PRELP (proline and arginine rich end leucine rich repeat protein) - Rat Genome Database

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Gene: PRELP (proline and arginine rich end leucine rich repeat protein) Sus scrofa
Analyze
Symbol: PRELP
Name: proline and arginine rich end leucine rich repeat protein
RGD ID: 14294432
Description: ENCODES a protein that exhibits heparin binding (ortholog); INVOLVED IN cellular senescence (ortholog); ASSOCIATED WITH familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); Hypokalemic Periodic Paralysis, Type 1 (ortholog); FOUND IN extracellular exosome (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prolargin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl964,190,982 - 64,207,001 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1964,190,978 - 64,207,008 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2970,484,576 - 70,500,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRELP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl964,190,982 - 64,207,001 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1964,190,978 - 64,207,008 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2970,484,576 - 70,500,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRELP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381203,475,806 - 203,491,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1203,475,806 - 203,491,352 (+)EnsemblGRCh38hg38GRCh38
GRCh371203,444,934 - 203,460,480 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,711,506 - 201,727,103 (+)NCBINCBI36Build 36hg18NCBI36
Build 341200,176,539 - 200,192,134NCBI
Celera1176,574,517 - 176,590,114 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1174,609,796 - 174,625,529 (+)NCBIHuRef
CHM1_11204,867,696 - 204,883,317 (+)NCBICHM1_1
T2T-CHM13v2.01202,738,636 - 202,754,205 (+)NCBIT2T-CHM13v2.0
Prelp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,838,042 - 133,857,820 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,838,042 - 133,849,152 (-)EnsemblGRCm39 Ensembl
GRCm381133,910,304 - 133,930,102 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,910,304 - 133,921,414 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,806,881 - 135,817,978 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361135,726,689 - 135,737,788 (-)NCBIMGSCv36mm8
Celera1136,525,698 - 136,536,797 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.02NCBI
Prelp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81347,920,480 - 47,943,547 (-)NCBIGRCr8
mRatBN7.21345,368,407 - 45,391,480 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1345,370,533 - 45,380,270 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1347,979,705 - 47,988,845 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01349,267,749 - 49,276,889 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01346,532,376 - 46,541,463 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01350,749,526 - 50,773,934 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1350,749,514 - 50,761,355 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01355,802,758 - 55,827,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41346,863,392 - 46,874,172 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11346,877,436 - 46,888,215 (-)NCBI
Celera1345,699,857 - 45,709,383 (-)NCBICelera
Cytogenetic Map13q13NCBI
Prelp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,429,690 - 39,443,299 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,429,845 - 39,442,577 (+)NCBIChiLan1.0ChiLan1.0
PRELP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2145,889,452 - 45,901,902 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1145,854,053 - 45,868,942 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01179,077,892 - 179,092,796 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11183,372,022 - 183,386,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1183,372,028 - 183,386,619 (+)Ensemblpanpan1.1panPan2
PRELP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.138198,681 - 212,320 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl38198,583 - 209,937 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha38294,916 - 308,561 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.038195,264 - 208,935 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl38195,237 - 208,922 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.138187,599 - 201,248 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.038581,675 - 595,334 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.038795,591 - 809,246 (+)NCBIUU_Cfam_GSD_1.0
Prelp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934471,920,731 - 71,934,667 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,155,292 - 1,169,467 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,155,348 - 1,169,276 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRELP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12525,854,443 - 25,867,179 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2525,851,674 - 25,867,177 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605526,627,734 - 26,642,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prelp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248077,403,305 - 7,413,414 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248077,400,999 - 7,413,455 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PRELP
507 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 1 1 3 1 1 1
Low 8 3 2 2 2 21 1 2 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000040438   ⟹   ENSSSCP00000051002
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,190,982 - 64,207,001 (+)Ensembl
RefSeq Acc Id: XM_003130106   ⟹   XP_003130154
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,190,982 - 64,207,008 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005656649   ⟹   XP_005656706
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,190,978 - 64,206,994 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005656706   ⟸   XM_005656649
- UniProtKB: F1S6B4 (UniProtKB/TrEMBL),   A0A4X1V6K8 (UniProtKB/TrEMBL),   A0A8D0N186 (UniProtKB/TrEMBL),   A0A8D0N4Z7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003130154   ⟸   XM_003130106
- UniProtKB: F1S6B4 (UniProtKB/TrEMBL),   A0A4X1V6K8 (UniProtKB/TrEMBL),   A0A8D0N186 (UniProtKB/TrEMBL),   A0A8D0N4Z7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000051002   ⟸   ENSSSCT00000040438
Protein Domains
LRRNT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005018467 UniProtKB/TrEMBL
  ENSSSCG00015023037 UniProtKB/TrEMBL
  ENSSSCG00025009975 UniProtKB/TrEMBL
  ENSSSCG00040024803 UniProtKB/TrEMBL
  ENSSSCG00045033716 UniProtKB/TrEMBL
  ENSSSCG00050060186 UniProtKB/TrEMBL
  ENSSSCG00055023418 UniProtKB/TrEMBL
  ENSSSCG00060059767 UniProtKB/TrEMBL
  ENSSSCG00065064186 UniProtKB/TrEMBL
  ENSSSCG00070021775 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040438 ENTREZGENE
  ENSSSCT00000040438.3 UniProtKB/TrEMBL
  ENSSSCT00005029088.1 UniProtKB/TrEMBL
  ENSSSCT00015030533.1 UniProtKB/TrEMBL
  ENSSSCT00015030623.1 UniProtKB/TrEMBL
  ENSSSCT00025013142.1 UniProtKB/TrEMBL
  ENSSSCT00040033129.1 UniProtKB/TrEMBL
  ENSSSCT00045057687.1 UniProtKB/TrEMBL
  ENSSSCT00050081992.1 UniProtKB/TrEMBL
  ENSSSCT00055046090.1 UniProtKB/TrEMBL
  ENSSSCT00060081524.1 UniProtKB/TrEMBL
  ENSSSCT00065088109.1 UniProtKB/TrEMBL
  ENSSSCT00070043267.1 UniProtKB/TrEMBL
  ENSSSCT00070043271.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
KEGG Report ssc:100511032 UniProtKB/TrEMBL
NCBI Gene PRELP ENTREZGENE
PANTHER AGAP008170-PA UniProtKB/TrEMBL
  PTHR45712:SF8 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A4X1V6K8 ENTREZGENE
  A0A8D0N186 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0N4Z7 ENTREZGENE, UniProtKB/TrEMBL
  F1S6B4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1V6K8 UniProtKB/TrEMBL
VGNC ID VGNC:91789 ENTREZGENE