SLC4A10 (solute carrier family 4 member 10) - Rat Genome Database

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Gene: SLC4A10 (solute carrier family 4 member 10) Sus scrofa
Analyze
Symbol: SLC4A10
Name: solute carrier family 4 member 10
RGD ID: 14122941
Description: ENCODES a protein that exhibits monoatomic anion transmembrane transporter activity (inferred); secondary active transmembrane transporter activity (inferred); sodium,bicarbonate:chloride antiporter activity (inferred); INVOLVED IN brain morphogenesis (ortholog); locomotory exploration behavior (ortholog); multicellular organism growth (ortholog); ASSOCIATED WITH autistic disorder (ortholog); cognitive disorder (ortholog); epilepsy (ortholog); FOUND IN apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium-driven chloride bicarbonate exchanger
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1568,224,395 - 68,656,309 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11568,342,607 - 68,655,009 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21575,988,553 - 76,105,143 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC4A10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1568,224,395 - 68,656,309 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11568,342,607 - 68,655,009 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21575,988,553 - 76,105,143 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC4A10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382161,624,416 - 161,985,270 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2161,424,332 - 161,985,282 (+)EnsemblGRCh38hg38GRCh38
GRCh372162,480,926 - 162,841,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362162,189,091 - 162,550,032 (+)NCBINCBI36Build 36hg18NCBI36
Build 342162,306,452 - 162,665,750NCBI
Celera2156,091,092 - 156,452,030 (+)NCBICelera
Cytogenetic Map2q24.2NCBI
HuRef2154,363,681 - 154,723,673 (+)NCBIHuRef
CHM1_12162,486,707 - 162,847,707 (+)NCBICHM1_1
T2T-CHM13v2.02162,077,534 - 162,441,869 (+)NCBIT2T-CHM13v2.0
Slc4a10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39261,876,815 - 62,157,087 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl261,876,806 - 62,157,074 (+)EnsemblGRCm39 Ensembl
GRCm38262,046,472 - 62,326,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl262,046,462 - 62,326,730 (+)EnsemblGRCm38mm10GRCm38
MGSCv37261,884,597 - 62,164,800 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36261,847,433 - 62,127,565 (+)NCBIMGSCv36mm8
Celera263,750,240 - 64,018,815 (+)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map235.79NCBI
Slc4a10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8367,050,925 - 67,367,637 (+)NCBIGRCr8
mRatBN7.2346,665,076 - 46,959,088 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl346,665,265 - 46,957,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx350,018,426 - 50,311,930 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0358,601,943 - 58,895,450 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0356,375,154 - 56,668,478 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0347,995,812 - 48,287,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl347,995,959 - 48,287,910 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0354,662,196 - 54,953,988 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4343,979,103 - 44,274,283 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1343,875,474 - 44,170,655 (+)NCBI
Celera346,306,173 - 46,598,361 (+)NCBICelera
Cytogenetic Map3q21NCBI
Slc4a10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544911,879,016 - 12,160,065 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544911,879,070 - 12,159,981 (-)NCBIChiLan1.0ChiLan1.0
SLC4A10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21364,199,897 - 64,677,338 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B64,214,868 - 64,692,313 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B48,917,958 - 49,278,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B166,287,216 - 166,647,560 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B166,371,645 - 166,647,554 (+)Ensemblpanpan1.1panPan2
SLC4A10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1367,106,897 - 7,392,275 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl367,106,994 - 7,390,398 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha367,248,181 - 7,533,847 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0367,235,661 - 7,521,757 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl367,235,750 - 7,521,041 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1367,251,947 - 7,536,970 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0367,295,870 - 7,581,750 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0367,404,242 - 7,689,637 (+)NCBIUU_Cfam_GSD_1.0
Slc4a10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303124,268,167 - 124,549,520 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646917,068,175 - 17,349,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646917,068,179 - 17,349,563 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC4A10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11047,029,924 - 47,390,116 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1047,030,231 - 47,390,123 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040152,134,807 - 152,512,388 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc4a10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247323,540,954 - 3,849,863 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247323,541,525 - 3,849,805 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC4A10
4947 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system reproductive system respiratory system
High
Medium 20 1
Low 1
Below cutoff 4 3 3 4 1 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017305   ⟹   ENSSSCP00000016842
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1568,342,829 - 68,633,948 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000023989   ⟹   ENSSSCP00000023937
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1568,342,692 - 68,655,000 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000027600   ⟹   ENSSSCP00000025934
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1568,224,395 - 68,654,979 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000060616   ⟹   ENSSSCP00000043054
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1568,449,363 - 68,656,309 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000096429   ⟹   ENSSSCP00000079024
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1568,342,692 - 68,652,915 (+)Ensembl
RefSeq Acc Id: XM_021075903   ⟹   XP_020931562
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11568,342,607 - 68,655,009 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020931562   ⟸   XM_021075903
- UniProtKB: A0A8D0VXD6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000043054   ⟸   ENSSSCT00000060616
RefSeq Acc Id: ENSSSCP00000016842   ⟸   ENSSSCT00000017305
RefSeq Acc Id: ENSSSCP00000025934   ⟸   ENSSSCT00000027600
RefSeq Acc Id: ENSSSCP00000023937   ⟸   ENSSSCT00000023989
RefSeq Acc Id: ENSSSCP00000079024   ⟸   ENSSSCT00000096429
Protein Domains
Band 3 cytoplasmic   Bicarbonate transporter-like transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015893 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030018914 UniProtKB/TrEMBL
  ENSSSCG00040072441 UniProtKB/TrEMBL
  ENSSSCG00060007829 UniProtKB/TrEMBL
  ENSSSCG00065077204 UniProtKB/TrEMBL
  ENSSSCG00070025644 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017305.5 UniProtKB/TrEMBL
  ENSSSCT00000023989 ENTREZGENE
  ENSSSCT00000023989.4 UniProtKB/TrEMBL
  ENSSSCT00000027600.4 UniProtKB/TrEMBL
  ENSSSCT00000060616.3 UniProtKB/TrEMBL
  ENSSSCT00000096429.1 UniProtKB/TrEMBL
  ENSSSCT00030026170.1 UniProtKB/TrEMBL
  ENSSSCT00030026178.1 UniProtKB/TrEMBL
  ENSSSCT00040100553.1 UniProtKB/TrEMBL
  ENSSSCT00040100647.1 UniProtKB/TrEMBL
  ENSSSCT00060010038.1 UniProtKB/TrEMBL
  ENSSSCT00060010042.1 UniProtKB/TrEMBL
  ENSSSCT00065106837.1 UniProtKB/TrEMBL
  ENSSSCT00065106864.1 UniProtKB/TrEMBL
  ENSSSCT00070051426.1 UniProtKB/TrEMBL
  ENSSSCT00070051427.1 UniProtKB/TrEMBL
  ENSSSCT00070051428.1 UniProtKB/TrEMBL
  ENSSSCT00070051429.1 UniProtKB/TrEMBL
  ENSSSCT00070051431.1 UniProtKB/TrEMBL
  ENSSSCT00070051432.1 UniProtKB/TrEMBL
  ENSSSCT00070051433.1 UniProtKB/TrEMBL
  ENSSSCT00070051434.1 UniProtKB/TrEMBL
Gene3D-CATH Helical hairpin bin UniProtKB/TrEMBL
InterPro Band3_cytoplasmic_dom UniProtKB/TrEMBL
  HCO3_transpt_C UniProtKB/TrEMBL
  HCO3_transpt_euk UniProtKB/TrEMBL
  Na/HCO3_transpt UniProtKB/TrEMBL
  PTrfase/Anion_transptr UniProtKB/TrEMBL
NCBI Gene SLC4A10 ENTREZGENE
PANTHER PTHR11453 UniProtKB/TrEMBL
  SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER UniProtKB/TrEMBL
Pfam Band_3_cyto UniProtKB/TrEMBL
  HCO3_cotransp UniProtKB/TrEMBL
PRINTS HCO3TRNSPORT UniProtKB/TrEMBL
  NAHCO3TRSPRT UniProtKB/TrEMBL
Superfamily-SCOP SSF55804 UniProtKB/TrEMBL
UniProt A0A287AGF6_PIG UniProtKB/TrEMBL
  A0A4X1VJ42_PIG UniProtKB/TrEMBL
  A0A4X1VJ48_PIG UniProtKB/TrEMBL
  A0A4X1VN83_PIG UniProtKB/TrEMBL
  A0A4X1VN87_PIG UniProtKB/TrEMBL
  A0A4X1VNV3_PIG UniProtKB/TrEMBL
  A0A4X1VNV9_PIG UniProtKB/TrEMBL
  A0A4X1VPP0_PIG UniProtKB/TrEMBL
  A0A4X1VPP5_PIG UniProtKB/TrEMBL
  A0A5K1UQT2_PIG UniProtKB/TrEMBL
  A0A5K1UQT4_PIG UniProtKB/TrEMBL
  A0A8D0VXD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FIH4_PIG UniProtKB/TrEMBL
  F1RPQ2_PIG UniProtKB/TrEMBL
UniProt Secondary I3LIN1 UniProtKB/TrEMBL
  I3LPA8 UniProtKB/TrEMBL
VGNC ID VGNC:95592 ENTREZGENE