CPXM1 (carboxypeptidase X, M14 family member 1) - Rat Genome Database

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Gene: CPXM1 (carboxypeptidase X, M14 family member 1) Pan paniscus
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Symbol: CPXM1
Name: carboxypeptidase X, M14 family member 1
RGD ID: 11839322
Description: ENCODES a protein that exhibits carboxypeptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH Huntington's disease-like 1 (ortholog); pantothenate kinase-associated neurodegeneration (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable carboxypeptidase X1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,768,999 - 3,775,576 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,765,824 - 3,772,378 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,888,062 - 2,894,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,651,390 - 2,657,821 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,651,390 - 2,661,001 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CPXM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,768,999 - 3,775,576 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1203,765,824 - 3,772,378 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,888,062 - 2,894,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1202,651,390 - 2,657,821 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,651,390 - 2,661,001 (-)Ensemblpanpan1.1panPan2
CPXM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38202,794,074 - 2,800,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl202,794,074 - 2,800,627 (-)EnsemblGRCh38hg38GRCh38
GRCh37202,774,720 - 2,781,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,722,715 - 2,729,282 (-)NCBINCBI36Build 36hg18NCBI36
Build 34202,722,714 - 2,729,266NCBI
Celera202,839,233 - 2,845,810 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef202,724,251 - 2,730,828 (-)NCBIHuRef
CHM1_1202,774,764 - 2,781,341 (-)NCBICHM1_1
T2T-CHM13v2.0202,824,548 - 2,831,102 (-)NCBIT2T-CHM13v2.0
Cpxm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,232,695 - 130,239,549 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,232,695 - 130,239,494 (-)EnsemblGRCm39 Ensembl
GRCm382130,390,775 - 130,397,629 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,390,775 - 130,397,574 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,216,511 - 130,223,365 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,082,216 - 130,089,015 (-)NCBIMGSCv36mm8
Celera2131,615,457 - 131,622,311 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.22NCBI
Cpxm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,041,645 - 138,048,443 (-)NCBIGRCr8
mRatBN7.23117,588,532 - 117,595,330 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,588,532 - 117,595,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,486,474 - 121,493,272 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,081,972 - 130,088,770 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,742,598 - 127,749,396 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,913,886 - 122,920,684 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,913,886 - 122,920,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,414,247 - 129,421,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,000,980 - 118,007,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,906,682 - 117,913,606 (-)NCBI
Celera3116,402,737 - 116,409,535 (-)NCBICelera
Cytogenetic Map3q36NCBI
Cpxm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,756,889 - 13,763,120 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,756,752 - 13,763,764 (-)NCBIChiLan1.0ChiLan1.0
CPXM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,453,874 - 18,460,350 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,453,712 - 18,461,738 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,275,230 - 18,289,912 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,866,383 - 18,881,069 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,874,609 - 18,881,077 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,459,571 - 18,474,246 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,570,347 - 18,585,030 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,899,134 - 18,913,816 (+)NCBIUU_Cfam_GSD_1.0
Cpxm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,498,509 - 167,505,280 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,929,799 - 15,936,648 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648515,929,888 - 15,936,647 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPXM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,845,232 - 32,852,062 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,845,154 - 32,852,065 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,216,074 - 37,222,963 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CPXM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1253,747,355 - 53,753,899 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl253,747,441 - 53,754,750 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666087162,104 - 169,145 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpxm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247413,930,547 - 3,936,572 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,930,417 - 3,936,649 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000049392   ⟹   ENSPPAP00000026558
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl202,651,390 - 2,657,827 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000049397   ⟹   ENSPPAP00000026563
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl202,651,506 - 2,661,001 (-)Ensembl
RefSeq Acc Id: XM_014342954   ⟹   XP_014198440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2213,768,999 - 3,775,576 (-)NCBI
NHGRI_mPanPan1203,765,824 - 3,772,377 (-)NCBI
Mhudiblu_PPA_v0202,888,062 - 2,894,613 (-)NCBI
PanPan1.1202,651,390 - 2,657,821 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034946975   ⟹   XP_034802866
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2213,768,999 - 3,775,556 (-)NCBI
NHGRI_mPanPan1203,765,824 - 3,772,378 (-)NCBI
Mhudiblu_PPA_v0202,888,062 - 2,894,614 (-)NCBI
Protein Sequences
Protein RefSeqs XP_014198440 (Get FASTA)   NCBI Sequence Viewer  
  XP_034802866 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000026558.1
  ENSPPAP00000026563.1
RefSeq Acc Id: XP_014198440   ⟸   XM_014342954
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BAD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034802866   ⟸   XM_034946975
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BAD5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000026563   ⟸   ENSPPAT00000049397
RefSeq Acc Id: ENSPPAP00000026558   ⟸   ENSPPAT00000049392
Protein Domains
F5/8 type C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036363 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049392.1 UniProtKB/TrEMBL
  ENSPPAT00000049397.1 UniProtKB/TrEMBL
Gene3D-CATH Carboxypeptidase-like, regulatory domain UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CarboxyPept-like_regulatory UniProtKB/TrEMBL
  FA58C UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene CPXM1 ENTREZGENE
PANTHER CARBOXYPEPTIDASE X1-RELATED UniProtKB/TrEMBL
  PROTEASE M14 CARBOXYPEPTIDASE UniProtKB/TrEMBL
Pfam CarboxypepD_reg UniProtKB/TrEMBL
  F5_F8_type_C UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
  FA58C_3 UniProtKB/TrEMBL
SMART FA58C UniProtKB/TrEMBL
  Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A2R9BAD5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BAD9_PANPA UniProtKB/TrEMBL