 74,787,929 (-)NCBI
GRCm381174,849,262 - 74,897,211 (-)NCBI
Sequence:
RefSeq Acc Id: NP_922934   ⟸   NM_197943
- Peptide Label: isoform 1
- UniProtKB: Q5SWE1 (UniProtKB/Swiss-Prot),   Q5SWE0 (UniProtKB/Swiss-Prot),   Q6PAP8 (UniProtKB/Swiss-Prot),   Q80U12 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534646   ⟸   XM_006534583
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006534647   ⟸   XM_006534584
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006534648   ⟸   XM_006534585
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006534650   ⟸   XM_006534587
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006534652   ⟸   XM_006534589
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_030102309   ⟸   XM_030246449
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030102307   ⟸   XM_030246447
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030102311   ⟸   XM_030246451
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030102312   ⟸   XM_030246452
- Peptide Label: isoform X7
RefSeq Acc Id: XP_030102310   ⟸   XM_030246450
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030102314   ⟸   XM_030246454
- Peptide Label: isoform X9
RefSeq Acc Id: NP_001361617   ⟸   NM_001374688
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000080489   ⟸   ENSMUST00000081799
RefSeq Acc Id: ENSMUSP00000050496   ⟸   ENSMUST00000057631
RefSeq Acc Id: XP_036013005   ⟸   XM_036157112
- Peptide Label: isoform X8
RefSeq Acc Id: XP_036013006   ⟸   XM_036157113
- Peptide Label: isoform X8
Protein Domains
Rab-GAP TBC   RUN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80U12-F1-model_v2 AlphaFold Q80U12 1-1005 view protein structure

Promoters
RGD ID:6822088
Promoter ID:MM_KWN:8462
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Spleen
Transcripts:OTTMUST00000013941
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361174,673,594 - 74,674,094 (-)MPROMDB
RGD ID:6822089
Promoter ID:MM_KWN:8463
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000013943
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361174,681,951 - 74,682,451 (-)MPROMDB
RGD ID:6822090
Promoter ID:MM_KWN:8465
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000081799,   OTTMUST00000013939
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361174,710,286 - 74,711,567 (-)MPROMDB
RGD ID:8675510
Promoter ID:EPDNEW_M15786
Type:multiple initiation site
Name:Sgsm2_1
Description:Mus musculus small G protein signaling modulator 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381174,897,069 - 74,897,129EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2144695 AgrOrtholog
Ensembl Genes ENSMUSG00000038351 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000057631 ENTREZGENE
  ENSMUST00000057631.12 UniProtKB/Swiss-Prot
  ENSMUST00000081799 ENTREZGENE
  ENSMUST00000081799.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.900 UniProtKB/Swiss-Prot
  2.30.29.230 UniProtKB/Swiss-Prot
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/Swiss-Prot
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/Swiss-Prot
InterPro Rab-GTPase-TBC_dom UniProtKB/Swiss-Prot
  Rab-GTPase_TBC_sf UniProtKB/Swiss-Prot
  Run_dom UniProtKB/Swiss-Prot
  Run_dom_sf UniProtKB/Swiss-Prot
  RUN_SGSM2 UniProtKB/Swiss-Prot
  SGSM1/2 UniProtKB/Swiss-Prot
  SGSM1/2_RBD UniProtKB/Swiss-Prot
KEGG Report mmu:97761 UniProtKB/Swiss-Prot
MGD MGI:2144695 ENTREZGENE
NCBI Gene 97761 ENTREZGENE
PANTHER SMALL G PROTEIN SIGNALING MODULATOR 2 UniProtKB/Swiss-Prot
  TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UniProtKB/Swiss-Prot
Pfam PH_RBD UniProtKB/Swiss-Prot
  RabGAP-TBC UniProtKB/Swiss-Prot
  RUN UniProtKB/Swiss-Prot
PhenoGen Sgsm2 PhenoGen
PROSITE RUN UniProtKB/Swiss-Prot
  TBC_RABGAP UniProtKB/Swiss-Prot
SMART RUN UniProtKB/Swiss-Prot
  TBC UniProtKB/Swiss-Prot
Superfamily-SCOP SSF140741 UniProtKB/Swiss-Prot
  SSF47923 UniProtKB/Swiss-Prot
UniProt Q5SWE0 ENTREZGENE
  Q5SWE1 ENTREZGENE
  Q6PAP8 ENTREZGENE
  Q80U12 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q5SWE0 UniProtKB/Swiss-Prot
  Q5SWE1 UniProtKB/Swiss-Prot
  Q6PAP8 UniProtKB/Swiss-Prot