PRELP (proline and arginine rich end leucine rich repeat protein) - Rat Genome Database

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Gene: PRELP (proline and arginine rich end leucine rich repeat protein) Pan paniscus
Analyze
Symbol: PRELP
Name: proline and arginine rich end leucine rich repeat protein
RGD ID: 11680254
Description: ENCODES a protein that exhibits heparin binding (ortholog); INVOLVED IN cellular senescence (ortholog); ASSOCIATED WITH familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); Hypokalemic Periodic Paralysis, Type 1 (ortholog); FOUND IN extracellular exosome (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prolargin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2145,889,452 - 45,901,902 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1145,854,053 - 45,868,942 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01179,077,892 - 179,092,796 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11183,372,022 - 183,386,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1183,372,028 - 183,386,619 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
heparin binding  (IEA,ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRELP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2145,889,452 - 45,901,902 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1145,854,053 - 45,868,942 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01179,077,892 - 179,092,796 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11183,372,022 - 183,386,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1183,372,028 - 183,386,619 (+)Ensemblpanpan1.1panPan2
PRELP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381203,475,806 - 203,491,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1203,475,806 - 203,491,352 (+)EnsemblGRCh38hg38GRCh38
GRCh371203,444,934 - 203,460,480 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,711,506 - 201,727,103 (+)NCBINCBI36Build 36hg18NCBI36
Build 341200,176,539 - 200,192,134NCBI
Celera1176,574,517 - 176,590,114 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1174,609,796 - 174,625,529 (+)NCBIHuRef
CHM1_11204,867,696 - 204,883,317 (+)NCBICHM1_1
T2T-CHM13v2.01202,738,636 - 202,754,205 (+)NCBIT2T-CHM13v2.0
Prelp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,838,042 - 133,857,820 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,838,042 - 133,849,152 (-)EnsemblGRCm39 Ensembl
GRCm381133,910,304 - 133,930,102 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,910,304 - 133,921,414 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,806,881 - 135,817,978 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361135,726,689 - 135,737,788 (-)NCBIMGSCv36mm8
Celera1136,525,698 - 136,536,797 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.02NCBI
Prelp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81347,920,480 - 47,943,547 (-)NCBIGRCr8
mRatBN7.21345,368,407 - 45,391,480 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1345,370,533 - 45,380,270 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1347,979,705 - 47,988,845 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01349,267,749 - 49,276,889 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01346,532,376 - 46,541,463 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01350,749,526 - 50,773,934 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1350,749,514 - 50,761,355 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01355,802,758 - 55,827,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41346,863,392 - 46,874,172 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11346,877,436 - 46,888,215 (-)NCBI
Celera1345,699,857 - 45,709,383 (-)NCBICelera
Cytogenetic Map13q13NCBI
Prelp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,429,690 - 39,443,299 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,429,845 - 39,442,577 (+)NCBIChiLan1.0ChiLan1.0
PRELP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.138198,681 - 212,320 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl38198,583 - 209,937 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha38294,916 - 308,561 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.038195,264 - 208,935 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl38195,237 - 208,922 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.138187,599 - 201,248 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.038581,675 - 595,334 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.038795,591 - 809,246 (+)NCBIUU_Cfam_GSD_1.0
Prelp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934471,920,731 - 71,934,667 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,155,292 - 1,169,467 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,155,348 - 1,169,276 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRELP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl964,190,982 - 64,207,001 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1964,190,978 - 64,207,008 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2970,484,576 - 70,500,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRELP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12525,854,443 - 25,867,179 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2525,851,674 - 25,867,177 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605526,627,734 - 26,642,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prelp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248077,403,305 - 7,413,414 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248077,400,999 - 7,413,455 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000039467   ⟹   ENSPPAP00000016769
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1183,372,028 - 183,386,619 (+)Ensembl
RefSeq Acc Id: XM_003822987   ⟹   XP_003823035
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2145,889,452 - 45,901,902 (-)NCBI
NHGRI_mPanPan1145,854,053 - 45,868,942 (-)NCBI
Mhudiblu_PPA_v01179,077,892 - 179,092,796 (+)NCBI
PanPan1.11183,372,028 - 183,386,626 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976602   ⟹   XP_008974850
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2145,889,452 - 45,901,884 (-)NCBI
NHGRI_mPanPan1145,854,053 - 45,868,931 (-)NCBI
Mhudiblu_PPA_v01179,077,896 - 179,092,796 (+)NCBI
PanPan1.11183,372,022 - 183,386,626 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063597889   ⟹   XP_063453959
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2145,889,452 - 45,897,234 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003823035 (Get FASTA)   NCBI Sequence Viewer  
  XP_008974850 (Get FASTA)   NCBI Sequence Viewer  
  XP_063453959 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000016769
  ENSPPAP00000016769.1
Reference Protein Sequences
RefSeq Acc Id: XP_008974850   ⟸   XM_008976602
- Peptide Label: isoform X2
- UniProtKB: A0A2R9APH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003823035   ⟸   XM_003822987
- Peptide Label: isoform X2
- UniProtKB: A0A2R9APH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000016769   ⟸   ENSPPAT00000039467
RefSeq Acc Id: XP_063453959   ⟸   XM_063597889
- Peptide Label: isoform X1
Protein Domains
LRRNT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031486 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039467.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
KEGG Report pps:100990076 UniProtKB/TrEMBL
NCBI Gene PRELP ENTREZGENE
PANTHER AGAP008170-PA UniProtKB/TrEMBL
  PTHR45712:SF8 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A2R9APH9 ENTREZGENE, UniProtKB/TrEMBL