ADGRL3 (adhesion G protein-coupled receptor L3) - Rat Genome Database

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Gene: ADGRL3 (adhesion G protein-coupled receptor L3) Sus scrofa
Analyze
Symbol: ADGRL3
Name: adhesion G protein-coupled receptor L3
RGD ID: 13894643
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); INVOLVED IN locomotion involved in locomotory behavior (ortholog); maintenance of postsynaptic specialization structure (ortholog); neuron migration (ortholog); ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN axon (ortholog); cell-cell junction (ortholog); plasma membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: latrophilin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl860,630,117 - 60,792,899 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1859,988,280 - 60,800,177 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADGRL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl860,630,117 - 60,792,899 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1859,988,280 - 60,800,177 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ADGRL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38461,200,326 - 62,078,335 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl461,200,326 - 62,078,335 (+)EnsemblGRCh38hg38GRCh38
GRCh37462,066,044 - 62,944,053 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36462,045,434 - 62,620,763 (+)NCBINCBI36Build 36hg18NCBI36
Build 34462,191,604 - 62,766,933NCBI
Celera459,821,669 - 60,396,265 (+)NCBICelera
Cytogenetic Map4q13.1NCBI
HuRef458,271,407 - 58,846,164 (+)NCBIHuRef
CHM1_1462,398,708 - 62,974,117 (+)NCBICHM1_1
T2T-CHM13v2.0464,638,264 - 65,515,643 (+)NCBIT2T-CHM13v2.0
Adgrl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39581,167,600 - 81,980,556 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl581,167,985 - 81,972,980 (+)EnsemblGRCm39 Ensembl
GRCm38581,019,085 - 81,827,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl581,020,138 - 81,825,133 (+)EnsemblGRCm38mm10GRCm38
MGSCv37581,450,618 - 82,224,755 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36582,096,154 - 82,870,291 (+)NCBIMGSCv36mm8
Celera578,280,126 - 79,039,754 (+)NCBICelera
Cytogenetic Map5D- E1NCBI
cM Map542.62NCBI
Adgrl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81426,690,891 - 27,458,132 (-)NCBIGRCr8
mRatBN7.21426,336,320 - 27,104,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1426,368,277 - 27,105,860 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1426,715,441 - 27,465,812 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01428,027,851 - 28,778,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01426,509,623 - 27,260,039 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01428,362,176 - 29,226,085 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1428,393,394 - 28,967,980 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01428,183,727 - 29,040,121 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41428,385,112 - 28,854,677 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11428,385,120 - 28,854,677 (-)NCBI
Celera1425,731,451 - 26,185,004 (-)NCBICelera
Cytogenetic Map14p21NCBI
Adgrl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554479,943,598 - 10,709,008 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554479,912,679 - 10,708,743 (-)NCBIChiLan1.0ChiLan1.0
ADGRL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2367,717,238 - 68,578,490 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1467,937,970 - 68,799,235 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0461,876,694 - 62,742,354 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1468,315,996 - 69,183,881 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl468,323,404 - 69,003,093 (-)Ensemblpanpan1.1panPan2
ADGRL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11352,742,043 - 53,568,184 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1352,909,684 - 53,538,625 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1352,651,031 - 53,476,080 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01353,378,322 - 54,210,364 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1353,378,109 - 54,181,953 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11353,058,300 - 53,887,839 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01352,577,693 - 53,373,845 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01353,501,337 - 54,367,460 (+)NCBIUU_Cfam_GSD_1.0
Adgrl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528522,750,332 - 23,528,212 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365825,338,982 - 5,819,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365825,313,215 - 6,091,351 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.176,726,400 - 7,261,059 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660667,000,551 - 7,860,788 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247617,242,948 - 7,804,418 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247617,219,269 - 8,101,988 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ADGRL3
11554 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 23 2
Low 10 4 5 2 3 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000050951   ⟹   ENSSSCP00000035950
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl860,630,117 - 60,792,899 (+)Ensembl
RefSeq Acc Id: XM_021100590   ⟹   XP_020956249
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1859,988,280 - 60,800,177 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020956249 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000035950.2
  ENSSSCP00025015926.1
  ENSSSCP00045005439.1
  ENSSSCP00055020570.1
  ENSSSCP00070016791.1
Reference Protein Sequences
RefSeq Acc Id: XP_020956249   ⟸   XM_021100590
- UniProtKB: A0A4X1TNH8 (UniProtKB/TrEMBL),   A0A8D1QGK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000035950   ⟸   ENSSSCT00000050951
Protein Domains
G-protein coupled receptors family 2 profile   Olfactomedin-like   SUEL-type lectin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026129 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00025026497 UniProtKB/TrEMBL
  ENSSSCG00045004799 UniProtKB/TrEMBL
  ENSSSCG00055012279 UniProtKB/TrEMBL
  ENSSSCG00070009889 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000050951.2 UniProtKB/TrEMBL
  ENSSSCT00025037856.1 UniProtKB/TrEMBL
  ENSSSCT00045008050.1 UniProtKB/TrEMBL
  ENSSSCT00055025887.1 UniProtKB/TrEMBL
  ENSSSCT00070020196.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.610 UniProtKB/TrEMBL
  2.60.120.740 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_latrophilin UniProtKB/TrEMBL
  GPCR_2_latrophilin_rcpt_C UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  Lectin_gal-bd_dom UniProtKB/TrEMBL
  Lectin_gal-bd_sf UniProtKB/TrEMBL
  Olfac-like_dom UniProtKB/TrEMBL
NCBI Gene ADGRL3 ENTREZGENE
PANTHER ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PTHR12011:SF60 UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  Gal_Lectin UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  Latrophilin UniProtKB/TrEMBL
  OLF UniProtKB/TrEMBL
PRINTS GPCRSECRETIN UniProtKB/TrEMBL
  LATROPHILIN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  OLF UniProtKB/TrEMBL
  SUEL_LECTIN UniProtKB/TrEMBL
SMART GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  OLF UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A286ZWR2_PIG UniProtKB/TrEMBL
  A0A4X1TNH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1QGK5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:85137 ENTREZGENE