SLC35G1 (solute carrier family 35 member G1) - Rat Genome Database

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Gene: SLC35G1 (solute carrier family 35 member G1) Homo sapiens
Analyze
Symbol: SLC35G1
Name: solute carrier family 35 member G1
RGD ID: 1354059
HGNC Page HGNC:26607
Description: Involved in calcium ion export across plasma membrane and regulation of cytosolic calcium ion concentration. Located in endoplasmic reticulum membrane and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C10orf60; FLJ33990; partner of STIM1; POST; solute carrier family 35, member G1; TMEM20; transmembrane protein 20
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381093,893,978 - 93,909,830 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1093,893,973 - 93,956,062 (+)EnsemblGRCh38hg38GRCh38
GRCh371095,653,735 - 95,669,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361095,643,720 - 95,652,480 (+)NCBINCBI36Build 36hg18NCBI36
Build 341095,643,719 - 95,652,480NCBI
Celera1089,393,872 - 89,402,633 (+)NCBICelera
Cytogenetic Map10q23.33NCBI
HuRef1089,280,458 - 89,289,217 (+)NCBIHuRef
CHM1_11095,935,595 - 95,944,354 (+)NCBICHM1_1
T2T-CHM13v2.01094,773,053 - 94,788,891 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:14702039   PMID:15164054   PMID:15489334   PMID:16344560   PMID:19322201   PMID:21569384   PMID:21873635   PMID:22084111   PMID:25775029   PMID:27028160   PMID:29666234  
PMID:31067453   PMID:31753913   PMID:31980649   PMID:32296183   PMID:32513696   PMID:33961781   PMID:37393044  


Genomics

Comparative Map Data
SLC35G1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381093,893,978 - 93,909,830 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1093,893,973 - 93,956,062 (+)EnsemblGRCh38hg38GRCh38
GRCh371095,653,735 - 95,669,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361095,643,720 - 95,652,480 (+)NCBINCBI36Build 36hg18NCBI36
Build 341095,643,719 - 95,652,480NCBI
Celera1089,393,872 - 89,402,633 (+)NCBICelera
Cytogenetic Map10q23.33NCBI
HuRef1089,280,458 - 89,289,217 (+)NCBIHuRef
CHM1_11095,935,595 - 95,944,354 (+)NCBICHM1_1
T2T-CHM13v2.01094,773,053 - 94,788,891 (+)NCBIT2T-CHM13v2.0
Slc35g1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,384,428 - 38,394,055 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1938,384,428 - 38,394,058 (+)EnsemblGRCm39 Ensembl
GRCm381938,395,980 - 38,405,607 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1938,395,980 - 38,405,610 (+)EnsemblGRCm38mm10GRCm38
MGSCv371938,470,470 - 38,480,097 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361938,461,124 - 38,470,751 (+)NCBIMGSCv36mm8
Celera1939,188,137 - 39,193,307 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1933.03NCBI
Slc35g1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81245,576,011 - 245,584,533 (+)NCBIGRCr8
mRatBN7.21236,163,593 - 236,172,115 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,163,175 - 236,170,262 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1244,586,084 - 244,592,520 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01251,480,841 - 251,487,275 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01244,319,095 - 244,325,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01257,076,221 - 257,082,655 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1257,076,221 - 257,082,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01264,556,961 - 264,563,395 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,713,535 - 242,719,969 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1233,256,993 - 233,263,274 (+)NCBICelera
Cytogenetic Map1q53NCBI
Slc35g1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955507423,351 - 428,051 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955507423,354 - 428,051 (+)NCBIChiLan1.0ChiLan1.0
SLC35G1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28105,931,348 - 105,986,626 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110105,936,663 - 105,991,850 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01090,641,079 - 90,696,621 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11094,152,493 - 94,162,201 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1094,152,493 - 94,162,201 (+)Ensemblpanpan1.1panPan2
SLC35G1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1288,080,614 - 8,091,347 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha288,256,548 - 8,267,456 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0288,340,692 - 8,351,613 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1288,060,062 - 8,070,433 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0288,089,729 - 8,100,111 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0288,259,479 - 8,270,398 (+)NCBIUU_Cfam_GSD_1.0
Slc35g1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721339,539,163 - 39,549,248 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366011,170,777 - 1,181,960 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366011,171,542 - 1,181,699 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC35G1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14105,335,160 - 105,345,274 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114105,335,063 - 105,345,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214115,066,444 - 115,076,760 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC35G1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1987,127,367 - 87,137,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604847,909,760 - 47,926,068 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc35g1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247375,177,500 - 5,185,834 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247375,177,430 - 5,188,248 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC35G1
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q23.33-24.2(chr10:92626680-97755102)x1 copy number loss See cases [RCV000052564] Chr10:92626680..97755102 [GRCh38]
Chr10:94386437..99514859 [GRCh37]
Chr10:94376417..99504849 [NCBI36]
Chr10:10q23.33-24.2		 pathogenic
GRCh38/hg38 10q23.33-24.32(chr10:93181201-101356779)x1 copy number loss See cases [RCV000052565] Chr10:93181201..101356779 [GRCh38]
Chr10:94940958..103116536 [GRCh37]
Chr10:94930948..103106526 [NCBI36]
Chr10:10q23.33-24.32		 pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3		 pathogenic
NM_001134658.3(SLC35G1):c.427G>A (p.Ala143Thr) single nucleotide variant Malignant tumor of prostate [RCV000149357] Chr10:93900819 [GRCh38]
Chr10:95660576 [GRCh37]
Chr10:10q23.33		 uncertain significance
GRCh38/hg38 10q23.33-24.1(chr10:92643919-95471137)x1 copy number loss See cases [RCV000137919] Chr10:92643919..95471137 [GRCh38]
Chr10:94403676..97230894 [GRCh37]
Chr10:94393656..97220884 [NCBI36]
Chr10:10q23.33-24.1		 pathogenic
GRCh37/hg19 10q23.31-24.1(chr10:92667881-98970384)x1 copy number loss See cases [RCV000447362] Chr10:92667881..98970384 [GRCh37]
Chr10:10q23.31-24.1		 pathogenic
GRCh37/hg19 10q23.1-25.1(chr10:85557432-105804295)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000431909] Chr10:85557432..105804295 [GRCh37]
Chr10:10q23.1-25.1		 pathogenic|drug response
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q23.32-23.33(chr10:93186527-95820286)x1 copy number loss See cases [RCV000511278] Chr10:93186527..95820286 [GRCh37]
Chr10:10q23.32-23.33		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
GRCh37/hg19 10q23.32-24.2(chr10:93908171-101809723)x1 copy number loss See cases [RCV000512315] Chr10:93908171..101809723 [GRCh37]
Chr10:10q23.32-24.2		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q23.33-24.1(chr10:94393383-97219175) copy number loss not provided [RCV000767566] Chr10:94393383..97219175 [GRCh37]
Chr10:10q23.33-24.1		 likely pathogenic
NM_001134658.3(SLC35G1):c.209T>C (p.Leu70Pro) single nucleotide variant not specified [RCV004317216] Chr10:93898601 [GRCh38]
Chr10:95658358 [GRCh37]
Chr10:10q23.33		 uncertain significance
GRCh37/hg19 10q23.31-23.33(chr10:89823147-96056941)x1 copy number loss not provided [RCV002472645] Chr10:89823147..96056941 [GRCh37]
Chr10:10q23.31-23.33		 pathogenic
GRCh37/hg19 10q23.31-24.1(chr10:92667881-98970384) copy number loss not specified [RCV002052882] Chr10:92667881..98970384 [GRCh37]
Chr10:10q23.31-24.1		 pathogenic
NM_001134658.3(SLC35G1):c.188A>G (p.Lys63Arg) single nucleotide variant not specified [RCV004114535] Chr10:93898580 [GRCh38]
Chr10:95658337 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.1078T>C (p.Trp360Arg) single nucleotide variant not specified [RCV004116612] Chr10:93901470 [GRCh38]
Chr10:95661227 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.373G>A (p.Gly125Ser) single nucleotide variant not specified [RCV004113038] Chr10:93900765 [GRCh38]
Chr10:95660522 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.152C>T (p.Ser51Leu) single nucleotide variant not specified [RCV004091865] Chr10:93894185 [GRCh38]
Chr10:95653942 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.44C>T (p.Pro15Leu) single nucleotide variant not specified [RCV004096706] Chr10:93894077 [GRCh38]
Chr10:95653834 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.55C>A (p.Leu19Ile) single nucleotide variant not specified [RCV004074439] Chr10:93894088 [GRCh38]
Chr10:95653845 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.973G>C (p.Ala325Pro) single nucleotide variant not specified [RCV004170032] Chr10:93901365 [GRCh38]
Chr10:95661122 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.77G>T (p.Gly26Val) single nucleotide variant not specified [RCV004231188] Chr10:93894110 [GRCh38]
Chr10:95653867 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.265G>C (p.Val89Leu) single nucleotide variant not specified [RCV004176718] Chr10:93898657 [GRCh38]
Chr10:95658414 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.132G>T (p.Arg44Ser) single nucleotide variant not specified [RCV004182463] Chr10:93894165 [GRCh38]
Chr10:95653922 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.790G>T (p.Val264Phe) single nucleotide variant not specified [RCV004089806] Chr10:93901182 [GRCh38]
Chr10:95660939 [GRCh37]
Chr10:10q23.33		 likely benign
NM_001134658.3(SLC35G1):c.875G>T (p.Gly292Val) single nucleotide variant not specified [RCV004166402] Chr10:93901267 [GRCh38]
Chr10:95661024 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.443A>G (p.Tyr148Cys) single nucleotide variant not specified [RCV004142328] Chr10:93900835 [GRCh38]
Chr10:95660592 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.410G>A (p.Gly137Glu) single nucleotide variant not specified [RCV004326828] Chr10:93900802 [GRCh38]
Chr10:95660559 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.1072C>A (p.Arg358Ser) single nucleotide variant not specified [RCV004276059] Chr10:93901464 [GRCh38]
Chr10:95661221 [GRCh37]
Chr10:10q23.33		 uncertain significance
GRCh37/hg19 10q23.32-24.1(chr10:93281410-97596360)x1 copy number loss See cases [RCV003159569] Chr10:93281410..97596360 [GRCh37]
Chr10:10q23.32-24.1		 pathogenic
NM_001134658.3(SLC35G1):c.443A>T (p.Tyr148Phe) single nucleotide variant not specified [RCV004259589] Chr10:93900835 [GRCh38]
Chr10:95660592 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.625T>C (p.Ser209Pro) single nucleotide variant not specified [RCV004248289] Chr10:93901017 [GRCh38]
Chr10:95660774 [GRCh37]
Chr10:10q23.33		 uncertain significance
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
NM_001134658.3(SLC35G1):c.872T>C (p.Ile291Thr) single nucleotide variant not specified [RCV004344418] Chr10:93901264 [GRCh38]
Chr10:95661021 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.109G>C (p.Ala37Pro) single nucleotide variant not specified [RCV004358242] Chr10:93894142 [GRCh38]
Chr10:95653899 [GRCh37]
Chr10:10q23.33		 uncertain significance
GRCh37/hg19 10q11.21-24.2(chr10:42709645-100834951)x3 copy number gain not provided [RCV003484798] Chr10:42709645..100834951 [GRCh37]
Chr10:10q11.21-24.2		 pathogenic
GRCh37/hg19 10q23.32-23.33(chr10:93788061-96452666)x3 copy number gain not provided [RCV003484809] Chr10:93788061..96452666 [GRCh37]
Chr10:10q23.32-23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.864C>G (p.Leu288=) single nucleotide variant not provided [RCV003422748] Chr10:93901256 [GRCh38]
Chr10:95661013 [GRCh37]
Chr10:10q23.33		 likely benign
GRCh37/hg19 10q23.33-24.2(chr10:94283369-101820913)x1 copy number loss not specified [RCV003986912] Chr10:94283369..101820913 [GRCh37]
Chr10:10q23.33-24.2		 pathogenic
GRCh37/hg19 10q23.31-24.2(chr10:90796994-100067505)x1 copy number loss not specified [RCV003986861] Chr10:90796994..100067505 [GRCh37]
Chr10:10q23.31-24.2		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:95078198-135427143)x3 copy number gain not specified [RCV003986893] Chr10:95078198..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
NM_001134658.3(SLC35G1):c.541A>G (p.Lys181Glu) single nucleotide variant not specified [RCV004459335] Chr10:93900933 [GRCh38]
Chr10:95660690 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.635C>T (p.Ser212Leu) single nucleotide variant not specified [RCV004459337] Chr10:93901027 [GRCh38]
Chr10:95660784 [GRCh37]
Chr10:10q23.33		 likely benign
NM_001134658.3(SLC35G1):c.449C>T (p.Ala150Val) single nucleotide variant not specified [RCV004459334] Chr10:93900841 [GRCh38]
Chr10:95660598 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.351A>G (p.Ile117Met) single nucleotide variant not specified [RCV004459333] Chr10:93898743 [GRCh38]
Chr10:95658500 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.605G>C (p.Arg202Thr) single nucleotide variant not specified [RCV004459336] Chr10:93900997 [GRCh38]
Chr10:95660754 [GRCh37]
Chr10:10q23.33		 uncertain significance
NM_001134658.3(SLC35G1):c.85G>A (p.Glu29Lys) single nucleotide variant not specified [RCV004459338] Chr10:93894118 [GRCh38]
Chr10:95653875 [GRCh37]
Chr10:10q23.33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2880
Count of miRNA genes:930
Interacting mature miRNAs:1103
Transcripts:ENST00000371408, ENST00000427197, ENST00000483386, ENST00000494992, ENST00000603665, ENST00000605679
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-14114  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371095,669,462 - 95,669,564UniSTSGRCh37
Build 361095,659,452 - 95,659,554RGDNCBI36
Celera1089,409,608 - 89,409,710RGD
Cytogenetic Map10q23.33UniSTS
HuRef1089,296,191 - 89,296,293UniSTS
GeneMap99-GB4 RH Map10441.05UniSTS
Whitehead-RH Map10530.6UniSTS
RH104340  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371095,661,221 - 95,661,342UniSTSGRCh37
Build 361095,651,211 - 95,651,332RGDNCBI36
Celera1089,401,363 - 89,401,484RGD
Cytogenetic Map10q23.33UniSTS
HuRef1089,287,949 - 89,288,070UniSTS
GeneMap99-GB4 RH Map10445.29UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 91 17 11 29 11 25 11 29 9 49 55 1 1
Low 2348 1904 1687 602 1140 444 4119 1794 3389 364 1402 1548 172 1200 2580 6 2
Below cutoff 1086 22 11 756 10 212 391 316 44 9 5 1 4 208

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_051626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001134658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_144335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_144336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_144337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK091309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL138923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC041432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC104814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM677569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU608007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA644843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  R56424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000371408   ⟹   ENSP00000360462
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1093,893,973 - 93,903,824 (+)Ensembl
RefSeq Acc Id: ENST00000427197   ⟹   ENSP00000400932
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1093,893,978 - 93,903,824 (+)Ensembl
RefSeq Acc Id: ENST00000483386   ⟹   ENSP00000473766
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1093,893,991 - 93,909,830 (+)Ensembl
RefSeq Acc Id: ENST00000494992   ⟹   ENSP00000474294
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1093,894,002 - 93,956,062 (+)Ensembl
RefSeq Acc Id: ENST00000603665   ⟹   ENSP00000473862
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1093,894,022 - 93,909,825 (+)Ensembl
RefSeq Acc Id: ENST00000605679   ⟹   ENSP00000474890
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1093,894,001 - 93,954,256 (+)Ensembl
RefSeq Acc Id: NM_001134658   ⟹   NP_001128130
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,903,824 (+)NCBI
GRCh371095,653,730 - 95,663,581 (+)NCBI
Celera1089,393,872 - 89,402,633 (+)RGD
HuRef1089,280,458 - 89,289,217 (+)ENTREZGENE
CHM1_11095,935,595 - 95,944,354 (+)NCBI
T2T-CHM13v2.01094,773,053 - 94,782,897 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001345993   ⟹   NP_001332922
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,903,824 (+)NCBI
T2T-CHM13v2.01094,773,053 - 94,782,897 (+)NCBI
Sequence:
RefSeq Acc Id: NM_153226   ⟹   NP_694958
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,903,824 (+)NCBI
GRCh371095,653,730 - 95,663,581 (+)NCBI
Build 361095,643,720 - 95,652,480 (+)NCBI Archive
Celera1089,393,872 - 89,402,633 (+)RGD
HuRef1089,280,458 - 89,289,217 (+)ENTREZGENE
CHM1_11095,935,595 - 95,944,354 (+)NCBI
T2T-CHM13v2.01094,773,053 - 94,782,897 (+)NCBI
Sequence:
RefSeq Acc Id: NR_144335
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,909,830 (+)NCBI
T2T-CHM13v2.01094,773,053 - 94,788,891 (+)NCBI
Sequence:
RefSeq Acc Id: NR_144336
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,909,830 (+)NCBI
T2T-CHM13v2.01094,773,053 - 94,788,891 (+)NCBI
Sequence:
RefSeq Acc Id: NR_144337
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,909,830 (+)NCBI
T2T-CHM13v2.01094,773,053 - 94,788,891 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_694958   ⟸   NM_153226
- Peptide Label: isoform 2
- UniProtKB: B7ZKP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001128130   ⟸   NM_001134658
- Peptide Label: isoform 1
- UniProtKB: Q86YG5 (UniProtKB/Swiss-Prot),   Q8NBA5 (UniProtKB/Swiss-Prot),   Q2M3R5 (UniProtKB/Swiss-Prot),   B7ZKP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001332922   ⟸   NM_001345993
- Peptide Label: isoform 3
- UniProtKB: B7ZKP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000360462   ⟸   ENST00000371408
RefSeq Acc Id: ENSP00000400932   ⟸   ENST00000427197
RefSeq Acc Id: ENSP00000474294   ⟸   ENST00000494992
RefSeq Acc Id: ENSP00000473766   ⟸   ENST00000483386
RefSeq Acc Id: ENSP00000473862   ⟸   ENST00000603665
RefSeq Acc Id: ENSP00000474890   ⟸   ENST00000605679
Protein Domains
EamA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2M3R5-F1-model_v2 AlphaFold Q2M3R5 1-365 view protein structure

Promoters
RGD ID:7218211
Promoter ID:EPDNEW_H14851
Type:initiation region
Name:SLC35G1_1
Description:solute carrier family 35 member G1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381093,893,978 - 93,894,038EPDNEW
RGD ID:6788316
Promoter ID:HG_KWN:10612
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001134658,   OTTHUMT00000049451,   OTTHUMT00000049452,   OTTHUMT00000049453,   UC001KJH.2,   UC001KJI.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361095,643,516 - 95,644,016 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26607 AgrOrtholog
COSMIC SLC35G1 COSMIC
Ensembl Genes ENSG00000176273 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000371408 ENTREZGENE
  ENST00000371408.7 UniProtKB/Swiss-Prot
  ENST00000427197 ENTREZGENE
  ENST00000427197.2 UniProtKB/Swiss-Prot
  ENST00000483386 ENTREZGENE
  ENST00000483386.5 UniProtKB/TrEMBL
  ENST00000494992.5 UniProtKB/TrEMBL
  ENST00000603665 ENTREZGENE
  ENST00000603665.1 UniProtKB/TrEMBL
  ENST00000605679.5 UniProtKB/TrEMBL
GTEx ENSG00000176273 GTEx
HGNC ID HGNC:26607 ENTREZGENE
Human Proteome Map SLC35G1 Human Proteome Map
InterPro EamA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:159371 UniProtKB/Swiss-Prot
NCBI Gene 159371 ENTREZGENE
OMIM 617167 OMIM
PANTHER ACYL-MALONYL CONDENSING ENZYME-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 35 MEMBER G1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EamA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134933626 PharmGKB
Superfamily-SCOP Multidrug resistance efflux transporter EmrE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B7ZKP0 ENTREZGENE, UniProtKB/TrEMBL
  B7ZKP1 ENTREZGENE, UniProtKB/TrEMBL
  D3DR41_HUMAN UniProtKB/TrEMBL
  Q2M3R5 ENTREZGENE
  Q86YG5 ENTREZGENE
  Q8NBA5 ENTREZGENE
  S35G1_HUMAN UniProtKB/Swiss-Prot
  S4R2Y7_HUMAN UniProtKB/TrEMBL
UniProt Secondary Q86YG5 UniProtKB/Swiss-Prot
  Q8NBA5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-08 SLC35G1  solute carrier family 35 member G1    solute carrier family 35, member G1  Symbol and/or name change 5135510 APPROVED
2011-09-01 SLC35G1  solute carrier family 35, member G1  TMEM20  transmembrane protein 20  Symbol and/or name change 5135510 APPROVED