CPXM1 (carboxypeptidase X, M14 family member 1) - Rat Genome Database

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Gene: CPXM1 (carboxypeptidase X, M14 family member 1) Sus scrofa
Analyze
Symbol: CPXM1
Name: carboxypeptidase X, M14 family member 1
RGD ID: 13943931
Description: ENCODES a protein that exhibits carboxypeptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH Huntington's disease-like 1 (ortholog); pantothenate kinase-associated neurodegeneration (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable carboxypeptidase X1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,845,232 - 32,852,062 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,845,154 - 32,852,065 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,216,074 - 37,222,963 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
CPXM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,845,232 - 32,852,062 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,845,154 - 32,852,065 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,216,074 - 37,222,963 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CPXM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38202,794,074 - 2,800,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl202,794,074 - 2,800,627 (-)EnsemblGRCh38hg38GRCh38
GRCh37202,774,720 - 2,781,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,722,715 - 2,729,282 (-)NCBINCBI36Build 36hg18NCBI36
Build 34202,722,714 - 2,729,266NCBI
Celera202,839,233 - 2,845,810 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef202,724,251 - 2,730,828 (-)NCBIHuRef
CHM1_1202,774,764 - 2,781,341 (-)NCBICHM1_1
T2T-CHM13v2.0202,824,548 - 2,831,102 (-)NCBIT2T-CHM13v2.0
Cpxm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,232,695 - 130,239,549 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,232,695 - 130,239,494 (-)EnsemblGRCm39 Ensembl
GRCm382130,390,775 - 130,397,629 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,390,775 - 130,397,574 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,216,511 - 130,223,365 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,082,216 - 130,089,015 (-)NCBIMGSCv36mm8
Celera2131,615,457 - 131,622,311 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.22NCBI
Cpxm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,041,645 - 138,048,443 (-)NCBIGRCr8
mRatBN7.23117,588,532 - 117,595,330 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,588,532 - 117,595,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,486,474 - 121,493,272 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,081,972 - 130,088,770 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,742,598 - 127,749,396 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,913,886 - 122,920,684 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,913,886 - 122,920,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,414,247 - 129,421,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,000,980 - 118,007,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,906,682 - 117,913,606 (-)NCBI
Celera3116,402,737 - 116,409,535 (-)NCBICelera
Cytogenetic Map3q36NCBI
Cpxm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,756,889 - 13,763,120 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,756,752 - 13,763,764 (-)NCBIChiLan1.0ChiLan1.0
CPXM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,768,999 - 3,775,576 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,765,824 - 3,772,378 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,888,062 - 2,894,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,651,390 - 2,657,821 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,651,390 - 2,661,001 (-)Ensemblpanpan1.1panPan2
CPXM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,453,874 - 18,460,350 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,453,712 - 18,461,738 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,275,230 - 18,289,912 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,866,383 - 18,881,069 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,874,609 - 18,881,077 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,459,571 - 18,474,246 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,570,347 - 18,585,030 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,899,134 - 18,913,816 (+)NCBIUU_Cfam_GSD_1.0
Cpxm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,498,509 - 167,505,280 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,929,799 - 15,936,648 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648515,929,888 - 15,936,647 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPXM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1253,747,355 - 53,753,899 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl253,747,441 - 53,754,750 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666087162,104 - 169,145 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpxm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247413,930,547 - 3,936,572 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,930,417 - 3,936,649 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CPXM1
271 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 8 3 3 3 2 14 2 3 1
Below cutoff 2 1 2 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007843   ⟹   ENSSSCP00000007632
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1732,845,232 - 32,852,062 (+)Ensembl
RefSeq Acc Id: XM_003134333   ⟹   XP_003134381
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11732,845,238 - 32,852,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077785   ⟹   XP_020933444
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11732,845,154 - 32,852,065 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020933444   ⟸   XM_021077785
- Peptide Label: isoform X1
- UniProtKB: A0A8D1F6Z3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003134381   ⟸   XM_003134333
- Peptide Label: isoform X2
- UniProtKB: F1S8A0 (UniProtKB/TrEMBL),   A0A4X1SHD8 (UniProtKB/TrEMBL),   A0A480KGE1 (UniProtKB/TrEMBL),   A0A8D1F6Z3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000007632   ⟸   ENSSSCT00000007843
Protein Domains
F5/8 type C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00035047150 UniProtKB/TrEMBL
  ENSSSCG00040053118 UniProtKB/TrEMBL
  ENSSSCG00065068154 UniProtKB/TrEMBL
  ENSSSCG00070001034 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007843 ENTREZGENE
  ENSSSCT00000007843.5 UniProtKB/TrEMBL
  ENSSSCT00035062756.1 UniProtKB/TrEMBL
  ENSSSCT00035062760.1 UniProtKB/TrEMBL
  ENSSSCT00040071802.1 UniProtKB/TrEMBL
  ENSSSCT00040071867.1 UniProtKB/TrEMBL
  ENSSSCT00065093577.1 UniProtKB/TrEMBL
  ENSSSCT00070001960.1 UniProtKB/TrEMBL
Gene3D-CATH Carboxypeptidase-like, regulatory domain UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CarboxyPept-like_regulatory UniProtKB/TrEMBL
  FA58C UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
KEGG Report ssc:100512144 UniProtKB/TrEMBL
NCBI Gene CPXM1 ENTREZGENE
PANTHER CARBOXYPEPTIDASE X1-RELATED UniProtKB/TrEMBL
  PROTEASE M14 CARBOXYPEPTIDASE UniProtKB/TrEMBL
Pfam CarboxypepD_reg UniProtKB/TrEMBL
  F5_F8_type_C UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
  FA58C_1 UniProtKB/TrEMBL
  FA58C_3 UniProtKB/TrEMBL
SMART FA58C UniProtKB/TrEMBL
  Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A480KGE1 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SHD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZY35_PIG UniProtKB/TrEMBL
  A0A8D1A6G8_PIG UniProtKB/TrEMBL
  A0A8D1F429_PIG UniProtKB/TrEMBL
  A0A8D1F6Z3 ENTREZGENE, UniProtKB/TrEMBL
  F1S8A0 ENTREZGENE
UniProt Secondary F1S8A0 UniProtKB/TrEMBL
VGNC ID VGNC:95659 ENTREZGENE