Nt5el (5' nucleotidase, ecto-like) - Rat Genome Database

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Gene: Nt5el (5' nucleotidase, ecto-like) Mus musculus
Analyze
Symbol: Nt5el
Name: 5' nucleotidase, ecto-like
RGD ID: 1323407
MGI Page MGI
Description: Predicted to enable XMP 5'-nucleosidase activity. Orthologous to human NT5ELP (5' nucleotidase, ecto-like, pseudogene).
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: 4933425L06Rik; hypothetical protein LOC66763; MGC141320; RIKEN cDNA 4933425L06 gene; uncharacterized protein LOC66763
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913105,218,630 - 105,258,290 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13105,218,630 - 105,258,290 (+)EnsemblGRCm39 Ensembl
GRCm3813105,082,122 - 105,121,782 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13105,082,122 - 105,121,782 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713105,872,202 - 105,911,862 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613106,202,504 - 106,242,164 (+)NCBIMGSCv36mm8
Celera13109,476,898 - 109,516,556 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750   PMID:24652767   PMID:30973865  


Genomics

Comparative Map Data
Nt5el
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913105,218,630 - 105,258,290 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13105,218,630 - 105,258,290 (+)EnsemblGRCm39 Ensembl
GRCm3813105,082,122 - 105,121,782 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13105,082,122 - 105,121,782 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713105,872,202 - 105,911,862 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613106,202,504 - 106,242,164 (+)NCBIMGSCv36mm8
Celera13109,476,898 - 109,516,556 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.92NCBI
NT5ELP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p14 Ensembl564,404,512 - 64,486,615 (-)EnsemblGRCh38hg38GRCh38
Cytogenetic Map5q12.3NCBI

Variants

.
Variants in Nt5el
1455 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:62
Interacting mature miRNAs:63
Transcripts:ENSMUST00000022232
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87901985112431103Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394528399120883175Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1395036824120883175Mouse
1357468Rplag_mreduced platelet aggregation (mouse)Not determined1395502130120883175Mouse
14746974Manh75_mmandible shape 75 (mouse)1399386647120883175Mouse
4141102Sod1m_msuperoxide dismutase 1, soluble, modifier (mouse)Not determined99739968110699911Mouse
12879496Fexq2_mfear expression QTL 2 (mouse)13100741519120883175Mouse
13824989Pbsq1_mpercent broken sperm QTL 1 (mouse)13102136508112136534Mouse
4142400Tgq24_mtriglyceride QTL 24 (mouse)Not determined102602630120883175Mouse
25394543Skmw79_mskeletal muscle weight 79, soleus (mouse)13103286625107663775Mouse
4141826Tbqt5_mtibia bone quality traits 5 (mouse)Not determined13103341617117043216Mouse
25394542Skmw80_mskeletal muscle weight 80, TA (mouse)13104397730107663775Mouse
25394544Skmw78_mskeletal muscle weight 78, gastroc (mouse)13104397730107663775Mouse
25394545Skmw77_mskeletal muscle weight 77, EDL (mouse)13104421423107663775Mouse
13513920Heal57_mwound healing/ regeneration 57 (mouse)13104450757107073998Mouse

Markers in Region
21.MMHAP15FRG9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3813105,106,772 - 105,106,948UniSTSGRCm38
MGSCv3713105,896,852 - 105,897,028UniSTSGRCm37
Celera13109,501,551 - 109,501,727UniSTS
Cytogenetic Map13D1UniSTS
Whitehead_YAC13 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022232   ⟹   ENSMUSP00000022232
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13105,218,630 - 105,258,290 (+)Ensembl
GRCm38.p6 Ensembl13105,082,122 - 105,121,782 (+)Ensembl
RefSeq Acc Id: NM_025751   ⟹   NP_080027
RefSeq Status: PREDICTED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913105,218,630 - 105,258,290 (+)NCBI
GRCm3813105,082,122 - 105,121,782 (+)ENTREZGENE
MGSCv3713105,872,202 - 105,911,862 (+)RGD
Celera13109,476,898 - 109,516,556 (+)RGD
cM Map13 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_080027 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI19577 (Get FASTA)   NCBI Sequence Viewer  
  AAI19578 (Get FASTA)   NCBI Sequence Viewer  
  BAB30414 (Get FASTA)   NCBI Sequence Viewer  
  BAB30497 (Get FASTA)   NCBI Sequence Viewer  
  EDL18484 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000022232
  ENSMUSP00000022232.6
Reference Protein Sequences
RefSeq Acc Id: NP_080027   ⟸   NM_025751
- UniProtKB: Q9D3Z8 (UniProtKB/TrEMBL),   Q9D469 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000022232   ⟸   ENSMUST00000022232
Protein Domains
5'-Nucleotidase C-terminal   Calcineurin-like phosphoesterase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D3Z8-F1-model_v2 AlphaFold Q9D3Z8 1-585 view protein structure

Promoters
RGD ID:8681240
Promoter ID:EPDNEW_M18651
Type:initiation region
Name:4933425L06Rik_1
Description:Mus musculus RIKEN cDNA 4933425L06 gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3813105,082,122 - 105,082,182EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914013 AgrOrtholog
Ensembl Genes ENSMUSG00000021718 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022232 ENTREZGENE
  ENSMUST00000022232.6 UniProtKB/TrEMBL
Gene3D-CATH 3.60.21.10 UniProtKB/TrEMBL
  3.90.780.10 UniProtKB/TrEMBL
InterPro 5'-Nucleotdase_C UniProtKB/TrEMBL
  5'-Nucleotdase_C_sf UniProtKB/TrEMBL
  5_nucleotidase/apyrase UniProtKB/TrEMBL
  CG11883_N UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/TrEMBL
  Metallo_PEstase_dom UniProtKB/TrEMBL
KEGG Report mmu:66763 UniProtKB/TrEMBL
MGD MGI:1914013 ENTREZGENE
NCBI Gene 66763 ENTREZGENE
PANTHER 5' NUCLEOTIDASE, ECTO-LIKE UniProtKB/TrEMBL
  5_nucleotidase UniProtKB/TrEMBL
Pfam 5_nucleotid_C UniProtKB/TrEMBL
  Metallophos UniProtKB/TrEMBL
PhenoGen Nt5el PhenoGen
PRINTS APYRASEFAMLY UniProtKB/TrEMBL
Superfamily-SCOP 5'-Nucleotdase_C UniProtKB/TrEMBL
  SSF56300 UniProtKB/TrEMBL
UniProt Q9D3Z8 ENTREZGENE, UniProtKB/TrEMBL
  Q9D469 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-20 Nt5el  5' nucleotidase, ecto-like  4933425L06Rik  RIKEN cDNA 4933425L06 gene  Symbol and/or name change 5135510 APPROVED