NXPH4 (neurexophilin 4) - Rat Genome Database

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Gene: NXPH4 (neurexophilin 4) Sus scrofa
Analyze
Symbol: NXPH4
Name: neurexophilin 4
RGD ID: 14221230
Description: ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN modulation of chemical synaptic transmission (ortholog); ASSOCIATED WITH familial melanoma (ortholog); FOUND IN GABA-ergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurexophilin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,522,952 - 22,531,660 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,522,932 - 22,536,614 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,357,067 - 24,366,467 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
NXPH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,522,952 - 22,531,660 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,522,932 - 22,536,614 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,357,067 - 24,366,467 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NXPH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,216,794 - 57,226,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,216,794 - 57,226,449 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,610,577 - 57,620,232 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,896,845 - 55,906,493 (+)NCBINCBI36Build 36hg18NCBI36
Build 341255,896,844 - 55,906,493NCBI
Celera1257,272,891 - 57,274,464 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,657,541 - 54,659,114 (+)NCBIHuRef
CHM1_11257,578,686 - 57,588,330 (+)NCBICHM1_1
T2T-CHM13v2.01257,185,042 - 57,194,687 (+)NCBIT2T-CHM13v2.0
Nxph4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,361,342 - 127,370,428 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,361,342 - 127,370,428 (-)EnsemblGRCm39 Ensembl
GRCm3810127,525,473 - 127,534,559 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,525,473 - 127,534,559 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,962,529 - 126,971,615 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,928,422 - 126,937,508 (-)NCBIMGSCv36mm8
Celera10129,917,315 - 129,926,396 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.51NCBI
Nxph4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,253,043 - 65,261,864 (-)NCBIGRCr8
mRatBN7.2763,367,758 - 63,376,579 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,367,761 - 63,376,579 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx765,257,030 - 65,265,843 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,459,457 - 67,468,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,260,672 - 67,269,477 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,833,662 - 70,842,523 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,833,663 - 70,842,405 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,006,677 - 71,014,869 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,502,668 - 67,516,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,523,398 - 67,537,569 (-)NCBI
Celera760,506,773 - 60,515,544 (-)NCBICelera
Cytogenetic Map7q22NCBI
Nxph4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,949,679 - 4,954,627 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,949,679 - 4,954,627 (+)NCBIChiLan1.0ChiLan1.0
NXPH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,115,242 - 37,124,840 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,112,012 - 37,121,609 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,700,935 - 31,710,526 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,953,259 - 31,962,757 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,953,259 - 31,962,757 (-)Ensemblpanpan1.1panPan2
LOC607393
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,348,634 - 1,353,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,352,470 - 1,353,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,412,351 - 1,417,677 (+)NCBIDog10K_Boxer_Tasha
Nxph4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,448,852 - 57,459,298 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,410,931 - 1,421,531 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,410,937 - 1,421,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NXPH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,128,704 - 53,138,272 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,128,863 - 53,137,569 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,834,187 - 192,843,757 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nxph4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,722,548 - 10,731,500 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,722,011 - 10,731,569 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NXPH4
112 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system hemolymphoid system nervous system
High
Medium
Low 15
Below cutoff 3 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000039987   ⟹   ENSSSCP00000043146
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl522,522,952 - 22,531,660 (+)Ensembl
RefSeq Acc Id: XM_003355482   ⟹   XP_003355530
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1522,522,932 - 22,536,614 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003355530   ⟸   XM_003355482
- UniProtKB: A0A287AH12 (UniProtKB/TrEMBL),   A0A4X1W7Z8 (UniProtKB/TrEMBL),   A0A8D0JMD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000043146   ⟸   ENSSSCT00000039987


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039966 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005028598 UniProtKB/TrEMBL
  ENSSSCG00015068178 UniProtKB/TrEMBL
  ENSSSCG00025017336 UniProtKB/TrEMBL
  ENSSSCG00030047909 UniProtKB/TrEMBL
  ENSSSCG00035057948 UniProtKB/TrEMBL
  ENSSSCG00040010857 UniProtKB/TrEMBL
  ENSSSCG00045032420 UniProtKB/TrEMBL
  ENSSSCG00050008223 UniProtKB/TrEMBL
  ENSSSCG00055017664 UniProtKB/TrEMBL
  ENSSSCG00060053809 UniProtKB/TrEMBL
  ENSSSCG00065020088 UniProtKB/TrEMBL
  ENSSSCG00070029171 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000039987.2 UniProtKB/TrEMBL
  ENSSSCT00005045314.1 UniProtKB/TrEMBL
  ENSSSCT00015091344.1 UniProtKB/TrEMBL
  ENSSSCT00025023409.1 UniProtKB/TrEMBL
  ENSSSCT00030066882.1 UniProtKB/TrEMBL
  ENSSSCT00035077518.1 UniProtKB/TrEMBL
  ENSSSCT00040014146.1 UniProtKB/TrEMBL
  ENSSSCT00045055352.1 UniProtKB/TrEMBL
  ENSSSCT00050011195.1 UniProtKB/TrEMBL
  ENSSSCT00055034644.1 UniProtKB/TrEMBL
  ENSSSCT00060073253.1 UniProtKB/TrEMBL
  ENSSSCT00065026761.1 UniProtKB/TrEMBL
  ENSSSCT00070058550.1 UniProtKB/TrEMBL
InterPro Nxph UniProtKB/TrEMBL
  NXPH/NXPE UniProtKB/TrEMBL
NCBI Gene NXPH4 ENTREZGENE
PANTHER NEUREXOPHILIN-4 UniProtKB/TrEMBL
  PTHR17103 UniProtKB/TrEMBL
Pfam Neurexophilin UniProtKB/TrEMBL
PIRSF Neurexophilin UniProtKB/TrEMBL
UniProt A0A287AH12 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W7Z8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JMD3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91000 ENTREZGENE