XPR1 (xenotropic and polytropic retrovirus receptor 1) - Rat Genome Database

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Gene: XPR1 (xenotropic and polytropic retrovirus receptor 1) Sus scrofa
Analyze
Symbol: XPR1
Name: xenotropic and polytropic retrovirus receptor 1
RGD ID: 13971899
Description: ENCODES a protein that exhibits phosphate transmembrane transporter activity (ortholog); INVOLVED IN response to virus (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); autosomal recessive chronic granulomatous disease 2 (ortholog); basal ganglia disease (ortholog); FOUND IN cytoplasm (inferred); Golgi apparatus (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: xenotropic and polytropic retrovirus receptor 1 tv1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,237,957 - 122,458,171 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,237,954 - 122,461,669 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,232,141 - 134,329,949 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
XPR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9122,237,957 - 122,458,171 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19122,237,954 - 122,461,669 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29134,232,141 - 134,329,949 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XPR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381180,632,022 - 180,890,279 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1180,632,022 - 180,890,279 (+)EnsemblGRCh38hg38GRCh38
GRCh371180,601,158 - 180,859,415 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361178,867,796 - 179,122,103 (+)NCBINCBI36Build 36hg18NCBI36
Build 341177,332,829 - 177,587,136NCBI
Celera1153,708,013 - 153,966,433 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1151,831,599 - 152,090,309 (+)NCBIHuRef
CHM1_11182,022,943 - 182,282,207 (+)NCBICHM1_1
T2T-CHM13v2.01179,987,035 - 180,245,477 (+)NCBIT2T-CHM13v2.0
Xpr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,151,403 - 155,293,190 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,151,447 - 155,293,161 (-)EnsemblGRCm39 Ensembl
GRCm381155,275,657 - 155,417,444 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,275,701 - 155,417,415 (-)EnsemblGRCm38mm10GRCm38
MGSCv371157,122,787 - 157,264,574 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361157,037,875 - 157,179,662 (-)NCBIMGSCv36mm8
Celera1157,707,719 - 157,849,217 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map166.49NCBI
Xpr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81369,991,517 - 70,136,249 (-)NCBIGRCr8
mRatBN7.21367,441,205 - 67,585,950 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,446,380 - 67,585,946 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1370,031,420 - 70,170,892 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,345,003 - 71,484,322 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01368,606,282 - 68,745,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01372,918,552 - 73,056,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1372,918,490 - 73,056,875 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01377,853,049 - 77,991,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,238,356 - 70,379,254 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11370,252,050 - 70,393,440 (-)NCBI
Celera1367,321,277 - 67,459,182 (-)NCBICelera
Cytogenetic Map13q21NCBI
Xpr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540619,797,245 - 19,974,911 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540619,831,398 - 19,980,994 (+)NCBIChiLan1.0ChiLan1.0
XPR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,880,965 - 69,127,527 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,539,233 - 68,785,782 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,121,029 - 156,367,565 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,789,973 - 160,035,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,790,170 - 160,029,208 (+)Ensemblpanpan1.1panPan2
XPR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1714,165,608 - 14,379,822 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl714,165,608 - 14,379,822 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha713,743,229 - 13,957,574 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0713,892,765 - 14,107,009 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl713,892,765 - 14,107,009 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1713,802,993 - 14,017,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0713,909,599 - 14,123,996 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0714,033,984 - 14,247,810 (+)NCBIUU_Cfam_GSD_1.0
Xpr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934490,610,564 - 90,755,079 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,462,714 - 8,602,185 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,462,714 - 8,601,824 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12548,509,854 - 48,756,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2548,517,525 - 48,756,458 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605549,895,017 - 50,147,454 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xpr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624771942,036 - 1,141,286 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624771941,835 - 1,147,314 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in XPR1
4662 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 2 19 2 2
Low 10 4 3 2 4 3 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016926   ⟹   ENSSSCP00000016473
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9122,237,957 - 122,458,171 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000045586   ⟹   ENSSSCP00000044268
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9122,238,004 - 122,460,535 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000059574   ⟹   ENSSSCP00000033241
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9122,237,979 - 122,454,542 (+)Ensembl
RefSeq Acc Id: XM_003130352   ⟹   XP_003130400
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19122,237,954 - 122,461,669 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003130400   ⟸   XM_003130352
- UniProtKB: A0A4X1U4Y7 (UniProtKB/TrEMBL),   M3VH81 (UniProtKB/TrEMBL),   A0A8D1UCI7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000016473   ⟸   ENSSSCT00000016926
RefSeq Acc Id: ENSSSCP00000033241   ⟸   ENSSSCT00000059574
RefSeq Acc Id: ENSSSCP00000044268   ⟸   ENSSSCT00000045586
Protein Domains
EXS   SPX


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015537 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00035016687 UniProtKB/TrEMBL
  ENSSSCG00050062424 UniProtKB/TrEMBL
  ENSSSCG00055027477 UniProtKB/TrEMBL
  ENSSSCG00070014020 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016926 ENTREZGENE
  ENSSSCT00000016926.4 UniProtKB/TrEMBL
  ENSSSCT00000059574.2 UniProtKB/TrEMBL
  ENSSSCT00035021407.1 UniProtKB/TrEMBL
  ENSSSCT00035021412.1 UniProtKB/TrEMBL
  ENSSSCT00050085060.1 UniProtKB/TrEMBL
  ENSSSCT00050085067.1 UniProtKB/TrEMBL
  ENSSSCT00055054507.1 UniProtKB/TrEMBL
  ENSSSCT00070027482.1 UniProtKB/TrEMBL
  ENSSSCT00070027489.1 UniProtKB/TrEMBL
  ENSSSCT00070027501.1 UniProtKB/TrEMBL
  ENSSSCT00070027512.1 UniProtKB/TrEMBL
InterPro EXS_C UniProtKB/TrEMBL
  SPX_dom UniProtKB/TrEMBL
NCBI Gene XPR1 ENTREZGENE
PANTHER XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1 UniProtKB/TrEMBL
  XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED UniProtKB/TrEMBL
Pfam EXS UniProtKB/TrEMBL
  SPX UniProtKB/TrEMBL
PROSITE EXS UniProtKB/TrEMBL
  SPX UniProtKB/TrEMBL
UniProt A0A286ZNT1_PIG UniProtKB/TrEMBL
  A0A4X1U269_PIG UniProtKB/TrEMBL
  A0A4X1U4V7_PIG UniProtKB/TrEMBL
  A0A4X1U4Y7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U505_PIG UniProtKB/TrEMBL
  A0A8D1UCI7 ENTREZGENE, UniProtKB/TrEMBL
  F1S680_PIG UniProtKB/TrEMBL
  M3VH81 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:108625 ENTREZGENE