2310057J18Rik (RIKEN cDNA 2310057J18 gene) - Rat Genome Database

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Gene: 2310057J18Rik (RIKEN cDNA 2310057J18 gene) Mus musculus
Analyze
Symbol: 2310057J18Rik
Name: RIKEN cDNA 2310057J18 gene
RGD ID: 1323645
MGI Page MGI
Description: Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human C6orf58 (chromosome 6 open reading frame 58).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2210414P04Rik; hypothetical protein LOC67719; Leg1; UPF0762 protein C6orf58 homolog
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391028,848,284 - 28,862,302 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1028,848,284 - 28,862,299 (-)EnsemblGRCm39 Ensembl
GRCm381028,972,288 - 28,986,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1028,972,288 - 28,986,303 (-)EnsemblGRCm38mm10GRCm38
MGSCv371028,692,094 - 28,706,112 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361028,661,781 - 28,675,719 (-)NCBIMGSCv36mm8
Celera1029,903,690 - 29,917,734 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750   PMID:21873635   PMID:30973865  


Genomics

Comparative Map Data
2310057J18Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391028,848,284 - 28,862,302 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1028,848,284 - 28,862,299 (-)EnsemblGRCm39 Ensembl
GRCm381028,972,288 - 28,986,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1028,972,288 - 28,986,303 (-)EnsemblGRCm38mm10GRCm38
MGSCv371028,692,094 - 28,706,112 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361028,661,781 - 28,675,719 (-)NCBIMGSCv36mm8
Celera1029,903,690 - 29,917,734 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.46NCBI
C6orf58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,577,174 - 127,591,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,519,455 - 127,591,820 (+)EnsemblGRCh38hg38GRCh38
GRCh376127,898,319 - 127,912,965 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366127,940,012 - 127,954,655 (+)NCBINCBI36Build 36hg18NCBI36
Celera6128,640,558 - 128,655,201 (+)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,474,561 - 125,489,205 (+)NCBIHuRef
CHM1_16128,162,764 - 128,177,408 (+)NCBICHM1_1
T2T-CHM13v2.06128,766,100 - 128,780,746 (+)NCBIT2T-CHM13v2.0
Leg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,628,501 - 30,644,590 (+)NCBIGRCr8
mRatBN7.2128,799,902 - 28,816,230 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,799,902 - 28,815,993 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0131,409,579 - 31,425,669 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,409,579 - 31,425,662 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0132,835,727 - 32,851,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,599,530 - 29,615,619 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,605,775 - 29,609,624 (+)NCBI
Celera127,451,634 - 27,468,035 (+)NCBICelera
Cytogenetic Map1p11NCBI
C5H6orf58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,564,197 - 147,585,452 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,472,936 - 145,494,196 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06125,364,933 - 125,379,554 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,477,073 - 129,491,689 (+)NCBIpanpan1.1PanPan1.1panPan2
C1H6orf58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,270,546 - 66,281,079 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,270,567 - 66,289,965 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,075,581 - 67,088,554 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,479,431 - 66,492,393 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,479,476 - 66,498,855 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,402,715 - 66,415,660 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,187,435 - 66,200,389 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,829,782 - 66,842,747 (+)NCBIUU_Cfam_GSD_1.0
LOC100511607
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1135,600,478 - 35,621,276 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2139,226,172 - 39,246,973 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH6orf58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11346,094,903 - 46,114,454 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1346,095,091 - 46,113,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604018,343,383 - 18,362,347 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in 2310057J18Rik
532 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:74
Interacting mature miRNAs:77
Transcripts:ENSMUST00000015663, ENSMUST00000140558, ENSMUST00000141350, ENSMUST00000152363
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10440815438408276Mouse
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
1301796Mop2_mmorphine preference 2 (mouse)Not determined10928911929028424Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1558857Igan1_mIgA nephropathy 1 (mouse)Not determined101771831329704155Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102689026446720483Mouse

Markers in Region
AI058682  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381028,984,980 - 28,985,099UniSTSGRCm38
MGSCv371028,704,786 - 28,704,905UniSTSGRCm37
Celera1029,916,408 - 29,916,527UniSTS
Cytogenetic Map10A4UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC153798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000015663   ⟹   ENSMUSP00000015663
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1028,848,362 - 28,862,299 (-)Ensembl
GRCm38.p6 Ensembl1028,972,366 - 28,986,303 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140558   ⟹   ENSMUSP00000121044
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1028,848,284 - 28,861,380 (-)Ensembl
GRCm38.p6 Ensembl1028,972,288 - 28,985,384 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141350
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1028,848,362 - 28,850,185 (-)Ensembl
GRCm38.p6 Ensembl1028,972,366 - 28,974,189 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152363   ⟹   ENSMUSP00000118049
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1028,848,360 - 28,862,289 (-)Ensembl
GRCm38.p6 Ensembl1028,972,364 - 28,986,293 (-)Ensembl
RefSeq Acc Id: NM_026336   ⟹   NP_080612
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391028,848,284 - 28,862,302 (-)NCBI
GRCm381028,972,288 - 28,986,306 (-)ENTREZGENE
MGSCv371028,692,094 - 28,706,112 (-)RGD
Celera1029,903,690 - 29,917,734 (-)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_080612   ⟸   NM_026336
- Peptide Label: precursor
- UniProtKB: Q9D7F4 (UniProtKB/Swiss-Prot),   Q9D775 (UniProtKB/Swiss-Prot),   Q9D745 (UniProtKB/Swiss-Prot),   Q9D6S4 (UniProtKB/Swiss-Prot),   Q9CQ55 (UniProtKB/Swiss-Prot),   Q9CPV8 (UniProtKB/Swiss-Prot),   Q8VDJ0 (UniProtKB/Swiss-Prot),   Q8C6D6 (UniProtKB/Swiss-Prot),   Q8C6D2 (UniProtKB/Swiss-Prot),   Q9D865 (UniProtKB/Swiss-Prot),   Q8C6C9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000015663   ⟸   ENSMUST00000015663
RefSeq Acc Id: ENSMUSP00000118049   ⟸   ENSMUST00000152363
RefSeq Acc Id: ENSMUSP00000121044   ⟸   ENSMUST00000140558

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C6C9-F1-model_v2 AlphaFold Q8C6C9 1-337 view protein structure

Promoters
RGD ID:8671718
Promoter ID:EPDNEW_M13890
Type:multiple initiation site
Name:2310057J18Rik_1
Description:Mus musculus RIKEN cDNA 2310057J18 gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381028,986,303 - 28,986,363EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914969 AgrOrtholog
Ensembl Genes ENSMUSG00000015519 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000015663 ENTREZGENE
  ENSMUST00000015663.7 UniProtKB/Swiss-Prot
  ENSMUST00000140558.8 UniProtKB/TrEMBL
  ENSMUST00000152363.8 UniProtKB/TrEMBL
InterPro Leg1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67719 UniProtKB/Swiss-Prot
MGD MGI:1914969 ENTREZGENE
NCBI Gene 67719 ENTREZGENE
PANTHER PROTEIN LEG1 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Leg1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen 2310057J18Rik PhenoGen
UniProt D3YTP1_MOUSE UniProtKB/TrEMBL
  D3Z001_MOUSE UniProtKB/TrEMBL
  LEG1H_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C6D2 ENTREZGENE
  Q8C6D6 ENTREZGENE
  Q8VDJ0 ENTREZGENE
  Q9CPV8 ENTREZGENE
  Q9CQ55 ENTREZGENE
  Q9D6S4 ENTREZGENE
  Q9D745 ENTREZGENE
  Q9D775 ENTREZGENE
  Q9D7F4 ENTREZGENE
  Q9D865 ENTREZGENE
UniProt Secondary Q8C6D2 UniProtKB/Swiss-Prot
  Q8C6D6 UniProtKB/Swiss-Prot
  Q8VDJ0 UniProtKB/Swiss-Prot
  Q9CPV8 UniProtKB/Swiss-Prot
  Q9CQ55 UniProtKB/Swiss-Prot
  Q9D6S4 UniProtKB/Swiss-Prot
  Q9D745 UniProtKB/Swiss-Prot
  Q9D775 UniProtKB/Swiss-Prot
  Q9D7F4 UniProtKB/Swiss-Prot
  Q9D865 UniProtKB/Swiss-Prot