Guf1 (GUF1 homolog, GTPase) - Rat Genome Database

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Gene: Guf1 (GUF1 homolog, GTPase) Mus musculus
Analyze
Symbol: Guf1
Name: GUF1 homolog, GTPase
RGD ID: 1332409
MGI Page MGI
Description: Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in positive regulation of translation. Predicted to act upstream of or within translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 40. Orthologous to human GUF1 (GTP binding elongation factor GUF1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4631409J12; AA407526; EF-4; elongation factor 4 homolog; GTP-binding protein GUF1 homolog; GTPase Guf1; GUF1 GTPase homolog; mtEF4; ribosomal back-translocase; translation factor Guf1, mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39569,714,255 - 69,731,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl569,714,266 - 69,733,316 (+)EnsemblGRCm39 Ensembl
GRCm38569,556,910 - 69,574,652 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl569,556,923 - 69,575,973 (+)EnsemblGRCm38mm10GRCm38
MGSCv37569,948,181 - 69,964,869 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36569,836,097 - 69,851,025 (+)NCBIMGSCv36mm8
Celera566,840,586 - 66,857,274 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map537.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:18614015   PMID:21677750   PMID:21873635   PMID:27065197   PMID:30550785  


Genomics

Comparative Map Data
Guf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39569,714,255 - 69,731,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl569,714,266 - 69,733,316 (+)EnsemblGRCm39 Ensembl
GRCm38569,556,910 - 69,574,652 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl569,556,923 - 69,575,973 (+)EnsemblGRCm38mm10GRCm38
MGSCv37569,948,181 - 69,964,869 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36569,836,097 - 69,851,025 (+)NCBIMGSCv36mm8
Celera566,840,586 - 66,857,274 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map537.13NCBI
GUF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38444,678,420 - 44,700,928 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl444,678,420 - 44,700,928 (+)EnsemblGRCh38hg38GRCh38
GRCh37444,680,437 - 44,702,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36444,375,190 - 44,397,454 (+)NCBINCBI36Build 36hg18NCBI36
Celera445,128,456 - 45,150,721 (+)NCBICelera
Cytogenetic Map4p12NCBI
HuRef444,002,095 - 44,024,321 (+)NCBIHuRef
CHM1_1444,679,550 - 44,701,808 (+)NCBICHM1_1
T2T-CHM13v2.0444,645,331 - 44,667,849 (+)NCBIT2T-CHM13v2.0
Guf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81438,891,905 - 38,911,283 (-)NCBIGRCr8
mRatBN7.21438,537,953 - 38,557,331 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1438,537,953 - 38,557,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1438,913,790 - 38,933,190 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01440,213,822 - 40,233,222 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01438,694,669 - 38,714,069 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01462,609,484 - 62,628,862 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1462,609,484 - 62,628,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01462,712,388 - 62,731,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41441,066,824 - 41,086,202 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11441,073,279 - 41,098,608 (-)NCBI
Celera1437,736,424 - 37,755,880 (-)NCBICelera
Cytogenetic Map14p11NCBI
Guf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554433,363,013 - 3,381,834 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554433,363,151 - 3,384,319 (-)NCBIChiLan1.0ChiLan1.0
GUF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2344,874,855 - 44,911,191 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1445,061,535 - 45,097,847 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0439,007,780 - 39,042,999 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1444,857,400 - 44,879,996 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl444,857,648 - 44,877,751 (+)Ensemblpanpan1.1panPan2
GUF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11341,183,708 - 41,208,203 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1341,183,172 - 41,204,970 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1341,135,951 - 41,161,312 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01341,790,183 - 41,815,559 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1341,790,110 - 41,812,275 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11341,469,708 - 41,495,063 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01341,514,614 - 41,539,986 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01341,907,113 - 41,932,489 (+)NCBIUU_Cfam_GSD_1.0
Guf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528534,899,766 - 34,918,442 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648211,379,992 - 11,398,345 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648211,379,747 - 11,398,385 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl835,167,622 - 35,190,584 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1835,167,615 - 35,190,587 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2836,873,410 - 36,896,376 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GUF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1275,590,810 - 5,611,171 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl275,590,912 - 5,611,230 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604751,734,558 - 51,759,206 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Guf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476122,285,876 - 22,308,913 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Guf1
346 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2043
Count of miRNA genes:755
Interacting mature miRNAs:968
Transcripts:ENSMUST00000031113, ENSMUST00000087228, ENSMUST00000125543, ENSMUST00000125660, ENSMUST00000132169, ENSMUST00000144363, ENSMUST00000154728, ENSMUST00000173205
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301223Hdlq7_mHDL QTL 7 (mouse)Not determined53585456869854714Mouse
13464252Ahl10_mage related hearing loss, early onset 10 (mouse)53585456869854714Mouse
4141647Hrvhf1_mheart rate variability, high frequency 1 (mouse)Not determined3643342370433423Mouse
1301170Lith13_mlithogenic gene 13 (mouse)Not determined53649448670494598Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
13464246Ahl11_mage related hearing loss, early onset 11 (mouse)53764377771643896Mouse
1300951Gbvq1_mgallstone bladder volume QTL 1 (mouse)Not determined53811168172111798Mouse
13464245Ahl12_mage related hearing loss, early onset 12 (mouse)53811168172111798Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54458584378585965Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54632260680322606Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54632260680322606Mouse
14746981Manh57_mmandible shape 57 (mouse)54716974281169742Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
13464248Ahl13_mage related hearing loss, early onset 13 (mouse)55564587489645995Mouse
10043962Obq27_mobesity QTL 27 (mouse)Not determined55628565590285655Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55833050292330641Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse

Markers in Region
RH124611  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38569,571,586 - 69,571,701UniSTSGRCm38
MGSCv37569,962,825 - 69,962,940UniSTSGRCm37
Celera566,855,230 - 66,855,345UniSTS
Cytogenetic Map5C3.1UniSTS
Gnpda2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map5DUniSTS
cM Map537.13UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004942496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004942497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY743247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000031113   ⟹   ENSMUSP00000031113
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,331 - 69,729,074 (+)Ensembl
GRCm38.p6 Ensembl569,556,988 - 69,571,731 (+)Ensembl
RefSeq Acc Id: ENSMUST00000087228   ⟹   ENSMUSP00000084480
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,304 - 69,730,447 (+)Ensembl
GRCm38.p6 Ensembl569,556,961 - 69,573,104 (+)Ensembl
RefSeq Acc Id: ENSMUST00000125543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,296 - 69,724,052 (+)Ensembl
GRCm38.p6 Ensembl569,556,953 - 69,566,709 (+)Ensembl
RefSeq Acc Id: ENSMUST00000125660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,724,067 - 69,733,316 (+)Ensembl
GRCm38.p6 Ensembl569,566,724 - 69,575,973 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132169   ⟹   ENSMUSP00000144290
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,296 - 69,724,212 (+)Ensembl
GRCm38.p6 Ensembl569,556,953 - 69,566,869 (+)Ensembl
RefSeq Acc Id: ENSMUST00000144363   ⟹   ENSMUSP00000114707
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,416 - 69,725,068 (+)Ensembl
GRCm38.p6 Ensembl569,557,073 - 69,567,725 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154728   ⟹   ENSMUSP00000144246
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,266 - 69,729,073 (+)Ensembl
GRCm38.p6 Ensembl569,556,923 - 69,571,730 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173205   ⟹   ENSMUSP00000133467
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,714,437 - 69,729,118 (+)Ensembl
GRCm38.p6 Ensembl569,557,094 - 69,571,775 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202180
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl569,727,534 - 69,728,826 (+)Ensembl
GRCm38.p6 Ensembl569,570,191 - 69,571,483 (+)Ensembl
RefSeq Acc Id: NM_001310631   ⟹   NP_001297560
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39569,714,267 - 69,731,995 (+)NCBI
GRCm38569,556,924 - 69,574,652 (+)NCBI
Sequence:
RefSeq Acc Id: NM_172711   ⟹   NP_766299
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39569,714,267 - 69,731,995 (+)NCBI
GRCm38569,556,924 - 69,574,652 (+)NCBI
MGSCv37569,948,181 - 69,964,869 (+)RGD
Celera566,840,586 - 66,857,274 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006503948   ⟹   XP_006504011
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39569,717,788 - 69,730,974 (+)NCBI
GRCm38569,560,445 - 69,573,631 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004942496
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39569,714,255 - 69,730,974 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004942497
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39569,714,255 - 69,730,974 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_766299   ⟸   NM_172711
- Peptide Label: isoform 1
- UniProtKB: Q6PEN7 (UniProtKB/Swiss-Prot),   Q8BPS6 (UniProtKB/Swiss-Prot),   Q8C3X4 (UniProtKB/Swiss-Prot),   G3UWY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006504011   ⟸   XM_006503948
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001297560   ⟸   NM_001310631
- Peptide Label: isoform 2
- UniProtKB: G3UWY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000114707   ⟸   ENSMUST00000144363
RefSeq Acc Id: ENSMUSP00000031113   ⟸   ENSMUST00000031113
RefSeq Acc Id: ENSMUSP00000144290   ⟸   ENSMUST00000132169
RefSeq Acc Id: ENSMUSP00000084480   ⟸   ENSMUST00000087228
RefSeq Acc Id: ENSMUSP00000144246   ⟸   ENSMUST00000154728
RefSeq Acc Id: ENSMUSP00000133467   ⟸   ENSMUST00000173205
Protein Domains
tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C3X4-F1-model_v2 AlphaFold Q8C3X4 1-651 view protein structure

Promoters
RGD ID:6886830
Promoter ID:EPDNEW_M6866
Type:initiation region
Name:Guf1_1
Description:Mus musculus GUF1 homolog, GTPase , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38569,556,973 - 69,557,033EPDNEW
RGD ID:6837707
Promoter ID:MM_KWN:42487
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK014107_3110031N09RIK,   ENSMUST00000031113,   ENSMUST00000066129,   OTTMUST00000068707,   OTTMUST00000068708,   OTTMUST00000068709,   OTTMUST00000068710,   UC008XQL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36569,947,906 - 69,948,406 (+)MPROMDB
RGD ID:6837688
Promoter ID:MM_KWN:42488
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000068713
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36569,958,901 - 69,959,401 (+)MPROMDB
RGD ID:6837167
Promoter ID:MM_KWN:42489
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:UC008XQO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36569,963,366 - 69,963,866 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2140726 AgrOrtholog
Ensembl Genes ENSMUSG00000029208 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031113 ENTREZGENE
  ENSMUST00000031113.13 UniProtKB/Swiss-Prot
  ENSMUST00000087228 ENTREZGENE
  ENSMUST00000087228.11 UniProtKB/Swiss-Prot
  ENSMUST00000132169.8 UniProtKB/TrEMBL
  ENSMUST00000144363.8 UniProtKB/TrEMBL
  ENSMUST00000154728.8 UniProtKB/TrEMBL
  ENSMUST00000173205.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.2570 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Elongation Factor G (Translational Gtpase), domain 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_III/V UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFG_V-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFTu-like_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_TR_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LepA_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LepA_CTD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LepA_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:231279 UniProtKB/Swiss-Prot
MGD MGI:2140726 ENTREZGENE
NCBI Gene 231279 ENTREZGENE
PANTHER PTHR43512 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSLATION FACTOR GUF1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EFG_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LepA_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Guf1 PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_TR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_TR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YUM0_MOUSE UniProtKB/TrEMBL
  F6ZM03_MOUSE UniProtKB/TrEMBL
  G3UWY0 ENTREZGENE, UniProtKB/TrEMBL
  GUF1_MOUSE UniProtKB/Swiss-Prot
  Q6PEN7 ENTREZGENE
  Q8BPS6 ENTREZGENE
  Q8C3X4 ENTREZGENE
  Q8C8D6_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q6PEN7 UniProtKB/Swiss-Prot
  Q8BPS6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Guf1  GUF1 homolog, GTPase    GUF1 GTPase homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED