CIB4 (calcium and integrin binding family member 4)

Gene: CIB4 (calcium and integrin binding family member 4) Sus scrofa

Analyze

Symbol:

CIB4

Name:

calcium and integrin binding family member 4

RGD ID:

14270227

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); magnesium ion binding (inferred); metal ion binding (inferred); ASSOCIATED WITH Tatton-Brown-Rahman syndrome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

calcium and integrin-binding family member 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	112,406,908 - 112,457,138 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	112,415,709 - 112,457,253 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	119,405,976 - 119,456,544 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Tatton-Brown-Rahman syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

calcium ion binding (IEA)

magnesium ion binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

CIB4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	112,406,908 - 112,457,138 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	112,415,709 - 112,457,253 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	119,405,976 - 119,456,544 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CIB4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	26,581,205 - 26,641,366 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	26,581,205 - 26,641,366 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	26,804,073 - 26,864,234 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	26,657,577 - 26,717,715 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	26,647,704 - 26,707,827 (-)	NCBI		Celera
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	26,543,509 - 26,603,418 (-)	NCBI		HuRef
CHM1_1	2	26,734,122 - 26,794,199 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	26,620,353 - 26,681,744 (-)	NCBI		T2T-CHM13v2.0

Cib4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	30,642,927 - 30,703,191 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	30,642,927 - 30,703,180 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	30,485,583 - 30,545,845 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	30,485,583 - 30,545,836 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	30,787,957 - 30,848,209 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	30,762,164 - 30,822,417 (-)	NCBI		MGSCv36	mm8
Celera	5	27,963,768 - 28,024,353 (-)	NCBI		Celera
Cytogenetic Map	5	B1	NCBI
cM Map	5	16.59	NCBI

Cib4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	31,560,105 - 31,623,403 (+)	NCBI		GRCr8
mRatBN7.2	6	25,842,605 - 25,903,509 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	25,842,622 - 25,917,206 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	6	27,241,804 - 27,303,617 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	27,241,919 - 27,303,615 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	37,058,400 - 37,115,989 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	25,825,158 - 25,887,430 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	25,324,446 - 25,382,084 (+)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

Cib4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	8,604,799 - 8,669,916 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	8,604,866 - 8,669,890 (-)	NCBI	ChiLan1.0	ChiLan1.0

CIB4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	99,876,073 - 99,936,088 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	99,880,053 - 99,940,041 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	26,578,051 - 26,670,672 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	26,669,870 - 26,729,792 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

CIB4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	20,635,050 - 20,685,775 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	20,635,214 - 20,685,675 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	20,529,315 - 20,579,886 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	20,956,432 - 21,007,233 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	20,956,420 - 21,007,151 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	20,643,373 - 20,694,146 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	20,654,507 - 20,705,263 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	20,700,854 - 20,751,456 (-)	NCBI		UU_Cfam_GSD_1.0

Cib4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	64,945,208 - 64,996,761 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	5,842,964 - 5,894,306 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	5,805,911 - 5,894,306 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

Cib4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	8,718,687 - 8,771,025 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	8,704,726 - 8,813,441 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CIB4
2102 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	nervous system	reproductive system
High
Medium
Low	2	3	1
Below cutoff	1	14

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021087727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021087728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000009370 ⟹ ENSSSCP00000009130

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	112,406,908 - 112,457,138 (+)	Ensembl

RefSeq Acc Id:

XM_021087727 ⟹ XP_020943386

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	112,415,709 - 112,457,253 (+)	NCBI

Sequence:

show sequence

AATGAGGACAGAAGGCCCTTCCAGGGCACTTGCAAGCTGTGTTCAGGCTACAGGGCACCTTCGT
GTACCTTTCCTTGGGCCTGGCTTATCCTTAAATCCCCGGGACACACTGGAGCCTGAGGGATGTT
TCTGCAAGGGCAGAATGATTTATAACTGCCTTCTCTATGTCAATCAATCCTGAGTCCCCTTCCT
CCCAAGACAGCTTGCAGGCGAAGGGGGCAGCCTGCTGGTCCCCACTCCCAGCCCACCATGCCTC
TCTTCTCAGCATCCATGACTCCTTCCTGAAGCTCTGCCCCCCTGGAAAATACTACAAGGAGGCC
ACGCTGACCATGGACCAGGTCAGCTCCCTGCCGGCCCTGAGGGTCAACCCTTTCAGAGACCGAA
TCTGCAGAGTGTTCTCCCACAACGACGTGTTCTGCTTTGAGGATGTGCTGGGCATGGCATCTGT
GTTCAGCGAGCAGGCCTGCCCCAGCCTGAAGATCGAGTATGCCTTCCGCATCTACGATTTTAAC
GAGAATGGCTTCATCGACGAGGAGGACCTGCAAAGGATCATCCTTCGGCTGCTCAACAGCAACG
ACATGTCCGAGGACCTGCTCACTGACCTCACCAGCCGCGTGTGTGCCCGGGGCTGCGGGGTGCT
GGATGAGTCAGACCTGGACAATGACAACATGCTGTCCTTCTCCGAGTTTGAGCACGCAATGGCC
AAATCTCCAGACTTCATGAACTCCTTTCGGATTCACTTCTGGGGATACTGATGAATAGCTGATC
TGGACCCCCTGGAACTTGGAATTCCACCCCCTGCAGGTGCTGGGAGAAATCTGATTAGAAGAAT
GACTGTCCCCATCCCTCCCTCTCTTCTAGAAAATTGTTTATTCAATAAAGCCAAAGAAAAGCCT
GTCCCTGGCTCCCTCACTTCATCATTTTTTGAATGCAAGTCATAGAGAAGTACTTCCCGCCCCC
TTTTTAAGGGCGGCGCATGTGGCTTATGGAAGTTCCTGGGCTAGGGATT

hide sequence

RefSeq Acc Id:

XM_021087728 ⟹ XP_020943387

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	112,415,709 - 112,457,251 (+)	NCBI

Sequence:

show sequence

AATGAGGACAGAAGGCCCTTCCAGGGCACTTGCAAGCTGTGTTCAGGCTACAGGGCACCTTCGT
GTACCTTTCCTTGGGCCTGGCTTATCCTTAAATCCCCGGGACACACTGGAGCCTGAGGGATGTT
TCTGCAAGGGCAGAATGATTTATAACTGCCTTCTCTATGTCAATCAATCCTGAGTCCCCTTCCT
CCCAAGACAGCTTGCAGGCGAAGGGGGCAGCCTGCTGGTCCCCACTCCCAGCCCACCATGCCTC
TCTTCTCAGCATCCATGACTCCTTCCTGAAGCTCTGCCCCCCTGGAAAATACTACAAGGAGGCC
ACGCTGACCATGGACCAGGTCAGCTCCCTGCCGGCCCTGAGGGTCAACCCTTTCAGAGACCGAA
TCTGCAGAGTGTTCTCCCACAACGACGTGTTCTGCTTTGAGGATGTGCTGGGCATGGCATCTGT
GTTCAGCGAGCAGGCCTGCCCCAGCCTGAAGATCGAGTATGCCTTCCGCATCTACGATTTTAAC
GAGAATGGCTTCATCGACGAGGAGGACCTGCAAAGGATCATCCTTCGGCTGCTCAACAGCAACG
ACATGTCCGAGGACCTGCTCACTGACCTCACCAGCCGCGTGCTGGATGAGTCAGACCTGGACAA
TGACAACATGCTGTCCTTCTCCGAGTTTGAGCACGCAATGGCCAAATCTCCAGACTTCATGAAC
TCCTTTCGGATTCACTTCTGGGGATACTGATGAATAGCTGATCTGGACCCCCTGGAACTTGGAA
TTCCACCCCCTGCAGGTGCTGGGAGAAATCTGATTAGAAGAATGACTGTCCCCATCCCTCCCTC
TCTTCTAGAAAATTGTTTATTCAATAAAGCCAAAGAAAAGCCTGTCCCTGGCTCCCTCACTTCA
TCATTTTTTGAATGCAAGTCATAGAGAAGTACTTCCCGCCCCCTTTTTAAGGGCGGCGCATGTG
GCTTATGGAAGTTCCTGGGCTAGGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020943386	(Get FASTA)	NCBI Sequence Viewer
	XP_020943387	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000009130.2
	ENSSSCP00005044003.1
	ENSSSCP00005044039.1
	ENSSSCP00015013634.1
	ENSSSCP00025037237.1
	ENSSSCP00030031811.1
	ENSSSCP00035040655.1
	ENSSSCP00035040664.1
	ENSSSCP00040046658.1
	ENSSSCP00045005100.1
	ENSSSCP00050030025.1
	ENSSSCP00055011952.1
	ENSSSCP00060027751.1
	ENSSSCP00065012906.1
	ENSSSCP00070018876.1
	ENSSSCP00070018883.1
	ENSSSCP00070018887.1
	ENSSSCP00070018892.1

RefSeq Acc Id:	XP_020943386 ⟸ XM_021087727
- Peptide Label:	isoform X1
- UniProtKB:	A0A8D1TXT6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSINPESPSSQDSLQAKGAACWSPLPAHHASLLSIHDSFLKLCPPGKYYKEATLTMDQVSSLPA LRVNPFRDRICRVFSHNDVFCFEDVLGMASVFSEQACPSLKIEYAFRIYDFNENGFIDEEDLQR IILRLLNSNDMSEDLLTDLTSRVCARGCGVLDESDLDNDNMLSFSEFEHAMAKSPDFMNSFRIH FWGY hide sequence

RefSeq Acc Id:	XP_020943387 ⟸ XM_021087728
- Peptide Label:	isoform X2
- UniProtKB:	A0A4X1TRH9 (UniProtKB/TrEMBL), A0A8D1TXT6 (UniProtKB/TrEMBL), A0A8D0TQB2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSINPESPSSQDSLQAKGAACWSPLPAHHASLLSIHDSFLKLCPPGKYYKEATLTMDQVSSLPA LRVNPFRDRICRVFSHNDVFCFEDVLGMASVFSEQACPSLKIEYAFRIYDFNENGFIDEEDLQR IILRLLNSNDMSEDLLTDLTSRVLDESDLDNDNMLSFSEFEHAMAKSPDFMNSFRIHFWGY hide sequence

RefSeq Acc Id:

ENSSSCP00000009130 ⟸ ENSSSCT00000009370

Protein Domains

EF-hand

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000008564	Ensembl, UniProtKB/TrEMBL
	ENSSSCG00005043932	UniProtKB/TrEMBL
	ENSSSCG00015025967	UniProtKB/TrEMBL
	ENSSSCG00025062576	UniProtKB/TrEMBL
	ENSSSCG00030050029	UniProtKB/TrEMBL
	ENSSSCG00035071406	UniProtKB/TrEMBL
	ENSSSCG00040074570	UniProtKB/TrEMBL
	ENSSSCG00045004516	UniProtKB/TrEMBL
	ENSSSCG00050051294	UniProtKB/TrEMBL
	ENSSSCG00055007779	UniProtKB/TrEMBL
	ENSSSCG00060047759	UniProtKB/TrEMBL
	ENSSSCG00065023705	UniProtKB/TrEMBL
	ENSSSCG00070011702	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000009370.5	UniProtKB/TrEMBL
	ENSSSCT00005070599.1	UniProtKB/TrEMBL
	ENSSSCT00005070643.1	UniProtKB/TrEMBL
	ENSSSCT00015034427.1	UniProtKB/TrEMBL
	ENSSSCT00025085659.1	UniProtKB/TrEMBL
	ENSSSCT00030069728.1	UniProtKB/TrEMBL
	ENSSSCT00035096530.1	UniProtKB/TrEMBL
	ENSSSCT00035096542.1	UniProtKB/TrEMBL
	ENSSSCT00040103105.1	UniProtKB/TrEMBL
	ENSSSCT00045007482.1	UniProtKB/TrEMBL
	ENSSSCT00050069837.1	UniProtKB/TrEMBL
	ENSSSCT00055015206.1	UniProtKB/TrEMBL
	ENSSSCT00060064813.1	UniProtKB/TrEMBL
	ENSSSCT00065031546.1	UniProtKB/TrEMBL
	ENSSSCT00070022826.1	UniProtKB/TrEMBL
	ENSSSCT00070022835.1	UniProtKB/TrEMBL
	ENSSSCT00070022838.1	UniProtKB/TrEMBL
	ENSSSCT00070022845.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
NCBI Gene	CIB4	ENTREZGENE
PANTHER	CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2	UniProtKB/TrEMBL
	CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 4	UniProtKB/TrEMBL
Pfam	EF-hand_7	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A4X1TRH9	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1TRI4_PIG	UniProtKB/TrEMBL
	A0A4X1TU30_PIG	UniProtKB/TrEMBL
	A0A4X1TUA3_PIG	UniProtKB/TrEMBL
	A0A8D0N4J9_PIG	UniProtKB/TrEMBL
	A0A8D0TQB2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1TXT6	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1SDN9	UniProtKB/TrEMBL
VGNC ID	VGNC:86697	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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