LOC607393 (neurexophilin-4) - Rat Genome Database

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Gene: LOC607393 (neurexophilin-4) Canis lupus familiaris
Analyze
Symbol: LOC607393 (Ensembl: NXPH4)
Name: neurexophilin-4 (Ensembl:neurexophilin 4)
RGD ID: 12360724
Description: INVOLVED IN modulation of chemical synaptic transmission (ortholog); ASSOCIATED WITH familial melanoma (ortholog); FOUND IN GABA-ergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurexophilin 4; NXPH4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: not annotated on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,348,634 - 1,353,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,352,470 - 1,353,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,412,351 - 1,417,677 (+)NCBIDog10K_Boxer_Tasha
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Genomics

Comparative Map Data
LOC607393
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,348,634 - 1,353,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,352,470 - 1,353,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,412,351 - 1,417,677 (+)NCBIDog10K_Boxer_Tasha
NXPH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,216,794 - 57,226,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,216,794 - 57,226,449 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,610,577 - 57,620,232 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,896,845 - 55,906,493 (+)NCBINCBI36Build 36hg18NCBI36
Build 341255,896,844 - 55,906,493NCBI
Celera1257,272,891 - 57,274,464 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,657,541 - 54,659,114 (+)NCBIHuRef
CHM1_11257,578,686 - 57,588,330 (+)NCBICHM1_1
T2T-CHM13v2.01257,185,042 - 57,194,687 (+)NCBIT2T-CHM13v2.0
Nxph4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,361,342 - 127,370,428 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,361,342 - 127,370,428 (-)EnsemblGRCm39 Ensembl
GRCm3810127,525,473 - 127,534,559 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,525,473 - 127,534,559 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,962,529 - 126,971,615 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,928,422 - 126,937,508 (-)NCBIMGSCv36mm8
Celera10129,917,315 - 129,926,396 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.51NCBI
Nxph4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,253,043 - 65,261,864 (-)NCBIGRCr8
mRatBN7.2763,367,758 - 63,376,579 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,367,761 - 63,376,579 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx765,257,030 - 65,265,843 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,459,457 - 67,468,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,260,672 - 67,269,477 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,833,662 - 70,842,523 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,833,663 - 70,842,405 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,006,677 - 71,014,869 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,502,668 - 67,516,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,523,398 - 67,537,569 (-)NCBI
Celera760,506,773 - 60,515,544 (-)NCBICelera
Cytogenetic Map7q22NCBI
Nxph4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,949,679 - 4,954,627 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,949,679 - 4,954,627 (+)NCBIChiLan1.0ChiLan1.0
NXPH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,115,242 - 37,124,840 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,112,012 - 37,121,609 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,700,935 - 31,710,526 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,953,259 - 31,962,757 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,953,259 - 31,962,757 (-)Ensemblpanpan1.1panPan2
Nxph4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,448,852 - 57,459,298 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,410,931 - 1,421,531 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,410,937 - 1,421,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NXPH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,522,952 - 22,531,660 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,522,932 - 22,536,614 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,357,067 - 24,366,467 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NXPH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,128,704 - 53,138,272 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,128,863 - 53,137,569 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,834,187 - 192,843,757 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nxph4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,722,548 - 10,731,500 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,722,011 - 10,731,569 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC607393
44 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 1
Low 10 4 6 8 1 3
Below cutoff 4 5 11 6 2 6 1 3 6 6 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000046425   ⟹   ENSCAFP00000039566
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl101,352,470 - 1,353,321 (+)Ensembl
RefSeq Acc Id: XM_038632207   ⟹   XP_038488135
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha101,412,351 - 1,417,677 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038488135 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000039566.3
  ENSCAFP00030016669.1
  ENSCAFP00040018473.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000039566   ⟸   ENSCAFT00000046425
RefSeq Acc Id: XP_038488135   ⟸   XM_038632207


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029507 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010358 UniProtKB/TrEMBL
  ENSCAFG00040011511 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046425.3 UniProtKB/TrEMBL
  ENSCAFT00030019110.1 UniProtKB/TrEMBL
  ENSCAFT00040021271.1 UniProtKB/TrEMBL
InterPro Nxph UniProtKB/TrEMBL
  NXPH/NXPE UniProtKB/TrEMBL
NCBI Gene NXPH4 ENTREZGENE
PANTHER NEUREXOPHILIN-4 UniProtKB/TrEMBL
  PTHR17103 UniProtKB/TrEMBL
Pfam Neurexophilin UniProtKB/TrEMBL
PIRSF Neurexophilin UniProtKB/TrEMBL
UniProt A0A8C0SAB7_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC607393  neurexophilin-4  NXPH4  neurexophilin 4  Symbol and/or name change 5135510 APPROVED