POLR3A (RNA polymerase III subunit A) - Rat Genome Database

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Gene: POLR3A (RNA polymerase III subunit A) Sus scrofa
Analyze
Symbol: POLR3A
Name: RNA polymerase III subunit A
RGD ID: 14233062
Description: ENCODES a protein that exhibits 5'-3' RNA polymerase activity (inferred); chromatin binding (inferred); DNA binding (inferred); INVOLVED IN DNA-templated transcription (inferred); innate immune response (inferred); positive regulation of interferon-beta production (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH Diamond-Blackfan anemia (ortholog); Diamond-Blackfan anemia 3 (ortholog); Dysmyelinating Leukodystrophy with Oligodontia (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); nuclear lumen (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA-directed RNA polymerase III subunit RPC1; polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1480,413,099 - 80,471,697 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11480,410,143 - 80,471,740 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21486,944,625 - 87,003,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
POLR3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1480,413,099 - 80,471,697 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11480,410,143 - 80,471,740 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21486,944,625 - 87,003,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLR3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381077,975,149 - 78,029,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1077,953,148 - 78,029,522 (-)EnsemblGRCh38hg38GRCh38
GRCh371079,734,907 - 79,789,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361079,405,900 - 79,459,265 (-)NCBINCBI36Build 36hg18NCBI36
Build 341079,405,911 - 79,459,265NCBI
Celera1073,021,499 - 73,075,893 (-)NCBICelera
Cytogenetic Map10q22.3NCBI
HuRef1073,729,855 - 73,784,226 (-)NCBIHuRef
CHM1_11080,017,697 - 80,072,040 (-)NCBICHM1_1
T2T-CHM13v2.01078,844,187 - 78,898,555 (-)NCBIT2T-CHM13v2.0
Polr3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391424,498,762 - 24,537,126 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1424,498,764 - 24,537,126 (-)EnsemblGRCm39 Ensembl
GRCm381424,448,694 - 24,487,070 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1424,448,696 - 24,487,058 (-)EnsemblGRCm38mm10GRCm38
MGSCv371425,267,916 - 25,306,268 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361423,281,159 - 23,319,511 (-)NCBIMGSCv36mm8
Celera1420,823,678 - 20,861,770 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1414.4NCBI
Polr3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81656,066 - 95,060 (-)NCBIGRCr8
mRatBN7.21649,178 - 88,178 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1649,521 - 88,172 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.016717,821 - 756,002 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl16716,683 - 755,990 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.016712,735 - 750,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4164,090 - 42,301 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1164,027 - 40,227 (-)NCBI
Celera1636,720 - 74,901 (-)NCBICelera
Cytogenetic Map16p16NCBI
Polr3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543714,446,024 - 14,483,336 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543714,446,059 - 14,483,336 (+)NCBIChiLan1.0ChiLan1.0
POLR3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2890,123,792 - 90,178,184 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11090,129,578 - 90,183,507 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01074,496,121 - 74,550,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11077,157,976 - 77,213,019 (-)NCBIpanpan1.1PanPan1.1panPan2
POLR3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1427,834,197 - 27,883,065 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl427,835,612 - 27,883,436 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha427,959,412 - 28,008,179 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0428,135,868 - 28,184,686 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl428,135,868 - 28,184,984 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1428,010,348 - 28,059,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0428,209,234 - 28,258,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0428,562,062 - 28,611,378 (-)NCBIUU_Cfam_GSD_1.0
Polr3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721353,078,129 - 53,121,757 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365211,570,857 - 1,614,409 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365211,570,863 - 1,613,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1953,411,869 - 53,462,773 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl953,411,889 - 53,464,668 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604813,832,883 - 13,883,800 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polr3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475411,173,601 - 11,215,258 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475411,166,126 - 11,215,205 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in POLR3A
1736 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 10 4 3 4 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011305   ⟹   ENSSSCP00000011013
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1480,413,099 - 80,471,697 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000046109   ⟹   ENSSSCP00000033300
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1480,413,099 - 80,471,697 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000047864   ⟹   ENSSSCP00000034538
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1480,410,147 - 80,471,679 (-)Ensembl
RefSeq Acc Id: XM_001929360   ⟹   XP_001929395
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11480,410,143 - 80,471,740 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013983365   ⟹   XP_013838819
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11480,413,111 - 80,471,735 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001929395   ⟸   XM_001929360
- Peptide Label: isoform X2
- UniProtKB: A0A4X1SJU1 (UniProtKB/TrEMBL),   F1S2E6 (UniProtKB/TrEMBL),   A0A8D1IMQ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013838819   ⟸   XM_013983365
- Peptide Label: isoform X1
- UniProtKB: A0A8D1SC59 (UniProtKB/TrEMBL),   A0A8D1IHA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000011013   ⟸   ENSSSCT00000011305
RefSeq Acc Id: ENSSSCP00000033300   ⟸   ENSSSCT00000046109
RefSeq Acc Id: ENSSSCP00000034538   ⟸   ENSSSCT00000047864
Protein Domains
RNA polymerase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010327 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025066282 UniProtKB/TrEMBL
  ENSSSCG00030020005 UniProtKB/TrEMBL
  ENSSSCG00035008135 UniProtKB/TrEMBL
  ENSSSCG00040031274 UniProtKB/TrEMBL
  ENSSSCG00045029586 UniProtKB/TrEMBL
  ENSSSCG00050054423 UniProtKB/TrEMBL
  ENSSSCG00055029491 UniProtKB/TrEMBL
  ENSSSCG00060066020 UniProtKB/TrEMBL
  ENSSSCG00065044084 UniProtKB/TrEMBL
  ENSSSCG00070001708 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011305 ENTREZGENE
  ENSSSCT00000011305.5 UniProtKB/TrEMBL
  ENSSSCT00000046109 ENTREZGENE
  ENSSSCT00000046109.3 UniProtKB/TrEMBL
  ENSSSCT00025091029.1 UniProtKB/TrEMBL
  ENSSSCT00030027635.1 UniProtKB/TrEMBL
  ENSSSCT00030027688.1 UniProtKB/TrEMBL
  ENSSSCT00030027714.1 UniProtKB/TrEMBL
  ENSSSCT00035010130.1 UniProtKB/TrEMBL
  ENSSSCT00040042074.1 UniProtKB/TrEMBL
  ENSSSCT00040042279.1 UniProtKB/TrEMBL
  ENSSSCT00040042444.1 UniProtKB/TrEMBL
  ENSSSCT00045050517.1 UniProtKB/TrEMBL
  ENSSSCT00045050822.1 UniProtKB/TrEMBL
  ENSSSCT00050074209.1 UniProtKB/TrEMBL
  ENSSSCT00055058574.1 UniProtKB/TrEMBL
  ENSSSCT00055058648.1 UniProtKB/TrEMBL
  ENSSSCT00055058674.1 UniProtKB/TrEMBL
  ENSSSCT00055058751.1 UniProtKB/TrEMBL
  ENSSSCT00060090188.1 UniProtKB/TrEMBL
  ENSSSCT00065060287.1 UniProtKB/TrEMBL
  ENSSSCT00065060309.1 UniProtKB/TrEMBL
  ENSSSCT00065060317.1 UniProtKB/TrEMBL
  ENSSSCT00065060343.1 UniProtKB/TrEMBL
  ENSSSCT00070003270.1 UniProtKB/TrEMBL
  ENSSSCT00070003284.1 UniProtKB/TrEMBL
  ENSSSCT00070003319.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.132.30 UniProtKB/TrEMBL
  1.10.150.390 UniProtKB/TrEMBL
  1.10.274.100 UniProtKB/TrEMBL
  2.40.40.20 UniProtKB/TrEMBL
  4.10.860.120 UniProtKB/TrEMBL
  6.10.250.2940 UniProtKB/TrEMBL
  6.20.50.80 UniProtKB/TrEMBL
  RNA polymerase ii UniProtKB/TrEMBL
InterPro DNA-dir_RpoC_beta_prime UniProtKB/TrEMBL
  RNA_pol_asu UniProtKB/TrEMBL
  RNA_pol_N UniProtKB/TrEMBL
  RNA_pol_Rpb1_1 UniProtKB/TrEMBL
  RNA_pol_Rpb1_3 UniProtKB/TrEMBL
  RNA_pol_Rpb1_3_sf UniProtKB/TrEMBL
  RNA_pol_Rpb1_4 UniProtKB/TrEMBL
  RNA_pol_Rpb1_5 UniProtKB/TrEMBL
  RNA_pol_Rpb1_clamp_domain UniProtKB/TrEMBL
  RNAP_III_Rpc1_C UniProtKB/TrEMBL
  RNAP_III_RPC1_N UniProtKB/TrEMBL
  Rpb1_funnel_sf UniProtKB/TrEMBL
KEGG Report ssc:100156229 UniProtKB/TrEMBL
NCBI Gene POLR3A ENTREZGENE
PANTHER DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 UniProtKB/TrEMBL
  PTHR19376 UniProtKB/TrEMBL
Pfam RNA_pol_Rpb1_1 UniProtKB/TrEMBL
  RNA_pol_Rpb1_2 UniProtKB/TrEMBL
  RNA_pol_Rpb1_3 UniProtKB/TrEMBL
  RNA_pol_Rpb1_4 UniProtKB/TrEMBL
  RNA_pol_Rpb1_5 UniProtKB/TrEMBL
SMART RPOLA_N UniProtKB/TrEMBL
Superfamily-SCOP beta and beta-prime subunits of DNA dependent RNA-polymerase UniProtKB/TrEMBL
UniProt A0A286ZPB2_PIG UniProtKB/TrEMBL
  A0A4X1SJU1 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SK18_PIG UniProtKB/TrEMBL
  A0A4X1SL14_PIG UniProtKB/TrEMBL
  A0A8D1IHA5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IMQ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SC59 ENTREZGENE, UniProtKB/TrEMBL
  F1S2E6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91654 ENTREZGENE