EIF4E3 (eukaryotic translation initiation factor 4E family member 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: EIF4E3 (eukaryotic translation initiation factor 4E family member 3) Homo sapiens
Analyze
Symbol: EIF4E3
Name: eukaryotic translation initiation factor 4E family member 3
RGD ID: 1348241
HGNC Page HGNC:31837
Description: Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 4F complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eIF-4E type 3; eIF-4E3; eIF4E type 3; eIF4E-3; eukaryotic translation initiation factor 4E member 3; eukaryotic translation initiation factor 4E type 3; MGC39820; MGC86971
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38371,659,363 - 71,754,773 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl371,675,414 - 71,754,773 (-)EnsemblGRCh38hg38GRCh38
GRCh37371,724,565 - 71,803,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36371,814,568 - 71,885,465 (-)NCBINCBI36Build 36hg18NCBI36
Build 34371,814,567 - 71,885,465NCBI
Celera371,659,031 - 71,734,517 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef371,730,725 - 71,780,383 (-)NCBIHuRef
CHM1_1371,680,022 - 71,755,333 (-)NCBICHM1_1
T2T-CHM13v2.0371,698,509 - 71,794,043 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients. Zhou Z, etal., Cell Host Microbe. 2020 Jun 10;27(6):883-890.e2. doi: 10.1016/j.chom.2020.04.017. Epub 2020 May 4.
Additional References at PubMed
PMID:12477932   PMID:15153109   PMID:16344560   PMID:19322201   PMID:20434207   PMID:21873635   PMID:23333304   PMID:23431134   PMID:23587918   PMID:25403230   PMID:26186194   PMID:26354767  
PMID:27578149   PMID:28514442   PMID:28942592   PMID:32296183   PMID:33893802   PMID:33961781   PMID:35156780   PMID:37067401  


Genomics

Comparative Map Data
EIF4E3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38371,659,363 - 71,754,773 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl371,675,414 - 71,754,773 (-)EnsemblGRCh38hg38GRCh38
GRCh37371,724,565 - 71,803,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36371,814,568 - 71,885,465 (-)NCBINCBI36Build 36hg18NCBI36
Build 34371,814,567 - 71,885,465NCBI
Celera371,659,031 - 71,734,517 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef371,730,725 - 71,780,383 (-)NCBIHuRef
CHM1_1371,680,022 - 71,755,333 (-)NCBICHM1_1
T2T-CHM13v2.0371,698,509 - 71,794,043 (-)NCBIT2T-CHM13v2.0
Eif4e3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39699,599,008 - 99,669,834 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl699,602,096 - 99,643,732 (-)EnsemblGRCm39 Ensembl
GRCm38699,621,879 - 99,692,873 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl699,625,135 - 99,666,771 (-)EnsemblGRCm38mm10GRCm38
MGSCv37699,575,131 - 99,616,765 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36699,590,600 - 99,632,234 (-)NCBIMGSCv36mm8
Celera6101,489,380 - 101,530,927 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map645.98NCBI
Eif4e3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84133,709,802 - 133,858,398 (-)NCBIGRCr8
mRatBN7.24132,258,502 - 132,301,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4132,258,502 - 132,301,808 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4137,675,414 - 137,719,126 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04133,456,200 - 133,499,910 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04132,074,463 - 132,118,181 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04132,068,581 - 132,111,092 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4132,068,598 - 132,111,079 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04196,560,131 - 196,602,330 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44134,470,883 - 134,514,084 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4121,118,126 - 121,161,071 (-)NCBICelera
Cytogenetic Map4q34NCBI
Eif4e3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542116,354,282 - 16,419,304 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542116,354,282 - 16,520,422 (+)NCBIChiLan1.0ChiLan1.0
EIF4E3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2271,641,978 - 71,684,653 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1371,646,766 - 71,689,440 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0371,617,040 - 71,694,523 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1372,975,451 - 73,049,525 (-)NCBIpanpan1.1PanPan1.1panPan2
EIF4E3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12020,299,757 - 20,349,561 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2020,327,676 - 20,438,998 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2020,277,217 - 20,327,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02020,334,599 - 20,384,614 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2020,308,954 - 21,026,250 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12020,024,761 - 20,065,042 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02020,373,429 - 20,413,727 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02020,436,369 - 20,486,225 (+)NCBIUU_Cfam_GSD_1.0
Eif4e3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049423,229,927 - 3,286,977 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366033,227,138 - 3,245,939 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366033,228,091 - 3,285,311 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF4E3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1353,083,645 - 53,124,240 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11353,080,200 - 53,152,335 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21358,771,253 - 58,816,633 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF4E3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12232,635,144 - 32,708,932 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041134,070,942 - 134,144,820 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif4e3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247736,219,199 - 6,267,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247736,047,763 - 6,264,641 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EIF4E3
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p14.1-12.3(chr3:64761248-78410098)x1 copy number loss See cases [RCV000051512] Chr3:64761248..78410098 [GRCh38]
Chr3:64746924..78459248 [GRCh37]
Chr3:64721964..78541938 [NCBI36]
Chr3:3p14.1-12.3		 pathogenic
GRCh38/hg38 3p13-12.3(chr3:70296167-74865078)x1 copy number loss See cases [RCV000051513] Chr3:70296167..74865078 [GRCh38]
Chr3:70345318..74914229 [GRCh37]
Chr3:70428008..74996919 [NCBI36]
Chr3:3p13-12.3		 pathogenic
GRCh38/hg38 3p14.1-13(chr3:67391006-73414001)x1 copy number loss See cases [RCV000133821] Chr3:67391006..73414001 [GRCh38]
Chr3:67441430..73463152 [GRCh37]
Chr3:67524120..73545842 [NCBI36]
Chr3:3p14.1-13		 pathogenic
GRCh38/hg38 3p13(chr3:70943620-71861889)x1 copy number loss See cases [RCV000137697] Chr3:70943620..71861889 [GRCh38]
Chr3:70992771..71911040 [GRCh37]
Chr3:71075461..71993730 [NCBI36]
Chr3:3p13		 pathogenic
GRCh38/hg38 3p14.1-12.3(chr3:68328980-76764319)x3 copy number gain See cases [RCV000140215] Chr3:68328980..76764319 [GRCh38]
Chr3:68378130..76813470 [GRCh37]
Chr3:68460820..76896160 [NCBI36]
Chr3:3p14.1-12.3		 likely pathogenic|uncertain significance
GRCh38/hg38 3p14.3-11.1(chr3:57140424-90259960)x1 copy number loss See cases [RCV000139626] Chr3:57140424..90259960 [GRCh38]
Chr3:57174452..90309110 [GRCh37]
Chr3:57149492..90391800 [NCBI36]
Chr3:3p14.3-11.1		 pathogenic
GRCh38/hg38 3p13-12.3(chr3:71317346-74324671)x1 copy number loss See cases [RCV000142649] Chr3:71317346..74324671 [GRCh38]
Chr3:71366497..74373822 [GRCh37]
Chr3:71449187..74456512 [NCBI36]
Chr3:3p13-12.3		 pathogenic
GRCh38/hg38 3p13(chr3:71124507-71892267)x3 copy number gain See cases [RCV000142251] Chr3:71124507..71892267 [GRCh38]
Chr3:71173658..71941418 [GRCh37]
Chr3:71256348..72024108 [NCBI36]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p13(chr3:71802608-71804290)x3 copy number gain See cases [RCV000446020] Chr3:71802608..71804290 [GRCh37]
Chr3:3p13		 pathogenic|uncertain significance
GRCh37/hg19 3p13-12.3(chr3:70127345-74508912)x3 copy number gain See cases [RCV000448203] Chr3:70127345..74508912 [GRCh37]
Chr3:3p13-12.3		 uncertain significance
NM_001134651.2(EIF4E3):c.29C>G (p.Pro10Arg) single nucleotide variant not specified [RCV004293179] Chr3:71725339 [GRCh38]
Chr3:71774490 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.530C>A (p.Pro177His) single nucleotide variant not specified [RCV004292088] Chr3:71754579 [GRCh38]
Chr3:71803730 [GRCh37]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p13-12.3(chr3:70433832-77012164)x1 copy number loss See cases [RCV000512368] Chr3:70433832..77012164 [GRCh37]
Chr3:3p13-12.3		 pathogenic
GRCh37/hg19 3p14.1-12.3(chr3:66133719-75076440)x1 copy number loss not provided [RCV000682270] Chr3:66133719..75076440 [GRCh37]
Chr3:3p14.1-12.3		 pathogenic
GRCh37/hg19 3p13(chr3:70618611-72399570)x1 copy number loss not provided [RCV000682271] Chr3:70618611..72399570 [GRCh37]
Chr3:3p13		 pathogenic
NM_018971.3(GPR27):c.691G>A (p.Gly231Ser) single nucleotide variant not specified [RCV004264146] Chr3:71754740 [GRCh38]
Chr3:71803891 [GRCh37]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p13(chr3:71758015-71821490)x1 copy number loss not provided [RCV000742511] Chr3:71758015..71821490 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71758015-71774311)x3 copy number gain not provided [RCV000742508] Chr3:71758015..71774311 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71758015-71774711)x3 copy number gain not provided [RCV000742509] Chr3:71758015..71774711 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71758015-71774736)x3 copy number gain not provided [RCV000742510] Chr3:71758015..71774736 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774185-71774736)x3 copy number gain not provided [RCV000742512] Chr3:71774185..71774736 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774185-71803728)x3 copy number gain not provided [RCV000742513] Chr3:71774185..71803728 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774185-71803887)x3 copy number gain not provided [RCV000742514] Chr3:71774185..71803887 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774185-71808566)x1 copy number loss not provided [RCV000742515] Chr3:71774185..71808566 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774211-71778737)x4 copy number gain not provided [RCV000742516] Chr3:71774211..71778737 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774238-71808566)x1 copy number loss not provided [RCV000742517] Chr3:71774238..71808566 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774291-71803887)x1 copy number loss not provided [RCV000742518] Chr3:71774291..71803887 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774291-71804138)x1 copy number loss not provided [RCV000742519] Chr3:71774291..71804138 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71774736-71804138)x1 copy number loss not provided [RCV000742520] Chr3:71774736..71804138 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71778737-71804138)x1 copy number loss not provided [RCV000742521] Chr3:71778737..71804138 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71801712-71808566)x1 copy number loss not provided [RCV000742522] Chr3:71801712..71808566 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71802672-71803887)x1 copy number loss not provided [RCV000742523] Chr3:71802672..71803887 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71802672-71804138)x1 copy number loss not provided [RCV000742524] Chr3:71802672..71804138 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71802672-71808566)x1 copy number loss not provided [RCV000742525] Chr3:71802672..71808566 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71802811-71803887)x1 copy number loss not provided [RCV000742526] Chr3:71802811..71803887 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71802811-71804138)x1 copy number loss not provided [RCV000742527] Chr3:71802811..71804138 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71802946-71803887)x1 copy number loss not provided [RCV000742528] Chr3:71802946..71803887 [GRCh37]
Chr3:3p13		 benign
GRCh37/hg19 3p13(chr3:71803001-71803887)x1 copy number loss not provided [RCV000742529] Chr3:71803001..71803887 [GRCh37]
Chr3:3p13		 benign
NM_001134651.2(EIF4E3):c.17C>T (p.Ala6Val) single nucleotide variant not specified [RCV004291715] Chr3:71725351 [GRCh38]
Chr3:71774502 [GRCh37]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p13-12.3(chr3:70938608-74660846)x3 copy number gain not provided [RCV001259675] Chr3:70938608..74660846 [GRCh37]
Chr3:3p13-12.3		 uncertain significance
Single allele deletion See cases [RCV001374461] Chr3:68965654..72679568 [GRCh37]
Chr3:3p14.1-13		 pathogenic
NM_018971.3(GPR27):c.495C>G (p.Asp165Glu) single nucleotide variant not specified [RCV004326917] Chr3:71754544 [GRCh38]
Chr3:71803695 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.152C>G (p.Ser51Trp) single nucleotide variant not specified [RCV004184826] Chr3:71725216 [GRCh38]
Chr3:71774367 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.18G>T (p.Glu6Asp) single nucleotide variant not specified [RCV004111222] Chr3:71754067 [GRCh38]
Chr3:71803218 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.656T>C (p.Leu219Pro) single nucleotide variant not specified [RCV004119554] Chr3:71754705 [GRCh38]
Chr3:71803856 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.136G>A (p.Glu46Lys) single nucleotide variant not specified [RCV004223888] Chr3:71754185 [GRCh38]
Chr3:71803336 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.13C>T (p.Pro5Ser) single nucleotide variant not specified [RCV004167764] Chr3:71725355 [GRCh38]
Chr3:71774506 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.523G>A (p.Val175Ile) single nucleotide variant not specified [RCV004090842] Chr3:71690115 [GRCh38]
Chr3:71739266 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.74C>T (p.Ala25Val) single nucleotide variant not specified [RCV004344143] Chr3:71725294 [GRCh38]
Chr3:71774445 [GRCh37]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p13(chr3:70583776-72793789)x1 copy number loss not specified [RCV003986401] Chr3:70583776..72793789 [GRCh37]
Chr3:3p13		 pathogenic
NM_001134651.2(EIF4E3):c.500G>A (p.Ser167Asn) single nucleotide variant not specified [RCV004377836] Chr3:71690138 [GRCh38]
Chr3:71739289 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.661C>T (p.Arg221Cys) single nucleotide variant not specified [RCV004377837] Chr3:71684696 [GRCh38]
Chr3:71733847 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.124C>T (p.Pro42Ser) single nucleotide variant not specified [RCV004377835] Chr3:71725244 [GRCh38]
Chr3:71774395 [GRCh37]
Chr3:3p13		 uncertain significance
NM_001134651.2(EIF4E3):c.118C>G (p.Leu40Val) single nucleotide variant not specified [RCV004377834] Chr3:71725250 [GRCh38]
Chr3:71774401 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.250G>T (p.Ala84Ser) single nucleotide variant not specified [RCV004391034] Chr3:71754299 [GRCh38]
Chr3:71803450 [GRCh37]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p13(chr3:71707206-72157556)x1 copy number loss not provided [RCV003485393] Chr3:71707206..72157556 [GRCh37]
Chr3:3p13		 uncertain significance
GRCh37/hg19 3p13(chr3:71665558-72020026)x3 copy number gain not provided [RCV001005444] Chr3:71665558..72020026 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.268C>G (p.Pro90Ala) single nucleotide variant not specified [RCV004356631] Chr3:71754317 [GRCh38]
Chr3:71803468 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.202G>A (p.Ala68Thr) single nucleotide variant not specified [RCV004365437] Chr3:71754251 [GRCh38]
Chr3:71803402 [GRCh37]
Chr3:3p13		 uncertain significance
NM_018971.3(GPR27):c.718G>A (p.Ala240Thr) single nucleotide variant not specified [RCV004346967] Chr3:71754767 [GRCh38]
Chr3:71803918 [GRCh37]
Chr3:3p13		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:8883
Count of miRNA genes:1320
Interacting mature miRNAs:1769
Transcripts:ENST00000295612, ENST00000389826, ENST00000421769, ENST00000425534, ENST00000448225, ENST00000468147, ENST00000469524, ENST00000481525, ENST00000496214, ENST00000497838
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D3S3551  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,778,889 - 71,779,138UniSTSGRCh37
Build 36371,861,579 - 71,861,828RGDNCBI36
Celera371,709,479 - 71,709,732RGD
Cytogenetic Map3p14UniSTS
HuRef371,781,003 - 71,781,256UniSTS
Marshfield Genetic Map399.38RGD
Marshfield Genetic Map399.38UniSTS
Genethon Genetic Map398.8UniSTS
TNG Radiation Hybrid Map346474.0UniSTS
deCODE Assembly Map396.78UniSTS
Whitehead-YAC Contig Map3 UniSTS
SHGC-77114  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,805,403 - 71,805,592UniSTSGRCh37
Build 36371,888,093 - 71,888,282RGDNCBI36
Celera371,735,996 - 71,736,185RGD
Cytogenetic Map3p14UniSTS
HuRef371,807,434 - 71,807,623UniSTS
TNG Radiation Hybrid Map346474.0UniSTS
GeneMap99-GB4 RH Map3216.95UniSTS
RH65929  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,731,932 - 71,732,172UniSTSGRCh37
Build 36371,814,622 - 71,814,862RGDNCBI36
Celera371,662,523 - 71,662,763RGD
Cytogenetic Map3p14UniSTS
HuRef371,734,217 - 71,734,457UniSTS
GeneMap99-GB4 RH Map3213.52UniSTS
RH80253  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,728,482 - 71,728,673UniSTSGRCh37
Build 36371,811,172 - 71,811,363RGDNCBI36
Celera371,659,073 - 71,659,264RGD
Cytogenetic Map3p14UniSTS
HuRef371,730,767 - 71,730,958UniSTS
GeneMap99-GB4 RH Map3212.81UniSTS
D3S1487  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,778,881 - 71,779,074UniSTSGRCh37
Build 36371,861,571 - 71,861,764RGDNCBI36
Celera371,709,471 - 71,709,668RGD
HuRef371,780,995 - 71,781,192UniSTS
D3S2775E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,733,363 - 71,733,457UniSTSGRCh37
Build 36371,816,053 - 71,816,147RGDNCBI36
Celera371,663,954 - 71,664,048RGD
Cytogenetic Map3p14UniSTS
HuRef371,735,647 - 71,735,741UniSTS
SHGC-144969  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,778,805 - 71,779,137UniSTSGRCh37
Build 36371,861,495 - 71,861,827RGDNCBI36
Celera371,709,395 - 71,709,731RGD
Cytogenetic Map3p14UniSTS
HuRef371,780,919 - 71,781,255UniSTS
TNG Radiation Hybrid Map346474.0UniSTS
WI-21047  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,728,461 - 71,728,707UniSTSGRCh37
Build 36371,811,151 - 71,811,397RGDNCBI36
Celera371,659,052 - 71,659,298RGD
Cytogenetic Map3p14UniSTS
HuRef371,730,746 - 71,730,992UniSTS
GeneMap99-GB4 RH Map3213.42UniSTS
Whitehead-RH Map3254.2UniSTS
A009C45  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,744,305 - 71,744,449UniSTSGRCh37
Build 36371,826,995 - 71,827,139RGDNCBI36
Celera371,674,894 - 71,675,038RGD
Cytogenetic Map3p14UniSTS
HuRef371,746,589 - 71,746,733UniSTS
GeneMap99-GB4 RH Map3211.81UniSTS
A008Y36  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,733,255 - 71,733,354UniSTSGRCh37
Build 36371,815,945 - 71,816,044RGDNCBI36
Celera371,663,846 - 71,663,945RGD
Cytogenetic Map3p14UniSTS
HuRef371,735,539 - 71,735,638UniSTS
GeneMap99-GB4 RH Map3211.97UniSTS
SHGC-77104  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,730,442 - 71,730,564UniSTSGRCh37
Build 36371,813,132 - 71,813,254RGDNCBI36
Celera371,661,033 - 71,661,155RGD
Cytogenetic Map3p14UniSTS
HuRef371,732,727 - 71,732,849UniSTS
TNG Radiation Hybrid Map346512.0UniSTS
GeneMap99-GB4 RH Map3214.93UniSTS
SHGC-77105  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,805,511 - 71,805,621UniSTSGRCh37
Build 36371,888,201 - 71,888,311RGDNCBI36
Celera371,736,104 - 71,736,214RGD
Cytogenetic Map3p14UniSTS
HuRef371,807,542 - 71,807,652UniSTS
TNG Radiation Hybrid Map346486.0UniSTS
GeneMap99-GB4 RH Map3214.93UniSTS
Whitehead-RH Map3253.3UniSTS
G32431  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37371,744,305 - 71,744,449UniSTSGRCh37
Celera371,674,894 - 71,675,038UniSTS
Cytogenetic Map3p14UniSTS
HuRef371,746,589 - 71,746,733UniSTS
D3S1487  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 1435 1036 431 5 686 4 1995 1494 1622 90 525 716 2 656 1461
Low 977 1942 1266 593 935 436 2344 687 2098 325 923 864 170 1 548 1327 4
Below cutoff 14 8 27 24 258 25 13 13 12 4 7 27 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001134650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001134651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_173359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011533651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC097634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK126999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL161983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA227887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA394405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN990553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DR159502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000295612   ⟹   ENSP00000295612
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,682,727 - 71,753,624 (-)Ensembl
RefSeq Acc Id: ENST00000389826   ⟹   ENSP00000374476
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,679,291 - 71,729,118 (-)Ensembl
RefSeq Acc Id: ENST00000421769   ⟹   ENSP00000411762
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,684,682 - 71,754,773 (-)Ensembl
RefSeq Acc Id: ENST00000425534   ⟹   ENSP00000393324
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,675,414 - 71,725,402 (-)Ensembl
RefSeq Acc Id: ENST00000448225   ⟹   ENSP00000410350
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,679,289 - 71,754,383 (-)Ensembl
RefSeq Acc Id: ENST00000468147
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,684,620 - 71,728,637 (-)Ensembl
RefSeq Acc Id: ENST00000469524   ⟹   ENSP00000419421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,693,897 - 71,728,720 (-)Ensembl
RefSeq Acc Id: ENST00000481525
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,684,541 - 71,728,650 (-)Ensembl
RefSeq Acc Id: ENST00000496214   ⟹   ENSP00000417889
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,693,875 - 71,754,383 (-)Ensembl
RefSeq Acc Id: ENST00000497838   ⟹   ENSP00000418211
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl371,690,041 - 71,729,197 (-)Ensembl
RefSeq Acc Id: NM_001134649   ⟹   NP_001128121
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,754,498 (-)NCBI
GRCh37371,728,440 - 71,803,924 (-)RGD
Celera371,659,031 - 71,734,517 (-)RGD
HuRef371,730,725 - 71,804,887 (-)NCBI
CHM1_1371,680,022 - 71,754,943 (-)NCBI
T2T-CHM13v2.0371,714,686 - 71,793,768 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001134650   ⟹   NP_001128122
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,679,289 - 71,729,118 (-)NCBI
GRCh37371,728,440 - 71,803,924 (-)RGD
Celera371,659,031 - 71,734,517 (-)RGD
HuRef371,730,725 - 71,804,887 (-)NCBI
CHM1_1371,680,022 - 71,729,699 (-)NCBI
T2T-CHM13v2.0371,718,561 - 71,768,389 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001134651   ⟹   NP_001128123
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,725,402 (-)NCBI
GRCh37371,728,440 - 71,803,924 (-)RGD
Celera371,659,031 - 71,734,517 (-)RGD
HuRef371,730,725 - 71,804,887 (-)NCBI
CHM1_1371,680,022 - 71,726,062 (-)NCBI
T2T-CHM13v2.0371,714,686 - 71,764,676 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001282886   ⟹   NP_001269815
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,753,591 (-)NCBI
HuRef371,730,725 - 71,804,887 (-)NCBI
CHM1_1371,680,022 - 71,754,224 (-)NCBI
T2T-CHM13v2.0371,714,686 - 71,792,858 (-)NCBI
Sequence:
RefSeq Acc Id: NM_173359   ⟹   NP_775495
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,754,773 (-)NCBI
GRCh37371,728,440 - 71,803,924 (-)RGD
Build 36371,814,568 - 71,885,465 (-)NCBI Archive
Celera371,659,031 - 71,734,517 (-)RGD
HuRef371,730,725 - 71,804,887 (-)NCBI
CHM1_1371,680,022 - 71,755,333 (-)NCBI
T2T-CHM13v2.0371,714,686 - 71,794,043 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011533651   ⟹   XP_011531953
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,725,402 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047448060   ⟹   XP_047304016
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,659,363 - 71,725,402 (-)NCBI
RefSeq Acc Id: XM_047448061   ⟹   XP_047304017
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,659,363 - 71,725,402 (-)NCBI
RefSeq Acc Id: XM_047448062   ⟹   XP_047304018
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,753,591 (-)NCBI
RefSeq Acc Id: XM_047448063   ⟹   XP_047304019
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,754,498 (-)NCBI
RefSeq Acc Id: XM_047448064   ⟹   XP_047304020
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,675,414 - 71,725,183 (-)NCBI
RefSeq Acc Id: XM_054346402   ⟹   XP_054202377
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0371,698,584 - 71,764,676 (-)NCBI
RefSeq Acc Id: XM_054346403   ⟹   XP_054202378
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0371,698,509 - 71,764,676 (-)NCBI
RefSeq Acc Id: XM_054346404   ⟹   XP_054202379
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0371,714,686 - 71,764,676 (-)NCBI
RefSeq Acc Id: XM_054346405   ⟹   XP_054202380
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0371,714,686 - 71,792,858 (-)NCBI
RefSeq Acc Id: XM_054346406   ⟹   XP_054202381
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0371,714,686 - 71,764,457 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001128121 (Get FASTA)   NCBI Sequence Viewer  
  NP_001128122 (Get FASTA)   NCBI Sequence Viewer  
  NP_001128123 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269815 (Get FASTA)   NCBI Sequence Viewer  
  NP_775495 (Get FASTA)   NCBI Sequence Viewer  
  XP_011531953 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304016 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304017 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304018 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304019 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304020 (Get FASTA)   NCBI Sequence Viewer  
  XP_054202377 (Get FASTA)   NCBI Sequence Viewer  
  XP_054202378 (Get FASTA)   NCBI Sequence Viewer  
  XP_054202379 (Get FASTA)   NCBI Sequence Viewer  
  XP_054202380 (Get FASTA)   NCBI Sequence Viewer  
  XP_054202381 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH31289 (Get FASTA)   NCBI Sequence Viewer  
  AAH68443 (Get FASTA)   NCBI Sequence Viewer  
  BAG36410 (Get FASTA)   NCBI Sequence Viewer  
  BAG54418 (Get FASTA)   NCBI Sequence Viewer  
  EAW65503 (Get FASTA)   NCBI Sequence Viewer  
  EAW65504 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000295612
  ENSP00000295612.3
  ENSP00000374476
  ENSP00000374476.3
  ENSP00000393324
  ENSP00000393324.2
  ENSP00000410350
  ENSP00000410350.1
  ENSP00000411762
  ENSP00000411762.2
  ENSP00000417889.2
  ENSP00000418211.1
  ENSP00000419421.1
GenBank Protein Q8N5X7 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_775495   ⟸   NM_173359
- Peptide Label: isoform b
- UniProtKB: Q8N5X7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128121   ⟸   NM_001134649
- Peptide Label: isoform b
- UniProtKB: Q8N5X7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128122   ⟸   NM_001134650
- Peptide Label: isoform b
- UniProtKB: Q8N5X7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128123   ⟸   NM_001134651
- Peptide Label: isoform a
- UniProtKB: B2R963 (UniProtKB/Swiss-Prot),   Q6NUT1 (UniProtKB/Swiss-Prot),   Q8N5X7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001269815   ⟸   NM_001282886
- Peptide Label: isoform b
- UniProtKB: Q8N5X7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011531953   ⟸   XM_011533651
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000393324   ⟸   ENST00000425534
RefSeq Acc Id: ENSP00000295612   ⟸   ENST00000295612
RefSeq Acc Id: ENSP00000374476   ⟸   ENST00000389826
RefSeq Acc Id: ENSP00000419421   ⟸   ENST00000469524
RefSeq Acc Id: ENSP00000417889   ⟸   ENST00000496214
RefSeq Acc Id: ENSP00000418211   ⟸   ENST00000497838
RefSeq Acc Id: ENSP00000410350   ⟸   ENST00000448225
RefSeq Acc Id: ENSP00000411762   ⟸   ENST00000421769
RefSeq Acc Id: XP_047304017   ⟸   XM_047448061
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047304016   ⟸   XM_047448060
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047304019   ⟸   XM_047448063
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047304018   ⟸   XM_047448062
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047304020   ⟸   XM_047448064
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054202378   ⟸   XM_054346403
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054202377   ⟸   XM_054346402
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054202380   ⟸   XM_054346405
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054202379   ⟸   XM_054346404
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054202381   ⟸   XM_054346406
- Peptide Label: isoform X4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8N5X7-F1-model_v2 AlphaFold Q8N5X7 1-224 view protein structure

Promoters
RGD ID:6864986
Promoter ID:EPDNEW_H5658
Type:initiation region
Name:EIF4E3_1
Description:eukaryotic translation initiation factor 4E family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5659  EPDNEW_H5660  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,725,402 - 71,725,462EPDNEW
RGD ID:6864988
Promoter ID:EPDNEW_H5659
Type:initiation region
Name:EIF4E3_3
Description:eukaryotic translation initiation factor 4E family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5658  EPDNEW_H5660  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,753,591 - 71,753,651EPDNEW
RGD ID:6864990
Promoter ID:EPDNEW_H5660
Type:initiation region
Name:EIF4E3_2
Description:eukaryotic translation initiation factor 4E family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5658  EPDNEW_H5659  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38371,754,773 - 71,754,833EPDNEW
RGD ID:6800659
Promoter ID:HG_KWN:45515
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:NB4
Transcripts:UC003DOV.2
Position:
Human AssemblyChrPosition (strand)Source
Build 36371,813,106 - 71,813,606 (-)MPROMDB
RGD ID:6800882
Promoter ID:HG_KWN:45516
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   NB4
Transcripts:NM_001134651
Position:
Human AssemblyChrPosition (strand)Source
Build 36371,856,741 - 71,858,192 (-)MPROMDB
RGD ID:6800883
Promoter ID:HG_KWN:45517
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour
Transcripts:NM_001134650
Position:
Human AssemblyChrPosition (strand)Source
Build 36371,861,674 - 71,862,174 (-)MPROMDB
RGD ID:6800881
Promoter ID:HG_KWN:45518
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:UC003DOX.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36371,885,711 - 71,886,211 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31837 AgrOrtholog
COSMIC EIF4E3 COSMIC
Ensembl Genes ENSG00000163412 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000295612 ENTREZGENE
  ENST00000295612.7 UniProtKB/Swiss-Prot
  ENST00000389826 ENTREZGENE
  ENST00000389826.7 UniProtKB/Swiss-Prot
  ENST00000421769 ENTREZGENE
  ENST00000421769.6 UniProtKB/Swiss-Prot
  ENST00000425534 ENTREZGENE
  ENST00000425534.8 UniProtKB/Swiss-Prot
  ENST00000448225 ENTREZGENE
  ENST00000448225.5 UniProtKB/Swiss-Prot
  ENST00000469524.1 UniProtKB/TrEMBL
  ENST00000496214.6 UniProtKB/TrEMBL
  ENST00000497838.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.760.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000163412 GTEx
HGNC ID HGNC:31837 ENTREZGENE
Human Proteome Map EIF4E3 Human Proteome Map
InterPro TIF_eIF4e-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIF_eIF_4E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:317649 UniProtKB/Swiss-Prot
NCBI Gene 317649 ENTREZGENE
OMIM 609896 OMIM
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11960 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IF4E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134961880 PharmGKB
Superfamily-SCOP SSF55418 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2R963 ENTREZGENE
  C9J6E5_HUMAN UniProtKB/TrEMBL
  C9J7Z6_HUMAN UniProtKB/TrEMBL
  C9JUY2_HUMAN UniProtKB/TrEMBL
  IF4E3_HUMAN UniProtKB/Swiss-Prot
  Q6NUT1 ENTREZGENE
  Q8N5X7 ENTREZGENE
UniProt Secondary B2R963 UniProtKB/Swiss-Prot
  Q6NUT1 UniProtKB/Swiss-Prot