LOC100623616 (arylacetamide deacetylase-like) - Rat Genome Database

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Gene: LOC100623616 (arylacetamide deacetylase-like) Sus scrofa
Analyze
Symbol: LOC100623616 (Ensembl: AADAC)
Name: arylacetamide deacetylase-like (Ensembl:arylacetamide deacetylase)
RGD ID: 14226011
Description: ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); deacetylase activity (inferred); hydrolase activity (inferred); INVOLVED IN positive regulation of triglyceride catabolic process (inferred); ASSOCIATED WITH congenital merosin-deficient muscular dystrophy 1A (ortholog); Experimental Liver Cirrhosis (ortholog); Primary Ovarian Failure (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AADAC; arylacetamide deacetylase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1392,017,548 - 92,042,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11392,017,495 - 92,042,944 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC100623616
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1392,017,548 - 92,042,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11392,017,495 - 92,042,944 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AADAC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383151,814,116 - 151,828,488 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3151,814,073 - 151,828,488 (+)EnsemblGRCh38hg38GRCh38
GRCh373151,531,904 - 151,546,276 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363153,014,551 - 153,028,966 (+)NCBINCBI36Build 36hg18NCBI36
Build 343153,014,563 - 153,028,972NCBI
Celera3149,949,986 - 149,964,402 (+)NCBICelera
Cytogenetic Map3q25.1ENTREZGENE
HuRef3148,922,978 - 148,937,379 (+)NCBIHuRef
CHM1_13151,494,887 - 151,509,289 (+)NCBICHM1_1
T2T-CHM13v2.03154,563,474 - 154,596,308 (+)NCBIT2T-CHM13v2.0
Aadac
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39359,939,209 - 59,947,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl359,933,138 - 59,947,581 (+)EnsemblGRCm39 Ensembl
GRCm38360,031,788 - 60,040,157 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl360,025,717 - 60,040,160 (+)EnsemblGRCm38mm10GRCm38
MGSCv37359,835,710 - 59,844,079 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36360,119,717 - 60,128,086 (+)NCBIMGSCv36mm8
Celera359,714,308 - 59,729,435 (+)NCBICelera
Cytogenetic Map3DNCBI
cM Map329.17NCBI
Aadac
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82146,293,449 - 146,351,061 (+)NCBIGRCr8
mRatBN7.22144,163,436 - 144,186,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2144,135,319 - 144,174,734 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2150,817,634 - 150,828,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02148,941,093 - 148,952,355 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02143,573,547 - 143,584,789 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02150,146,234 - 150,157,480 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2150,146,234 - 150,157,480 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02169,573,785 - 169,590,476 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42149,348,935 - 149,360,181 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12149,298,897 - 149,310,144 (+)NCBI
Celera2138,576,394 - 138,587,634 (+)NCBICelera
Cytogenetic Map2q31NCBI
AADAC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22149,709,407 - 149,724,824 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13149,714,142 - 149,729,559 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03148,820,706 - 148,853,422 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13156,409,104 - 156,423,847 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3156,408,950 - 156,423,847 (+)Ensemblpanpan1.1panPan2
AADAC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12346,339,282 - 46,364,588 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2346,339,466 - 46,363,588 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2346,203,086 - 46,229,054 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02346,968,020 - 46,992,389 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2346,968,171 - 46,992,376 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12346,555,091 - 46,582,165 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02346,609,758 - 46,635,722 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02346,887,325 - 46,911,691 (+)NCBIUU_Cfam_GSD_1.0
Aadac
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560289,772,492 - 89,784,330 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493734952,605 - 62,840 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AADAC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11538,855,753 - 38,870,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1538,855,348 - 38,870,649 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604111,619,884 - 11,634,795 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LOC100623616
298 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 4 2 1
Low 1 1 1 1 1 1
Below cutoff 5 1 2 4 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000053002   ⟹   ENSSSCP00000048673
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1392,017,548 - 92,042,938 (+)Ensembl
RefSeq Acc Id: XM_021069630   ⟹   XP_020925289
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11392,017,495 - 92,042,944 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069631   ⟹   XP_020925290
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11392,021,220 - 92,042,944 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020925289   ⟸   XM_021069630
- Peptide Label: isoform X1
- UniProtKB: A0A8D0JL17 (UniProtKB/TrEMBL),   A0A287AXR4 (UniProtKB/TrEMBL),   A0A4X1ST66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925290   ⟸   XM_021069631
- Peptide Label: isoform X2
- UniProtKB: A0A4X1ST66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000048673   ⟸   ENSSSCT00000053002
Protein Domains
Alpha/beta hydrolase fold-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031367 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005025829 UniProtKB/TrEMBL
  ENSSSCG00015008926 UniProtKB/TrEMBL
  ENSSSCG00025010259 UniProtKB/TrEMBL
  ENSSSCG00030059951 UniProtKB/TrEMBL
  ENSSSCG00035051387 UniProtKB/TrEMBL
  ENSSSCG00040046432 UniProtKB/TrEMBL
  ENSSSCG00045027596 UniProtKB/TrEMBL
  ENSSSCG00050021583 UniProtKB/TrEMBL
  ENSSSCG00055007234 UniProtKB/TrEMBL
  ENSSSCG00060016927 UniProtKB/TrEMBL
  ENSSSCG00065057606 UniProtKB/TrEMBL
  ENSSSCG00070003942 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000053002 ENTREZGENE
  ENSSSCT00000053002.2 UniProtKB/TrEMBL
  ENSSSCT00005040907.1 UniProtKB/TrEMBL
  ENSSSCT00015011761.1 UniProtKB/TrEMBL
  ENSSSCT00025013522.1 UniProtKB/TrEMBL
  ENSSSCT00030083679.1 UniProtKB/TrEMBL
  ENSSSCT00035068442.1 UniProtKB/TrEMBL
  ENSSSCT00040062474.1 UniProtKB/TrEMBL
  ENSSSCT00045046995.1 UniProtKB/TrEMBL
  ENSSSCT00050029068.1 UniProtKB/TrEMBL
  ENSSSCT00055014062.1 UniProtKB/TrEMBL
  ENSSSCT00060022599.1 UniProtKB/TrEMBL
  ENSSSCT00065078822.1 UniProtKB/TrEMBL
  ENSSSCT00070007400.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_3 UniProtKB/TrEMBL
  Arylacetamide_deacetylase UniProtKB/TrEMBL
NCBI Gene LOC100623616 ENTREZGENE
PANTHER ARYLACETAMIDE DEACETYLASE UniProtKB/TrEMBL
  ARYLACETAMIDE DEACETYLASE UniProtKB/TrEMBL
Pfam Abhydrolase_3 UniProtKB/TrEMBL
PIRSF Arylacetamide_deacetylase UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A287AXR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1ST66 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JL17 ENTREZGENE, UniProtKB/TrEMBL