ACOX3 (acyl-CoA oxidase 3, pristanoyl) - Rat Genome Database

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Gene: ACOX3 (acyl-CoA oxidase 3, pristanoyl) Sus scrofa
Analyze
Symbol: ACOX3
Name: acyl-CoA oxidase 3, pristanoyl
RGD ID: 13860477
Description: ENCODES a protein that exhibits fatty acid binding (ortholog); flavin adenine dinucleotide binding (ortholog); pristanoyl-CoA oxidase activity (ortholog); INVOLVED IN fatty acid beta-oxidation using acyl-CoA oxidase (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); genetic disease (ortholog); FOUND IN peroxisome (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisomal acyl-coenzyme A oxidase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl82,716,918 - 2,770,801 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.182,716,913 - 2,756,221 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.284,391,443 - 4,418,723 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
peroxisome  (IBA,IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ACOX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl82,716,918 - 2,770,801 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.182,716,913 - 2,756,221 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.284,391,443 - 4,418,723 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACOX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3848,355,305 - 8,440,723 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl48,366,282 - 8,440,723 (-)EnsemblGRCh38hg38GRCh38
GRCh3748,368,009 - 8,442,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3648,418,909 - 8,493,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 3448,486,518 - 8,560,499NCBI
Celera48,261,321 - 8,335,759 (-)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef48,287,364 - 8,362,315 (-)NCBIHuRef
CHM1_148,366,366 - 8,440,788 (-)NCBICHM1_1
T2T-CHM13v2.048,337,453 - 8,420,469 (-)NCBIT2T-CHM13v2.0
Acox3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,740,293 - 35,772,397 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,740,384 - 35,772,696 (+)EnsemblGRCm39 Ensembl
GRCm38535,582,981 - 35,614,208 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl535,583,040 - 35,615,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,925,709 - 35,956,450 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,899,921 - 35,930,662 (+)NCBIMGSCv36mm8
Celera533,056,108 - 33,087,085 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map518.32NCBI
Acox3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81479,358,604 - 79,405,160 (-)NCBIGRCr8
mRatBN7.21475,133,986 - 75,176,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,094,676 - 75,176,205 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1479,575,514 - 79,629,707 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01480,816,379 - 80,870,575 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01477,261,371 - 77,315,558 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01480,313,202 - 80,358,115 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,314,431 - 80,355,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01479,942,668 - 79,982,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41480,769,000 - 80,809,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11480,771,390 - 80,812,200 (-)NCBI
Celera1474,065,866 - 74,104,532 (-)NCBICelera
Cytogenetic Map14q21NCBI
Acox3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555142,656,144 - 2,685,896 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555142,653,502 - 2,690,452 (+)NCBIChiLan1.0ChiLan1.0
ACOX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v238,642,020 - 8,727,303 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan148,569,231 - 8,654,531 (-)NCBINHGRI_mPanPan1
PanPan1.148,432,788 - 8,506,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl48,432,788 - 8,494,157 (-)Ensemblpanpan1.1panPan2
ACOX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1360,154,012 - 60,205,696 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl360,153,775 - 60,203,554 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha362,804,141 - 62,856,135 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0360,631,684 - 60,683,139 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl360,628,819 - 60,680,866 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1360,123,908 - 60,162,124 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0360,327,224 - 60,379,691 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0360,685,106 - 60,736,638 (-)NCBIUU_Cfam_GSD_1.0
Acox3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528565,992,882 - 66,029,673 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647719,694,555 - 19,731,386 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647719,696,274 - 19,731,338 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACOX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12744,313,297 - 44,366,702 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666051635,738 - 689,992 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acox3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475523,995,089 - 24,024,083 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475523,995,256 - 24,026,581 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ACOX3
1831 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 9 4 3 4 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000009544   ⟹   ENSSSCP00000009299
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,927 - 2,756,217 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000046718   ⟹   ENSSSCP00000033875
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,927 - 2,770,801 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000063782   ⟹   ENSSSCP00000054952
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,944 - 2,756,216 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000069702   ⟹   ENSSSCP00000065412
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,944 - 2,753,224 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000071848   ⟹   ENSSSCP00000070659
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,947 - 2,754,151 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000073205   ⟹   ENSSSCP00000069706
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,918 - 2,756,086 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000086938   ⟹   ENSSSCP00000062930
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,927 - 2,756,217 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000089545   ⟹   ENSSSCP00000071344
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl82,716,924 - 2,775,333 (+)Ensembl
RefSeq Acc Id: XM_021100951   ⟹   XP_020956610
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,716,913 - 2,756,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021100952   ⟹   XP_020956611
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,717,203 - 2,756,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021100953   ⟹   XP_020956612
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,716,913 - 2,756,221 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346545
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,716,913 - 2,756,221 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346546
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,716,913 - 2,755,527 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346547
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,716,913 - 2,756,221 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346548
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.182,716,913 - 2,756,221 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020956610   ⟸   XM_021100951
- Peptide Label: isoform X1
- UniProtKB: A0A5G2QLH9 (UniProtKB/TrEMBL),   A0A480VSI5 (UniProtKB/TrEMBL),   A0A8D1PCC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020956612   ⟸   XM_021100953
- Peptide Label: isoform X2
- UniProtKB: A0A287BF51 (UniProtKB/TrEMBL),   A0A480VSI5 (UniProtKB/TrEMBL),   A0A8D1PCC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020956611   ⟸   XM_021100952
- Peptide Label: isoform X1
- UniProtKB: A0A5G2QLH9 (UniProtKB/TrEMBL),   A0A480VSI5 (UniProtKB/TrEMBL),   A0A8D1PCC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000009299   ⟸   ENSSSCT00000009544
RefSeq Acc Id: ENSSSCP00000071344   ⟸   ENSSSCT00000089545
RefSeq Acc Id: ENSSSCP00000065412   ⟸   ENSSSCT00000069702
RefSeq Acc Id: ENSSSCP00000033875   ⟸   ENSSSCT00000046718
RefSeq Acc Id: ENSSSCP00000070659   ⟸   ENSSSCT00000071848
RefSeq Acc Id: ENSSSCP00000054952   ⟸   ENSSSCT00000063782
RefSeq Acc Id: ENSSSCP00000069706   ⟸   ENSSSCT00000073205
RefSeq Acc Id: ENSSSCP00000062930   ⟸   ENSSSCT00000086938
Protein Domains
Acyl-CoA oxidase C-terminal   Acyl-CoA oxidase/dehydrogenase middle


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008724 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00055001752 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009544.4 UniProtKB/TrEMBL
  ENSSSCT00000046718.3 UniProtKB/TrEMBL
  ENSSSCT00000063782 ENTREZGENE
  ENSSSCT00000063782.2 UniProtKB/TrEMBL
  ENSSSCT00000069702 ENTREZGENE
  ENSSSCT00000069702.2 UniProtKB/TrEMBL
  ENSSSCT00000071848.1 UniProtKB/TrEMBL
  ENSSSCT00000073205.1 UniProtKB/TrEMBL
  ENSSSCT00000086938 ENTREZGENE
  ENSSSCT00000086938.2 UniProtKB/TrEMBL
  ENSSSCT00055003273.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.110.10 UniProtKB/TrEMBL
  Butyryl-CoA Dehydrogenase, subunit A, domain 3 UniProtKB/TrEMBL
InterPro ACO UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_cen-dom UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_mid-dom_sf UniProtKB/TrEMBL
  Acyl-CoA_oxidase UniProtKB/TrEMBL
  Acyl-CoA_oxidase_C UniProtKB/TrEMBL
  AcylCo_DH-like_C UniProtKB/TrEMBL
  AcylCoA_DH/oxidase_NM_dom UniProtKB/TrEMBL
NCBI Gene ACOX3 ENTREZGENE
PANTHER PEROXISOMAL ACYL-COENZYME A OXIDASE 3 UniProtKB/TrEMBL
  PTHR10909 UniProtKB/TrEMBL
Pfam ACOX UniProtKB/TrEMBL
  Acyl-CoA_dh_M UniProtKB/TrEMBL
PIRSF Acyl-CoA_oxidase UniProtKB/TrEMBL
Superfamily-SCOP SSF47203 UniProtKB/TrEMBL
  SSF56645 UniProtKB/TrEMBL
UniProt A0A286ZQX8_PIG UniProtKB/TrEMBL
  A0A287BF51 ENTREZGENE, UniProtKB/TrEMBL
  A0A480VSI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QLH9 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R4C5_PIG UniProtKB/TrEMBL
  A0A5G2R6F3_PIG UniProtKB/TrEMBL
  A0A5G2R961_PIG UniProtKB/TrEMBL
  A0A8D1PCC7 ENTREZGENE, UniProtKB/TrEMBL
  F1S7X9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85022 ENTREZGENE