MNS1 (meiosis specific nuclear structural 1) - Rat Genome Database

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Gene: MNS1 (meiosis specific nuclear structural 1) Sus scrofa
Analyze
Symbol: MNS1
Name: meiosis specific nuclear structural 1
RGD ID: 14011235
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN cilium organization (ortholog); left/right axis specification (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Visceral Heterotaxy 9, Autosomal (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: meiosis-specific nuclear structural protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1115,471,922 - 115,553,524 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11115,471,904 - 115,526,344 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21127,766,386 - 127,821,073 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MNS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1115,471,922 - 115,553,524 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11115,471,904 - 115,526,344 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21127,766,386 - 127,821,073 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MNS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381556,428,724 - 56,465,137 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1556,421,544 - 56,465,137 (-)EnsemblGRCh38hg38GRCh38
GRCh371556,720,922 - 56,757,335 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361554,508,299 - 54,544,627 (-)NCBINCBI36Build 36hg18NCBI36
Celera1533,609,956 - 33,646,382 (-)NCBICelera
Cytogenetic Map15q21.3NCBI
HuRef1533,544,043 - 33,580,471 (-)NCBIHuRef
CHM1_11556,839,205 - 56,875,585 (-)NCBICHM1_1
T2T-CHM13v2.01554,231,531 - 54,267,997 (-)NCBIT2T-CHM13v2.0
Mns1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39972,345,276 - 72,366,036 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl972,345,293 - 72,369,307 (+)EnsemblGRCm39 Ensembl
GRCm38972,437,821 - 72,458,581 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl972,438,011 - 72,462,025 (+)EnsemblGRCm38mm10GRCm38
MGSCv37972,286,336 - 72,306,383 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36972,217,444 - 72,257,141 (+)NCBIMGSCv36mm8
Celera969,626,514 - 69,646,492 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map940.08NCBI
Mns1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8882,029,587 - 82,050,276 (+)NCBIGRCr8
mRatBN7.2873,148,877 - 73,169,570 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl873,148,877 - 73,176,925 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx878,673,818 - 78,694,551 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0876,946,448 - 76,967,181 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0874,783,843 - 74,804,574 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0879,054,240 - 79,075,119 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl879,054,237 - 79,075,122 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0874,012,277 - 74,033,156 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4877,015,290 - 77,035,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera868,580,276 - 68,600,965 (-)NCBICelera
Cytogenetic Map8q24NCBI
Mns1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545017,819,929 - 17,851,762 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545017,819,812 - 17,852,157 (+)NCBIChiLan1.0ChiLan1.0
MNS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21645,674,576 - 45,727,980 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11549,851,180 - 49,910,848 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01535,377,490 - 35,433,871 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11553,713,815 - 53,750,213 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1553,714,110 - 53,750,050 (-)Ensemblpanpan1.1panPan2
MNS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13021,648,709 - 21,682,650 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3021,649,008 - 21,682,576 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3021,614,035 - 21,647,973 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03021,799,554 - 21,833,500 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3021,798,594 - 21,833,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13021,739,796 - 21,773,734 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03021,823,571 - 21,857,522 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03021,958,214 - 21,992,155 (-)NCBIUU_Cfam_GSD_1.0
Mns1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864099,917,145 - 99,950,471 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647117,770,823 - 17,798,523 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647117,767,063 - 17,798,507 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MNS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12627,026,932 - 27,060,044 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2627,027,827 - 27,059,863 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048114,244,560 - 114,277,775 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mns1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478115,291,416 - 15,328,173 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478115,292,047 - 15,337,466 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MNS1
487 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 5
Low 9 4 5 2 18 2 3 1
Below cutoff 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005082   ⟹   ENSSSCP00000004958
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1115,471,922 - 115,553,524 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000072426   ⟹   ENSSSCP00000071982
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1115,471,922 - 115,526,180 (+)Ensembl
RefSeq Acc Id: XM_013992959   ⟹   XP_013848413
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11115,471,904 - 115,526,344 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013848413   ⟸   XM_013992959
- UniProtKB: A0A4X1TJ85 (UniProtKB/TrEMBL),   A0A5G2RCJ8 (UniProtKB/TrEMBL),   A0A8D0MLF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000004958   ⟸   ENSSSCT00000005082
RefSeq Acc Id: ENSSSCP00000071982   ⟸   ENSSSCT00000072426
Protein Domains
Trichohyalin-plectin-homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004601 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015010772 UniProtKB/TrEMBL
  ENSSSCG00025030486 UniProtKB/TrEMBL
  ENSSSCG00030041911 UniProtKB/TrEMBL
  ENSSSCG00045006519 UniProtKB/TrEMBL
  ENSSSCG00050003663 UniProtKB/TrEMBL
  ENSSSCG00055008638 UniProtKB/TrEMBL
  ENSSSCG00060068091 UniProtKB/TrEMBL
  ENSSSCG00065000502 UniProtKB/TrEMBL
  ENSSSCG00070009416 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005082 ENTREZGENE
  ENSSSCT00000005082.4 UniProtKB/TrEMBL
  ENSSSCT00000072426.1 UniProtKB/TrEMBL
  ENSSSCT00015014160.1 UniProtKB/TrEMBL
  ENSSSCT00025041418.1 UniProtKB/TrEMBL
  ENSSSCT00025041543.1 UniProtKB/TrEMBL
  ENSSSCT00030058294.1 UniProtKB/TrEMBL
  ENSSSCT00030058319.1 UniProtKB/TrEMBL
  ENSSSCT00045010846.1 UniProtKB/TrEMBL
  ENSSSCT00045010881.1 UniProtKB/TrEMBL
  ENSSSCT00050004920.1 UniProtKB/TrEMBL
  ENSSSCT00050004938.1 UniProtKB/TrEMBL
  ENSSSCT00055016879.1 UniProtKB/TrEMBL
  ENSSSCT00055016944.1 UniProtKB/TrEMBL
  ENSSSCT00060092928.1 UniProtKB/TrEMBL
  ENSSSCT00060092945.1 UniProtKB/TrEMBL
  ENSSSCT00065000564.1 UniProtKB/TrEMBL
  ENSSSCT00065000568.1 UniProtKB/TrEMBL
  ENSSSCT00070018282.1 UniProtKB/TrEMBL
  ENSSSCT00070018292.1 UniProtKB/TrEMBL
InterPro MNS1 UniProtKB/TrEMBL
  TPH_dom UniProtKB/TrEMBL
KEGG Report ssc:100621861 UniProtKB/TrEMBL
NCBI Gene MNS1 ENTREZGENE
PANTHER MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 UniProtKB/TrEMBL
  PTHR19265 UniProtKB/TrEMBL
Pfam TPH UniProtKB/TrEMBL
UniProt A0A4X1TJ85 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TJP6_PIG UniProtKB/TrEMBL
  A0A5G2RCJ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MLF5 ENTREZGENE, UniProtKB/TrEMBL
  F1RZG8_PIG UniProtKB/TrEMBL
VGNC ID VGNC:90288 ENTREZGENE