LOC100522887 (caspase-13) - Rat Genome Database

Name: LOC100522887
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: LOC100522887 (caspase-13) Sus scrofa

Analyze

Symbol:

LOC100522887

Name:

caspase-13

RGD ID:

14203920

Description:

ENCODES a protein that exhibits CARD domain binding (ortholog); lipid binding (ortholog); lipopolysaccharide binding (ortholog); INVOLVED IN cellular response to amyloid-beta (ortholog); defense response to bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); ASSOCIATED WITH ataxia telangiectasia (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); COVID-19 (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

CASP4; caspase 4, apoptosis-related cysteine peptidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CASP4 (caspase 4)	HGNC	Ensembl, Inparanoid, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Casp4 (caspase 4, apoptosis-related cysteine peptidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Casp4 (caspase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CASP4 (caspase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CASP4 (caspase 4, apoptosis-related cysteine peptidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103248367 (caspase-4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Casp4 (caspase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CASP5 (caspase 5)	HGNC	Ensembl, Panther, Treefam

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	35,167,567 - 35,185,791 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	39,189,534 - 39,208,073 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ataxia telangiectasia (ISO)

Chromosome 11, Partial Trisomy 11q (ISO)

COVID-19 (ISO)

Experimental Liver Cirrhosis (ISO)

intellectual disability (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IBA)

cellular response to amyloid-beta (ISO)

defense response to bacterium (ISO)

defense response to Gram-positive bacterium (ISO)

detection of lipopolysaccharide (ISO)

ectopic germ cell programmed cell death (ISO)

intrinsic apoptotic signaling pathway (ISO)

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ISO)

non-canonical inflammasome complex assembly (ISO)

positive regulation of inflammatory response (IBA)

positive regulation of interleukin-1 beta production (ISO)

positive regulation of interleukin-18-mediated signaling pathway (ISO)

positive regulation of macrophage cytokine production (ISO)

positive regulation of neuron apoptotic process (IBA)

positive regulation of NLRP3 inflammasome complex assembly (ISO)

positive regulation of tumor necrosis factor-mediated signaling pathway (ISO)

protein autoprocessing (ISO)

protein maturation (ISO)

proteolysis (IEA)

pyroptotic inflammatory response (ISO)

regulation of apoptotic process (IEA)

regulation of inflammatory response (IEA)

Cellular Component

AIM2 inflammasome complex (IEA)

cytoplasm (IBA)

cytosol (ISO)

endoplasmic reticulum (ISO)

IPAF inflammasome complex (IEA)

mitochondrion (ISO)

neuronal cell body (ISO)

NLRP1 inflammasome complex (IBA)

NLRP3 inflammasome complex (IEA)

non-canonical inflammasome complex (ISO)

plasma membrane (ISO)

protein-containing complex (ISO)

Molecular Function

CARD domain binding (ISO)

caspase binding (IEA)

cysteine-type endopeptidase activity (IBA,IEA)

cysteine-type endopeptidase activity involved in apoptotic process (IBA)

cysteine-type peptidase activity (IEA)

lipid binding (ISO)

lipopolysaccharide binding (ISO)

protein binding (ISO)

scaffold protein binding (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC100522887
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	35,167,567 - 35,185,791 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	39,189,534 - 39,208,073 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CASP4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	104,942,866 - 104,968,574 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	104,942,866 - 104,969,366 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	104,813,593 - 104,839,301 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	104,318,804 - 104,344,535 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	104,318,804 - 104,344,503	NCBI
Celera	11	101,977,781 - 102,003,518 (-)	NCBI		Celera
Cytogenetic Map	11	q22.3	NCBI
HuRef	11	100,744,534 - 100,770,269 (-)	NCBI		HuRef
CHM1_1	11	104,696,522 - 104,722,254 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	104,946,956 - 104,972,673 (-)	NCBI		T2T-CHM13v2.0

Casp4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	5,308,816 - 5,336,791 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	5,308,828 - 5,336,783 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	5,308,849 - 5,336,791 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	5,308,828 - 5,336,783 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	5,308,860 - 5,336,791 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	5,308,874 - 5,336,717 (+)	NCBI		MGSCv36	mm8
Celera	3	117,367,159 - 117,395,096 (-)	NCBI		Celera
Cytogenetic Map	9	A1	NCBI
cM Map	9	2.46	NCBI

Casp4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	10,883,817 - 10,919,978 (+)	NCBI		GRCr8
mRatBN7.2	8	2,599,017 - 2,635,097 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	2,598,876 - 2,635,092 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	6,570,604 - 6,598,288 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	4,868,372 - 4,896,060 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	2,851,833 - 2,886,754 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	2,616,391 - 2,651,682 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	2,635,851 - 2,651,652 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	2,638,624 - 2,673,915 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	2,038,626 - 2,075,722 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	2,038,610 - 2,075,144 (+)	NCBI
Celera	8	4,218,310 - 4,234,223 (+)	NCBI		Celera
Cytogenetic Map	8	q11	NCBI

CASP4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	105,734,010 - 105,759,789 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	106,822,318 - 106,848,104 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	99,883,353 - 99,909,185 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	103,366,138 - 103,391,849 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	103,366,138 - 103,391,824 (-)	Ensembl	panpan1.1		panPan2

CASP4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	27,133,778 - 27,147,954 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	27,132,565 - 27,149,736 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	27,064,601 - 27,078,777 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	27,170,519 - 27,184,696 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	27,169,891 - 27,186,517 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	27,212,077 - 27,226,245 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	27,098,364 - 27,112,532 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	27,257,464 - 27,271,644 (+)	NCBI		UU_Cfam_GSD_1.0

LOC103248367
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	96,315,781 - 96,342,057 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	96,315,569 - 96,342,016 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	29,555,456 - 29,581,392 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Casp4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624918	145,661 - 187,006 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LOC100522887
607 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	10	2	1	5	1	7		3	3
Low		2	2		1	16	2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003129812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK231138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK344410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK391544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK396340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBZA01000094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01015232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_003129812 ⟹ XP_003129860

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	9	35,167,567 - 35,185,791 (-)	NCBI

Sequence:

show sequence

TAGATGAGCAGAGGAATACTGAGAGATCAGAAGGAGAAGAACAGAGAGAGAGAGGGAAGTGTGA
GGCAATGAGGAAAGAAAAAGAAAAGGGAGAAAACACTCCACCGATCCAAAGTAGGTTAGGCTAT
GTTTTTTTTTTGGTCAATTTTTTTCTTCCTAGAGGAAGAAATCCACTTGCTGACTACAGGGGAC
TTCCCGGCAGGGAACCCAGAAGTTCTGAGCAGCAGTTTCCCAATCTATGATTAGAAGTCCCCGC
CTCCCGAACTAAGGAAATTAGTAGTTTCATTTTCAAGCCTGTGCTCTCCTCAAGGCAGCAGGAA
GGGACTGAGGCTGTTACCTATGGCTGAAGTCAAACAAAAAAAAAACCCACTGAAGATTTTGGAA
TCTATGGGAAAAGAACTCATTACTGGAGTTTTGGATGATTTGGTGGAAAAAGATGTTCTGAAAC
TGGAAGAAGAGGAGAAGAAAAATATTTATGATGCCAAACTTCAAGACAAGGCCCGGATCTTGAT
GGACTCTGTGCTACAGAAACGCCATGAGGCAAGTCAAGTCTTTGTTAAAACCTTCCTTAACATG
GACAAAAATTCCACCAGCATACAAGCTCCCGAGAAAATCATGGCTGGACCAGATGAGTCAGAAG
AATCTACTGATACCCTCAAGCTTTGCCCTCATGAAGAATTCCTGAAACTGTGTAAAGAAAGGAC
TGGAGAGATCTATCCAATAAAAAATAAAAATGACCGCACTCGTCTGGCTCTCATCATATGCAAT
ACAAAGTTTGATCATCTTCCTCTCAGGAATGGGGCTGACCTCGACATTAAGGGAATGAGGGGGC
TGCTTGAGGGCCTTGGCTACAGTGTGGATGTGGAAGAGAAACTCACGGCCAAGGAGATGGAATC
GGTGCTGTGGGGGTTTGCTGCCCGCCAAGAGCACAAGTCTTCAGACAGCACATTCTTAGTGTTC
ATGTCTCATGGCATCCTGGATGGGATCTGTGGGACTATGCATAGTGATAAAAAACCAGATGTGC
TACATTATGACACCATCTTCAAGATATTCAACAACCGCAACTGCCTCGGTCTGAAGGACAAACC
TAAGGTCATCATTGTCCAGGCCTGCAGAGGTGCAAATCGTGGAGAAGTGTGGGTCAGTGACTCT
CCAGCAACCTTGGCAGACAGCTCTTCAGAGTCACCTGAGGACCTGGAGGAGGATGCCGTTTACA
AGACCCATGTGGAGAAGGACTTCATCGCTTTTTGCTCTTCAACACCACATAATGTGTCCTGGAG
AGATGTCACAAAGGGTTCTCTCTTCATCACACAACTCATCACTTGCTTCNAAAAATATGCTTGG
CGCTGTCACCTAGAGGAAGTATTTAGGAAGGTACAACAATCATTTGAAACACCAAGCGTTAAAG
CCCAGATGCCCACCATTGAACGACTCTCCATGACAAGATATTTCTACCTCTTTCCTGGCAATTG
AGAAAAAAAATCACAGACAGTCTAGCCCTTTACCAACTTTGAGAAGCACCATTACCAGCACAGC
ACATATGTTTAACATTTTGTCTTTCAGTGTAAATGAAAAACAACGTTTTTTGTGTGTGTGTCTT
CTAATAGAGAAGAGAATTTCAATTAAAATGGTGGATAATGGAAATGAAATGGAAGAAGTGAGCT
GGATTTTTCTGATTATGACATAATATCTGCACTTTACTGAGTGAAGGGAACTGGCCGTGGCTTG
CTCTCAGCAACAAGGTGGAAGGAGATGGTGCCCATCTAGAGACAAGAATTATAAACCGATCAGC
TCCTCCTTGTGCACTCATCTAACCTGGGGTCTAGAATTTCCAAAAGAAGTTTTCTAATTTATTA
TTTAGCCAACATCATAGCTGGAGCTCTTTTTTTTCTTCACTAAGTTATTATGCTTTTAGCAAAT
TATACTATGTATCTATCTTTCTTCCTACCTATAAGATAATTCACTTTCTTGTTGCTTATTTTCT
TTCCAGATTTATGCATATTTCCAAGCTTCAGGAGAATTTTTTACTTAGCAAACACTGGGTCATT
GTCCAAAATAAATTGGGCTTCTGATTCAAGATGGTGTAACCTGAATGTATCTGTATAGAAAGAA
AAGTATTATTAATAAAGAATAGCCAAAATGGCAGTGTCAACAGTGGGAGACAGGATGTTAAAAT
TTCTGGAAAGGTGAAATTTCTAGAGGAATTTTGGCAACATGGCTTCTGAGTTACTAAGTAATGA
AATGTACCACTTCTGCTACATACACAGAATGCTGAATAAATATTTTAGTACGTGCTAAACTGCA
TTAAACATAAAATGATTCTCTATGTGTCAAATATAACCATAATAGTTAATATTTATTACTGTGT
GTCAGGATTATTTCAAGAATTTTTATTACTCTAAGGGACTTTGAATAAATAAGTAGCTACTTTA
ACCTTCACAACAGCCCTGCAATGTAATCACTATCAATATCCCCATCTTACAGATAATGAAACTA
AAGAAAATAGAGCTTAAGTGATGTGCCCAAAGTCCCACAGTTAGTAGGTGGTTGCACTGGCATT
TGAATGCAGTCTGACTTGCTCTGCAATCTGAGATGTTAACCACTGTACTGCATTGCCTCCCCAA
GGCAAGGAGAGAATGAAATTGTATGCGTTTTAAATTGTAAGGGTTGGGATTTCCATTGTGGCTC
AGTGGAAATAAATCTGACTGGCATTCATGAGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003129860	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000015922
	ENSSSCP00000015922.4
	ENSSSCP00035013871.1
	ENSSSCP00040019607.1
	ENSSSCP00050014775.1
	ENSSSCP00055013735.1
GenBank Protein	JAG69674	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_003129860 ⟸ XM_003129812

- UniProtKB:

A0A8D1K9R7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEVKQKKNPLKILESMGKELITGVLDDLVEKDVLKLEEEEKKNIYDAKLQDKARILMDSVLQK
RHEASQVFVKTFLNMDKNSTSIQAPEKIMAGPDESEESTDTLKLCPHEEFLKLCKERTGEIYPI
KNKNDRTRLALIICNTKFDHLPLRNGADLDIKGMRGLLEGLGYSVDVEEKLTAKEMESVLWGFA
ARQEHKSSDSTFLVFMSHGILDGICGTMHSDKKPDVLHYDTIFKIFNNRNCLGLKDKPKVIIVQ
ACRGANRGEVWVSDSPATLADSSSESPEDLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDVTKGS
LFITQLITCFXKYAWRCHLEEVFRKVQQSFETPSVKAQMPTIERLSMTRYFYLFPGN

hide sequence

Protein Domains

CARD Caspase family p10 Caspase family p20

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000014997	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00035026513	UniProtKB/TrEMBL
	ENSSSCG00040034768	UniProtKB/TrEMBL
	ENSSSCG00050026429	UniProtKB/TrEMBL
	ENSSSCG00055008882	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000016361	ENTREZGENE
	ENSSSCT00000016361.5	UniProtKB/TrEMBL
	ENSSSCT00035034992.1	UniProtKB/TrEMBL
	ENSSSCT00040046768.1	UniProtKB/TrEMBL
	ENSSSCT00050035561.1	UniProtKB/TrEMBL
	ENSSSCT00055017371.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.533.10	UniProtKB/TrEMBL
	3.40.50.1460	UniProtKB/TrEMBL
InterPro	CARD	UniProtKB/TrEMBL
	Caspase-like_dom_sf	UniProtKB/TrEMBL
	Caspase_cys_AS	UniProtKB/TrEMBL
	Caspase_his_AS	UniProtKB/TrEMBL
	DEATH-like_dom_sf	UniProtKB/TrEMBL
	Pept_C14_caspase	UniProtKB/TrEMBL
	Pept_C14_p10	UniProtKB/TrEMBL
	Pept_C14_p20	UniProtKB/TrEMBL
	Pept_C14A	UniProtKB/TrEMBL
KEGG Report	ssc:100522887	UniProtKB/TrEMBL
NCBI Gene	LOC100522887	ENTREZGENE
PANTHER	CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18	UniProtKB/TrEMBL
	CASPASE-1	UniProtKB/TrEMBL
Pfam	CARD	UniProtKB/TrEMBL
	Peptidase_C14	UniProtKB/TrEMBL
PIRSF	Caspase_ICE	UniProtKB/TrEMBL
PRINTS	IL1BCENZYME	UniProtKB/TrEMBL
PROSITE	CARD	UniProtKB/TrEMBL
	CASPASE_CYS	UniProtKB/TrEMBL
	CASPASE_HIS	UniProtKB/TrEMBL
	CASPASE_P10	UniProtKB/TrEMBL
	CASPASE_P20	UniProtKB/TrEMBL
SMART	CARD	UniProtKB/TrEMBL
	CASc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47986	UniProtKB/TrEMBL
	SSF52129	UniProtKB/TrEMBL
UniProt	A0A8D1K9R7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1LWG5_PIG	UniProtKB/TrEMBL
	F1SV36_PIG	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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